OIE Collaborating Centre Reports Activities in 2010 Title of Collaborating Centre: Address of Collaborating Centre: Diagnosis and Control of Animal Disease and Related Veterinary Product Assessment in Asia (1): National Institute of Animal Health (NIAH), 3-1-5, Kannondai, Tsukuba, Ibaraki, 305-0856, JAPAN (2): National Veterinary Assay Laboratory (NVAL), 1-15-1, Tokura, Kokubunji, Tokyo, 185-8511, JAPAN Tel.: (1): (+81-29) 838.77.13 (2): (+81-42) 321.14.41 Fax: (1): (+81-29) 838.78.80 (2): (+81-42) 325.51.22 e-mail address: (1): skenichi@affrc.go.jp (2): nval@nval.maff.go.jp website: (1): http://niah.naro.affrc.go.jp/index.html (2): http://www.maff.go.jp/nval/ Name of Head of Centre (Responsible Official): (1) Takafumi Hamaoka Director General (NIAH) (2) Masato Sakai Director General (NVAL) Name of OIE Contact Point: Kenichi Sakamoto Research Manager(NIAH) Name of writer of this report (if different from above) Annual reports of OIE Reference Laboratories and Collaborating Centres, 2010 1 Diagnosis and Control of Animal Disease and Related Veterinary Product Assessment in Asia Part I: Summary of activities specifically related to the mandate of OIE Collaborating Centres 1. Activities as a centre of research, expertise, standardisation and dissemination of techniques within the remit of the mandate given by the OIE ・ Participated as a representative in Japan for “The First Central Laboratory Directors’ Meeting in Malaysia” (Japan, Thailand, Cambodia, Indonesia, Laos, Malaysia, Mongolia, Myanmar, Vietnam) ・ Participated as a representative in Japan for “The Second Central Laboratory Directors’ Meeting in Thailand” (Japan, Thailand, Cambodia, Laos, Malaysia, Myanmar, Vietnam) and pronounced to prevention of FMD outbreak in Japan, 2010” and election of OIE collaborating centre. ・ ・ 2. 2 Provided research material to member countries(Cambodia, P.R. China, Korea) Training on the livestock hygiene to member countries(P.R. China, Thailand, Bangladesh, Vietnam, Tanzania) ・ Met with public laboratories personnel from Korea and Kirgiz to provide information on FMD etc. ・ pronounced to prevention of FMD outbreak in Japan “FMD week 2010” held in Austria. ・ Attending Second Global Conference of OIE Reference laboratories and Collaborating Centres. 21-23, May 2010, Paris France. ・ Participation and two scientific presentations on the FMD control in FMD International Symposium and Workshop 12-14, April 2010, Melbourne Australia ・ Presentation and technical advice to Taiwan. Bureau of Animal and Plant Health Inspection and Quarantine Council. “Regulations and Approval Procedures for Veterinary Drugs and National Assay for Fish Vaccines in Japan.”Taipei, Taiwan, August 24-26, 2010. ・ 14th Animal Science Congress of Asian Australasian of Animal Production Societies. “Outline and Japanese Regulation of Veterinary Drug Residues in Food”. Pingtung, Taiwan, August 23-27, 2010 ・ Planning Mission for New Technical Cooperation Project on Animal Health Control in Indonesia. Indonesia, October 3-29, 2010. Proposal or development of any procedure that will facilitate harmonisation of international regulations applicable to the surveillance and control of animal diseases, food safety or animal welfare 1. National Veterinary Assay Laboratory (NVAL) participated in the conferences of OIE. ・ Second Global Conference of OIE Reference Laboratories and Collaborating Centres. Paris, FRANCE, June 21-23, 2010. ・ OIE ad hoc Group on Antimicrobial Resistance OIE Headquarters. Paris, FRANCE, November 2-4, 2010. 