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CURRICULUM VITAE
EFFROSYNI D MANALI, MD
LECTURER
National & Kapodistrian University of Athens
Medical School of Athens, GREECE
ATHENS 2013
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1. PERSONAL INFORMATION
Name:Effrosyni Manali
Date of birth: October 8th, 1970
Birth Place: Athens
Citizenship: Greek
Home Address: 10 Samou str, Agios Stefanos 145 65 Athens Greece
Home Telephone number: +30 210 8145 883
Work place Address: “Attikon” University Hospital, 1 Rimini Str, 12461 Haidari, Greece
Telephone number at work: +30 210 5832361 , +30 210 5831184
Email address: fmanali@otenet.gr
Fax number: +30 210 5836414
Actual Position: Lecturer, 2nd Department of Pulmonary Medicine, Attikon University Hospital, National
and Kapodistrian University of Athens Greece
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QUALIFICATIONS
1994
2002
2002
2004
Medical Diploma (Very Good),
Aristotelion University of Thessaloniki, Medical School of
Thessaloniki, Greece
Specialty in Pulmonology (cum laude),
Medical School of Athens, Greece
United States Medical Licensing Examination (USMLE) Step I
United States Medical Licensing Examination (USMLE) Step II
Doctoral Thesis (cum laude),
Medical School of Athens, Greece
PROFESSIONAL EXPERIENCE
12/94-12/95
Compulsory G.P Service of the Greek Provinces, in Fthiotida area,
Greece
03/97-04/02
Fellow in Pulmonology, 3rd Department of Pulmonary Diseases,
Sismanoglion General Hospital, Athens, Greece, Head Dr.
V.Polychronopoulos
09/98-02/99
Fellow in Critical Care, Reanimation Médicale, Hôpital
Universitaire “Cochin”, Paris France, Professeur JF Dhainaut
12/00-03/02
Fellow in Internal Medicine, 4th Department of Internal Medicine
Medical School of Athens, Greece, Professor H.Giamarellou
10/02-01/04
Fellow of Pulmonology in the Department of Pulmonary and
Critical Care, The Cleveland Clinic Foundation, Cleveland, OH,
USA. Professor Dr. Atul C. Mehta
Lecturer 407/80 in Pulmonology, 4th Department of Internal Medicine,
“Attikon” University Hospital, Haidari, Athens
National and Kapodistrian University of Athens, Medical School,
of Athens, Greece, Professor H.Giamarellou
08/04-now
Pulmonary Hypertension Clinic, “Attikon” University Hospital,
Haidari, Athens, Greece, Head Associate Professor S.Orfanos
09/06- 03/10
Lecturer 407/80 in Pulmonology 2nd Pulmonary Department, “Attikon”
University Hospital, Haidari, National and Kapodistrian University of Athens, Medical School of Athens,
Greece, Professor SA Papiris
03/10-01/13
Registrar NHS, 1 st Department of Pulmonary Medicine, National and
Kapodistrian University of Athens Greece, “Sotiria” Chest Diseases Hospital, Athens, Greece, Professor
N.Koulouris
01/13- Lecturer, 2nd Department of Pulmonary Medicine, “Attikon” University Hospital, National and
Kapodistrian University of Athens Greece, Professor SA Papiris
LICENCES TO PRACTICE MEDICINE
02/04-08/06
1994:
2002:
Athens-Greece (Medicine)
Athens-Greece (Pulmonology)
Foreign Languages
1. English: Certificate of Proficiency in English, University of Cambridge
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French: Diplôme d’études françaises 2e degré, Sorbonne II
German: Zertificat Deutsch als Fremdsprache, Goethe Institut
Teaching work
 9 Chapters in Books of the University of Athens Greece in Pulmonary Medicine, Critical Care,
Internal Medicine and Oncology
 2004-2013 Graduate and Postgraduate courses in Pulmonary Medicine and Internal Medicine at
students and fellows in pulmonary medicine and internal medicine, National and Kapodistrain
University of Athens Greece
SCIENTIFIC SOCIETIES
