Constructing a Pedigree Name____________________________________ Hour ___ Story #1. My name is Steve Thacker. I’m 17 years old. I’d like to tell about an experience I had that taught me some important lessons about genetics. For years, my dad, John Thacker (age 49) has been telling me stories about his family - his father and mother, his two sisters, and his three brothers. Our family moved from his hometown in Virginia to Minnesota when I was only a year old, so I have never really known the people he spoke about. Last summer, I got a chance to learn more about my dad’s side of the family. The Thackers decided to have a family reunion in our old home town of Richmond. Dad could hardly wait to get back and see his family again for the first time in over 15 years. My mother, Marie (age 45) is from the same town, and she was eager to see her own family again, as well as my dad’s. My 12-year-old identical twin sisters, Laura, and Mary, and my 9-year-old brother Tom were also excited about the trip to Virginia. After a two day, 800+ mile trip we drove straight to Grandpa and Grandma Thacker’s house on Pine Street. After a series of introductions to all my cousins, uncles, and aunts (with all that kissing and hugging jazz), I was able to step back and take a better look at my relatives. It was obvious that we were all related. We shared many physical traits in common. Then I noticed Grandpa Thacker’s hands. I thought my Dad had been joking when he used to say that “Gramps” had two little fingers on each hand. But sure enough, it was true. I then checked out Aunt Shirley (age 40), Uncle Pat (age 30), and Uncle Dave (age 47). Again Dad was right. They too have extra little fingers. Aunt Shirley’s daughter, Sue (age 14) does not have the extra digits. Uncle Pat has three girls and a boy. The oldest girl, Maureen (age 15), and her brother, Mike (age 12) have the extra fingers. The middle girls, Amie (age 14) and Anne (age 13) are alright. Uncle Dave and his wife Lucy (age 46 ) have a son, Dan, (age 10) who does not have the extra digits and a daughter, Karen (age 12) who does. Dad’s sister Betty (age 42) and her son, Jim (age 16) do not have a sixth finger. Dad’s other brother Gary (age 43) and his wife Melinda (age 39) and their two daughters, Patty (age 15) and Barbara (age 11) also do not have the sixth finger. Of course, nobody in my immediate family has been affected by this finger variation. Finish the pedigree started below. Include all blood relatives and in-laws (even if not mentioned directly). Show all generations. Use correct genetic symbols and darken in those affected. Also label the 1 st names of all the persons mentioned. Grandpa Grandma I. 1 2 How many cousins does Steve have? ________ Is this condition a dominant or recessive trait? Explain. Which individuals are you sure are carriers?___________________________________________________________________ Who may or may not be carriers? __________________How would you know for sure? _______________________________ Story # 2 Olle and Lena immigrated from Norway to Minnesota in 1875. They farmed wheat and had two healthy, fair-skinned, blondhaired, blue-eyed children - Carl and Anna. Carl married Molly, but they had three miscarriages and were childless. Anna married a strong Swede named Einer and they had three children, Elmer, Hazel, and Harriet. Elmer and Hazel lacked pigment in their hair and skin. They were diagnosed to have albinism.. Elmer and Hazel never married and stayed on the farm to help their aging parents. Harriet left home at 21 and married an olive-skinned, dark, wavy-haired lad named Vitorrio. They had a healthy son, George, who was Olle and Lena’s delight until they both died at ages 98 and 95 respectively. On the back construct this family pedigree and show all generations. Indicate the carriers for albinism and who might be a carrier. Again, be sure to label the persons’ names. Story #2 pedigree here : Story #3 Kathleen (age 32) and Ken (age 31) are married. Kathleen’s mother, Betty (age 60) and Ken’s father, Ed (age 63), are the children of Ted and Agnes, both deceased. Ted and Agnes had two other children, Dorothy (age 65) and James (age 58). Betty’s husband is named Randy (age 61). Ed’s wife, Jennifer, died at the age of 59. Ken has a 34-year-old sister, Marjorie. Kathleen has a 27-year-old sister, named Judy. Kathleen and Ken have three children: Fay (age 8), Kerry (age 6), and Darrell (age 3). Show all generations and label all individuals. Story #4 Finish this story and then construct the pedigree: “Tupac and Shawna were high school sweet-hearts who got married at 18. They had two children within one year. Tupac lost his job pumping gas and became depressed. The young couple had trouble communicating and their relationship ended in a divorce shortly after the birth of their second child. Tupac went back to New York while Shawna left her children with her own mother, Millie, while she went back to finish her GED. While in night school, Shawna….” Pedigree