UNIT 3 TEST - HISTORICAL EXPERIMENTAL EVENTS Name: ____________________________________ Date: _______________________ Directions: Match the individual or organization with the correct event. ___ 1. Human Genome Project ___ 2. Ian Wilmut ___ 3. Kary Mullis ___ 4. Genentech Co. ___ 5. Cohen & Boyer ___ 6. Paul Berg ___ 7. Arther Kornberg ___ 8. Watson & Crick ___ 9. Ernst Ruska ___ 10. Alexander Fleming ___ 11. Thomas Morgan ___ 12. Robert Kock ___ 13. Johan Miescher ___ 14. Gregor Mendel ___ 15. Louis Pasteur A. Discovered 1st antibiotic – penicillin B. Completed 1st draft of DNA mapping C. Isolated DNA from nuclei of white blood cell D. Formulated basic laws of heredity via plant experiments E. Developed PCR (DNA sequencing and DNA fingerprinting) F. Cloned sheep (Dolly) from adult DNA G. Used restriction enzymes to cut & paste sections of DNA H. Collaborative research on DNA structure model I. Proved microorganisms cause disease – 1893 J. Proved yeast is a living organism K. Genetically engineered insulin “Humulin” L. Discovered DNA polymerase and method of DNA replication M. 1st successful recombinant DNA experiment – bacterial genes N. Built 1st electron microscope – 1932 O. Nobel Peace Prize for research in gene theory (X & Y) Directions: Indicate whether the statement below is true or false by placing a “T” at the blank to the left if the statement is true and an “F” if it is false. Make the false statements true by crossing out the incorrect word and inserting the word to make the statement true at the end of the sentence. __ 1. “Genetic Engineering” evolved with the first patent for gene cloning. __ 2. “Biotechnology” phrased was coined after discovering genes found on chromosomes __ 3. The 1st genetically engineered tomato was produced by Genetech Co. __ 4. FDA declared genetically engineered foods did not require special regulation. __ 5. 21st century biotechnology techniques are centered in biology, chemistry, and physics. ___ 6. Ruska discovered the first cancer-causing virus in 1911. ____ 7. Alexander Fleming discovered penicillin in the 1960s. ____ 8. The Genome Project mapped the human genetic code. ____ 9. Ian Wilmut cloned the sheep, Dolly, from an adult sheep in the 1990s. ____ 10. Genetically engineered insulin, Humulin, was engineered in the 1950s. CTAE Resource Network CTAE Applications of Biotechnology, ABT 3 Written by: Deborah Grimes, June 2010 Page 1 of 1