IAEA Regional Training Course on ASSESSMENT OF OCCUPATIONAL EXPOSURE DUE TO INTAKES OF RADIONUCLIDES Measurement of whole body activity in scanning bed geometry Introduction Direct measurement of internal contamination should provide identification of the radionuclide(s) present in the worker and determine the quantity (activity) of those radionuclides. However, direct measurements are only useful if the emission from the radionuclide deposited in the body can be detected with external detectors. This depends on the abundance and energy of the photons emitted and on the pattern of deposition in the body. In many cases, the radionuclide is localized to one organ or body tissue, so that the direct measurement should focus on determination of the activity level in that organ rather than the whole body. Metabolic models and assumptions about the time of intake are used to determine the magnitude of the intake. The internal dose assessment will then be based on this quantity. Objective The objective of this exercise is to demonstrate the steps involved in 1) calibration and 2) use of a counting system for identification and measurement of uptake of a radionuclide in the whole body, and 3) use of the uptake information to determine the intake quantity and the committed effective dose that results from that intake. This information will be useful to those concerned with the planning, management and operation of occupational monitoring programmes including to those responsible for carrying out individual dosimetry due to intakes of radionuclides based on indirect measurements of internal contamination. Scope The exercise is intended to familiarize the students with the procedures used for whole body radioactivity measurements, including energy calibration, efficiency calibration, background measurements, preparation of subjects to be monitored, execution of human measurements, gamma spectrometric evaluation of measurements and recording the results. The exercise will focus on the conduct of phantom measurements and data evaluation by identification of radionuclides incorporated in the phantom and determination of their activities. Following identification of the radionuclide and determination of the quantity in the whole body, data on simulated intake will be provided to enable the students to determine the intake and associated committed effective dose. Measuring Equipment Commercial counting systems such as those from Canberra may be used for this exercise, however the primary components are as follows: Counting Geometry: Scanning bed or fixed bed with scanning detectors. A fixed bed with a fixed detector or detector array could also be used. The bed should be located in a shielded room, or least be part of a well shielded shadow shield counter. Detectors: Sodium iodide or germanium detectors of a suitable size for whole body measurements. If a single sodium iodide detector is used, it should be of a size to offer adequate sensitivity – 203 mm diameter 101 mm is recommended. The sodium iodide should be 76.2 mm x 76.2 mm or less to allow placement near the thyroid. A germanium detector should have a similar size limitation. Germanium detectors should also be of a sufficient size to assure adequate sensitivity – 25% relative efficiency or greater. If a commercial counting system such as that made by Canberra is used, the germanium detectors supplied with the system should be adequate. Electronics: Multichannel pulse height analyzer (MCA) with sufficient number of channels to accommodate high resolution spectra from a germanium detector if used. The use of computer based MCAs facilitates both basic manipulations of spectra and sophisticated operations such as peak search, evaluation, identification and calculation procedures. Ancillary equipment required to extract, amplify and sort electrical signals from the detector, producing a pulse-height distribution (spectrum), including: pre and main amplifiers, analogue-digital converter (ADC) and modules providing DC power supplies (low and high voltage as well). Phantom The phantom should be suitable for simulation of distribution of radioactivity in the whole body, including head, neck and lower limbs. Although BOMAB phantoms probably are the most commonly used, there are other phantoms that would be suitable. The phantom may be as simple as a set of 1 L plastic bottles filled with gels containing the radionuclide(s), with overall dimensions of an adult individual. A few such phantoms are illustrated below. Outline of the Practical 1. Facility familiarization – The facility staff will provide a brief over view of the facility to be used for this exercise, including description of the counting equipment, counting geometry and phantom to be used. If a commercial counting system with data processing software is used, the familiarization should include a description of that software that is sufficient to allow the student to understand its use during the exercise. 2. Energy calibration - The facility staff will demonstrate the energy calibration of the system to be used for the practical, with student participation if appropriate. The demonstration should include description of the source(s) used and the major photons emitted discussion of source positioning, source measurement, and description of the software used, if relevant. 