ENDOGENOUS RETROVIRUS AND HUMAN BRAIN DISEASES NOVEMBER 6, 2003 HELD AT THE MARRIOTT HOTEL IN BETHESDA, MD INTRODUCTION TO THE PROGRAMS AND RESOURCES OF THE STANLEY MEDICAL INSTITUTE Robert Yolken, Johns Hopkins University School of Medicine and Michael Knable, Maree Webster, Stanley Medical Research Institute WHY LOOK FOR INFECTIOUS AGENTS IN SCHIZOPHRENIA AND BIPOLAR DISORDER? E. Fuller Torrey, Stanley Medical Research Institute, Bethesda, MD HUMAN ENDOGENOUS RETROVIRUS W IN SCHIZOPHRENIA Håkan Karlsson, Karolinska Institute, Sweden THE HUMAN ENDOGENOUS RETROVIRUS W GAG PROTEIN Sarven Sabunciyan, Stanley Division of Developmental Neurovirology, Johns Hopkins University, Baltimore, MD IMMUNOHISTOCHEMICAL STUDIES OF HERV-W AND NEUTRAL AMINO ACID TRANSPORTERS (ASCT 1 AND 2) IN THE BRAINS OF PATIENTS WITH SCHIZOPHRENIA, BIPOLAR DISORDER AND DEPRESSION Serge Weis, Stanley Medical Research Institute, Bethesda, MD IMMUNOPATHOGENICITY OF MSRV ENVELOP TARGETING BRAIN MACROPHASES/MICROGLIOCYTES: A COMMON PATHOGENIC PATHWAY FOR MULTIPLE SCLEROSIS AND SCHIZOPHRENIA, WITH COMMON IMMUNOTHERAPEUTIC OUTCOMES? Hervé Perron, BioMerieux, France RETROVIRAL SEQUENCES OF THE HUMAN GENOME. CHARACTERISATION AND RNA EXPRESSION Jonas Blomberg, Uppsala University, Sweden HERV-K POLYMORPHISMS IN HUMAN POPULATIONS John Coffin, Tufts University School of Medicine, Boston, MA ENDOGENOUS RETROVIRUSES AND RESISTANCE TO EXOGENOUS RETROVIRUS INFECTIONS Jonathan Stoye, National Institute for Medical Research, United Kingdom CONTRASTING EVOLUTIONARY HISTORIES OF DIFFERENT HERV FAMILIES Javier Costas, Complexo Hospitalario Universitario de Santiago, Spain RECENT EVOLUTION OF HERV-K Jack Lenz Albert Einstein College of Medicine, Bronx, NY IMPACT OF RETROELEMENTS ON HUMAN GENE REGULATIONS Patrik Medstrand, Lund University, Sweden CONTRIBUTIONS OFENDOGENOUS LTRs TO TRANSCRIPTIONAL REGULATION OF HUMAN GENES Dixie Mager, Terry Fox Laboratory, Canada HERVd: A COMPREHENSIVE DATABASE OF HUMAN ENDOGENOUS RETROVIRUSES Vaclav Paces, Institute of Molecular Genetics, Prague, Czech Republic NP9 PROTEIN OF THE HUMAN ENDOGENOUS RETROVIRUS K INTERACTS WITH LNX (LIGAND OF NUMB PROTEIN X) N. Mueller-Lantzsch, Institut für Mikrobiologie und Hygiene, Germany HERV-K (HML-2) INSERTIONS DISTINGUISHING HUMAN GENOME FROM NON-HUMAN PRIMATES Yuri Lebedev, Shemyakin-Ovchinnikov Institute, Russia POSTERS QUALITATIVE ASSESSMENT OF RETROVIRAL ACTIVITY IN HUMAN BRAIN AND TISSUES Oliver Frank, Med. Klinik III, Universitätsklinikum Mannheim, Germany VIRAL MICROARRAY STUDIES; RETROVIRUSES Concha Goldberg, Stanley Medical Research Institute, Bethesda, MD STUDIES OF THE NOVEL ENDOGENOUS MURINE LEUKEMIA PROVIRUS HEMV Christopher Tipper, Tufts University School of Medicine, Boston MA THE EXPRESSION OF THE HERV-K ENVELOPE PROTEINS ALTERS GENE EXPRESSION IN RAJI CELLS Sarven Sabunciyan, Lorraine Brando, Stanley Division of Developmental Neurovirology, Johns Hopkins University, Baltimore, MD ENDOGENOUS RETROVIRUS IN HERV-W PROTEINS IN HUMAN BRAINS: EVIDENCE FOR PATHOPHYSIOLOGICAL MODULATION OF GAG AND ENV EXPRESSION IN DEMYELINATING DISEASE Hervé Perron, BioMerieux, France MSRV (MULTIPLE SCLEROSIS ASSOCIATED RETROVIRUS) DISPLAYS PRO-INFLAMMATORY PROPERTIES ON ANTIGEN PRESENTING CELLS Patrice Marche, Laboratoire d’Immunochimie, CEA-G/DRCDC/ICH, INSRUM U548, France MEASURING mRNA QUALITY IN POSTMORTEM HUMAN BRAIN TISSUE Suad Diglisic, Christine Miller, Stanley Medical Research Institute, Bethesda, MD and Stanley Division of Developmental Neurovirology, Johns Hopkins University, Baltimore, MD A METHOD TO DETECT CONSERVED TRANSPOSABLE ELEMENT INSERTIONS IN ORTHOLOGOUS REGIONS BETWEEN SPECIES Patrik Medstrand, Lund University, Sweden