CURRICULUM VTAE Personal: Dr Fazal Subhan Professor of Pharmacy, Department of Pharmacy, University of Peshawar, Peshawar, N.W.F.P. Pakistan. Date of Birth: 14th of April, 1959. Place of Birth: Swat, Khyber Pukhtunkhwa, Pakistan. Pone # Office: Residence: Mobile: Email: 091-9216750 092-5704834 03018805966 fazal_subhan@upesh.edu.pk fsubhan2000@yahoo.com Education: Institute Welsh School of Pharmacy, Division of Pharmacology, Cardiff University of Wales, UK. Faculty of Pharmacy, Department of Pharmacology, University of the Punjab, Lahore, Pakistan. Faculty of Pharmacy, Department of Pharmacology, University of the Punjab, Lahore, Pakistan. Faculty of Pharmacy, Gomal university, D.I.Khan, Pakistan. Degree Period Subject of Study Ph.D. 1996-2000. Pharmacy/Pharmacology M.Phil. 1991-1992. Pharmacy/Pharmacology M.Pharmacy 1984-1985. Pharmacy/Pharmacology B-Pharmacy Pharmacy 1980-1984. PhD thesis title: Neurotransmitter systems and drug dependence mechanisms. M.Pharm thesis title: Biological half life and biotransformation of N-methylisatin-3thiosemicarbazone. 1 Special training: Successfully completed courses related to animal handling and experimentation (Module 1, 2, 3 and 4) organised by the institute of Biology, University of Wales, Cardiff, UK. Personal animal licence holder authorised to perform experiments on animals including Rats, Mice, Guinea pigs and Rabbits in UK. Teaching experience: Employer Department of Pharmacy, University of Peshawar, Pakistan. Department of Pharmacy, University of Peshawar, Pakistan. Department of Pharmacy, University of Peshawar, Pakistan. Faculty of Pharmacy, Gomal University, D.I.Khan. Position Duration Job description Professor March 21, 2009 to-date Professor Teaching and research June 30, 2003 March 20, 2009. Oct 8, 1987 to June 29, 2003. Oct 1, 1986 to Oct 7, 1987. Teaching and research in the field of Pharmacy/Pharmacology Teaching and research in the field of Pharmacy/Pharmacology Teaching the subjects of Physiology and Pharmacology Associate Professor Lecturer Lecturer Administrative Experience: Successfully completed three years term as chairman of Department of Pharmacy University of Peshawar- (27-08-2008 to 26-08-2011) Distinctions/ Memberships: First Class First Position in Master of Pharmacy (Pharmacology). COT Scholarship for Ph.D. studies abroad. Overseas Research Scholarship (ORS) award for the Year 1997&98 (U.K Higher Education Research Award for Overseas Students). Higher Education Commission (HEC) of Pakistan recognised supervisor in the field of Pharmacy/Pharmacology Member of the drug court. Member of the National Pharmacy Curriculum Committee. Member of Ethical committee of Department of Pharmacy, UoP. Member of Board of studies of: 2 University College of Pharmacy, University of the Punjab, Lahore. KMU Institute of Basic Medical Sciences. Faculty of Pharmacy, Gomal university, D.I. Khan Department of Pharmacy, KUST. Department of Pharmacy, Malakand University, Chakdara. Department of Pharmacy, COMSATS. Presentation in international conferences during Ph.D. studies: British Pharmaceutical Conference held in September 1999 at Cardiff, UK. British Pharmaceutical Conference held in September 1998 at Eastbourn, UK. BAP/CCNP Conference held in July 1997 at Cambridge, UK. Current engagements: Teaching the subject of Pharmacology to the second and third professional B-Pharmacy students. Supervising and teaching to M.Phil./Ph.D. Scholars in field of basic and clinical Pharmacology. Research project completed/in-progress: 1. Pharmacological investigation on some indigenous plants/ Hypericum perforatum, potentially useful for depression, pain and addiction (completed). 2. Studies on selective serotonin reuptake inhibitor (SSRI) fluoxetine in the management of opioid (heroin) dependence and analgesia (completed). 