Cairo University Faculty of Pharmacy Photo Curriculum Vitae First Name Ezz El Deen Title E-mail Phone Title Professor Middle Family Saeed Denshary Department Pharmacology and Toxicology extension Switch 02-23632245 / 02-23639307 02-2567457 / 02-23624917 Education Most Recent Degree Title of Thesis Specialization University Attended Year Ph.D. Study on the hepatoprotective effect of certain drugs against the hepatotoxicity induced by 8-amino and8-hydroxy quinolones in experimental animals Pharmacology Faculty of Pharmacy, Cairo University 1967 Experience A. Teaching Experience Course Title Undergraduate Courses -Pharmacologt &toxicoliogy -Drug information -Bioassay -Terminology -Clinical Pharmacology &Clinical toxicology -laboratory data base Course Code University Cairo University Banisuief, Mansoura ,Tanta, October, Jordan,Kin g Saoud,Khar tom,Ain Shams Academic years Cairo University Faculty of Pharmacy Postgraduate Courses Biochemistry(diplo ma) -Pharmacometrics -Clinical Pharmacology &Clinical toxicology Cairo University, Tanta,Ain Shams, King Saoud Title Demonstrator of Pharmacology Assistant Lecturer of Pharmacology Lecturer of Pharmacology Assistant Professor of Pharmacology Professor of Pharmacology Location Years Pharmacolo gy & Toxicology Department Faculty of Pharmacy Cairo University 1961-1964 1964-1967 1967-1972 1973-1978 1978-1998 Title 1- effect on glucose homeostasis, lipid profile, and adipocyte hormones and their modulation by rosiglitazone and glimepiride. Name of Journal/Conference J. Diabetes Complications. 2- Effect of melatonin and nifedepine on some brain neurotransmitters of global ischemic rats. Fac. Pharm. Cairo University 3- Protective effects of curcumin against ischemia/ reperfusion insult in rat forebrain. Pharmacological Research, Year Volume /Page Cairo University Faculty of Pharmacy 4- Effect of melatonin and nifedipine on some antioxidant enzymes and different energy fuels in the blood and brain of global ischemic rats. J. Pineal Res., 5- Probucol and liver efficiency during chemically-induced heptocorcinogensis Anticancer Research, 6- Probucol and liver efficiency during hepatocarcinogenesis. Anticancer Research, Abstracts of the International Conference, 7- Evaluation of cisplatin combined with ondonsetron on Erlich ascites carcinoma in-vitro and in-vivo. Tumori., 24th International 8- Anti-inflammatory and Conference of antioxidant effects of Nigella Science & sativa oil in sensitized Technology, animals. 2000, New Delhi, India 9- Possible neuroprotective effects of melatonin against ischemia/ reperfusion insult in rat brain. Medical Science Research 10-Radio-protective effect of thiola on radiation-induced functional and structural changes in rat intestine. Egypt. J. Rad. Sci. Applic., 11-Prophylactic role of thiola Cairo University Faculty of Pharmacy against alteration in certain pharmacological responses and cholinesterase activity in isolated jejunum segments of gamma irradiated rats. 12- Effect of Nigella sativa oil on the responsiveness of normal and ovalbuminsensitized guinea pig tracheal chin. 13- Effect of calcium channel blockers verapamil and israpidine on tolbutamide – and glucose (16.7 mM)induced insulin release from the isolated perfused rat pancreas. 14-Counteraction of nifedipine-induced hyperglycemia by metformin. 15-Interaction between diazepam and oral antidiabetic agents on serum glucose, insulin and chromium levels in rats. 16-. Radiation – induced disorders in ovarian function. 17-The hypoglycemic effect of J. Egypt. Soc. Toxicol., XXV Conference of Pharmaceutical Sciences, 1996, Cairo. J. Pharm. Sci., Diabete & Metabolism Bioscience Report Egypt. J.Sci. Applic. Cairo University Faculty of Pharmacy Saudin. Crude Drug research, 18-Effect of bromocriptine on rat pancreatic prostacylin and thromboxane metabolites. FASEB meeting, Las Vegas, N.Y 19-Role of cyclic AMP in dopaminergic D2 receptors of endocrine glands in rats. Bioscience Reports, 20-In vitro and in vivo studies on the effect of bromocriptine Xth International on cyclic nucleotide contents of Congress of endocrine glands. Pharmacology, Sydney, Australia, AguP 986 21-Interaction of glibenclamide, metformin or their combination with certain endogenous or exogenous substances on serum glucose, insulin and chromium levels in rats.1-Dopamine and Bromocriptine. Al-Azhar J.Pharm. Sci., 22-Interaction of glibenclamide, metformin or their combination with certain endogenous or exogenous substances on serum glucose, insulin and chromium levels in rats. Azhar J. Pharm 23-Effect of bromocriptine on lipid plasma levels in rats. 24-Implication of dopaminergic D-2 receptors in carbohydrate, and lipid Life Science, Cairo University Faculty of Pharmacy metabolism in rats. 25-Effect of certain nucleosides and nucleotides on isolated rabbit intestine. 