Στυλιανή Φιδάνη

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Συνοπτικό βιογραφικό σημείωμα

Ονοματεπώνυμο

Στυλιανή (Λιάνα) Φιδάνη

Παρούσα θέση

Αναπληρώτρια Καθηγήτρια Ιατρική Βιολογία-Ιατρική Γενετική,

Εργαστήριο Ιατρικής Βιολογίας-Γενετικής, Ιατρική Σχολή Α.Π.Θ.

Β’ Παιδιατρική Κλινική, Νοσοκομείο ΑΧΕΠΑ, Θεσσαλονίκη

Προπτυχιακοί τίτλοι σπουδών

Πτυχίο Βιολογίας, Τμήμα Βιολογίας, Φυσικομαθηματική Σχολή Α.Π.Θ. (1989)

Πτυχίο Ιατρικής, Ιατρική Σχολή Α.Π.Θ. (1996)

Μεταπτυχιακοί τίτλοι σπουδών

PhD, St. Mary’s Hospital Medical School, Imperial College of Science, Technology and Medicine,

London, U.K. (1993)

Ιατρική Ειδικότητα Παιδιατρικής (2007)

Μετεκπαιδεύσεις

1. Cold Spring Harbor, U.S.A., Ιούλιος 1990. Genetic approaches to human disease using DNA markers

2. Human Genome Mapping Project, Northwick Park Hospital, Middlessex, U.K., Απρίλιος 1992

3. Neurogenetics Laboratory, Mayo Clinic, Jacksonville, Florida, U.S.A., Ιούνιος 2001

4. Institute of Neurology University of London UK, Αύγουστος 2008

Κλινικό έργο- Εξωτερικά ιατρεία

Ιατρείο Νευρομυικών παθήσεων -Νοσοκομείο ΑΧΕΠΑ Θεσσαλονίκη

Ιατρείο Γενετικής συμβουλευτικής -Νοσοκομείο ΑΧΕΠΑ Θεσσαλονίκη

M έλος Επιστημονικών Εταιρειών

Ιατρική Εταιρεία Β. Ελλάδος

Παιδιατρική Εταιρεία Β. Ελλάδος

Ελληνική Εταιρεία Ιατρικής Γενετικής

European Human Genetics Society

Κρίσεις σε Διεθνή Επιστημονικά Περιοδικά και Βιβλία

Journal of Neurological Science

Neuroscience Letters

Νeurobiology of Aging

European Journal of Neurology

Journal of Medical Genetics (Neuropsychiatric Genetics)

Canadian Journal of Physiology and Pharmacology

Fertility and Sterility

BMC Neuroscience

Εθνικές και Διεθνείς Διακρίσεις

Υποτροφία ΝΑΤΟ για εκπόνηση διδακτορικής διατριβής (1989-1992)

Α’ Χωρέμειο Έπαθλο της Ελληνικής Παιδιατρικής Εταιρείας, 27 Μαΐου 2007

Δημοσιεύσεις σε Διεθνή περιοδικά

1. Α. Goate, MC.Chartier-Harlin, M.Mullan, J.Brown, F.Crawford, L.Fidani

, L.Giuffra,

A.Haynes, N.Irving, L.James, R.Mant, P.Newton, K.Rooke, P.Roques, C.Talbot, M.Pericak-

Vance, A.Roses, R.Williamson, M.Rossor, M.Owen, J.Hardy. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer ’s disease. Nature

349, 704-706, 1991

2. F.Crawford, J.Hardy, M.Mullan, A.Goate, D.Hughes, L.Fidani

, P.Roques, M.Rossor,

MC.Chartier-Harlin. Sequencing of exons 16 and 17 of the β-amyloid precursor protein gene in 14 families with early onset Alzheimer’s disease fails to reveal mutations in the βamyloid sequence.

Neuroscience Letters 133, 1-2, 1991

3. MC.Chartier-Harlin, F.Crawford, H.Houlden, A.Warren, D.Hughes, L.Fidani

A.Goate,

M.Rossor, P.Roques, J.Hardy, M.Mullan. Earlyonset Alzheimer’s disease caused by mutations at codon 717 of the β-amyloid precursor protein gene.

Nature 353, 844-846,

1991

4. L.Fidani

, K.Rooke, MC.Chartier-Harlin, D.Hughes, R.Tanzi, M.Mullan, P.Roques,

M.Rossor, J.Hardy, A.Goate. Screening for mutations in the open reading frame and promoter of the β-amyloid precursor protein gene in familial Alzheimer’s disease: identification of a further family with APP717 Val

Ile. Human Molecular Genetics 1, 165-

168, 1992

5. K.Rooke, A.Goate, L.Fidani

, M.Mullan, P.Roques, M.Rossor, J.Hardy, MC.Chartier-Harlin.

Screening of the promoter and the β-amyloid sequence of the APP gene for polymorphism in families with late onset Alzheimer’s disease.