3. Biopharmaceutical profile of Risperidone (completed) 4. Effect of fasting on serum lithium in preclinical and clinical models (completed) 5. Effect of Bacopa monnieri on morphine dependence and tolerance to analgesia in animal models (completed). 6. Evaluation of some selected medicinal plants and their combinations in cisplatin induced vomiting in vomit model(s); behavioral neurochemical correlates (completed). 7. Effects of selected medicinal plants combination on hypertension, dyslipidemia and depression (in progress). 8. Evaluation of antidepressants on bacterial resistance to antibiotics.(completed) 3 9. Development and comparative clinical safety and effectiveness evaluation of controlled release tablets vs. conventional tablets of olanzapine & prochlorperazine (completed) 10. Preclinical evaluation of selected synthetic bioisosteric nitrogen containing salicyl alcohol derivatives in inflammation, ulcergeninicity and pain modalities (completed). 11. Hepatotoxicity and nephrotoxicity of morphine and illicit street heroin and its amelioration by extract of Bacopa monniera (completed). 12. Comparative evaluation of selected antioxidants and their combination in cisplatin induced vomiting in pigeons (completed). Research grants: S# Research Project name 1 Higher Education commission grant for the maintenance Pharmacological Investigation on some indigenous plants/Hypericum perforatum, potentially useful for depression, pain and addiction Selected Serotnin Re-uptake Inhibitor (SSRI), fluxetine, drug dependence and analgesia Biopharmaceutical profile of Risperidone Effects of Selected Medicinal Plants combination on Hypertension, Dyslipidemia and Depression Evaluation of antidepressants on Bacterial resistance to antibiotics 2 3 4 5 6 Total Research grant Rs. 10,00000/- Source Remarks HEC granted Completed Rs. 40,000/- University of Peshawar granted Completed Rs. 1,80,000/- University of Peshawar granted Completed Rs. 4,95,000/- University of Peshawar granted University of Peshawar granted Completed Rs. 2,76,500/- Rs. 4,62,648/- University of Peshawar granted In progress completed Research students: M.Phil. Ph.D. M.Phil. Ph.D. 8 5 5 3 Completed Completed (in progress) (in progress) 4 List of Publications: 1. Gowhar Ali, Fazal Subhan, Muzaffar Abbas, Jehan Zeb, Muhammad Shahid, Robert DE Sewell. A streptozotocin-induced diabetic neuropathic pain model for static or dynamic mechanical allodynia and vulvodynia: validation using topical and systemic gabapentin. Naunyn-Schmiedeberg's Archives of Pharmacology (2015) DOI: 10.1007/s00210-015-1145-y. 2. Rehmat Shah, Fazal Subhan, Gowhar Ali, Ihsan Ullah, Sami Ullah, Muhammad Shahid, Nisar Ahmad, Khwaja Fawad. Olanzapine induced biochemical and histopathological changes after its chronic administration in rats. Saudi Pharmaceutical Journal (2015), DOI:10.1016/j.jsps.2015.06.006. 3. Muhammad Ayaz, Fazal Subhan, Jawad Ahmed, Arif-ullah Khan, Farhat Ullah, Ihan Ullah, Gowhar Ali, Sajid Hussain. Sertraline enhances the activity of antimicrobial agents against pathogens of clinical relevance. Journal of Biological ResearchThessaloniki (2015) 22:4. 4. Muhammad Ayaz, Muhammad Junaid, Fazal Subhan, Farhat Ullah, Abdul Sadiq, Sajjad Ahmad, Muhammad Imran, Zul Kamal, Sajid Hussain, Syed Majid Shah. Heavy metals analysis, phytochemical, phytotoxic and anthelmintic investigations of crude methanolic extract, subsequent fractions and crude saponins from Polygonum hydropiper L. BMC Complementary and Alternative Medicine (2014) 14:465. 5. Ihsan Ullah, Fazal Subhan, John A Rudd, Khalid Rauf, Javaid Alam, Muhammad Shahid, RD Sewell. Attenuation of cisplatin-induced emetogenesis by standardized Bacopa monnieri extracts in the pigeon: Behavioral and neurochemical correlations. Planta Medica (2014) 80:1569-1579. 