PRACTICE EXAM 3 – Some of this may look familiar, but the exam is different! 1. In a cell, (nuclear) DNA is enclosed in the __________. 2. Division of the nucleus, called ________________, occurs before division of the cytoplasm, called __________________________. 3. The important roles of cell division—in particular, mitosis—are _________________, ______________________, and _______________________. 4. The two parts of the cell cycle are ___________ and ___________. During the phase that takes most of the time, DNA ________________ and during the other phase it _____________________, which is necessary before the cell can divide. 5. Chromosomes are composed of ____________________, which is a mix of DNA and _____________________________. 6. Compare and contrast sister chromatids and homologous chromosomes. _____________________________________________________________________ _____________________________________________________________________ 7. In anaphase, ____________________________ and the place where they are connected (_______________) are separated by the ___________________________ to make ___ cells. The DNA made in both cells is genetically (identical/different). 8. __________________________________ control the cell cycle and thus cell growth. 9. Cancer cells are different from normal cells in that ___________________________. They are not inhibited by things normal cells are, including ____________________. 10. Mitotic reproduction is (asexual/sexual), while meiosis happens in (asexual/sexual). 11. What four things contribute to genetic variation? _____________________________ _____________________________________________ and meiosis. Describe those. _____________________________________________________________________ _____________________________________________________________________ What two mechanisms are there in meiosis that contribute to genetic variation? _____________________________________________________________________ 12. Mitosis produces ___________________________________ while meiosis produces _____________________________________________. 13. Humans have _____ pairs of homologous chromosomes, which can be seen in a special test called a ________________; each pair is genetically (identical/different), and each chromatid of each pair is genetically (identical/different). 14. Crossing over, which happens at the _____________, occurs during what phase of meiosis? ______________________ It creates ___________________ chromosomes. 15. Synapsis happens during what phase of meiosis? What is synapsis? ______________ _____________________________________________________________________ 16. During anaphase I, ___________________________ are pulled apart, which are genetically (identical/different), by microtubules attached to the ________________. 17. During anaphase II, ___________________________ are pulled apart, which are genetically (identical/different). Why are they that way? _______________________ 18. When do we see tetrads? _____________________ Dyads? ____________________ 19. After telophase II, there are 4 genetically (identical/different), (haploid/diploid) cells that are called ____________________ in humans (and other mammals). 20. When looking at the steps in each of the phases of meiosis and mitosis, what is the key difference between meiosis I and meiosis II? Mitosis and meiosis II? __________ _____________________________________________________________________ _____________________________________________________________________ 21. What errors may occur during meiosis that causes syndromes, and what are some of those syndromes? ______________________________________________________ _____________________________________________________________________ 22. The blending hypothesis predicts that ______________________________________ ___________________________________, while the particulate hypothesis predicts ____________________________________________________________________. 23. The work of _________________, who started the field of genetics, supports the (blending/particulate) hypothesis. 24. He started with the parental or (F2/P/F1) generation, cross-pollinated them, created the (F2/P/F1) generation and then self-pollinated those to create the (F2/P/F1). 25. He discovered that the F1 offspring had the (dominate/recessive) trait and that the (dominate/recessive) trait reappeared in the F2 offspring in a ________ ratio. This ratio can be demonstrated by drawing a __________________________________. 26. This lead to his belief that everyone has two “particles,” one from each parent. They are now called _______________. Each “particle” is found on one chromatid in __________________. During the phase ___________, the “particles” are separated. 27. Describe the Law of Segregation as it applies to the “particles” and to chromosomes. _____________________________________________________________________ 28. Describe the Law of Independent Assortment as it applies to the “particles” and chromosomes. ________________________________________________________ _____________________________________________________________________ 29. You are given a purple flower. Purple is its (phenotype/genotype). Since purple is a dominant trait, you perform a _____________ to determine its (phenotype/genotype). 30. T or F: If a flower is pink but its parents were red and white, it is an example of pleiotropy. 31. What is incomplete dominance? Does it support the particulate hypothesis? ________ _____________________________________________________________________ _____________________________________________________________________ 32. Compare and contrast pleiotropy and polygenic inheritance. ____________________ _____________________________________________________________________ _____________________________________________________________________ 33. Sickle cell disease is an example of _______________________________________. 34. Sutton’s Chromosome Theory of Heredity proposed that _______________________ ____________________________________________________________________. 