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CURRICULUM VITAE
Name: HUGHES, Ian Edward
Date of Birth: 9th August 1941
Marital Status: Widowed, 2 children (b 1968 and 1971)
Religion: Church of England
Nationality British
Qualifications:
BSc Pharmacy 2(i) Leeds, UK 1962
BSc Pharmacology 2(i) Leeds, UK 1963
PhD Pharmacology, Leeds, UK 1965
I am a National Teaching Fellowship Holder and a member of the Higher Education Academy.
Appointments: (Bold = current)
2004– Privy Council lay appointee to General Medial Council (2004-2009)
2004– Member Wellcome Trust/Medical Research Council Biobank Ethics and Governance
Council
2003- Privy Council lay appointee to the General Osteopathic Council (2003-2008)
2001- UK National Teaching Fellowship holder
2000- Co-director, Higher Education Academy Centre for Bioscience (20% WTE)
1999- Professor of Pharmacology Education, School of Biomedical Sciences, University of Leeds
1998– Chairman of Leeds Mental Health NHS Teaching Trust (to 11/2005)
1998- Chairman International Union of Pharmacology Section on Teaching
1998–2002: Director, HEFC's Teaching and Learning Technology Programme project 83: Implementing
Technology-Based Teaching in Pharmacology (20%WTE)
1998–2002: Director, European Pharmacology Thematic Network (EU Socrates)
1996–2004: Academic sub-Dean of Medicine Phase I (30% WTE)
1996-1998: Chairman of Calderdale Healthcare NHS Trust
1994-1996: Director, Pharmacology Higher Education Network (DfEE funded, 10%WTE)
1993-2000: Director, HEFC's TLTP2 project 76, (pharma-CAL-ogy); 10%WTE
1986-1996: Non-executive director/member Calderdale Healthcare NHS Trust
1984-1990: Acting Head of Department, Dept of Pharmacology, University of Leeds, UK
1979-1999: Senior Lecturer in Pharmacology, Dept of Pharmacology, University of Leeds, UK
1979-1968: Lecturer in Pharmacology, Dept of Pharmacology, University of Leeds, UK
1966-1968: Senior Tutor in Pharmacology, Department of Pharmacology, University of
Western Australia, Perth, WA 6009
1966-1966: Assistant Lecturer in Pharmacology, Department of Pharmacy and
Pharmacology, University of Leeds, UK
Seconded to:
University of Western Australia (1974 - 1975). Provision of research & teaching assistance
University of Guyana, Georgetown, Guyana, South America (Jan 1978 - April 1978). British Council
appointment as adviser on pharmacy teaching in Guyana.
University of Kuwait (August 1985). Adviser on new Pharmacy school development in Kuwait.
I was the British Pharmacological Society Australasian Visitor for Pharmacology (1998/9)
In 2002 I was honoured to be made the Academic Correspondent for the Reial Academia de Farmacia
de Catalunya.
R E S E A R C H into both the scientific and the educational aspects of pharmacology
Grants and contracts (c)
Medical Research Council (equipment, 1969, £16,000)
University of Leeds Research Fund (1975, £300)
Medical Research Council (1975, £11,000)
Organon International Ltd (1976, £15,000)
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The Garfield Weston Foundation (1980, £2,000)
The Yapp Education & Research Trust (1981, £750).
Science & Engineering Research Council (CASE with Organon International Ltd) (1981, £18,000)
Medical Research Council (1982, £14,000)
University of Leeds Research Fund (1983, £350)
The Nuffield Foundation (1983, £500)
Stirling-Winthrop Ltd (1985(c), £2,000)
Wellcome Foundation (1987, £700)
British Pharmacological Society Travel Grants (1987, 1988, 1990).
Viratek Ltd (1988(c), £1050)
Duphar Pharmaceuticals Ltd (joint with University of Amsterdam) (1988; £25,000).
Wyeth Pharmaceuticals Ltd (1989, £7,000)
The Royal Society (1990, £2,000; research in Australia)
EEC COMETT grant joint with University of Amsterdam (1990; ECU170,000 over 3 years). To
develop " MicroLabs in Pharmacology ".
HEFC Teaching and Learning Technology Programme grant (£651,000 over 3 years from 1993).
