Erica Baruch Bio Final Definitions Kilo=1000 Deci=1/10 Centi=1/100 Milli=1/1000 Micro=1/1000000 Nano=1000000000 Diaphragm=controls the amount of light entering the microscope Stage=supports slide Stage Clips=holds glass slide specimen in place Revolving Nosepiece=directs light into scope Eyepiece=on the revolving nosepiece and contains a lens capable of 10x magnification Protons=positively charged particles Neutrons=neutral particles Electrons=subatomic negatively charged particles outside the nucleus Atomic Number=number of protons in the nucleus identity of the atom Atomic Mass=protons + neutrons Ions=charged atomsthe number of protons and electrons are different Elements=substances composed of the same atoms -Same number of protons -Same numbers of protons as neutrons -Mass Number=average of isotopes Isotopes=atoms with varying numbers of neutrons but the same number of protons -Different mass number -Same chemical properties and same atomic number -Isotope of Hydrogen: Name Atomic # Mass # Protons Electrons Neutrons Protium 1 1 1 1 0 Deutorium 1 2 1 1 1 Tritium 1 3 1 1 2 Non-Radioactive=stable nucleus Radioactive=unstable nucleusunbalanced protons and neutrons Treatment of diseases, radioactive dating, sterilization of food, study of organisms Electron Configuration=288 Valence Electrons=electrons on the outermost level Unstable Atom=outermost level (valence) is not full Ionic Bonding=losing/gaining electrons because there is an attraction between oppositely charged ions Covalent Bonding=sharing electrons the bond provides stability Element Electrons Valence Missing Hydrogen 1 1 1 Oxygen 8 6 2 Nitrogen 7 5 3 Carbon 6 4 4 Chlorine 17 7 1 Polar=electrons attract to one element more than the other because of varied numbers of elections when there are 2 different signs Electronegativity=tendency to attract electrons H2O: there is OH- and H+ so there is a slight negativity dissolves charged things pH=potential hydrogen concentration of H+ and OH- ions Acids=very reactive compounds with H+ ions floating around when dissolved in water pH=less than 7 Bases=very reactive compounds with OH- ions floating around when dissolved in water pH=more than 7 Phenol Phthalin=base indicator turns substance pink when OH- ions are present Organic Compounds=have both carbon and hydrogen Inorganic Compounds=don’t have both carbon and hydrogen (CO2, H2O, NaCl, HCl) Monomer=small molecule O Polymer=repeating molecules with covalent bonds O-O-O-O-O Dehydration Synthesis=joining of monomers with covalent bonds when H2O breaks off Hydrolysis=breaking of covalent bonds in monomers when H2O breaks: the OH- goes to one monomer and the H+ goes to the other monomer Carbohydrates=oxygen, hydrogen, and carbon FUNCTION=energy and structural support Monosaccharide=one simple sugar covalently bonded with dehydration synthesis * Function=energy for cells C6H12O6 Glucose=hexagon structure -Photosynthesis=turns sun energy into chemical energy Light + 6H2O + 6CO2 C6H12O6 + 6O2 Fructose=pentagon structure Galactose=hexagon structure Disaccharide=two simple sugars covalently bonded with dehydration synthesis FUNCTION=provides energy 2C6H12O6 C12H22O11 + H2O (one O and 2 H break off) Sucrose=glucose + fructose Lactose=glucose + galactose Maltose=glucose + glucose Polysaccharide=many simple sugars covalently bonded with dehydration synthesis Starch / Glycogen=chain of glucose molecules FUNCTION=reservoir for glucose and energy -Starch is only in animals but when we eat it, it gets turned into glucose (hydrolysis), which gives energy to cells and is then turned into glycogen (dehydration synthesis) and is stored Starch Glucose Glycogen D.S. H Cellulose=chain of glucose molecules FUNCTION=structural support and makes up cell wall in plants -Only in plants and people/animals can’t digest it: cows can eat it because they have microorganisms that digest it to get the glucose Chitin FUNCTION=structural support and endoskeleton of spiders and crustation -In some animals—crustation: insects, crabs, shellfish, etc. Benedicts=indicates monosaccharides (blueflashy orange) Iodine=indicates polysaccharides (yellowvery dark blue) Lipids=fats and oils Structure=one glycerol (E) and 3 fatty acids (6 sac line) Glycerol=carbon, OH, and hydrogen Fatty Acid=carboxyl group and a chain of carbon and hydrogen **When the fatty acid and glycerol bond 3H2O break off (from each fatty acid) so there is no more carboxyl group Fats=only in animals FUNCTION=cushions organs, provides and stores energy, and insulates against cold Saturated Fatty Acids=fatty acids only have single bonds Oils=plant seed embryo only in plants FUNCTION=provide energy for plant seed embryo Unsaturated Fatty Acids=fatty acids have double bonds Phospholipids=one glycerol 2 fatty acids and a phosphate group (P) FUNCTION=building block of cell membrane -The fatty acids are hydrophobic and the phosphate group is hydrophilic Steroids=hormones and cholesterol * Structure=all unstable carbons Hormones Estrogen Testosterone Adrenalin HGH (for migits) Cholesterol=building block of cell membrane in animals Proteins=chains of amino acids (monomers) Structure=amino group, acid/carboxyl group, carbon, hydrogen, R group Amino Group=H--N, H (left) Acid/Carboxyl Group=O--C--OH Carbon=double bond R=variable for 20 different types of amino acids Peptide Bond=bond between amino acids with dehydration synthesis where H2O breaks off Dipeptide Bond=2 amino acids joined together with a peptide bond Polypeptide Bond=proteinmany amino acids bonded with peptide bonds Primary Structure= Secondary Structure=amino acids coil up into a spiral **It is polar because there are different numbers of protons positive Tertiary Structure=the spiral folds into a coiled ball because there isn’t enough space for it to stretch out -The folding is not random: proteins each have their own type of folding **Not all proteins have this structure--some remain in secondary Structural Proteins=hair, skin, ligaments, nails (layered coils) -Remain in secondary structure Globular/Functional Proteins=enzymes, hormones, antibodies -Tertiary structure Nucleic Acids=DNA, RNA, ATP Structure=phosphate group, monosaccharide, nitrogenous base Nucleotide=monomer of nucleic acids DNA=deoxyribonucleic acid 2 strands of nucleotides FUNCTION=carries genetic code and determines protein structure RNA=ribonucleic acid 1 strand of nucleotides FUNCTION=protein synthesis ATP=adenosine triphosphate Single nucleotide FUNCTION=provides energy for cells Humans=46 chromosomes -25,000 genes -3 billion nucleotides -Regulatory DNA Regions=turn on/off genes before start codons Blood Types=depends on proteins A / B (and red blood cells) Type Antibodies A A I I =type A against B A B I I =type AB universal recipient IBIB=type B against A A I i=type A against B B I i=type B against A ii=type O against A and B universal donor A Alleles: I =protein A IB=protein B i=no A or B ** Antibodies fight against the other blood and clump together to form a blood clot Human Genetic Disorders=mutations Autosomal Recessive=only on homozygous recessive genotype (tt) and not sex chromosomes Tay-Sacks Disease=brain deterioration 3-5 years of life expectancy TT x Tt 50% TT Tt x Tt 25% tt 50% Tt 100% NOT tt PKU=enzyme for processing phenylalanine (amino acid) is missing/not function so it accumulates in brain cells -Treatment=avoiding phenylalanine by eating specific foods Cystic Fibrosis=protein channel mutation so there is an excess of mucus from the lungs and digestive system short life expectancy once it breaks out Autosomal Dominant=only on homozygous dominant (DD/Dd) Huntington’s Disease=brain deterioration later in life (30s) -It changes the mood to angry/aggressive/crazy retarded medical vegetable **Very rare DD x dd 100% Dd Dd x dd 50% Dd Sex Linked Disorders=mutations on sex chromosome Recessive on X=more common in males X1=disorder X=normal Woman: XX=normal X1X=carrier but normal X1X1=disorder 1 Man: X Y=disease XY=normal X1 X X1X XX X X1Y XY Y 1 XY x X X 25% child 50% boy 0% girl -Color Blindness=sex linked -Hemophilia=disease where blood clots don’t work well and clotting factors are missing Chromosomal Disorders=extra/missing chromosome (or a piece of the chromosome) Non Disjunction in