Summer 2009 CHML211 10am Sections REQUIRED TEXTS: CHML 211-212 Laboratory Manual for Organic Chemistry (Fall 2008 Edition) Organic Chemistry Laboratory Notebook ***ALL STUDENTS MUST SUPPLY THEIR OWN SAFETY GLASSES!*** COURSE WEBSITE: http://www.uncw.edu/chem/courses/chmL211/ TENTATIVE SCHEDULE Date: 5/14 EXP. # *** 5/18 5/20 5/21 5/25 5/27 5/28 6/1 6/3 6/4 6/8 6/10 6/11 6/15 1 2 4 *** 3 5 6 7 8 9 10 12 11 EXPERIMENT TITLE Intro to Laboratory: Lab Safety and Data Maintenance Structure, Intermolecular Forces, and Solubility Distillation and Gas Chromatography of Alkanes TLC and HPLC of Nitroanilines NO LAB—MEMORIAL DAY HOLIDAY Stereochemistry and Molecular Modeling Test 1 (Exps. 1,2,4) Column Chromatographic Separation of Nitroanilines Extraction of Analgesics Recrystallization, Melting Point, and HPLC Analysis of Analgesics Bromination of Stilbene: A Green Chemistry Synthesis Properties of Stereoisomers of Menthol Test 2 (Exps. 3,5,6,7,8) Acid-Catalyzed Dehydration of an Alcohol with Rearrangement Base Promoted Elimination of HBr from an Alkyl Halide Conversion of an Alcohol to an Alkyl Bromide with Rearrangement Test 3 (Exps. 9,10,11,12) Course Grading and Policies 93-100 = A, 90-92 = A-, 87-89 = B+, 83-86 = B, 80-82 = B-, 77-79 = C+, 73-76 = C, 70-72 = C-, 67-69 = D+, 63-66 = D, 60-62 = D-, <60 = F. Attendance and Safety: No one is admitted to lab after the first 10 minutes or without close-toed shoes, lab manual, or safety glasses. You are expected to attend every laboratory session. There are NO make-up labs. You will receive a 0 for every lab you do not attend, regardless of the reason for the absence. If you miss three or more labs (including those for which you were more than 10 minutes late) you will receive a grade of "F" for the entire course. Your lowest lab report grade is dropped at the end of the semester. Lab Exams (50%): 3 lab tests will be given, testing on 3-5 experiments each. Test dates are given on syllabus. Study guides will be provided on the course website. There will be NO make-up exams. Lab Reports/Lab Notebook/Technique (50%): Laboratory Notebook (~20%) Your notebook will consist of pre-lab and in-lab entries as described in class and in Appendix C in the lab manual. A list of notebook requirements for each experiment is provided on the course website. Yellow carbon pages containing pre-lab notebook entries will be due at the beginning of each lab period. Yellow carbon pages containing in-lab entries from BOTH students must be submitted before leaving lab for the day. Laboratory Reports (~20%) Each lab group will submit ONE copy of the final lab report. Lab reports are due 24 hours after the completion of the laboratory experiment. Late lab reports will receive a penalty of 5% of total grade per day. Unless previously arranged with instructor, once graded lab reports are returned to students, no more lab reports will be accepted. Lab Technique (~10%) Up to 10% of the final grade for each experiment will be based on technique. In order to receive the maximum score on the technique portion of your grade, you must do the following: Keep up with the glassware from your lab drawer. Return it to the lab drawer clean and dry, as well as to the drawer from which it came. Keep your work area clean and clean up after yourself. Equipment cords must be unplugged, wrapped, and the equipment pushed to the back of the hood before leaving. Bring your own safety goggles and wear them at all times while in the lab. Come to lab prepared to do an experiment, having prelab completed, and ready to participate in the experiment. Write things down in your lab notebook as you do the experiment. Be sure to submit samples to instructor when required. This applies to samples for instrumental analysis and samples for storage. If you throw out your samples too early, you will not have all of the results needed to complete an assignment. Turn in materials on time. Be safe! Be familiar with the hazards of the chemicals to be used during an experiment. Obey your safety contract at all times! Special Concerns Federal Americans with Disabilities Act: If you have a disability and need reasonable accommodation in order to participate fully in this course, you should inform the instructor of this fact in writing within the first week of class or as soon as possible. If you have not already done so, you must register with the Office of Disability Services in Westside Hall and obtain a copy of your Accommodations Letter. You should then meet with your instructor to make mutually agreeable arrangements based on the recommendations of the Accommodations Letter. Health Concerns: If you have any existing physical conditions that might affect your performance, your health, or other peoples' health in the lab, please inform your instructor. This information will be kept confidential; examples might include pregnancy, medications, allergies, epilepsy, AIDS. Special arrangements may be possible.