2. NVAL plays a part in the conferences on International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Products (VICH). ・ Expert working group (EWG) meeting of VICH Pharmacovigilance. London, UK, June 16-22, 2010. Annual reports of OIE Reference Laboratories and Collaborating Centres, 2010 Diagnosis and Control of Animal Disease and Related Veterinary Product Assessment in Asia ・ The 4th public conference on VICH. Paris, FRANCE, June 24-25, 2010. ・ The 24th Meeting of VICH. Paris, FRANCE, June 23 &26, 2010. ・ The 3rd Meeting of VICH EWG on Metabolism and Residue Kinetics. Washington, DC, US, October 6-8, 2010. ・ The 1st Meeting of VICH EWG on Safety. Washington, DC, US, October 25-26, 2010. 3. NVAL plays a part in the conferences on Joint FAO/WHO Food Standards Programme ・ 3. The 19th Session of the CODEX Committee on Residues of Veterinary Drugs in Foods (CCRVDF). Burlington, US, August 30-September 3, 2010. Placement of expert consultants at the disposal of the OIE ・ Participated in the 4th OIE/FAO-APHCA Regional Workshop and Working Group Meeting on BSE and Other Prion Diseases, in collaboration with NVRQS, MIFAFF, held in Seoul, Republic of Korea, 24-26 February 2010. (P.R. China, India, Korea, Malaysia, Mongolia, Philippines, Thailand) ・ Participated in the Third OIE Regional Expert Group Meeting for Implementation of the Programme on Surveillance of Wild Birds and Domestic Animals along Migratory Flyways under the OIE/JTF Project for Strengthening HPAI Control in Asia, held in Tokyo, Japan, 16-17 June 2010. (Bangladesh, Bhutan, P.R. China, Hong Kong SAR, P.R. China, Japan, Laos, Mongolia, Nepal, Vietnam) ・ Participated in the FAO-APHCA/OIE Regional Workshop on BSE Risk Status Recognition (under the context of WTO-SPS Agreement) and Interim BSE Working Group Meeting, held in Chang Mai, Thailand, 31 August - 3 September 2010. (Cambodia, P.R. China, India, Indonesia, Japan, R.O. Korea, Laos, Malaysia, Mongolia, Myanmar, Philippines, Thailand, Vietnam) ・ Participated in the 3rd OIE Regional Meeting on Strengthening Animal Health Information Networking in Asia under the OIE/JTF Project for Strengthening HPAI Control in Asia, held in Tokyo, Japan, 15-16 September 2010. (Bangladesh, Bhutan, Brunei, Cambodia, P.R. China, Chinese Taipei, Hong Kong SAR, India, Indonesia, Japan, Korea, Laos, Malaysia, Maldives, Mongolia, Myanmar, Nepal, Philippines, Singapore, Sri Lanka, Thailand, Vietnam) ・ Participation of the meeting of OIE Scientific Commission for Animal disease, 1-4 February 2011 Part II: Other activities related to the mandate of OIE Collaborating Centres 4. Provision of scientific and technical training, within the remit of the mandate given by the OIE, to personnel from OIE Members ・ In March-October 2010, NIAH staff trained two scientists from Indonesia and Uganda in improvement diagnostic methods for hemoparasite infections. ・ In March-October 2010, NIAH staff trained a scientist from Indonesia in research on diagnostic technology of production disease. ・ In March-October 2010, NIAH staff trained a scientist from Zambia in study on pathological diagnosis methods for diseases of domestic animals. ・ Seminar for Food Safety Policy Planning and Management (Target regions or countries: P.R. China, Mexico, Chile, Jordan, Serbia and Ukraine). A lecture of the regulations on agriculture, livestock and fishery products, “Regulations and Approval Procedures for Veterinary drugs in Japan.” Tokyo, Japan, September 6, 2010. Annual reports of OIE Reference Laboratories and Collaborating Centres, 2010 3 Diagnosis and Control of Animal Disease and Related Veterinary Product Assessment in Asia 5. Organisation of scientific meetings on behalf of the OIE NVAL and NIAH are preparing to hold the regional Workshop on Risk Analysis for Veterinary Vaccines, March 1-3 2011, Tokyo, Japan. 