Meiosis=the homologous chromosomes don’t split equally so there is an extra or missing chromosome **Only one set (tetrad) is affected so there are 23 chromosomes Down Syndrome=chromosome 21 has 3 instead of 2 Klinefelter Syndrome=XXY male with underdeveloped sex organs Turner Syndrome=XO female with underdeveloped sex organs but lives a normal life Cry of the Cat=lack of chromosome 5 -Not normal: makes weird sounds and is retarded Detection of Genetic Disorders Pedigree=family tree = male = female = disorder Shaded=disorder Half shaded=carrier Genetic Testing=detection of mutated genes -They need the gene to know what they are looking forthey heat the DNA so it separates and they copy the DNA by adding nucleotides and DNA polymerase PCR=using fractions of genes and copying them to test -They use a probe to see if the DNA with the disease matches up to the person’s DNA Analysis of Chromosomes Karyotyping=analyze nucleus after mitosis so they are uncoiled and visible and look if there is anything missing or extra Amniocentesis=they test the fluids in the embryo stage (amniotic sac) ** Recommended for older women because down syndrome is more common Nonliving Organisms Viruses=no cells, life activities, or chemical reactions Retro Virus=DNA or RNA Lytic Cycle=inject DNA into the cells and take it over so it reproduces viruses and then explodes so the viruses spread in the body (1 hour long process) Lysogenic Cycle=after the injection the DNA remains dormant in the cell and gets replicated if the cell divides gets active Lytic Cycle begins -Viral Diseases=cold, stomach virus, hepatitis (liver) no antibiotics for viral Aids=acquired immune deficiency syndrome -Caused by HIV (human immune virus) that you catch -It breaks out and paralyzes the immune system because it infects white blood cells -It gets into the body from body fluid: breast milk, urine, saliva, blood, vaginal fluid, sperm Sexual intercourse STD Blood transfusions Sharing needles of drug addicts -Treatment=many pills and medication but VERY expensive Ebola=inner organ bleeding die within days Herpes=cold sores virus hides in cells forever and become active a few times a year Genital herpescold sores on genitals Prions=only in animals – short proteins that multiply in cells Mad Cow Disease OR Crentfeldt Jacob Disease prions multiply in brain cells and destroy the brain Virods=short/circular RNA molecules that cause certain diseases by using cells to multiply -only in plants Living Organisms Old System: 2 domains=Prokarya and Eukarya 5 kingdoms=monera protista, fungi, plantae, animalia New System: 3 domains=Prokarya Eubacteria / Archaea and Eukarya 6 kingdoms=eubacteria / archaea bacteria protista, fungi, plantae, animalia Domain Eubacteri Achaea a Eukarya Archaea Protists Fungi Plants Bacteria Cell Type Prokaryotic Eukaryotic Number of Most Most Unicellular Mulitcellular Unicellular Multicellular Cells Peptidoglyco Some of Protein Chitin Cellulose Cell Wall gen cellulose consumer consumer producer Nutrition E.Coli Thermophils Ameba Para Example homosapiens live in hot mecia Eugle -cause conditions na Algae Kingdom Eubacteria Animals consumer tuberculoses Holophils li ve in salty conditions Methaneog ens produce methane Eubacteria=prokaryotic Cell wall (protein and carbohydrate) Reproduction=splits into 2 Binary Fission=DNA replication When the cell grows the DNA separate to the sides of the cells Endospores=if the conditions are unfavorable the bacteria shrivel up and covers itself in a thick shell so it can remain without water for a long time and when there is food it grows back -Mutualists: most help -Decomposers: can’t exist without them -Parasites=off everything -Cholera=in dirty water -Salmonella=eggs -Bubonic Plague -Tuberculosis -Getting rid of bacteria: chemicals, radiation/rays, heat Protists=dumping ground for everything Unicellular Multicellular Plant Like Autotrophs -Volvox -Euglena Animals Like Green Algae=plant ancestor bound to water except lichen live on land Red Algae Fungi=many hyphae (cells put together) mycelium is the way fungi grow -Athletes foot grows hyphae into skin PAGE PAGE 1