Neurodegeneration 1, 237-240, 1992

6. M.Mullan, H.Houlden, M.Windelspecht, L.Fidani

, C.Lombardi, P.Diaz, M.Rossor, R.Crook,

J.Hardy, K.Duff, F.Crawford. Α locus for familial early-onset Alzheimer’s disease on the long arm of chromosome 14, proximal to the a1-antichymotrypsin gene.

Nature Genetics 2,

340-342, 1992

7. L.Fidani

, J.Hardy. Chromosome 21 and amyloid plaque proteins in Alzheimer’s disease: genetic factors and molecular biology. Medicographia 15, 30-33, 1993

8. R.Adroer, C.Lopez-Acedo, R.Oliva, J.Hardy, L.Fidani. A novel silent variant at codon 711 and a variant at codon 708 of APP sequence detected in Spanish Alzheimer and control cases. Neuroscience Letters 150, 33-34, 1993

9. J.Brown, S.Gydesen, SA.Sorensen, A.Brun, K.Duff, H.Houlden, L.Fidani

, S.Kullkarni,

J.Cummings, A.Goate, M.Rossor, J.Hardy Exclusion mapping in familial Non-Specific

Dementia.

Dementia 4, 163-166, 1993

10. A. Antoniadis, S.Alexiou-Daniel , L.Fidani

, E.F.K.Bautz. Comparison of the clinical and serologic diagnosis of haemorrhagic fever with renal syndrome (HFRS) and leptospirosis.

European Journal of Epidemiology 11, 91-92, 1994

11. J.Brown, P.L.Lantos, P.Roques, L.Fidani

, M.N.Rossor. Familial dementia with swollen achromatic and corticobasal inclusion bodies: a clinical and pathological study. Journal of

Neurological Sciences 135, 21-30, 1996

12. F. Athanassiadou, D.Catriu, M. Hatzistilianou, T.Papageorgiou, S.Fidani. Effect of GM-CSF on TNF-a, IL-3 and Il-7 levels in vitro and in vivo in children with acute lymphoblastic leukaemia (ALL). Haema 2, 139-144, 1999

13. M.Hatzistilianou, L.Fidani

, F.Athanassiadou, T. Papageorgiou, D.Catriu. Identification of t(12;21) and minimal residual disease detection using RT-PCR in childhood B-lineage ALL.

Haema 3, 233-235, 2000

14. F. Athanassiadou, L.Fidani

, Th. Papageorgiou, M. Hatzistilianou, D.Catriu. Acute lymphoblastic leukaemia and urticaria pigmentosa.

Medical and Pediatric Oncology 34,

368-369, 2000

15. L.Fidani

, D. Compton, J. Hardy, R.C. Petersen, E Tangalos, V. Mirtsou, A. Goulas, F.

Wavrant De Vrieze. No association between the lipoprotein lipase S447X polymorphism and Alzheimer’s disease.

Neuroscience Letters 322, 192-194, 2002

16. L. Fidani , A. Goulas, V. Mirtsou, R. Petersen, E. Tangalos, R. Crook, J. Hardy.

Interleukin-

1A polymorphism is not associated with late onset Alzheimer’s disease.

Neuroscience

Letters 323, 81-83, 2002.

17. A. Goulas, L. Fidani , A. Kotsis, V. Mirtsou, R.C. Petersen, E Tangalos, J. Hardy. An association study of a functional catalase gene polymorphism, -262C

T, and patients with

Alzheimer ’s disease. Neuroscience Letters 330, 210-212, 2002.

18. F. Athanassiadou, L. Fidani , A. Stefanidis, G. Karkavelas, T. Papageorgiou. Giant cell tumor of the rib in a 12 year-old girl: a case report.

Pediatric Hematology and Oncology 20,

351-355, 2003

19. L. Fidani , A. Goulas, R. Crook, R. Petersen, E. Tangalos, A. Kotsis, J. Hardy. An association study of the cholesteryl ester transfer protein TaqI B polymorphism with late onset Alzheimer’s disease. Neuroscience Letters 357, 152-154, 2004

20. L. Fidani , F. Athanassiadou-Piperopoulou, A. Goulas, K. Chatzidakis, D. Koliouskas, A.

Kotsis. An association study of the tumor necrosis factor alpha C-850T polymorphism and childhood acute lymphoblastic leukemia in a population from northern Greece. Leukemia

Research 28, 1053-1055, 2004

21. L. Fidani , A. I. Hatzitolios, A. Goulas, C. Savopoulos, C. Basayannis, A. Kotsis.

Cholesteryl ester transfer protein TaqI B and lipoprotein lipase Ser447Ter gene polymorphisms are not associated with ischaemic stroke in Greek patients. Neuroscience

