AVIAN INFLUENZA IN ISRAEL (Date of previous outbreak of highly pathogenic avian influenza in Israel reported to the OIE: 1988). Immediate notification report Information received on 16, 17 and 18 March 2006 from Dr Moshe Chaimovitz, Director of Veterinary and Animal Health Services, Ministry of Agriculture and Rural Development, Beit-Dagan: Report date: 18 March 2006. Reason for immediate notification: re-occurrence of a listed disease or infection in a country following a report declaring the outbreak(s) ended. Identification of agent: highly pathogenic avian influenza virus subtype H5N1. Date of first confirmation of the event: 16 March 2006. Date of start of the event: 16 March 2006. Clinical disease: yes. Nature of diagnosis: clinical, post-mortem and laboratory. Details of outbreaks: Type First Lower of administrative administrative epidedivision division miolo(region) (district) gical unit Name of the location Number of animals in the outbreaks Date of start of Spethe cies susceptible cases deaths destroyed slaughtered outbreak HaDarom Beer-Sheva farm En Hashelosha 16 March 2006 avi 12,000 1,800 1,800 10,200 0 HaDarom Beer-Sheva farm Holit 16 March 2006 avi 30,000 9,000 9,000 21,000 0 HaDarom Ashkelon 17 March 2006 avi 6,500 500 500 6,000 0 Jesuralem Jesuralem 17 March 2006 avi 20,000 500 500 19,500 0 village Sede Moshe farm Nahshon Description of affected population: fattening turkeys 16 weeks old. Diagnosis: Laboratory Location of Species where diagnostic the examined tests were outbreak(s) performed Kimron Veterinary Institute, Beit Dagan En Hashelosha, Holit and Sede Moshe Nahshon turkey turkey Diagnostic tests used Date Results PCR(1) (H5) 16 March 2006 positive PCR (H5N1) 17 and 18 March 2006 positive virus isolation 18 March 2006 positive haemagglutination test (HA) 18 March 2006 positive haemagglutination inhibition test (HI) 18 March 2006 positive PCR (H5) 18 March 2006 positive PCR (N1) 18 March 2006 pending PCR (H5N1) 18 March 2006 positive - virus isolation; 18 March 2006 pending - HI. Source of outbreaks or origin of infection: unknown or inconclusive. Control measures undertaken: - stamping out (all birds in the affected flocks have been destroyed and buried); - quarantine; - movement restrictions enforced within a 3-km-radius around the outbreaks; - screening; - zoning. Treatment of affected animals: no. Other details/comments: epidemiological surveys are underway in a 10km-radius zone around the outbreaks. Final report: no. (1) PCR: polymerase chain reaction