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Hellenic Thoracic Society
European Respiratory Society
Hellenic Society of Pulmonary Hypertension
Hellenic Society of rare and orphan diseases
HONORS
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May 2002:
Scholarship of the Hellenic Thoracic Society
August 2002:
Scholarship of the Onassis Foundation, Greece
September 2005: Scholarship of the Amphiaraeion Foundation of
Chemotherapeutic studies
Award for best announcement for “Cardiopulmonary Exercise testing in idiopathic
pulmonary fibrosis”, 20 th Annual Congress of the Hellenic Thoracic Society, Athens
Greece 11/2011
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Wiener Klinische Wochenschrift
Journal of Postgraduate Medicine
Pneumon
Journal of Clinical Anesthesia
Thoracic Cancer
BMJ Open
Lupus
Journal of medical case reports
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ANNOUNCEMENTS IN INTERNATIONAL MEDICAL CONGRESSES
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Karagiannidis N, Manali E, Polychronopoulos V. Changes in the frequency and histological types
of lung cancer in the last decade in patients aged younger than 45 years that underwent FOB. Oral
presentation 10th World Congress for Bronchoesophagology. 1998 Budapest HUNGARY
F.Diamantea, E.Manali, N.Tsakanika, V.Polychronopoulos. The diagnosic value of HRCT, BAL,
TBB in interstitial lung diseases. ERS Annual Congress 1999, Madrid, SP
K.Tsakanika, E.Manali, V.Polychronopoulos. Correlation of the number of asbestos bodies in
BAL, the clinicopathological findings and the final diagnosis in 30 patients with exposure to
asbestos. World Congress on Lung Health and the 10 th ERS Annual Congress, September 2000,
Florence I
N.Karagiannidis, Ch.Mermingis, E.Manali, V.Polychronopoulos. The contribution of fiberoptic
bronchoscopy and associated techniques in the diagnosis of pulmonary diseases. ACCP 1999,
Chicago IL
A.Blana, E.Elina, E.Manali, V.Polychronopoulos. Immunocytochemical expression of P-gp and
GST pi in lung cancer. Oral presentation 14th International Congress of Cytology, May 2001
Amsterdam NL
G.Vlachogeorgos, E.Manali, V.Polychronopoulos. The role of the expression of GST-pi and P-gp
in cytologic specimen in the outcome of patients with lung cancer. ACCP 2001, Philadelphia PN
G.Vlachogeorgos,
E.Manali,
Ch.Mermingis,
A.Blana,
S.Legaki,
N.Karagiannidis,
V.Polychronopoulos. Changes in the expression of GST-pi and P-gp in bronchoscopic specimen
of patients with lung cancer after chemotherapy. Annual Congress of European Respiratory
Society. September 2001 Berlin Germany
E.Manali, V.Polychronopoulos, H.Giamarellou. The role of fiberoptic bronchoscopy and PSB in
the diagnosis of community acquired pneumonia. ACCP 2003, San Diego CA
Vlachogeorgos G, Manali E, Polychronopoulos V. Expression of Glutathione-s-transferase pi as
prognostic factor for the response to chemotherapy and survival for patients with inoperable non
small cell lung cancer. ACCP 2003, Orlando FL
Manali ED, Mazzone P, Bhattacharyya N, Combair S, Janocha A, Slattery S, Erzurum S,
Banerjee S. Variant forms of DNA polymerase in human lung cancer. ACCP 2003 Orlando FL
E.Manali, A.Papadopoulos, K.Kanellakopoulou, M.Tsivra, V.Polychronopoulos, H.Giamarellou.
Significance of Bronchoscopy and invasive techniques in the diagnosis of community-acquired
pneumonia. ECCMID May 2004, Prague Czech Republic
Manali ED, Fleming P, Mughal MM, Thornton J, Xu M, Gildea TR, Mehta AC. High Dose Rate
Endobronchial radiation and multimodality treatment for palliative therapy of malignant airway
obstruction. Our experience. 13th World Congress for Bronchology and Bronchoesophagology.