6. Gowhar Ali, Fazal Subhan, Nazar Islam, Ul, Ikhtiar Khan, Khalid Rauf, Sami Ullah, Muzaffar Abbas, Abdur Rauf. Input of Isosteric and Bioisosteric Approach in Drug Design. Journal of the Chemical Society of Pakistan (2014) 36:150-169. 7. Muhammad Shahid, Fazal Subhan. Comparative histopathology of acetaminophen induced hepatotoxicity in animal models of mice and rats. Pharmacologyonline (2014) 3:32-43. 8. Muhammad Shahid, Fazal Subhan. Protective effect of Bacopa monniera methanol extract against carbon tetrachloride induced hepatotoxicity and nephrotoxicity. Pharmacologyonline (2014) 2:18-28. 9. Waqar Ahmad, Imran Khan, Mir Azam Khan, Manzoor Ahmad, Fazal Subhan, Nasiara Karim. Evaluation of antidiabetic and antihyperlipidemicactivity of Artemisia indica linn (aeriel parts) in Streptozotocin induced diabetic rats. Journal of Ethnopharmacology 151 (2014) 618–623. 10. Zia Ahmed, Fazal Subhan, Muhammad Tahir Shah and Saeed Farooq. Effect of fasting on serum lithium levels: An experimental study in animal models. Pakistan Journal of Pharmaceutical Sciences. (2014), 27, 33-37. 5 11. Sami Ullah, Fazal Subhan, Syed Muhammad Sultan, Amir Badshah, Aziz Muhammad, Khalid Rauf, Gowhar Ali. Development, in Vitro Characterization and Comparative Pharmacokinetic Evaluation of Novel Controlled Release Matrix Tablets vs. Conventional Tablets of Olanzapine in Healthy Human Volunteers. Journal of the Chemical Society of Pakistan (2013) 35:947-954. 12. Nasir Ullah, Nazar Ul Islam, Gowhar Ali, Fazal Subhan, Ikhtiar Khan. Bioisosteric synthesis of nitrogen containing derivatives of salicyl alcohol, their in vivo pharmacological studies with molecular modeling. Medicinal Chemistry Research (2013) 22:4677–4684. 13. Khalid Rauf, Fazal Subhan, AM Al-Othman, I Khan, A Zarrelli, MR Shah. Preclinical Profile of Bacopasides From Bacopa monnieri (BM) As An Emerging Class of Therapeutics for Management of Chronic Pains. Current medicinal chemistry (2013) 20:1028-1037. 14. Khalid Rauf, Fazal Subhan, Muzaffar Abbas, Syed Mobasher Ali, Gowhar Ali, Muhammad Ashfaq, Ghulam Abbas. Inhibitory Effect of Bacopasides on Spontaneous Morphine Withdrawal Induced Depression in Mice. Phytotherapy Research (2013). 15. Khalid Rauf, Fazal Subhan, Ghulam Abbas, Gowhar Ali, Syed Mobasher Ali Abid, Usman Arshad, Muhammad Junaid Hassan Sharif. Bacopa monnieri inhibits locomotor hyperactivity induced by morphine without altering noradrenaline. Pharmacologyonline (2013) 1:172-181. 16. Munasib Khan, Fazal Subhan, Arif-ullah Khan, Muzaffar Abbas, Gowhar Ali, Khalid Rauf, Anwarul Hassan Gilani. Nature cures nature: Hypericum perforatum attenuates physical withdrawal signs in opium dependent rats. Pharmaceutical Biology (2013):15. 17. Gowhar Ali, Fazal Subhan, Abdul Wadood, Ajmal Khan, Nasir Ullah, Nazar Ul Islam, Ikhtiar Khan. Pharmacological evaluation, molecular docking and dynamics simulation studies of salicyl alcohol nitrogen containing derivatives. African Journal of Pharmacy and Pharmacology (2013) 7:585-596. 18. Gowhar Ali, Fazal Subhan, Nazar Ul Islam, Nasir Ullah, Muhammad Shahid, Sami Ullah, Ihsan Ullah, Rehmat Shah, Ikhtiar Khan, Robert DE Sewell, Ghulam Abbas. Comparative evaluation of gastroulcerogenic potential of nitrogen isoforms of salicyl alcohol and aspirin in rats: biochemical and histological study. Archives of Pharmacal Research (2013):1-11. 19. Gowhar Ali, Fazal Subhan, Nazar Ul Islam, Nasir Ullah, Robert D. E Sewell, Muhammad Shahid, Ikhtiar Khan. Synthetically modified bioisosteres of salicyl alcohol and their gastroulcerogenic assessment versus aspirin: biochemical and histological correlates. Naunyn-Schmiedeberg's Archives of Pharmacology (2013):1-10. 