BIOL 419 – GENETICS – FALL 2008
CLASS DATE
August 22
25
27
29
September 1
3
5
8
10
12
15
17
19
22
24
26
29
October 1
3
6
8
10
13
15
17
20
22
24
27
29
31
November 3
5
7
10
12
14
17
19
21
24
26
28
December 1
3
5
8
10
CLASS AGENDA & READING ASSIGNMENT
Introduction
Chapter 1 – The Genetic approach to biology
Chapter 1 – The Genetic approach to biology
Chapter 2 – Single-gene inheritance
No class -- Labor day
Chapter 2 – Single-gene inheritance
Chapter 3 – Independent assortment of genes
Chapter 3 – Independent assortment of genes
Chapter 4 – Mapping eukaryote chromosomes by recombination
Chapter 4 – Mapping eukaryote chromosomes by recombination
Exam 1
Chapter 20 – Gene isolation and manipulation
Chapter 20 – Gene isolation and manipulation
Chapter 5- The genetics of bacteria and their viruses
Chapter 5- The genetics of bacteria and their viruses
Chapter 6- Gene interaction
Chapter 6- Gene interaction
Chapter 7- DNA: Structure and replication
Chapter 7- DNA: Structure and replication
Exam 2
Chapter 8- RNA: transcription and processing
Chapter 8- RNA: transcription and processing
Chapter 9- Proteins and their synthesis
Chapter 9- Proteins and their synthesis
No class – Fall break
Chapter 10-Regulation of gene expression in bacteria and their
viruses
Chapter 10-Regulation of gene expression in bacteria and their
viruses
Chapter 11-Regulation of gene expression in eukaryotes
Chapter 11-Regulation of gene expression in eukaryotes
Exam 3
Chapter 12-The genetic control of development
Chapter 12-The genetic control of development
Chapter 13 – Genomes and genomics
Chapter 13 – Genomes and genomics
Chapter 14 – The dynamic genome
Chapter 14 – The dynamic genome
Exam 4
Chapter 15– Mutation, repair, and recombination
Chapter 15– Mutation, repair, and recombination
Chapter 16 – Large-scale chromosomal changes
Chapter 16 – Large-scale chromosomal changes
No class – Thanksgiving Break
No class – Thanksgiving Break
Chapter 17 – Population Genetics
Chapter 17 – Population Genetics
Chapter 19 – Evolutionary genetics
Chapter 19 – Evolutionary Genetics
Exam 5
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LAB SESSION
No lab this week
Week One
DNA isolation
Week Two
No lab
This week
Week Three
DNA
restriction map
Week Four
DNA
restriction map
Week Five
DNA
restriction map
Week Six
GMO
Week Seven
GMO
Week Eight
No lab
This week
Week Nine
GMO
Week Ten
E.coli
Transformation
Week Eleven
E.coli
Transformation
Week Twelve
ELISA Assay
Week Thirteen
Protein
Fingerprinting
Week Fourteen
No lab
This week
Week Fifteen
Protein
Fingerprinting
Week Sixteen
Protein
Fingerprinting
BIOL 419 – GENETICS – FALL 2008
INSTRUCTOR
Dr. Bin Shuai
Department of Biological Sciences
Office: Hubbard Hall Room 418
Phone: 978-6142
Email: bin.shuai@wichita.edu
Office hour: MW 10:00 am – 11:00 am
GRADUATE TEACHING ASSISTANTS
Megan Simpson
Ramesh Padmanabhan
TEXTBOOK
Introduction to Genetic Analysis 9th Edition by Griffiths et.al.
ISBN: 0-7167-6887-9
Publisher: W.H. Freeman
PREREQUISITES
In order to take this course, you should already have completed Biol 210 – General Biology I,
Biol 211 – General Biology II and Chem 112 – General and Inorganic Chemistry.
EXAMINATIONS AND GRADING
All class examinations will be given during normal classroom hours on the date indicated on the
class schedule. There is no make up exam.