Hazelton Ltd (1994(c), £8,000)
HEFC continuation funding for TLTP pharma-CAL-ogy project (£97,000 over 3 years from 1996)
EU Leonardo grant to participate in the phytophar project (1998, 12,000ECU)
EU Erasmus/Socrates grant to the European Pharmacology Network (250,000ECU over 4 years from
1998) to discover and develop European Teaching aids.
HEFC Teaching and Learning Technology Programme phase 3 (£283,000 over 3 years from 1998)
EU Leonardo grant; develop learning methods for phytophar project (1999, 20,000ECU over 2 years)
National Teaching Fellowship grant (2001, £50,000)
Jointly, HEFCE funding for Higher Education Academy Centre for Bioscience (£300,000/year from
2000)
Jointly, HEFCE funding for IDEAS CETL (£0.5m/y for 5 years)
Interests - Research into both the scientific and the educational aspects of pharmacology. I have
published over 70 refereed full papers in major journals in the areas of:
- my first love, effects of drugs on muscle, on receptors and on transmitter function at various peripheral
and central sites. My work in animals with the antidepressant mianserin at a very early stage in its
development led directly to the investigation of its cardiotoxicity in man and its establishment as an
antidepressant with little cardiotoxcity in overdose. I was one of the first to apply classical quantitative
pharmacological methods to identification of receptors involved in the control of transmitter release in
brain slices.
- discovery and development of computer simulations of pharmacological preparations and their
establishment as effective teaching aids. I have been involved in this work since 1983 and the programs
I have devised resulted from the extensive testing of the real performance of animal preparations in
comparison with a variety of possible simulation models to obtain robust and flexible simulations. These
are in use in Universities in more than 30 countries over 6 continents and in the pharmaceutical
industry. One of these programs was the Prize winner of the International Multimedia Festival held in
conjunction with the 2nd World Congress of Alternatives to Animals in Utrecht, 1996
- development and testing of the educational effectiveness of both technology based and nontechnology based innovative teaching methods in pharmacology. In the late 70s I devised and
evaluated several MCQ-based self teaching and self-assessment systems and chose to implement a
computer-based system. The outstanding success of this system led, in the early 80s, to collaboration
with the Computer-Based Learning Unit to develop a distributed MCQ-based self teaching system which
became fully operation on the campus wide network in 1983/4. In 1985-7 I developed a computer based
tutor system and became involved more broadly in innovative teaching through my work with the
Enterprise in Higher Education Programme. With EHE funding I developed self- and peer- marking
schemes for practical work and assessment of communication and presentation skills. In 1993, my
involvement and experience in this area contributed to my successful application for a Teaching and
Learning Technology Programme (TLTP2) project, pharma-CAL-ogy, which I directed. The aims of this
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project were to develop, evaluate and deliver technology based teaching to undergraduates, to improve
teaching quality, to improve teaching efficiency and to save staff time. This involved leading a
consortium of 25 UK universities with a budget of £651,000. The project over-fulfilled its aims, was
described as "outstandingly successful" by the independent assessors and was used as a case study in
the HEFCE report (June 99/39). In 1996 I obtained, from TLTP, continuation funding for this project
(£97,000) and in 1999 I took the project into control by the British Pharmacological Society. Building on
these successes I became a member and section leader of Phytophar - a group supported under an EU
Leonardo programme grant (1997) to develop European co-operation in phytopharmaceuticals and
technology-based teaching about phytopharmaceuticals. Further funding under this project was
received in 1999.
In 1998 I made the only successful application from the University of Leeds for a TLTP (phase 3) project
(£283,000) to implement technology based teaching in pharmacology courses. This was the only project
funded in the biological science area. I led this TLTP3 consortium of 26 UK universities which met all its
objectives and delivered a very successful set of project outcomes.
I have also been active in developing non-technology based teaching methods. Part of this work has
involved me developing, in conjunction with AstraZeneca staff, the Zeneca Teaching Day. This teaching
pack provides a resource to enable pharmacology teachers to provide 1-2 days teaching on Drug
Discovery and Development. The methods use are partly technology-based and involve group working,
problem solving and communication skills. This pack is in use in more than 50 universities and in
training in several pharmaceutical companies.