6. Coordination of scientific and technical studies in collaboration with other laboratories, orgnisations or collaborating centres ・ Collaboration with Thailand on a project entitled “Epidemiological Research Collaboration on Avian Influenza and Zoonotic Diseases in Thailand and Neighboring Countries” ・ Collaboration with Thailand on a project entitled “Epidemiological and pathogenicity researches on avian influenza, arbovirus infection and porcine respiratory diseases etc” ・ Collaboration with Korea on a project entitled“Developing research cooperation in the fields of surveillance, diagnosis and disease control of foot-and-mouth disease, avian influenza, arbovirus infection etc. ・ Collaboration with Korea on a project entitled“Studies on BSE-resistant cattle”. ・ Collaboration with Vietnam on a project entitled “Epidemiologocal and pathogenicity researches on animal influenza.” ・ Collaboration with Korea on a project entitled “Studies on surveillance of wild birds for avian influenza viruses and utilization of the viruses” Collaboration with Vietnam on a project entitled“Swine influenza virus surveillance in Viet Nam” ・ NVAL is working with the Livestock Hygiene Service Centers (LHSC) and Ministry of Agriculture, Forestry and Fisheries (MAFF) to monitor the occurrence of antimicrobial resistance in bacteria in food-producing animals and the consumption of antimicrobials for animal use, and to identify the efficacy of antimicrobials in food-producing animals, to promote prudent use of antimicrobials, and to ascertain the public health problem in Japan. 7. Publication and dissemination of any information within the remit of the mandate given by the OIE that may be useful to Members of the OIE Publication Hayashi,T, Chaichoune,K, Patchimasiri,T, Hiromoto,Y, Kawasaki,Y, Wiriyarat,W, Chakritbudsabong,W, Chaisilp,N, Prayoonwong,N, Parchariyanon,S, Ratanakorn,P, Uchida,Y, Tuda,T, Saito,T, .(2010), Differential host gene responses in mice infected with two highly pathogenic avian influenza viruses of subtype H5N1 isolated from wild birds in Thailand, Virology, in press. Hiromoto,Y, Uchida,Y, Takemae,N, Hayashi,T, Saito,T.(2010). Real-time reverse transcription-PCR assay for differentiating the Pandemic H1N1 2009 influenza virus from swine influenza viruses, Journal of Virological Methods, 170(1-2),169. Iseki,H, Kawai,S, Takahashi,N, Hirai,M, Tanabe,K, Yokoyama,N, Igarashi,I.(2010). Evaluation of a LoopMediated Isothermal Amplification (LAMP) Method as a Diagnostic Tool of Zoonotic Simian malaria parasite Plasmodium knowlesi Infection. Journal of Clinical Microbiology, 48(7), 2509-2514. Iseki,H, Liijia,Z, Kim,C, Inpankeaw,T Sununta,C, Yokoyama,N, Xuan,X, Jittapalap,S, Igarashi,I.(2010 ) . Seroprevalence of Babesia infections of dairy cows in northern Thailand. Veterinary Parasitology 170, 193-196. Konishi,M, Yamamoto,T, Shimada,T, Sentsui,H, Murakami,K.(2010).Development of enzyme-linked immunosorbent assay for detection of antibody against caprine arthritis-encephalitis virus using recombinant protein of the precursor of the major core protein, p55gag. Journal of Veterinary Diagnostic Investigation, 22:415419. 4 Annual reports of OIE Reference Laboratories and Collaborating Centres, 2010 Diagnosis and Control of Animal Disease and Related Veterinary Product Assessment in Asia Nagaoka,K, Yoshioka,M, Shimozaki,N, Yamamura,T, Murayama,Y, Yokoyama,T, Mohri,S.