20. Gowhar Ali, Fazal Subhan, Nazar Ul Islam, Inamullah Khan, Khalid Rauf, Sami Ullah, Muzaffar Abbas, Abdur Rauf. Input of Isosteric and Bioisosteric Approach in Drug Design. Journal of the Chemical Society of Pakistan (2013). 6 21. Amir Badshah, Fazal Subhan, NH Shah, NI Bukhari, M Saeed, KU Shah. Once daily controlled release matrix tablet of Prochlorperazine maleate: influence of Ethocel® and/or Methocel® on in vitro drug release and bioavailability. Drug Development and Industrial Pharmacy (2012 ) 38:190-199. 22. Ihsan Ullah, Fazal Subhan, Khalid Rauf, Amir Badshah, Gowhar Ali. Role of gastrointestinal motility/gastric emptying in cisplatin-induced vomiting in pigeon. African Journal of Pharmacy and Pharmacology (2012) 6:2592-2599. 23. Rehmat Shah, Fazal Subhan, Khalid Rauf, Sami Ullah, Gowhar Ali. Case report study of urea cycle disorder from North-west part of Pakistan. Pharmacologyonline (2012) 1:1-5. 24. Khalid Rauf, Fazal Subhan, Muzaffar Abbas, Ikram ul Haq, Gowhar Ali, Muhammad Ayaz. Effect of acute and sub chronic use of Bacopa monnieri on dopamine and serotonin turnover in mice whole brain. African Journal of Pharmacy and Pharmacology (2012) 6:2767-2774. 25. Khalid Rauf, Fazal Subhan, R.D.E. Sewell. A bacoside containing Bacopa monnieri extract reduces both morphine hyperactivity plus the elevated striatal dopamine and serotonin turnover. Phytotherapy Research (2012) 26:758-763. 26. Khalid Rauf, Fazal Subhan, Muzaffar Abbas, Amir Badshah, Ihsan Ullah, Sami Ullah. Effect of bacopasides on acquisition and expression of morphine tolerance. Phytomedicine (2011) 18:836-842. 27. Zahid Nazar, Javaid Akhtar, Saeed Farooq, Muhammad Irfan, Rubina Shaheen, Muneer Ahmad, Naila Riaz Awan, Zia Ahmad, Fazal Subhan, Athar Mahmood Safi. Adverse side effects of lithium and fasting (Ramadan). Journal of Postgraduate Medical Institute (Peshawar-Pakistan) (2011) 23. 28. Arif-ullah Khan, Anwarul-Hassan Gilani, Munasib Khan, Fazal Subhan. Pharmacological explanation for medicinal use of St. John's wort in the hypo-motility disorder of gut. Latin American Journal of Pharmacy (2011) 580-583. 29. Amir Badshah, Fazal Subhan, Khalid Rauf, Nadeem Irfan Bukhari, Kifayatullah Shah, Samiullah Khan, Zia Ahmed, Ihsanullah Khan. Development of controlled-release matrix tablet of risperidone: influence of methocel®-and ethocel®-based novel polymeric blend on in vitro drug release and bioavailability. AAPS PharmSciTech (2011) 12:525-533. 30. Muzaffar Abbas, Fazal Subhan, Khalid Rauf, Munasib Khan, Syed Nadeem-ulHassan Mohani. The involvement of biogenic amines in the antidepressant effect of Bacopa monnieri. Pharmacologyonline (2011) 1:112-123. 31. Muzaffar Abbas, Fazal Subhan, N. Mohani, Khalid Rauf, G. Ali, M. Khan. The involvement of opioidergic mechanisms in the activity of Bacopa monnieri extract and its toxicological studies. African Journal of Pharmacy and Pharmacology (2011) 5:1120-1124. 7 32. Fazal Subhan, Nasiara Karim, Anwarul Hassan Gilani, Robert DE Sewell. Terpenoid content of Valeriana wallichii extracts and antidepressant‐like response profiles. Phytotherapy Research (2010) 24:686-691. 33. Fazal Subhan, Muzaffar Abbas, Khalid Rauf, Abdul Baseer. Anti GIT motility, toxicological and phytochemical studies on Bacopa monnieri. Pharmacologyonline (2010) 3:937-950. 34. Fazal Subhan, Muzaffar Abbas, Khalid Rauf, Mohammad Arfan, Robert DE Sewell, Gowhar Ali. The role of opioidergic mechanism in the activity of Bacopa monnieri extract against tonic and acute phasic pain modalities. Pharmacologyonline (2010) 3:903-914. 35. Arifullah Khan, Munasib Khan, Fazal Subhan, Anwarul Hassan Gilani. Antispasmodic, bronchodilator and blood pressure lowering properties of Hypericum oblongifolium–possible mechanism of action. Phytotherapy Research (2010) 24:10271032. 