3. Efficiency calibration – The facility staff will explain how the efficiency calibration of the counting system has been performed with the phantom to be used in the practical. If possible, a demonstration should be conducted using a filled phantom. The explanation and/or demonstration should include description of the radionuclides used for calibration, the basis for certification of the source activity (i.e. traceability), and measurement of the source. The demonstration should include description of how the photopeaks are evaluated, with particular emphasis on software processing if a commercial system is used. The facility staff should provide the students with energy dependent efficiency curves for the phantom used in the practical. These curves should cover the energy of the radionuclide to be evaluated. 4. Measurement of the “unknown” – The facility staff will demonstrate loading of the phantom with the unknown radionuclides(s) to be used for the practical. They will demonstrate positioning of the phantom with emphasis on methods used to achieve reproducible positioning. Each student will perform a measurement of the phantom. All measurements should be made with supervision of the facility staff, but the students should do as much of the “hands-on” work as possible, consistent with facility rules and safety. 5. Radionuclide identification – Following the measurement, the students will first evaluate the counting results to determine the energy of the photopeaks and identify the “unknown” radionuclide(s). This will require determining the energy of the photopeaks from the spectra and the energy calibration conducted earlier. From this information and radionuclide decay data to be provided by the facility staff, the students should identify the radionuclide. If a commercial counting system is used, the identification should also be done (with guidance from facility staff) through peak search and built-in radionuclide libraries. 6. Radionuclide quantification – After identification of the radionuclide, the students will determine the net count rate in the primary photopeak(s) using the same techniques that were illustrated during the efficiency calibration. Then, using the efficiency calibration data and the measured phantom-detector separation, the students will determine the emission rate of photons in the primary photopeak(s). Finally, the students will determine the activity of the radionuclide using decay data proved by the facility staff. If a commercial counting system is used, quantification of the radionuclides should also be done using the system software. 7. Determination of intake – Following identification and quantification of the radionuclide(s), the facility staff will provide the students with simulated data on intake, i.e. mode of intake, pattern of intake (acute or chronic) and date. Additional relevant information that may be needed. Using retention data from ICRP 78 or a similar reference, the students will determine the estimated intake value (Bq). 8. Determination of Committed Effective Dose (C.E.D.) – The students will use the intake value determined in step 7, together with dose coefficients from ICRP 78 or similar reference to determine the committed effective dose value that would be assigned to the measurement results. 9. Discussion – Following completion of the practical steps 1-8, the facility staff and lecturers will conduct a discussion to review the experience of the practical, including problems encountered, questions that the students may have and key points that the practical has illustrated. Notes to the Facility Staff and Lecturers This practical is intended to provide an illustration of the steps involved in system calibration, subject measurement and data evaluation for a whole body measurement. It is recommended that more than one unknown radionuclide be used, but no more than three. The most likely unknown radionuclides for this purpose are fission or activation products. One should have a gamma ray between 100 and 200 keV. Emphasis should be given in this practical on the principles involved in routine whole body counting for occupational protection. Manual evaluation procedures (peak identification and quantification) have the value that they illustrate the principles behind the measurement process and help the student better appreciate the advantages (and pitfalls) of more automatic, software based methods. These points should be stressed. Other issues related to operation of a direct measurement facility should also be highlighted during the demonstration, including housekeeping, quality control, etc. The scenario developed as a basis for intake and committed effective dose determination from the counting results should be realistic, but not excessively complicated. It should illustrate the principles involved in making this determination. A scenario based on a case history would be useful. References INTERNATIONAL ATOMIC ENERGY AGENCY, Directory of Whole-Body Radioactivity Monitors, IAEA, Vienna (1970) INTERNATIONAL ATOMIC ENERGY AGENCY, Contamination in Man, IAEA-SM-276, Vienna (1985) Assessment of Radioactive INTERNATIONAL ATOMIC ENERGY AGENCY, Rapid monitoring of large groups of internally contaminated people following a radiation accident, IAEA-TECDOC-746, Vienna (1994) INTERNATIONAL ATOMIC ENERGY AGENCY, Direct Methods for Measuring Radionuclides in the Human Body, Safety Series No. 114, IAEA, Vienna (1996) INTERNATIONAL ATOMIC ENERGY AGENCY, Calibration of Radiation Protection Monitoring Instruments, Safety Report Series No. 16, IAEA, Vienna (2000). INTERNATIONAL COMMISSION ON RADIOLOGICAL PROTECTION, Individual Monitoring for Internal Exposure of Workers, ICRP Publication 78 (1997). INTERNATIONAL COMMISSION ON RADIATION UNITS AND MEASUREMENTS, Direct Determination of the Body Content of Radionuclides, ICRU Report 69, Journal of the ICRU, 3, No.1 2003 (2003).