INSTITUTE OF MOLECULAR MEDICINE Programme 10 th Annual Meeting OF The Institute OF Molecular Medicine Trinity Centre for Health Sciences at St. James’s Hospital 9 t h & 10 t h November 2007 Sponsored by: AGB Scientific Limited Alpha Technologies Amgen Biosciences Cruinn Diagnostics Limited Fannin Scientific Limited Fisher Scientific Limited Mason Technology Millipore Randox Laboratories Sarstedt Limited Shire Pharmaceuticals Sigma-Aldrich Limited Unitech INSTITUTE OF MOLECULAR MEDICINE Programme DAY 1 Friday 9th November 8.30 am Registration SESSION I Chairs: Prof Michael Gill, Head of Department of Psychiatry, Institute of Molecular Medicine, TCD and SJH & Dr David Lloyd, Dean of Research, TCD 9.00 am Opening of Meeting & 5th Institute of Molecular Medicine Lecture Prof Dermot Kelleher, Director of Institute of Molecular Medicine, Head of Department of Clinical Medicine, Head of School of Medicine, TCD and SJH “Developing Translational Medicine at an University Teaching Hospital” 9.45 am Prof Frank Gannon Director General, Science Foundation Ireland “Research with Consequences” 10.30 am Coffee Break SESSION II Chairs: Prof Orla Sheils, Department of Histopathology, Institute of Molecular Medicine, TCD & Dr Seamus Donnelly, Director of Academic Medicine & Consultant Physician, Conway Institute, UCD & St Vincent’s University Hospital 11.00 am Prof Bruce Torbett Head of Molecular and Cellular Therapy, Scripps Cancer Centre & Departments of Experimental and Molecular Medicine and Immunology, Scripps Research Institute California, USA “Blocking HIV-1 Entry: Can the Door be Closed Using Gene Delivery?” 11.45 pm Prof Martyn Goulding Molecular Neurobiology, Salk Institute for Biological Studies, California, USA “From Genes to Behaviour: Dissecting the Neural Circuits that Control Walking” 12.30 pm LUNCH INSTITUTE OF MOLECULAR MEDICINE Programme SESSION III Chairs: Prof Alan Irvine, Consultant Dermatologist, Our Lady’s Hospital for Sick Children/SJH and Institute of Molecular Medicine, TCD & Prof Hilary Humphreys, Head of Microbiology, RCSI and Beaumont Hospital 13.45 pm Prof Ajit Lalvani Chair in Infectious Diseases, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, UK “Diagnosing Tuberculosis Infection in the 21st century: New Tools to Tackle an Old Enemy” 14.30 pm Prof Siamon Gordon Prof of Cellular Pathology, Sir William Dunn School of Pathology, University of Oxford, UK “Macrophages – The Two Edged Sword” 15.15 pm Prof Hazel Dockrell Prof of Immunology and Head, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK “Towards Clinical Trials of New TB Vaccines: The BCG Story” 16.00 pm Coffee Break 16.30 pm Prof Colm O’Morain Chair of Medicine, Clinical Medicine & Dean of Faculty of Health Sciences, TCD “Can GI Cancer be Prevented?” SESSION IV Chair: Prof Dermot Kelleher, Director of Institute of Molecular Medicine, Head of Department of Clinical Medicine, Head of School of Medicine, TCD and SJH Introduction: Prof Shaun McCann, Prof of Academic Medicine and Head of Haematology, Institute of Molecular Medicine TCD and SJH 17.15 pm State of the Art Lecture Prof Lucio Luzzatto Scientific Director, Institute Toscano Tumori, Florence, Italy “From Bedside to Bench” 18.00 pm POSTER COMPETITION AWARDS Judges: Prof Martyn Goulding, Prof Hazel Dockrell & Dr David Lloyd 18.15 pm RECEPTION INSTITUTE OF MOLECULAR MEDICINE Programme DAY 2 Saturday 10th November 8.30 am Registration SESSION V Chairs: Prof Mark Lawler, Prof of Molecular Medicine, Institute of Molecular Medicine, School of Medicine, TCD and SJH & Prof Cliona O’Farrelly, Chair in Comparative Immunology, Department of Biochemistry, TCD 9.00 am Dr James O’Donnell Senior Lecturer, Institute of Molecular Medicine, TCD and Consultant Haematologist, SJH “Cross-talk Between Cancer Cell Biology and Coagulation Activation – Clinical Relevance and Novel Therapeutic Strategies” 9.45 am Prof Frank Barry Professor of Cellular Therapy, Scientific Director, Regenerative Medicine Institute, National University of Ireland, Galway “Stem Cells in Tissue Repair” 10.30 am Dr Joe Keane Director of Research, School of Medicine, Institute of Molecular Medicine, TCD and SJH “One New Lung Cancer Patient Everyday: Making a Better Test” 11.15 am Coffee Break SESSION VI Chairs: Prof Shaun McCann, Prof of Academic Medicine and Head of Haematology, Institute of Molecular Medicine TCD and SJH & Prof Thomas Cotter, Prof of Biochemistry, University College Cork 11.45 am Dr Paul Browne Chairman, St James’s Hospital Medical Board and Consultant Haematologist, SJH “Paroxysmal Nocturnal Haemoglobinuria: New Ideas about an Old Disease” 12.30 pm 8th Annual Durkan Lecture Prof Willem Fibbe President, European Hematology Association, Department of Immunohematology & Bloodtransfusion, Leiden University Medical Centre, Netherlands “MSC in the Treatment & Prevention of Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation” 1.15 pm End of Meeting