June 2004 Barcelona Spain
Kontopidou F, Papadomichelakis E, Manali ED, Antodianou A, Athanassia S, Koratzanis E,
Mavrou E, Armaganidis A, Giamarellou H.Colonization Surveillance Predicts Microbial Etiology
of Infection in the Critically Ill. Oral presentation in the 71st Annual Scientific Assembly of the
American College of Chest Physicians. October 31 st , Montreal CANADA 2005 [CHEST
2005; 128 (supplement) 143S]
Papiris SA, Kollintza A, Manali ED, Karatza M, Milic-Emili J, Roussos C, Daniil Z. CD8+ T
Lymphocytes and neutrophils in bronchoalveolar lavage from patients with idiopathic pulmonary
fibrosis are associated with clinical and functional parameters. Oral presentation in 71st Annual
Scientific Assembly of the American College of Chest Physicians. November 1 st Montreal
CANADA 2005 [CHEST 2005; 128 (supplement): 169S]
Manali ED, Stathopoulos GT, Kollintza A, Kalomenidis I, Milic-Emili J, Roussos Ch, Daniil Z,
Papiris SA. The Medical Research Council dyspnea scale as a predictor of disease progression in
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idiopathic pulmonary fibrosis. European Respiratory Society Annual Congress Munich,
Germany, 3 September 2006
Tsiodras S, Manali ED, Fytrou E, Papadopoulos A, Poulakou G, Karagiannopoulou S,
Kanellakopoulou K, Giamarellou H. Factors affecting influenza immunization among health care
workers. A tertiary care hospital case control study. IDSA Toronto 2006
Manali ED, Stathopoulos GT, Kollintza A, Kalomenidis I, Milic-Emili J, Roussos Ch, Daniil Z,
Papiris S. The medical research council chronic dyspnea scale as a predictor of disease
progression in idiopathic pulmonary fibrosis. Annual Conference of European Respiratory
Society. Munchen 2006
Tsimogianni A, Papiris S, Kanavaki S, Manali ED, Michalopoulou P, Sotiropoulou C, Roussos
Ch, Kotanidou A. Associations of COPD severity of exacerbation with sputum microbiologic
profile and long-term survival. ERS Berlin 2008
Manali E, Lyberopoulos P, Triantafillidou C, Kolilekas L, Sotiropoulou C, Milic-Emili J,
Roussos C, Papiris S. Medical Research Council dyspnea scale: the relationship with
cardiopulmonary exercise test and 6-minute walk test in idiopathic pulmonary fibrosis. ERS
Vienna 2009
Kolilekas L*, Spyridopoulos T*, Manali ED, Mainta E, Markoulaki D, Kontopoulou C, Argentos
S, Sotiropoulou C, Kelekis N, Papiris SA. Radiologic evaluation of patients suspected of
pulmonary embolism at a pulmonary emergency department of a tertiary hospital: correlations
with clinical and laboratory findings. ESTI Bern 2010 (equally contributed)
Kolilekas L*, Vlami K*, Manali ED, Lyberopoulos P, Triantafillidou C, Markoulaki D,
Gyftopoulos S, Sotiropoulou C, Karakatsani A, Papiris SA. Obstructive sleep apnea in Idiopathic
Pulmonary Fibrosis Patients: correlations of sleep characteristics with parameters of disease
severity and outcome ESRS Lisbon 2010 (equally contributed)
Kolilekas L*, Vlami K*, Manali ED, Triantafillidou C, Markoulaki D, Lyberopoulos P,
Gyftopoulos S, Sotiropoulou C, Karakatsani A, Papiris SA. Sleep disorders and quality of life
questionnaires in idiopathic pulmonary fibrosis patients with obstructive sleep apnea syndrome.
ESRS Lisbon 2010 (equally contributed)
Triantafillidou C, Manali ED, Magkou C, Kolilekas L, Kagouridis K, Sotiropoulos C,
Rontogianni D, Papiris SA. The prognostic significance of fibroblastic foci in idiopathic
pulmonary fibrosis. ERS Barcelona 2010
Kolilekas L*, Vlami K*, Manali E, Lyberopoulos P, Triantafillidou C, Markoulaki D, Kagouridis
K, Gyftopoulos S, Sotiropoulou C, Karakatsani A, Alchanatis M, Papiris S. Obstructive sleep
apnea in Idiopathic Pulmonary Fibrosis. Sleep and Breathing Conference Prague 2011 (equally
contributed)
Kolilekas L*, Vlami K*, Manali E, Triantafillidou C, Lyberopoulos P, Markoulaki D,
Gyftopoulos S, Kagouridis K,Sotiropoulou C, Karakatsani A, Alchanatis M, Papiris S. Obstructive
sleep apnea: quality of life and sleep disorder questionnaires in idiopathic pulmonary fibrosis.