I currently pursue this area of work on a broad discipline base and at national level as Co-director of the
Higher Education Academy Centre for Bioscience (established at Leeds in April 2000) and which has
secure funding (at least £300,000/y to 2009) from the UK Funding Bodies.
Other areas of work in which I have been involved and have published include: investigation of and
research into aspects of the curriculum and attitudes to teaching across the UK; synthetic and analytical
chemistry; pharmacokinetics (man & animals); acute toxicity testing of antidepressants; psychological
assessment of individuals abusing drugs and biochemical pharmacology
I have done contract/consultancy work for Organon, Stirling-Winthrop, Viratek, Wyeth and Hazleton. I
have successfully supervised PhD/MPhil students and given >70 presentations to learned societies.
International visitors
With regard to my work on the use of technology in pharmacology teaching and the
development of innovative teaching methods I have had, during the last 10 years, international visitors
working with me on more than 15 occasions.
Invited lectures and workshops
I have given invited lectures at Zeneca, Wyeth, Pfizer, Duphar, the DTI and DfEE, at
symposia organised by the Universities Federation for Animal Welfare, by the Association for Science
Education, at each of the 9th to the 13th International World Congresses of Pharmacology and at
various medical schools in the UK and overseas. In 1988 I held a Royal Society Travel Grant which
enabled me to travel to Universities throughout Egypt lecturing on my experiences with computers in
education. In 1998-9 I spend 6 weeks touring Australasia as the joint British Pharmacological
Society/Australian Society for Clinical and Experimental Pharmacology and Therapeutics (ASCEPT)
Australasian Visitor for Pharmacology.
I have organised/co-organised/chaired several International Workshops or Symposia in the
UK and overseas [e.g. Ethical Pharmacology (Latvia 2000), Platforms for Alternatives to Animal
Experiments (Brussels 2000), Animal experimentation in pharmacology teaching (Melbourne 2000),
pharNet - developing international co-operation in pharmacology teaching (Bellagio, Italy 1998);
Alternatives to Animals in Teaching in Higher Education, (Crete 1998)].
In 2000 I accepted invitation to speak in Latvia, Belgium, Australia, New Zealand, Figi and
Italy and in 2001 in India, Canada, France, the Czech Republic and Turkey. These speaking
engagements were becoming excessive and I now accept a maximum of 3 per year.
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Refereeing
I have acted as a referee for papers in the British Journal of Pharmacology, Journal of
Pharmacy & Pharmacology, European Journal of Pharmacology, Biochemical Pharmacology,
Neuropharmacology and Journal of Autonomic Pharmacology. I have acted as referee for MRC project
grants, applications to the Nuffield Foundation, the Wellcome Trust, the Radwan Trust for Animal
Welfare, the CIBA-GEIGY Fellowship Trust and the University of Sheffield Grants Committee.
Consultancy
I have acted as a consultant to Guyana Pharmaceuticals Ltd on development of drug production in
Guyana, to the University of Sheffield on Quality Assurance matters and as an expert witness for the
police or for defending councils in cases involving drugs.
Publications
A list of publications is available elsewhere.
TEACHING
Grants
The Nuffield Foundation (1983, £500; 1985, £1,000)
Royal Society Travel Grant to visit Egypt lecturing on pharmacology education (1988).
Pfizer Ltd; to support undergraduate teaching at Leeds (1988; £20,000 over 5 years).
British Council Travel Grant to develop links with the University of Nancy (1989, £250).
Department of Employment Higher Education Pharmacology Network grant (£15,000;
1994-5)(renewed 1995-96; £15,000).
Leeds University ADF grant (£22,500) to develop the pharmacology integrated lecture support
system (PILS) and to implement it at Leeds (1996)
Department for Trade and Industry (DTI) grant (£56,000) to develop a webpage for the
British Pharmacological Society (1997) and its educational activities.
