BIOLOGY 1 STANDARD 4.0 LESSON 4.5B PRINT OUT THIS LESSON BEFORE CONTINUING IN ORDER TO FOLLOW THE DIRECTIONS AND COMPLETE THE ASSIGNMENT. KEEP THESE PAGES IN YOUR NOTEBOOK Genetics and Biotechnology Unit The student will investigate the concepts of genetics and heredity, different methods of reproduction, patterns of inheritance, and genetic disorders; as well as, explore and evaluate the DNA technologies from both a scientific and ethical perspective. Lesson 2b - Structure and function of DNA and RNA A. Notes DNA structure and DNA replication B. Notes DNA structure/ DNA replication / RNA structure Complete the worksheet while reading though the above note links Name ____________________________ Date completed _____ 1. What does DNA stand for: ____________________________________ 2. _________________ Are the basic building blocks of all nucleic Acids. 3. A nucleotide contains what 3 parts: _____________________, ___________________, __________________ 4. DNA contains the bases: __________________, ___________________, ________________________, and _____________________. 5. _________________________ is the sugar found in all DNA molecules 6. The shape of a DNA molecule is called the __________________________. 7. The base thymine always pairs with ___________________ 8. The base cytosine always pairs with ___________________ 9. _______________________ is the term used to refer to DNA when it makes an exact duplicate of itself. 10. Give the base sequence of the complementary DNA strand. Original strand: T T A C G G T C A C C A ---Complementary strand : Use this link to view a video on DNA before continuing with the lesson (Click on the double helix) Use this link to build a DNA Model Nucleic Acids Continued Nucleic Acids contain __________ and ___________ as their examples. DNA is responsible for the code of every ______________ in an organism body. The monomers of DNA are called _______________. Each of these ________________ contains a sugar, one of 5 different bases and a phosphate. This is an example of a simple nucleotide. S -B | P There are 2 types of sugars: ___________________ and __________________. There are 5 types of bases: DNA contains: Adenine, Guanine, Cytosine, and Thymine. While RNA contains: Adenine, Guanine, Cytosine, and ____________ Draw the 4 different types of nucleotides for DNA in the space below: Use D for the sugar and the underlined letters for the bases. The P is the same in all nucleotides. The nucleotides can only combine in the following order: A - T and C - G. The bases never touch the P. Let us produce a DNA molecule using the following sequence of DNA bases: A C TC A GG T A T T T T T T T T T T T This DNA will twist several times forming the unique corkscrew shape called the __________________. Do this activity before continuing with the lesson C. Activity: A handful of DNA - great visuals! RNA is a bit different in structure, since it has the base Uracil replacing the base _________________. The sugar is different since ____________ replaces the Deoxyribose in the nucleotide. Most of RNA has a linear structure and not that of a ladder. RNA's functions vary from taking the code for a protein to the ribosome (m-RNA) to bringing in the correct amino acids to produce the protein (t-RNA). DNA Replication: This is the process by which DNA produces an exact copy of itself. There are 4 basic steps to this procedure. 1. DNA unwinds. 2. The double helix will unzip. 3. The complementary bases will be added to each side of the old molecule. and 4. The DNA's will rewind or twist. Each of the 2 DNA molecules will contain 1/2 new material and 1/2 of the original molecule. Here is another great site with animation to learn about DNA