Sleep and Breathing Conference Prague 2011 (equally contributed)
Kolilekas Likurgos*, Manali Effrosyni*, Lyberopoulos Panagiotis, Vlami Katerina,
Triantafillidou Christina, Kagouridis Konstantinos, Gyftopoulos Sotirios, Vougas Konstantinos,
Gaga Mina, Karakatsani Anna, Alchanatis Manos, Papiris Spyros. (equally contributed) “Heart
rate recovery after cardiopulmonary exercise test does not predict survival in patients with IPF and
sleep disordered breathing” Sleep and Breathing Conference Berlin 2013 11-13 April
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ORIGINAL ARTICLES IN INTERNATIONAL MEDICAL JOURNALS (PUBMED)
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Manali ED, Saad CP, Krizmanich G, Mehta AC. Endobronchial findings of Fibrosing
Mediastinitis. Respir Care 2003 Nov; 48(11):1038- 1042 [Pubmed]
Manali ED, Tomford WJ, Liao DW, Farver C, Mehta AC. Mycobacterium Kansasii
endobronchial ulcer in a non-immunocompromised patient. Respiration 2005 May-June; 72(3):
305-8 [Pubmed]
Papiris SA, Kollintza A, Karatza M, Manali ED, Sotiropoulou C, Milic-Emili J, Roussos C,
Daniil Z. CD8+ T lymphocytes in bronchoalveolar lavage in idiopathic pulmonary fibrosis.J
Inflamm (Lond). 2007; 4:14. [PubMed]
Papiris SA, Manali ED, Kalomenidis I, Kapotsis GE, Karakatsani A, Roussos C. Bench-tobedside review: Pulmonary-renal syndromes - an update for the intensivist. Crit Care 2007 May
2;11(3):213 [PubMed]
Papiris SA, Kalomenidis I, Malagari K, Kapotsis GE, Harhalakis N, Manali ED, Rontogianni D,
Roussos C, Moutsopoulos HM. Extranodal marginal zone B-cell lymphoma of the lung in
Sjögren’s syndrome patients: reappraisal of clinical, radiological, and pathology findings. Respir
Med 2007 Jan; 101(1):84-92. Epub 2006 Jun 2. PMID: 16735112 [PubMed]
Manali ED, Papadopoulos A, Tsiodras S, Polychronopoulos V, Giamarellou H, Kanellakopoulou
K. The role of invasive bronchoscopic techniques in the diagnosis of community –acquired
pneumonia in the immunocompetent hospitalized patient: a prospective study. Scandinavian
Journal of Infectious Diseases. Scand J Infect Dis 2007; 4: 1-7 [Pubmed]
ED Manali, G. Stathopoulos, A. Kollintza, J. Kalomenidis, Z. Daniil, J. Milic Emili, Ch. Roussos,
S.A. Papiris. The Medical Research Council CHRONIC dyspnea score predicts survival of
patients with idiopathic pulmonary fibrosis. Respir Med 2008; 102: 586-92 [Pubmed]
Kolilekas L., Kalomenidis I., Manali ED, Liberopoulos P., Papiris S. Reccurent hemoptysis in a
patient with previous tuberculosis. Respiration 2009; 78 (4): 453-454[Pubmed]
L. Kolilekas, ED.Manali, I. Kalomenidis, E. K. Spyrou, SA. Papiris. Unusual case of tracheal
compression in an adult patient. Intern Med 2008; 47: 1069-1070[Pubmed]
L. Kolilekas, I. Kalomenidis, ED. Manali, C.Triantafillidou, E. Brountzos, SA. Papiris.
Cyanoacrylate related pulmonary embolism following percutaneous embolization of varicocele.
(Clinical Communication to the Editor) South Med J 2008; 101: 1073-1074 [Pubmed]
Vlachogeorgos G., Manali ED, Blana E, Legaki S, Polychronopoulos VS, Roussos Ch.
