Mitosis lecture MGY425
Spindle Assembly
Wadsworth P, Khodjakov A. E pluribus unum: towards a universal mechanism for spindle assembly.
Trends Cell Biol. 2004 14:413-9.
O'Connell CB, Khodjakov AL. Cooperative mechanisms of mitotic spindle formation.
J Cell Sci. 2007 120:1717-22.
Walczak CE, Heald R.
Mechanisms of mitotic spindle assembly and function.
Int Rev Cytol. 2008;265:111-58.
Gadde and Heald
Curr Biol 2004, 14:R797-R805
Ducat D, Zheng Y. Aurora kinases in spindle assembly and chromosome segregation.
Exp Cell Res. 2004 301:60-7
Cheeseman IM, Desai A. Molecular architecture of the kinetochore-microtubule interface.
Nat Rev Mol Cell Biol. 2008 9:33-46.
Westermann S, Drubin DG, Barnes G. Structures and functions of yeast kinetochore complexes.
Annu Rev Biochem. 2007;76:563-9
Davis TN, Wordeman L. Rings, bracelets, sleeves, and chevrons: new structures of kinetochore proteins.
Trends Cell Biol. 2007 17:377-82.
Chan et al Kinetochore structure and function. Trends Cell Biol. 2005 15:589-98
D. Cimini.
Merotelic kinetochore orientation, aneuploidy and cancer.
BBA (2008) 1786:32-40
Alexander E Kelly and Hironori Funabiki
Correcting aberrant kinetochore microtubule attachments: an
Aurora B-centric view. Curr. OP. Cell Biol. (2009) 21:1-8
Cimini D. Detection and correction of merotelic kinetochore orientation by Aurora B and its partners. Cell
Cycle. 2007 Jul 6:1558-64.
Rieder CL. Kinetochore fiber formation in animal somatic cells: dueling mechanisms come to a draw.
Chromosoma. 2005 114:310-8
Kinetochore orientation in Mitosis and Meiosis Cell 2004 119:317-327
Captivating Capture: How microtubules attach to kinetochore Curr. Biol 2003 13:R449-R460
Cimini D, Degrassi F. Aneuploidy: a matter of bad connections. Trends Cell Biol. 2005 15:442-51
Kapoor et al Chromosomes can congress to the metaphase plate before bi-orientation. Science. 2006 311:388-91
Role of Ran
Clarke PR, Zhang C. Spatial and temporal coordination of mitosis by Ran GTPase.
Nat Rev Mol Cell Biol. 2008 Jun;9:464-77
Goodman and Zheng Mitotic spindle morphogenesis:Ran on the MT cytoskeleton and beyond 2006
Biochemical Society Transactions vol 34 part 5 page 716
Bastiens et al Gradients in the self-organization of the mitotic spindle. Trends in Cell Biol. 2006 61:125-134
Kalab P, et al.Analysis of a RanGTP-regulated gradient in mitotic somatic cells. Nature. 2006 440:697-70
Spindle positioning
Cowan CR, Hyman AA. Asymmetric cell division in C. elegans: cortical polarity and spindle positioning.
Annu Rev Cell Dev Biol. 2004;20:427-53
Gönczy P, Rose LS. Asymmetric cell division and axis formation in the embryo. WormBook. 2005 Oct 15;:120.
Lechler T, Fuchs E. Asymmetric cell divisions promote stratification and differentiation of mammalian skin
.Nature. 2005 437:275-80.
Spindle Checkpoint
K. M. May and K. G.Hardwick The spindle checkpoint J. Cell Science 2006 119, 4139-4142
Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time.
Nat Rev Mol Cell Biol. 2007 8:379-93
Malmanche N, Maia A, Sunkel CE. The spindle assembly checkpoint: preventing chromosome mis-segregation
during mitosis and meiosis. FEBS Lett. 2006 580:2888-95
Pinsky BA, Biggins S The spindle checkpoint: tension versus attachment. Trends Cell Biol. 2005 15:486-9
Taylor et al
Chromosome Research 2004 12:599-616
Kops et al On the road to cancer: aneuploidy and the mitotic checkpoint. Nat Rev Cancer. 2005 5:773-85
Spindle matrix
Johansen KM, Johansen J. Cell and molecular biology of the spindle matrix. Int Rev Cytol. 2007;263:155-206.
Zheng Y, Tsai MY. The mitotic spindle matrix: a fibro-membranous lamin connection. Cell Cycle. 2006
Microtubule FLUX
Kwok BH, Kapoor TM. Microtubule flux: drivers wanted. Curr Opin Cell Biol. 2007 19:36-42
Sharp DJ, Mennella V, Buster DW. KLP10A and KLP59C: the dynamic duo of microtubule depolymerization.
Cell Cycle. 2005 4:1482-5.
Zhang D, Rogers GC, Buster DW, Sharp DJ. Three microtubule severing enzymes contribute to the "Pacmanflux" machinery that moves chromosomes.
J Cell Biol. 2007 177:231-42.
See Trends in Cell Biology series during 2005
Eggert et al 2006 Ann Rev Biochem 75: 543-566
Annu. Rev. Cell Dev. Biol. 2001. 17:351–86
Balasubramanian et al Curr Biol
2004, 14:R806-818
Cleavage furrow
Burgess, Site selection for the cleavage furrow at cytokinesis 2005 Trends in Cell Biol. 15:156-162
Matsumura, Regulation of myosin II during cytokinesis in higher eukaryotes Trends in Cell Biol 15:371-377
Wu et al J Cell Biol. 174:391-402 2006
Bement et al 2006 Bioessays 28:983-993 RhoGTPase activity zones and transient contractile arrays
Narumiya 2006 Curr. Op. Cell Biol. 18:199-205 RhoGTPases in animal cell mitosis
D’Avino 2005 J. Cell Science 118:1549-1558 Cleavage furrow formation and ingression during animal
cytokinesis: a microtubule legacy
Bringmann Nature. 2005 436:731-4. A cytokinesis furrow is positioned by two consecutive signals.
Motegi et al Two phases of astral microtubule activity during cytokinesis in C. elegans embryos. Dev Cell. 2006
Spiliotis 2006 J. Cell Science 119:4-10 Here come the septin: novel polymers that coordinate intracellular
function and organization
Force generation
Robinson and Spudich
Curr Op Cell Biol 2004, 16:182-188
Wang, Mechanism of cortical ingression during early cytokinesis: thinking beyond the contractile ring
hypothesis Trends in Cell Biol. 2005 15:581-589
Membrane trafficking
Strickland and Burgess
Trends in Cell Biology
Albertson, Membrane traffic: a driving force in cytokinesis 2005 Trends in Cell Biol. 15:92-101
Janetopoulos 2006 J. Cell Biol 174:485-90 Phosphoinositide signaling plays a key role in cytokinesis.