Grade-earning activities include lecture exams, class participation, and lab quizzes. The overall
course grade will be determined from the total points (720 points) obtained from the five class
examinations (maximum of 500 points at 100 points per exam), in-class participation (maximum
of 100 points), and the lab grade (maximum of 120 points). The overall lab grade will be based
on performance in weekly quizzes. All lecture examinations will cover the material presented
since the previous examination.
CLASS AND LABORATORY ATTENDANCE
Your attendance at each class and laboratory session is required. For the class session of the
course, you will sign in for each attendance. Three absences of lecture and one absence of lab
will be excused. After that, each absence will result in the reduction of the final course grade by
½ of a letter grade. The same policy applies for the laboratory session.
In-class participation
Each chapter will be covered in two class periods, with the first lecture given by the instructor
followed by an interactive group exercise in the second lecture. The class will be divided into 7
groups which will be determined during the first week of the class. After the first lecture for each
chapter, each group will be given a question. The group members will work together to solve the
problem, and present the solution during the class period for group exercises.
Rules for group exercises:
 Each group should have at least 8 students, and can’t have more than 12 students;
 Each student has the option to sign up into a particular group before Aug 26, 2008, the
rest will be assigned randomly into existing groups by the instructor; (The sign up sheets
will be posted outside my office at HH418);
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BIOL 419 – GENETICS – FALL 2008
 The group members should decide your meeting time and the group policies to make sure
that everyone is making a good effort in solving the problems. I will give group
members the right to vote out the student(s) who is/are not contributing to the group;
 All questions will be posted on Blackboard in advance, each group will be randomly
assigned one question;
 The group should decide who will be presenting the answer. The presenter has to show
the rest of the class how to work out the solution using appropriate visual aids (for
example, draw on the board, or use transparency etc.). The presenter and the rest of the
group should address any questions raised by the class and the instructor.
Reward: In each lecture period, the group that provides correct answer clearly will be given 10
points. Partial credit will be considered for incomplete answers. The maximum bonus points for
each group are limited to 100 points during the semester. The instructor will award the best
presenter in each class period with 5 additional bonus points. The total bonus points for each
student are limited to 20 (the bonus points are additional, not part of the 720 total points for the
class).
POLICY ON LABORATORY VOUCHER RECEIPTS
A receipt for a non-refundable laboratory voucher, which you must purchase at the RSC
Bookstore, is required to complete your enrollment in this course. The receipt must be presented
to your laboratory instructor, no later than the second laboratory meeting, in order to continue
your enrollment in this course.
POLICY ON ACADEMIC HONESTY
The Department of Biological Sciences adheres to the University Policy on Academic Honesty
as described in the Undergraduate Catalog, the Graduate Bulletin and the Student Handbook.
The penalties for breach of this policy vary with the degree of dishonesty and will be determined
by the faculty member teaching the course. Such penalties may range from reprimand to
dismissal from the University. Typical first offense penalties include, but are not limited to,
receiving a zero on an examination for cheating; receiving zero points for the laboratory portion
of the course for cheating on a laboratory examination (if there is a lab associated with the
course); or, receiving a letter grade of “F” in the course for plagiarizing material. Penalties may
be more severe in cases of repeat offenses. In all cases, a report of the violation will be placed in
the student’s permanent file in the Dean’s office of the student’s College. Students may appeal
all disciplinary actions for violations of the Policy by following the procedures of the Court of
Student Academic Appeals.
SUGGESTED STUDY PLAN FOR THE CLASS COMPONENT
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Before attending class, read the chapter in your textbook that will be covered in the class.
Make sure you understand the self study materials.
Attend the class; take notes about the topics covered by the instructor.
After class, return to the notes and ensure that you understand the concepts covered in class.
Evaluate yourselves using problems at the end of each chapter.
If you are having difficulty mastering the concepts covered, try gaining further understanding
from the following sources:
o Return to the text and review the concepts
o Make an appointment with the instructor and come prepared to ask specific questions
o Form a study group early in the semester that meets regularly during the semester
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