University of Bradford Institute of Cancer Therapeutics Award and Teaching Institution: Final Award: Programme Title: Duration: Subject Benchmark statement: Date Produced: University of Bradford MSc (QAA Framework for Higher Education Qualifications at Level M) Cancer Pharmacology Fulltime (1 year) Not applicable 17th February, 2006, amended August 2007 Background Based upon a greater understanding of the molecular aspects of cancer, new opportunities for therapeutic intervention have emerged that are effectively ‘target orientated’. These new therapeutics are quite distinct from the classical chemotherapeutic agents and they offer the prospect of truly selective cancer therapies that are tailored towards the individual patients tumour. This is an exciting time to be involved in cancer therapeutics and cancer pharmacology plays a key role in drug development. In both the laboratory and the clinic, cancer pharmacology has had to adapt to the changing face of drug development by establishing experimental models and target orientated approaches. The MSc course in Cancer Pharmacology will be hosted by the Institute of Cancer Therapeutics which is situated in the heart of the Universities campus in brand new, purpose built facilities. The Institute has a strong research ethos and it is particularly well known as a centre of excellence in Cancer Pharmacology. It is a multidisciplinary organisation incorporating a broad spectrum of skills ranging from chemistry through preclinical studies to early clinical trials. This course is designed to provide the student with a ‘state of the art’ course in modern cancer pharmacology that meets the demand of employers and students at taught post graduate level. For career progression within this sector you require a postgraduate qualification. For pursuit of this type of programme, you will already have a degree qualification, usually from biological, chemistry, medicine, pharmacological or related disciplines. The course promotes advanced scholarship within specialised areas concomitant with the development of key transferable skills (in IT and bioinformatics) and research techniques. The course uses a range of teaching strategies to promote independent study and research to develop a systematic and critical understanding of the molecular basis of cancer and cancer pharmacology, and enhance autonomous learning and personal transferable skills. This course will facilitate development of the skills you require for careers in academia, industry or for further research. Enhancement of your independent learning skills during the course will equip you with the skills to succeed as lifelong learners. A. Programme Aims The programme is intended to: A1 Enable you to develop a systematic understanding and critical awareness of, and skills in, selected disciplines within the field of cancer biology and pharmacology. A2 Develop within the context of cancer pharmacology, a comprehensive understanding of communication, research and scientific method; A3 Provide you with a detailed knowledge of pre-clinical experimental approaches and legislative regulations A4 To provide learning opportunities to enable you to think critically and to further develop as an autonomous and lifelong learner; A5 Further develop your ability in a range of personal and key skills. B. Programme Learning Outcomes On successful completion of the programme you will be able to: B1 Subject Knowledge & Skills B1.1 critically evaluate specialized areas of cancer biology and cancer pharmacology. B1.2 critically evaluate scientific literature and communicate scientific data. B1.3 critically evaluate and appraise experimental laboratory techniques with specific emphasis on obtaining a Home Office personal license for animal studies. B1.4 write and interpret scientific reports. B1.5 write a grant proposal. B1.6 demonstrate self-direction and originality in implementing a research project, employ appropriate experimental approaches and report your findings in relation to current research knowledge and understanding. B2 Core Academic Skills B2.1 demonstrate critical thinking through ability to independently: recognise, define and prioritise problems; analyse, interpret, objectively evaluate and prioritise information, recognising its limitations; B2.2 demonstrate a conceptual understanding of research and scientific method through ability to independently: critically evaluate methodology; critically analyse and interpret data; formulate conclusions based on complete and incomplete data. critically evaluate pre-clinical strategies of drug analysis in vitro and in vivo. critically analyze a therapeutic target and current therapeutic approaches to that specific target. sourcing genetic databases to determine genetic variation in the human and mouse genomes and its influence on pharmacological response. B3 Personal & Key Skills B3.1 C. Develop autonomy in learning and apply skills in; timemanagement, presentation, written communication and problem-solving. The Curriculum The Postgraduate Diploma is studied over two semesters, each comprising of 60 Credits studied as double (20 Credit) and linked (20 Credits spread across two semesters) modules. The Masters programme follows on from this and incorporates an additional 60 Credit research project. The programme is designed as a core curriculum; in both semester 1 and semester 2 you will study units amounting to 40 Credits. A further 40 Credits will be obtained from the linked modules. In semester 1 all units run in parallel whereas in semester 2 there is an intensive training in Experimental Design in the first four weeks of the semester followed by study of the other units in parallel over a 7-week teaching period. D. Teaching, Learning & Assessment Strategies A wide variety of teaching methods appropriate to the learning outcomes of the individual modules are employed throughout the programme, and are supported by Blackboard, the virtual learning environment, provided by the University. A seminar program involving external speakers with International reputations in the field will be established and you will have the chance to discuss specific issues with them in tutorial sessions to be held after the seminar. In addition, the