Partners Research Studies Seeking Volunteers 1. Do You Have Asthma? The Asthma Research Center at Brigham and Women’s Hospital is recruiting asthmatics aged 18 and older for a research study to determine the best strategy for Asthma in the long term. We evaluate three approaches to adjusting the inhaled corticosteroid medications. All study medication will be provided and they are FDA approved. The study involves up to 12 visits over 44 weeks. Compensation is up to $2,075. Call us at 617-732-8201 or 888-99ASTHMA for more information. 2. Seeking recently menopausal healthy women aged 42-58, who have not had a hysterectomy, for hormone research study. The Kronos Early Estrogen Prevention Study (KEEPS) at Brigham and Women's Hospital, Harvard Medical School is conducting research to learn whether Hormone Therapy (HT) has protective effects on the heart and arteries of women who have recently (within 3 years) entered menopause, as well as to better understand the effects of HT on quality of life, memory and thinking. KEEPS participants will undergo health screens at the beginning of the study and will be followed closely during four years of treatment, which will include either a low dose estrogen pill or skin patch plus a natural micronized progesterone capsule or a placebo (contains no active medication) pill, skin patch and capsule. Participants can receive up to $650. Screening tests and parking are at no cost. Individuals who are interested in learning more about the study should call (617) 732-9870 or email bwh@keepstudy.org IRB # 2004-P-002144 3. Prospective Study of cardiac rhabdomyomas in children: An investigation of their natural history and association with Tuberous Sclerosis Complex Do you have a child under the age of 1 that has been diagnosed with a Cardiac Rhabdomyoma? We are currently enrolling patients at the Herscot Center for Tuberous Sclerosis Complex at the Massachusetts General Hospital to undergo genetic testing for Tuberous Sclerosis Complex and to be followed by a pediatric cardiologist, pediatric neurologist, and neuropsychologist. The goal of this research study is to better understand the natural history of cardiac rhabdomyomas in Tuberous Sclerosis Complex and to identify a population of individuals for which we can hopefully improve outcomes through a combination of patient education and close clinical monitoring and follow-up. If your child (or patient) might qualify for participation, please contact or refer patients to: Philippe Major, M.D. at 617-726-0236 or Elizabeth A. Thiele, M.D., Ph.D. at 617-726-0241 Posted 2/6/08 4. Are You 60 or Older? A Native Speaker of English? Right Handed? We Need Your Help! We are seeking research participants for a Non-invasive Study of Brain Activity During Language Tasks. Compensation $15 per hour. Participation takes about 3 hours. Please email zipse@mit.edu or call 617-306-4791. 5. A Study of Brain Activity in People with Posttraumatic Stress Disorder (PTSD) Principal Investigator: Lisa M. Shin, PhD Study: Dr. Lisa Shin and colleagues in the Department of Psychiatry at the Massachusetts General Hospital (MGH) are conducting a research study to examine brain activity in individuals who have posttraumatic stress disorder (PTSD). Participation will take up to 5 hours of your time. It will involve undergoing a psychiatirc assessment, fililng out questionnaires, providing a saliva sample, and lying in a scanner while "pictures" of your brain are taken using functional magnetic resonance imaging (fMRI). Participants will be paid $100 for their time. Who is Eligible: Individuals who are: Age 18-45 Right-handed Not Pregnant Without mental implants, such as pacemakers and aneurysm clips For more information: Please contact Lisa M. Shin, PhD at (617) 726-8120 6. Breast Research Study The Optical Imaging Group in the NMR Center at the Charlestown Navy Yard-Bldg 149 is looking for 21+ year old women to participate in a breast research study. Women must not have breast implants. The study involves optical measurements taken during slight compression. The procedure takes approximately 30 minutes. Remuneration is $25 and a parking sticker. For more information or if interested in participating, please contact Juliette Selb at juliette@nmr.mgh.harvard.edu. 7. Can Salt Affect the Blood Vessels? Brigham and Women’s Hospital is investigating the effect of salt on blood vessel function. We seek healthy men 18-45 years old. This research study will last about 3 weeks and involves a few overnight stays in the hospital, blood sampling, meals, and blood vessel testing. Compensation up to $500. Contact: Ffyona 617-278-0672. 8. Do you want to know how your pregnancy, blood sugar, and heart are related? The Endocrinology, Diabetes, and Hypertension Division of Brigham and Women’s Hospital seeks healthy Black women 18-40 years old who have had normal pregnancies or pregnancies complicated by diabetes in the past 5 years for a research study on diabetes during pregnancy and its effects on heart disease risk. The research study includes an oral glucose tolerance test, fasting blood tests and a non-invasive vascular study. Participants cannot be currently pregnant or nursing. Takes about 5 hours. Stipend is $100. Principal Investigator: Rhonda Bentley-Lewis, MD, MBA, MMSc, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital. If interested, please call Ffyona at 617-278-0672 or e-mail at fpatel1@partners.org. Posted 2/6/08 9. Did you know that Latina women have the highest rate of cervical cancer? Sabes que la mujer latina es la de mas alto porcentaje en cancer cervical? Did you know that cervical cancer is completely preventable? Sabes tambien que es un cancer que se puede prevenir? The Division of Gynecologic Oncology at the Massachusetts General Hospital invites you to participate in a 30-minute survey study aimed at understanding the barriers that limit participation in Pap smear screening programs. La División de Oncología Ginecológica del Hospital de Massachusetts General le invita a participar en una encuesta con la meta de entender las barreras que limitan la participación en programas de Papanicolau. And you can help us! Y usted puede ayudarnos! If you are a Latino woman, age 18-89, and would like to participate in this voluntary survey, please call 617 724-4800 to have this survey mailed to you or visit http://www.surveymonkey.com/s.aspx?sm=fxVkmiJmb68ZmoGJC8jRIQ_3d_3d to complete online. The survey is completely anonymous and confidential. Si usted es una mujer latina, entre 18-89 años de edad, y quisiera tomar parte de esta encuesta, por favor llame al 617 724-4800 o vistahttp://www.surveymonkey.com/s.aspx?sm=9_2fm3uRl70rzTjjwbgqfrEQ_3d_3d para completarlo por internet. La encuesta sera completamente anónimo y confidencial. Posted 2/6/08