Glutathione-s-transferase pi and P-glycoprotein predict response to treatment and survival in non
small cell lung cancer. Cancer 2008; 114(6):519-526 [Pubmed]
Tsimogianni AM, Papiris SA, Kanavaki S, Stathopoulos GT, Sotiropoulou C, Manali ED,
Michalopoulou P, Roussos Ch, Kotanidou A. Predictors of positive sputum cultures in
exacerbations of chronic obstructive pulmonary disease. Respirology 2009; 14(8): 1114-1120
[Pubmed]
Kolilekas LF, Triantafillidou Ch, Manali ED, Rontogianni D, Chatziioannou NS, Papiris SA. The
many faces of sarcoidosis: asymptomatic muscle mass mimicking giant-cell tumor. Rheumatol Int
2009; 29(11): 1389-1390 [Pubmed]
Tsimogianni AM, Papiris SA, Stathopoulos GT, Manali ED, Roussos C, Kotanidou A .Predictors
of outcome after exacerbation of chronic obstructive pulmonary disease. J Gen Intern Med 2009;
24(9): 1043-1048 [Pubmed]
Papiris SA, Manali ED, Kolilekas LF, Triantafillidou C, Tsagaris I. Acute severe asthma: new
approaches to assessment and treatment. Drugs 2009; 69 (17): 2363-2391 [Pubmed]
Ko l ile k as LF, T r ia nta f il li d o u C, Vret to s I, G k i ka s V, Go u nar i P , Kalo me n id i s I,
M a na li E D, N a ko p o ulo u L, P ap iri s S A.
What Is Your Diagnosis? Diffuse alveolar
infiltrates and macroscopic haematuria: a r u n -a nd - g u n affair. Respiration 2010; 79(6): 511-515
[Pubmed]
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17. Manali ED, Stathopoulos G, Gildea TR, Fleming P, Thornton J, Xu M, Papiris S, Mehta AC,
Mughal MM. High Dose Rate Endobronchial Radiotherapy for Proximal Airway Obstruction due
to Lung Cancer: Eight-Year Experience of a Referral Center. Cancer Biotherapy and
Radiopharmaceuticals 2010; 25(2):207-213 [Pubmed]
18. Manali ED, Lyberopoulos P, Triantafillidou C, Kolilekas LF, Sotiropoulou C, Milic-Emili J,
Roussos C, Papiris SA .The Medical Research Council dyspnea score: relationships with
cardiopulmonary exercise test and 6-minute walk test in idiopathic pulmonary fibrosis patients: a
prospective study. BMC Pulm Med 2010; 10:32 [Pubmed]
19. Papiris SA, Triantafillidou C, Kolilekas LF, Markoulaki D, Manali ED. Lung Amiodarone:
Effects and Toxicity: A review Drugs Saf 2010; 33(7): 539-558
20. Papiris S, Manali E, Kolilekas L, Kagouridis K, Triantafillidou C, Tsangaris I, Roussos C.
Clinical review:Idiopathic Pulmonary Fibrosis Acute Exacerbations: Unravelling Ariadne’s
thread. Crit Care 2010; 14(6):246 [Pubmed]
21. Triantafillidou C, Manali ED, Magkou C, Kolilekas L, Kagouridis K, Sotiropoulou C,
Rontogianni D, Papiris SA. The prognostic significance of fibroblastic foci in idiopathic
pulmonary fibrosis. Diagn Pathol 2011; 6:28 [Pubmed]
22. Manali ED, Moschos C, Triantafillidou C, Kollintza A, Kotanidou A , Psallidas I, Karabela S,
Roussos Ch., Papiris SA, Armaganidis A, Stathopoulos GT, Maniatis N. Static and dynamic
mechanics of the murine lung after intratracheal bleomycin BMC Pulm Med 2011; 11:33
[Pubmed]
23. SA Papiris, ED.Manali, L. Kolilekas, Ch. Triantafillidou, I. Tsangaris, K. Kagouridis. Steroids in
Idiopathic Pulmonary Fibrosis acute exacerbation: defenders or killers? AJRCCM 2012; 185(5):
587-588 Letter to the Editor
24. Papiris SA, Kagouridis K, Kolilekas K, Triantafillidou C, Tsangaris I, Manali ED. Pirfenidone
treatment in idiopathic pulmonary fibrosis: too much of a great expectation. Eur Respir J 2012;