See also above for grants for IDEAS CETL and Higher Education Academy Centre for Bioscience
Innovative Teaching in Pharmacology
My long-term interest in innovative methods of pharmacology teaching has had a significant impact both
on my own teaching and that in the (then) department of Pharmacology at Leeds. I have developed and
introduced self- and peer- marking schemes for practical work; communication and presentation skills
taught explicitly in the course; expanded industrial placements; group work taught explicitly and utilised
in mainstream teaching. These developments have not been confined to Leeds and dissemination of the
innovation and good practice was supported in September 1994 when I was awarded a grant of £15,000
from the DfEE to establish and lead a national Higher Education Discipline Network (pharmacology) to
introduce and share innovative teaching methods nationally, to promote contacts between
pharmacology teachers and to liaise with employers with the aim of enhancing the quality and relevance
of pharmacology courses. The Pharmacology Network was one of the few to deliver its contracted
objectives and to be awarded second year funding (£15,000). Its work has now been subsumed into the
activities of the Education Committee of the British Pharmacological Society.
The activity of the Network has made a significant impact on the teaching methods used in
pharmacology across the UK. Part of this work involves the introduction of a national core curriculum in
pharmacology which I have written, consulted about nationally and which is now adopted by the national
Committee of Heads of Pharmacology units. This work has come together with work with the Quality
Assurance agency on benchmarking and frameworks in which I represent the discipline of
pharmacology.
In 1998 I won funding over 4 years (250,000ECU) from the EU Erasmus/Socrates Thematic Networks
program to form a European Pharmacology Network (EpharNet) which I directed and which placed
Leeds firmly at the centre of a pharmacology network involving 27 countries and over 150 institutions
spread across Europe. The work of this network has now become closely aligned with that of the Higher
Education Academy Centre for Bioscience which I co-direct. I recognition of my work in pharmacology
education in the UK and in Europe I was honoured to be made the Academic Correspondent for the
Reial Academia de Farmacia de Catalunya in 2002.
I am a National Teaching Fellow (appointed 2001) and a member of the IDEAS CETL management
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team (funded 2005).
Under-graduate Teaching
I have taught extensively in Science (Pharmacy, Pharmacology and Combined Honours),
Medical & Dental courses in Australia and the UK and have some experience in teaching in Guyana. I
have a particular interest in course development and have contributed to the re-design of the BSc
courses at Leeds to ensure a broadly based syllabus and to emphasise development of communication
skills, working in teams and development of the ability in students to think on their feet at the laboratory
bench
Quality of teaching
The quality of my teaching as assessed by student feedback is equal to the best delivered
within the Department and is regularly assessed at >4 (out of 5) which is a very high score compared
with other staff teaching on the same module. One of my innovations, the PILS system (Pharmacology
Integrated Learning Support system) is consistently rated as the best feature of the several modules in
which it is used and has now rolled into the development of the ubiquitous virtual learning environments.
Responsibility for new and existing courses
I have co-developed a distance and work-based learning course in partnership with
Covance Ltd to provide training in clinical research and am co-ordinator for all 4 modules of this course.
I have developed and expanded the sandwich placement scheme and introduced a formal
4-years sandwich BSc Honours Pharmacology course. I have arranged a City and Guilds Licentiateship
to be available for award to students who successfully complete the industrial placement year (first 5
awards made in 1998). I hold the role of Industrial Placement Tutor for the whole of the School of
Biomedical Sciences. I have Chaired the Intercalated BSc Course Committee during which time the
numbers of medical students intercalating have expended from 25-120 per year.
External and Internal examining
I am an examiner in all Leeds Medical, Dental & Science courses of which pharmacology
is a component. I have held appointments as external examiner for more than 12 medical, dental or
science courses at various Universities in the UK (currently Birmingham and Imperial College).
Quality Assurance Agency work
I was a HEFCE specialist subject reviewer for Pharmacology and Pharmacy 1998-2000
(Quality Assurance Agency; QAA), co-author of the final report and have represented the British
Pharmacological Society and the Pharmacology Higher Education Network at QAA consultative
meetings.
Post-graduate Teaching
I have supervised MPhil and PhD students and have contributed to courses for postgraduate anaesthetists and psychiatrists. I have examined at DSc, MPhil and PhD levels.
Consultancy
Consultant and sector co-ordinator to the British Council on the joint British Council/DTI
access project to improve contacts between overseas postgraduates and UK industry (85-90).
Work with Professional Society (British Pharmacological Society)
As a winner of the 1998 Professional Body Challenge Award I have obtained a grant
(£56,000) from the Department of Trade and Industry to develop a web page for my professional
association. It is through this web-page that much of the educational material I have been involved in
developing is publicised.