Letters 384, 102-105, 2005

22. K. Chatzidakis, A.Goulas, F.Athanassiadou-Piperopoulou, L. Fidani , D. Koliouskas, V.

Mirtsou. Methylenetetrahydrofolate reductase C677T polymorphism: Association with risk for childhood acute lymphoblastic leukemia and response during the initial phase of chemotherapy in Greek patients. Pediatric Blood and Cancer 47, 147-151, 2006

23. L. Fidani , K. Kalinderi, S. Bostantjopoulou, J. Clarimon, A. Goulas, Z. Katsarou, J. Hardy,

A. Kotsis. Association of the Tau haplotype with Parkinson's disease in the Greek population.

Movement Disorders 21, 1036-1039, 2006

24. L. Fidani , J. Clarimon, A. Goulas, A. I. Hatzitolios, W. Evans, E. Tsirogianni, J. Hardy, A.

Kotsis. Association of phosphodiesterase 4D gene G0 haplotype and ischaemic stroke in a

Greek population. European Journal of Neurology 14, 745-749, 2007

25. K. Kalinderi, L. Fidani , S. Bostantjopoulou, Z. Katsarou, A. Kotsis. The G2019S LRRK2 mutation is uncommon amongst Greek patients with sporadic Parkinson’s disease.

European Journal of Neurology 14, 1088-1090, 2007

26. A. Goulas, M. Kosmidou, A.I. Hatzitolios, N. Raikos, D. Molyva, C. Savopoulos, S.

Giannopoulos, L. Fidani. An association study of sodium – lithium countertransport activity with glutathione S transferase (GST) T1 and GST M1 null polymorphisms in Greek dyslipidaemic patients and controls.

Clinical Chemistry and Laboratory Medicine 46, 306-

310, 2008

27. A. Goulas, M. Kosmidou, A.I. Hatzitolios, D. Molyva, L. Fidani , S. Giannopoulos, V.

Mirtsou. Glutathione S-transferase null and cholesteryl ester transfer protein TaqI B

polymorphisms and lipid response to atorvastatin in Greek dyslipidaemic patients.

Basic and Clinical Pharmacology and Toxicology 2008, E-pub ahead of print (doi: 10.1111/j.1742-

7843.2008.00220.x)

28. A. Tragiannidis, G. Tzouvelekis, M. Eboriadou, L. Fidani , E. Pavlou, T.Papageorgiou, F.

Athanassiadou. Septic pulmonary embolism due to staphylococcus aureus. Pediatrics

International 2008, in press

29. K. Kalinderi, L. Fidani , S. Bostantjopoulou. From 1997 to 2007: a decade journey through the H1 haplotype on 17q21 chromosome. Parkinsonism & Related Disorders 2008, in press

30. K. Kalinderi, L. Fidani , G. Kourtesi, Z. Katsarou, E. Mioglou, S. Bostantjopoulou. No association of the Val158Met COMT polymorphism with Parkinson’s Disease in the Greek population. European Journal of Neurology 2008, 15(8):83

31. Κ. Kalinderi, S. Bostanjopoulou, C. Paisan-Ruiz, Z. Katsarou, J. Hardy , L.Fidani Complete screening for glucocerebrosidase mutations in Parkinson disease patients from Greece

Neuroscience Letters 2009, 452:87-89

32. A.Xanthis, A. Hatzitolios, S.Fidani

, C.Befani, G.Giannakoulas, G. Koliakos. Receptor of advanced glycation end products (RAGE) positively regulates CD36 expression and reactive oxygen species production in human monocytes in diabetes. Angiology 2009,

33. Kalinderi K., Fidani L., Katsarou Z., Clarimon J., Bostanjopoulou S., Kotsis A. GSK3beta polymorphisms MAPTH1 haplotype and Parkinson’s disease in a Greek cohort.

Neurobiology of Aging 2011 32(3) 546e1-5

34. Dimitriadou M., Christoforidis A., Economou M., Tsatra I., Vlachaki E., Fidani L ., Katzos G.,

Athanassiou-Metaxa M. Elevated serum parathormone levels are associated with myocardial iron overload in patients with beta-thalassaemia major. Eur. J. Haematol. 2010

1;84(1) 64-71

35. Dimitriadou M, Christoforidis A, Fidani L, Economou M, Perifanis V, Tsatra I, Katzos G,

Athanassiou-Metaxa M. Hematology. 2011 Jan;16(1):54-8.

36. Dimitriadou M. et al. Pediatr. Hematol. Oncol. 2011 28(6): 509-516

37. Karakasis C. et al. J. Clin. Neuroscience 2011 18(12): 1744-5

38. Kalinderi K. et al. Int.J.Clin. Pract. 2011 65(12) ¨1289-94

39. Kalinderi K. et al. Genetic Testing and Molecular Biomarkers 2012:974-7

40. Kalinderi et al. Neurosci Lett 2013 541:190-2

41. Kara E. Et al. Neurobiol. Aging 2014 35(2)

Total number of citations (May 2011) : 3857, H-index : 10, Impact factor : 147.087

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