26-Chemical radiation protection of certain aspects of carbohydrate metabolism in irradiated rats. 27-Mechanism of bromocriptine-induced hyperglycaemia. Acta. Pharmacol. Toxicol. J. Bio. Med. Sci. Ther. Egyptian J. Rad. Sci. App Life Sciences, 28-Effect of bromocriptine on blood sugar level in mice. IRCS. Med. Sci. 29-Effect of alpha adrenoceptor agonist and antagonists on insulin secretion, calcium uptake and rubidium efflux in mouse pancreatic islets. Acta Physiol. Scand., 30-Hematologic effects of selenium administration in combination with morphine, cocaine or nicotine in rabbits. 31-Bromocriptine and insulin secretion. 32-Interaction between propranolol and oral antidiabetic drugs on certain carbohydrate metabolic aspects in rats. 33-Interaction between LDOPA and oral antidiabetic Fed. Proc., Bioscience Reports, Egypt, J. Pharm. Sci., Cairo University Faculty of Pharmacy drugs on certain carbohydrate metabolic aspects in rats. 34-Effect of Ovral given concomitantly with chlorpromazine or diazepam on certain functional aspects of rat adrenal cortex. 35-Studies on the combined effect of tobutamide with tetracycline or doxcycline on certain carbohydrate metabolic aspects in rabbits. 36-The Effect of tetracycline on histamine and its metabolizing enzymes. Egypt J. Pharm. Sci. Egypt J. Pharma. Sci., Fac. Pharmacy, (1977) J. Egypt Med. Assoc., 37-A study of the unusual mortality caused by lincomycin in guinea pigs. Bull. Fac. Pharmacy 38-Effect of tetracycline and diazepam on insulin secretion and adenylyl cyclase activity of isolated rat islets of Langerhans. Diabetes and Metabolism, 39-Adenosine and the regulation of insulin secretion by isolated rat islets of Langerhans. Biochemical Journal 40-Effect of chloropromazine on isolated rat islets of Langerhans. 41-Effect of phenformin on the Hormone and Metabolic Research Cairo University Faculty of Pharmacy urinary excretion of female sex hormones in normal and alloxanized rats. 42-Effects of drugs on glucose and tolbutamide-stimulated insulin release from isolated rat islets of Langerhans. 43-Effects of oestradiol, medroxyprogestrone and human placental lactogen on insulin secretion and adenylyl cyclase activity of isolated rat islets of Langerhans. 44-Effect of chronic administration of minor tranquilizers on female sex hormone excretion. 45-Effect of chronic administration of fluphenazine and chlorpromazine on female sex hormone excretion in albino rats. 46-Effect of tolbutamide on the urinary excretion of female sex hormones in normal and alloxanized rats. 47-Effect of the oral contraceptive, Lyndiol, on certain metabolic aspects of adrenocortical hormones in rats. J. Egypt Med. Assoc. Biochemical Pharmacology, Egypt J. Pharm. Saci. J. Egypt Med. Assoc., J. Egypt Med. Assoc., Egypt J. Pharm. Sci J.Drug Res., Cairo University Faculty of Pharmacy 48-Effect of tolbutamide on adrenal catecholamines and ascorbic acid in rats J. Egypt Med. Assoc., 49-Preliminary phytochemical and pharmacological investigations of the roots of different varieties of Cichorium Intybus Planta Medica. 50-Effect of biguanide hypoglycemic agents on the biosynthesis and release of adrenal hormones in rats. J. Egypt Med. Assoc., 51-Influence of the concomitant administration of tolbutamide and chlorpromazine on certain adrenal function in rats. 52-Influence of antazoline and dexamethasone on the toxicity of lincomycin in rabbits. 53- In vitro and in vivo studies on the effect of tolbutamide and phenoformin on adrenal steroidogenesis in the rat. Egypt J. Pharm. Sci., Egypt J. Pharm. Sci. Pharmacological Research Communications 54-Biochemical studies on the hepato-toxicity of novobiocin sodium in rabbits. J. Egypt Med. Assoc., 55-Studies on the protective effectiveness of drugs against the hepatic toxicity of certain amaebicidal agents in rabbits. J. Egypt Med. Assoc., 56-Biochemical studies on the Cairo University Faculty of Pharmacy hepatotoxicity of kanamycin sulphate and lincomycin in rabbits. 57-Studies on the protective effectiveness of choline and methionine against the acute toxicity of primaquine diphosphate in mice. 58-Studies on the protective effectiveness of drugs against the hepatic toxicity of primaquine diphosphate in rabbits. J. Egypt Med. Assoc., A.R. J. Pharm. Sci.ll. Egypt. Med. Assoc., 59-The pharmacological action of substituted amino esters and Bull. Fac. Pharm the corresponding quaternary ammonium salts of the triterpenic acids belonging to the alpha and beta-amyrin groups. triterpenic acids belonging to the alpha and beta-amyrin groups. MEMBERSHIP Pharmaceutical Egyptian Association Egyptian Association of Physiology Egyptian Association of pharmacology Hospital Pharmacy Association Saudia Arab Association of Pharmacy British Association for Diabetic patients Fedral Union for Pharmacy 1- Egyptian Syndicate Cairo University Faculty of Pharmacy Attended Workshops Name Year 1- Funded Projects Title Year Source Amount Signature