36. Saeed Farooq, Zahid Nazar, Javed Akhter, Mohammad Irafn, Fazal Subhan, Zia Ahmed, Ijaz Hassan Khatak, Farooq Naeem. Effect of fasting during Ramadan on serum lithium level and mental state in bipolar affective disorder. International Clinical Psychopharmacology (2010) 25:323-327. 37. Amir Badshah, Fazal Subhan, Khalid Rauf. Controlled release matrix tablets of olanzapine: influence of polymers on the in vitro release and bioavailability. AAPS PharmSciTech (2010) 11:1397-1404. 38. Fazal Subhan, Nematullah Khan, R.D.E Sewell. Adulterant profile of illicit street heroin and reduction of its precipitated physical dependence withdrawal syndrome by extracts of St John's wort (Hypericum perforatum). Phytotherapy Research (2009) 23:564-571. 39. Fazal Subhan. Anti-inflammatory activity of methanolic and aqueous extracts of Valeriana wallichii rhizome. Presented at the 1st National symposium, old plants, new remedies (2008) Department of Pharmacy, University of Malakand. 40. Fazal Subhan. Antidepressant and phytochemical studies on Bacopa monniera. Presented at the 1st National symposium, old plants, new remedies, (2008) Department of Pharmacy, University of Malakand. 41. Fazal Subhan. Effect of Hydroethanolic extracts of Hypericum perforatum on Naloxone induced opium withdrawal syndrome in rats. Presented at the 1st National symposium, old plants, new remedies, (2008) Department of Pharmacy, University of Malakand. 42. Fazal Subhan, Munasib Khan, Mohammad Ibrar, Arifullah Khan, AH Gilani. Antagonism of antinociceptive effect of hydro-ethanolic extract of Hypericum perforatum Linn. by a non selective opioid receptor antagonist, naloxone. Pakistan Journal of Biological Sciences (2007) 10:792. 8 43. Fazal Subhan, Nasiara Karim, Muhammad Ibrar. Antiinflammatory activity of methanolic and aqueous extracts of Valeriana wallichii DC rhizome. Pak J Plant Sci (2007) 13:103-108. 44. Mohammad Ibrar, Fazal Subhan, Farrukh Hussain. Post Harvest Treatment of Medicinal Plants using simple facilities. Peshawar University Teacher Association Journal (2005) 12:59-66. 45. Anwar H Gilani, Arif-ullah Khan, Qaiser Jabeen, Fazal Subhan, Rukhsana Ghafar. Antispasmodic and blood pressure lowering effects of Valeriana wallichii are mediated through K+ channel activation. Journal of Ethnopharmacology (2005) 100:347-352. 46. Anwarul Hassan Gilani, Arifullah Khan, Fazal Subhan, Munasib Khan. Antispasmodic and bronchodilator activities of St John's wort are putatively mediated through dual inhibition of calcium influx and phosphodiesterase. Fundamental and Clinical Pharmacology (2005) 19:695-705. 47. Fazal Subhan, Munasib Khan, Ibrar. Mohammad, Nazar Ul Islam, Anwarul Hassan Gilani, Arifullah Khan. Effect of Aqueous–Ethanolic extract of Hypericum perforatum on naloxone precipitated opium withdrawal syndrome. Presented at the 2nd International conference on traditional medicine & Materia Medica, (2004) Tehran, Iran. 48. Mohammad Ibrar, Fazal Subhan, Amir Zada Khan. Medicinal plants cultivation, collection and preservation. Peshawar University Teacher Association Journal (2003) 10:49-56. 49. Fazal Subhan, A Rasheed, R.D.E Sewell. Selective CCK2 receptor antagonist, CI 988 failed to enhance the reinforcing properties of morphine as assessed by drug discrimination paradigm in rats. Pakistan Journal of Pharmacy (2002):(11-15), 11-17. 50. Fazal Subhan, Abdul Matin Khan, Ahmad Yar Sial, Muhammad Azam Zia, Haroon ur Rashid. Drug dependence-neurotransmitter systems and paradigm for assessment. Pakistan Armed forces Medical Journal (2002) 52:76-83. 