Institute of Cancer Therapeutics has regular internal research seminars and attendance at these is encouraged. The teaching methods focus on student-centred approaches to learning. In this way you will develop the attributes needed for life-long learning and continued professional development. Unit Code CR4001D CR4002D CR4004L BM-9132L Unit Title Semester 1 Molecular Basis of Cancer and Cancer Therapy. Preclinical models for drug evaluation. Critical Appraisal of a Current Topic in the Biomedical Sciences (ICT) Research and Analytical Methods Module Type Credits Level Sem Core 20 M 1 Core 20 M 1 Core 10 (Linked) 10 (Linked) M 1 M 1 20 20 10 (Linked) 10 (Linked) M M M 2 2 2 M 2 60 M N/A Core Semester 2 BM-9133D CR4003D BM-9132L Experimental Design Cancer Pharmacology Research and Analytical Methods Core Core Core BM-9119L Critical Appraisal of a Current Topic in the Biomedical Sciences MSc Research Project (ICT) Core CR4005Z The curriculum may change subject to the university course approval, monitoring and review procedures. Outcome B1.1 will be developed through a series of lectures, workshops and directed study and assessed by unseen written examination questions, critical appraisal, and course work assignments. Outcome B1.2 will be developed and assessed by course work. Acquisition of outcomes B1.3-1.6 will occur gradually and cumulatively through a number of modules employing a mix of lectures, laboratory investigations, coursework, workshops, individual project work and directed private study. They will be assessed by unseen written examination using constructed-response (essay) type questions, course work, grant proposal, assignments, oral presentation, dissertation and project work. Directed private study will involve you in a variety of activities, which include directed reading of selected textbooks and specified source literature, Blackboard (directed Web-based materials), report writing and other assignments. The development of outcomes B2.1 and B2.2 will be through involvement in small-group seminars, Journal Clubs, laboratory investigations and individual project-based work and assessed by critical appraisal, course work, seminar paper, written assignment, oral presentation and project work. Key skills are embedded in the curriculum and some modules develop or consolidate and assess one or more of the key skills listed in outcome B3.1. More detailed description of the way that learning is related to assessment in the modules that make up this programme can be found on the module descriptors. E. Admission requirements Up to 30 students can be admitted onto the Masters programme in Cancer Pharmacology, and this includes a significant number of applicants from outside the EU. Offers are made following detailed consideration of each individual application. Most important in the decision to offer a place is our assessment of a candidate’s potential to benefit from their studies and of their ability to succeed on this particular course. Entrance requirements will vary, but are set after consideration of each applicant’s academic background and achievements and all other relevant experience. As a general guideline, acceptance on the Masters programme requires an Honours degree in a related scientific discipline or equivalent. The expectation is that this would be at 2.2 classification or above. Applicants whose first language is not English will need to demonstrate proficiency in English in accordance with University Regulations. For example, in the International English Language Testing Service test (IELTS) you need to achieve an overall band of at least 6 with 5 in each of the four sub-tests. The Test of English as a Foreign Language (TOEFL) administered by the Educational Testing Service, Princeton, New Jersey, 08540, USA. You will need to score at least 550 on the paper-based test, 220 on the computer-based test and 83 on the internet-based test. For further details, see http://www.brad.ac.uk/international/english.php. Students with prior learning or prior experimental learning may be accredited on a case by case basis by a claim for APL or APEL. F. Assessment regulations To be eligible for the award of Postgraduate Diploma in Cancer Pharmacology you must attain at least 40% in individual units amounting to 100 Credits and at least 35% in individual units amounting to the other 20 credits. To be eligible for the award of Masters in Cancer Pharmacology you must attain at least 40% in individual units amounting to 160 Credits (including a 60 Credit Research Project) at least 35% in individual units amounting to 20 credits. If you obtain an overall weighted average of at least 70% at the first attempt, including a mark of over 70% in the 60 Credit project at first attempt you will be awarded a Masters degree with Distinction. If you obtain an overall weighted average of at least 60% at the first attempt, including a mark of over 60% in the 60 Credit project at first attempt will be awarded a Masters degree with Merit. The full assessment regulations covering postgraduate courses are available on the University website. G. Student Support & Guidance The Institute of Cancer Therapeutics will integrate the established practices of the Department of Biomedical Sciences that has a good reputation in this area with students on the Masters programme being supported by both a dedicated Course Tutor through fortnightly meetings with the cohort of students and allocated individual personal tutorial support. Regular Staff Student Liaison meetings inform the course team of student views and Academic Committee meetings have student representation. Student academic support also is provided by individual tutors / supervisors for the Critical Appraisal and Research Project through regular meetings for the duration of these activities. Formalised formative feedback is given on drafts of these elements prior to submission. Departmental support is enhanced by University Learning Support Services that includes Library and Computing services, a Careers Service and a Disabilities Office. H. Further Information Further information can be obtained from the Postgraduate Admissions Tutor, Institute of Cancer Therapeutics, University of Bradford (www.cancer.brad.ac.uk).