Academic Sub-Dean for Medicine Phase I (years 1 - 3)(1996-2004)
In this role I was responsible for the pastoral care and for monitoring the academic
progress of all students in the 1st, 2nd and 3rd Medical years.
A D M I N I S T R A T I O N (main committees only)
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At International Level
Chairman of the International Union of Pharmacology (IUPHAR) Teaching Section (2002- present)
UK representative at IUPHAR pharNet establishing conference (1998)
Member of the IUPHAR teaching Committee (1994-1998); secretary (98-2002)
UK representative at ECVAM (European Centre for Validation of Alternative Methods) conference on
Alternative in Higher Education. (1998). Co-author of final report.
Member, Advisory Committee for the 3rd World Congress on Animal Alternatives (Bologna 1999).
At National Level
Quality Assurance Agency (QAA) subject specialist reviewer (1998-2000)
British Pharmacological Society, Vice-President (Academic Development)(2001-2004)
Chairman BPS Website committee
Member, BPS Membership Committee and Public Affairs Committee
I represent Leeds Pharmacology on the national Committee of Heads of Pharmacology units
At University Level
Member, University Ethical Committee (99- )
Chairman, University City and Guilds Management Committee (2002- )
Member, Animal facilities co-ordinating committee (90-2001)
Adviser to Students in Lupton and Off-Precinct Flats (1976- )
Member Drugs policy advisory group (98- )
At Faculty Level
Chairman, Faculty HR committee (2003- )
Industrial year co-ordinator for the School of Biomedical Sciences (1998- )
In the National Health Service
I have served as a non-executive on NHS Boards for more than 15 years and I am
currently Chairman of Leeds Mental Health NHS Teaching Trust (approx £90m/year turnover) and
responsible to the Secretary of State for Health for the delivery of Mental Health care to a population of
724,000. I Chair a variety of NHS committees. I am a manager (within the terms of the Mental Health
Act) of the mental illness hospitals in Leeds. I have been appointed by Her Majesty's Privy Council to sit
on the General Osteopathic Council and on the General Medical Council.
GENERAL INFORMATION
Personal and Career Development Courses Attended
*Performance Indicators in Hospitals; Interviewing and Staff Selection Skills; *Mental Health Act
Training Course; *Hearing Staff Appeals against Dismissal; *Normalisation Workshop; Certificated
First-Aider; *Hearing Nursing Staff Appeals against Grading; Counselling Workshop; Staff Selection
and Appointment Workshop; Staff Review and Appraisal Training Course; Financial Management and
Budget Control Workshop; Research Grant Applications Workshop; Student Centred Learning
Workshop; CRAC into Insight Technical Management; Active Learning Workshops (2); Higher
Education for Capability Workshop; Using Learning Contracts Workshop; Project Management (2);
Evaluation workshop; Using the Web; *Planning for change in the NHS; QAA subject specialist
reviewer training; *Human Rights Act; *Measuring Quality in the NHS; The New QAA process;
Arranging work placements; The problem of plagiarism; *Equal opportunities workshop; *Mentoring;
*Appraisal in the NHS
*-related to NHS activities.
Membership of Societies
Fellow of the British Pharmacological Society
Chairman of the IUHAR (International Union of Pharmacology) Teaching Section
Sometime member of the Pharmaceutical Society of Great Britain
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Member of the Research Defence Society
Member, Leeds YMCA
Pastoral responsibilities
As Adviser to Students in Lupton Flats (since 1976) I have responsibility for allocation of
the flats and for the pastoral care and discipline of 350 students living in mixed accommodation
controlled by the University.
Personal information
I am an enthusiastic 'do-it-yourself' man on car and home and a sometime gardener and
reader. As father of two male children I am an expert on mending things and have graduated from
rattles, through trains to hearts and have recently started at rattles again..
Addresses
School of Biomedical Sciences
University of Leeds,
LEEDS LS2 9JT, UK
Tel: +44-(0)113-343-4313 (direct line)
fax +44-(0)113-343-4704; email i.e.hughes@leeds.ac.uk
The Old Vicarage
Church Lane
Horsforth
LEEDS LS18 5LA, UK
Tel/fax +44-(0)113-258-4576