51. Fazal Subhan, Amir Zada Khan, Mohammad Saeed, I Khan. Effect of chronic treatment of antidepressants on dopamine and its metabolites in the brain areas of nucleus accumbens and striatum: An animal study. Scientific Khyber (2002) 15. 52. Fazal Subhan, Mohammad Ibrar, Amir Zada Khan, M Arfan, G Nawab. Effect of Ajuga bracteosa on serum level of triiodothyronin (T3) and thyroxin (T4) in rabbits. Journal of Science and Technology (2002) 26:7-9. 53. Fazal Subhan. Rewarding properties of serotonin selective reuptake inhibitor, paroxetine: Behavioural and biochemical correlates. Peshawar University Teacher Association Journal (2002) 9:27-33. 54. Ikhtiar Khan, Gul Nawab, Ijaz Ahmad, Fazal Subhan. Thyroid hormones level in healthy population of N.W.F.P. Scientific Khyber (2002) 15:9-16. 9 55. Abdul Subhan Ijaz, Fazal Subhan, Nazar ul Islam, Saeed Ahmad, Arif Ali Rajer. Synthesis of pharmacologically active isatin derivatives. Scientific Khyber (2002) 15:916. 56. Fazal Subhan, David M Pache, Robert DE Sewell. CCKb receptor antagonism attenuates negative motivational properties and somatic physical signs of morphine withdrawal. Pharmacology Reviews and Communications (2000) 11:27-37. 57. Fazal Subhan, David M Pache, Robert DE Sewell. Potentiation of opioid-induced conditioned place preference by the selective serotonin reuptake inhibitor fluoxetine. European Journal of Pharmacology (2000) 390:137-143. 58. Fazal Subhan, Paul N Deslandes, David M Pache, Robert DE Sewell. Do antidepressants affect motivation in conditioned place preference? European Journal of Pharmacology (2000) 408:257-263. 59. Muhammaad Saeed, Anwar ul Hassan Gilani, Zafar Iqbal, Fazal Subhan, Jamshid Ali Khan. Screening of some 4-acetyl-4-phenylpiprridine derivatives for their effects on blood pressure and smooth muscle contraction. Scientific Khyber (2000) 13:59-62. 60. Daniel M Hutcheson, Fazal Subhan, David M Pache, Rafael Maldonado, MarieClaudé Fournié-Zaluski, Bernard P Roques, Robert DE Sewell. Analgesic doses of the enkephalin degrading enzyme inhibitor RB 120 do not have discriminative stimulus properties. European Journal of Pharmacology (2000) 401:197-204. 61. Fazal Subhan, D.M Pache, P.S.J Spencer, R.D.E Sewell. Effect of the selective serotonin reuptake inhibitor, fluoxetine, on the rewarding properties of opioids as assessed by conditioned place preference. Journal of Pharmacy and Pharmacology (1999) 51:(Supp) 14. 62. Fazal Subhan, DM Pache, RDE Sewell. CCKB receptor antagonism attenuates naloxone‐induced morphine withdrawal conditioned place aversion and escape behaviour. Journal of Pharmacy and Pharmacology (1998) 50:205-205. 63. Fazal Subhan, Nazar ul Islam, Azmath Rasheed, Abdul Subhan Ijaz, Mehboob Alam. Biochemical and histological effects induced by the antiviral drug, N-methylisatin-3thio semicarbazone in rabbits. Journal of Science and Technology University of Peshawar (1998) 22:17-21. 64. Fazal Subhan, R.D.E. Sewell. Effect of rewarding doses of morphine or fluoxetine on the striatal and nucleus accumbens levels of dopamine and its metabolites: A comparative study. Pakistan Journal of Pharmacy (1997) 10:23-34. 65. Fazal Subhan, D.M Hutcheson, D.M Pache, R.D.E Sewell. RB 1000 and the CCKB antagonist, CI 988 fail to affect a morphine interoceptive cue. Psychopharmacology (1997):(Supp) 11, 13. 66. Fazal Subhan, Azmat Rasheed, Mohammad Arfan. Effect of Ajuga bracteosa on some of the biochemical parameters in rabbits. Hamdard Medicus (1996) XXXIX:84-89. 10 67. A Rasheed, M Riaz, Fazal Subhan, S Javid. Blood glucose level and body temperature after concomitant administration of chloramphenicol and aspirin in rabbits. Pakistan Journal of Zoology (1992) 24:360-362. 68. A Rasheed, M Alam, Fazal Subhan. Pharmacokinetics of N-methylisatin-3thiosemicarbazone in rabbit. Pakistan Veterinary Journal (1987) 7. 11