40(3): 794-795
25. Papiris SA, Triantafillidou C, Manali ED, Kolilekas L, Baou K, Kagouridis K, Bouros D.
Combined pulmonary fibrosis and emphysema. Expert Rev Respir Med 2013; 7(1): 19-32
26. Cholidou K, Kostakis ID, Manali ED, Perrea D, Margeli A, Vougas K, Markozannes E,
Koulouris N, Alchanatis M. Calprotectin: a protein related to cardiovascular risk in adult patients
with obstructive sleep apnea. Cytokine 2013 Jan 29
27. Diamanti C, Manali E, Gineri-Coccosis M, Vougas K, Cholidou K, Markozannes E, Bakakos P,
Liappas I, Alchanatis M. Depression, physical activity, energy consumption and quality of life in
obstructive sleep apnea patients before and after CPAP treatment. Sleep breath 2013 Feb 9
28. L.Kolilekas*, E.Manali*, KA Vlami, P.Lyberopoulos, C.Triantafillidou, K.Kagouridis, K.Baou,
S.Gyftopoulos, KN Vougas, A.Karakatsani, M.Alchanatis, SA Papiris. Sleep oxygen desaturation
predicts survival in idiopathic pulmonary fibrosis. J Clin Sleep Med 2013 * equally contributed
ORIGINAL ARTICLES IN INTERNATIONAL MEDICAL JOURNALS (NOT INCLUDED IN
PUBMED)
1.
Manali E, Karagiannidis N, Polychronopoulos V. Malignant Fibrous Histiocytoma with Lung
Metastases. J Bronchol 1998; 5(3): 269-270
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Choure A, Manali ED, Krizmanich G, Gildea T, Mehta AC. High price of Bronchoscopy, cost of
maintenance and repair of flexible bronchoscopes. Journal of Bronchology 2005 (Jul); 12(3):
147-150
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ARTICLES SUBMITTED FOR PEER REVIEW.
1. Kolilekas LF, Manali ED,Triantafillidou C, Papadopoulou A, Chamogeorgakis T, Peppa M,
Rontogianni D, Karakatsani A and Papiris SA. Usual interstitial pneumonia associated with celiac
disease and polyglandular syndrome type IIIA.(submitted)
2. Christina Triantafillidou*, Effrosyni Manali*, Panagiotis Lyberopoulos, Likourgos Kolilekas,
Konstantinos Kagouridis, Sotirios Gyftopoulos, Konstantinos Vougas, Anastasia Kotanidou,
Manos Alchanatis, Anna Karakatsani and Spyros A Papiris. The integration of oxygen
consumption and diffusion capacity predicts survival in IPF. [equally contributed] submitted
3. Papiris SA, Malagari K, Manali ED, Kolilekas L, Triantafillidou Ch, Baou K, Rontogianni D,
Bouros D, Kagouridis K. Bronchiolitis. Submitted
4. Kolilekas Likurgos, Manali Effrosyni, Lyberopoulos Panagiotis, Vlami Katerina, Triantafillidou
Christina, Kagouridis Konstantinos, Gyftopoulos Sotirios, Vougas Konstantinos, Karakatsani
Anna, Alchanatis Manos, Papiris Spyros. Heart rate recovery after cardiopulmonary exercise in
the estimation of survival in comorbid IPF and obstructive sleep apnea. Submitted
5. Kyriaki G. Cholidou, Effrosyni D. Manali, Ioannis D. Kostakis, Konstantinos Vougas, Evaggelos
Markozannes, Ioannis Vogiatzis, Petros Bakakos, Nikolaos Koulouris, Manos Alchanatis, MD.
The six minute walking test: a cost- effective alternative to cycle ergometry in estimation of Heart
Rate Recovery in patients with obstructive sleep apnea. The effect of CPAP treatment.
(Submitted)
CHAPTERS IN MEDICAL BOOKS
1. Papiris SA, Manali ED, Roussos Ch. Palliation of dyspnea in the terminally ill patient with lung
cancer. In Syrigos N, Nutting C, Roussos C (eds). Tumors of the Chest. 2006 Springer-Verlag
pp 575-579 ISBN 3-540-31039
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ANNOUNCEMENTS IN GREEK MEDICAL CONGRESSES (49)
GREEK REVIEW ARTICLES AND CHAPTERS IN MEDICAL BOOKS (21)
ORIGINAL ARTICLES IN GREEK MEDICAL JOURNALS (7)
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