Drug Information Sheet ("Kusuri-no-Shiori") For Injectables
Newly-created : 01/2011
Information is based on approvals granted in Japan. In some cases, the approved details may vary in
countries other than Japan.
Brand Name：Pazucross Injection
500mg
DESCRIPTION
Nonproprietary
(Generic) Name：Pazufloxacin mesilate
THIS
INJECTION
WORKS FOR
Classification：
Pazucross is for the treatment of bacterial infections. The pazufloxacin mesilate
contained in Pazucross is one of a group of antibacterial agents called new
quinolones which work by killing bacteria that cause infections.
・Tell your Health Care Provider:
- If you ever had any unusual or allergic reaction to any medicines.
- If you are or your parents or siblings are liable to have allergic reactions, such
as asthma, rash, urticaria.
- Patients with kidney/heart disease, myasthenia gravis.
BEFORE
RECEIVING
INJECTION
- If you have previously had fits or suffer from epilepsy.
・Dosage Schedule:
Your doctor decides the duration of treatment depending upon the severity. It is
within 14days in principle.
・Administration:
Usually, Pazucross is given by intravenous drip infusion over a period of 30‐60
minutes twice a day.
・Others:
If you are already pregnant, may possibly be pregnant, or are breast-feeding, tell
your doctor before taking Pazucross.
SIDE
EFFECT(S)
・An injection may cause some unwanted effects.
◎Check with your doctor immediately if any of the following side effects occur:
<Acute renal failure > Urine volume decreased, swelling, headache, loss of
appetite, thirst.
<Hepatic function disorder, jaundice> Loss of appetite, nausea, yellowing of the
skin on the whites of the eyes, dullness.
<Pseudomembranous colitis > Watery diarrhoea, frequent diarrhoea containing
blood and mucus, fever, abdominal pain, nausea, vomiting, loss of appetite.
<Agranulocytosis, decreased platelet count> Sore throat, fever, stomatitis, blue
spots indelible even at a push on the skin, red spots or bruises on limbs, bleeding
tendency from the gums or nose.
<Rhabdomyolysis> Numbness of the limbs, weakness, sore muscles, stiffness,
dullness, urine like red wine.
Continued on next page
Pazucross Injection 500mg
<Psychological symptoms such as confusion and hallucination>
Disturbed/confused, disoriented, to see or hear something that is not really
there.
<Convulsions>
<Shock, anaphylactoid reaction (dyspnoea, oedema, redness, etc.)> Chills,
nausea, abdominal pain, pale face, cold sweat, dizziness, palpitation, rash,
itching, urticaria, choking feeling in the chest, respiratory distress, swelling,
redness.
<Toxic epidermal necrolysis, oculomucocutaneous syndrome> Fever, red skin,
rash, blisters, soreness in mucous membrane of mouth, nose, conjunctiva,
blisters are easily broken, severe skin reactions such as burn, blurred vision.
<Interstitial pneumonia> Fever, cough, respiratory distress, chest pain,
dullness.
<Hypoglycaemia> Sweating, trembling, dizziness, chills, palpitation, craving for
food, weakness.
<Tendon disorders such as achilless tendonitis and tendon rupture> Pain or
swelling seen in the Achilles tendon area, difficulty of going up and down the
strains, rupture of Achilles tendon.
<Injection site reactions> Pain, rash, swelling, induration of injection site.
◆Check with your doctor early if any of the following side effects occur:
◇Other side effects not listed above:
<Anaemia> Fatigability, whiting of the back of your eyelids or your face.
<Diarrhoea> <Abdominal distension> <Hypoaesthesia> Derangement of
sensory. <Abnormal feeling> Feeling ill, strange feeling, floating feeling.
<Dry mouth> <Glossitis> Rough tongue, tongue stinging.
・If you notice any other unusual symptoms, check with your doctor.
PRECAUTIONS
AFTER
INJECTION
OTHERS
INFORMATION
GIVEN DATE
INFORMATION
PROVIDED BY
For more detailed information about this injection, ask your health care provider.