(2010). Sensitive detection of scrapie prion protein in soil. Biochemical and Biophysical Research Communications, 397(3):626-30. National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries. “A Report on the Japanese Veterinary Antimicrobial Resistance Monitoring System-2000 to 2007-.” 2009. Okada H, Iwamaru Y, Imamura M, Masujin K, Mohri S, Yokoyama T.(2010). Immunohistochemical detection of disease-associated prion protein in the intestine of cattle Naturally affected with bovine spongiform encephalopathy by using an alkaline-based chemical antigen retrieval method, Journal of Veterinary Medical Science, 72(11),1423-1429. Tsutsui,T, Kobayashi S, Hayama Y, Nishiguchi A, Kameyama K, Konishi M. Murakami K.(2010). Estimation of within-herd transmission parameter of bovine leukemia virus. Preventive Veterinary Medicine, 95,158-162. Yamamoto,Y.(2011). Asian lineage H5N1 highly pathogenic avian influenza virus replication in feathers of waterfowl. Japanese Journal of Veterinary Research. 59(2). Presentations Aihara,N. 3rd International Symposium on Veterinary Pharmacovigilance. “Post marketing regulation of veterinary medical products in Japan.” Berlin, Germany, December 13, 2010. Akiba,M, Kusumoto,M, Iwata,T.(2010). Rapid identification of Salmonella enterica serovars, Typhimurium, Choleraesuis, Infantis, Hadar, Enteritidis, Dublin, and Gallinarum, by multiplex PCR. 45th US-Japan Cooperative Program in Natural Resources Panel of Animal and Avian Health Meeting. Fukai,K, Morioka,K, Onozato,H, Ohashi,S, Yamazoe,R, Yoshida,K, Sakamoto,K.(2010). The rapid identification of foot-and-mouth disease virus (FMDV) and its serotype by the indirect immunofluorescentantibody test using monoclonal antibodies reacted with the multi-and single-serotype FMDV.Foot and Mouth Disease International Symposium and Workshop Program Book. Hiromoto,Y Takemae,N, Parchariyanon,S, Nguyen,T, D,T,Hoa, L,T,Ngo, N,V,Long, Uchida,Y, Hayashi,T, Kawasaki,Y, Tuda,T, Saito,T.(2010).Swine influenza surveillance in Thailand and neighboring countries Workshop on the Influenza Research of J-GRID. Iwamoto,S. 45th Meeting of the United State-Japan Cooperative Program in Natural Resources Panel of Animal and Avian Health “Post marketing regulation of veterinary medicinal products in Japan - Adverse event reporting system and a summary of national veterinary assay laboratory-reported adverse events in fiscal year 2009.” Ames, Iowa, September 18, 2010. Iwamoto,S. 3rd International Symposium on Veterinary Pharmacovigilance. “Adverse event reporting system and a prospect for international harmonisation” Berlin, Germany, December 13, 2010. Kawai,S, Iseki,H, Takahashi,N, Hirai,M, Tanabe,K, Yokoyama,N, Igarashi,I. ( 2010 ) . A novel molecular diagnostic tool for zoonotic simian malaria parasite Plasmodium knowlesi infection. 2010 XIIth International Congress of Parasitology. Murayama,Y.(2010), Sensitive detection of bovine PrPSc. Prion Japan & Canada. Parchariyanon, S , Ruttanapumma,R, Takemae,N, Hiromoto,Y, V. Jirathanawat, Hayashi,T, Uchida,Y, Saito,T.(2010).The first confirmation of pandemic (H1N1) 2009 virus infection in a pig farm in Thailand. AsianAfrican Research Forum on Emerging and Reemerging Infections. Saito,T, Takemae,N, Uchida,Y, Hiromoto,Y, Hayashi,T.(2010). Evolutional analysis of swine influenza virus in Japan. Negative Strand Viruses. Tsutsui,T, Yamamoto,T.(2010).The foot-and-mouth disease epidemic in Japan, 2010. Open session of the EuFMD standing techinical committee. _______________ Annual reports of OIE Reference Laboratories and Collaborating Centres, 2010 5