35. Morgan did many tests on flies. He discovered wild type and mutant phenotypes. Define those. _________________________________________________________ What is a “vestigial” trait? _______________________________________________ 36. Since the mutant phenotype was found only in males, Morgan discovered _________ __________________________. How did his discovery relate to the Theory of Heredity? ____________________________________________________________ 37. What are “sex-linked” genes? How do they cause certain disorders? ______________ _____________________________________________________________________ 38. What are linked genes? Do they follow Mendel’s Law of Independent Assortment? _____________________________________________________________________ 39. A dog that is heterozygous for two traits (i.e. BbHh) mated with a dog with recessive genes (bbhh). The majority of the puppies (90%) had the phenotypes of their parents. What does this suggest about the two traits? How did some puppies NOT have the phenotypes of their parents? _____________________________________________ _____________________________________________________________________ 40. Those puppies that didn’t have either parent’s phenotype are called ___________________ offspring. 41. The probability of recombination depends on ________________________________ and is higher when ____________________________________________________. 42. What is genomic imprinting? _____________________________________________ _____________________________________________________________________ 43. Lamarck’s Theory of Evolution had two ideas. What were they? Describe them. Are either valid? __________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 44. What are Darwin’s two main ideas of his Theory of Evolution? Describe them. Are either valid? __________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 45. The environment limits the population of salmon; only some live to _____________. How does this relate to natural selection? ___________________________________ _____________________________________________________________________ 46. T or F: Natural selection leads to perfectly adapted species. 47. Natural selection acts on the (individual/population). Evolution acts on the (individual/population). Does this mean individuals can evolve? (Yes!/No!) 48. Natural selection is ____________________ to the environment. 49. T or F: Evolution always leads to more complex species and explains the origin of life on Earth. 50. Name some key evidence supporting Darwin’s theory. ________________________ _____________________________________________________________________ ____________________________________________________________________ Specifically, what is artificial selection? How does it support the theory? __________ _____________________________________________________________________ 51. We say evolution acts on the population, but what about pesticide resistance? Is that an example of an individual insect evolving? Explain. _________________________ _____________________________________________________________________ _____________________________________________________________________ 52. In microevolution, ________________—a localized group of organisms of the same species—is studied by looking at their __________________, or total composition of genes (for all time/at that time). 53. What is allelic frequency? Why do we analyze it over and over for a population? _____________________________________________________________________ 54. What does the Hardy-Weinberg theory state? Are his conditions realistic? What does his equation show? _____________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 55. There are 2 main causes for microevolution. Describe each and how it affects populations. __________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 56. In what 2 effects can genetic drift have a huge impact? Describe them. ____________ _____________________________________________________________________ _____________________________________________________________________ 57. There are 3 modes of natural selection. What are they, and when do they occur? _____________________________________________________________________ _____________________________________________________________________ 58. Sexual reproduction (increases/decreases) (phenotypic/genetic) diversity within a population. Do you know how? ___________________________________________ 59. Natural selection works on that diversity, (increasing/decreasing) (phenotypic/genetic) diversity within a population. (Do you know how?) 60. In spite of natural selection, there are 3 things that help to keep genetic diversity. What are they? ________________________________________________________ 61. _____________________, or the origin of new species, is a way of increasing ________________________________________. How does this process occur? _____________________________________________________________________ _____________________________________________________________________ 62. There are two patterns of speciation. What are they? Do both increase biological diversity? ____________________________________________________________ _____________________________________________________________________ 63. Reproductive barriers can occur within a species; these barriers can be ____________ or _____________. What are examples of each? _____________________________ _____________________________________________________________________ _____________________________________________________________________ 64. T or F: There is only one way to identify a species: the Biological Species Concept. 65. What does the biological species concept state? ______________________________ _____________________________________________________________________ What are some limitations of this concept? __________________________________ _____________________________________________________________________ 66. There are two ways that speciation occurs geographically. Describe each. _________ _____________________________________________________________________ _____________________________________________________________________ 67. What is adaptive radiation? ______________________________________________ _____________________________________________________________________ 68. “Macroevolutionary changes accumulate through time.” What does that mean? How did complex organs (i.e. eyes) evolve? _____________________________________ _____________________________________________________________________ ____________________________________________________________________ What part of Darwin’s theory does this statement relate to? _____________________ 69. T or F: Over time, trends in evolution can result from adaptations to a changing environment…meaning that evolution is always making more complex beings.