NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 Members in Attendance: J. Billo, M. Chen, M. Chorghade, C. Costello, M. Filosa, T. Frigo, M. Hearn, M. Hoffman, D. Lewis, M. Schwartz, P. Mabrouk, D. Phillips, J. Piper, D. Rickter, R. Scannell, L. Shao, M. Singer, M. Strem, R. Tanner, and V. Walworth. The meeting was called to order at 4:35 PM with M. Chorghade in the Chair. The May 2007 meeting minutes were approved with minor typographical corrections. Chair: M. Chorghade (written and oral) Jin Ji has resigned as chair of the Speakers Bureau. She is willing to remain in the committee. The inaugural “Advances in Chemical Sciences Symposium” conference held at the Royal Sonesta Hotel, Cambridge, MA on March 30, 2007 was a spectacular success. Under the auspices of these conferences, eminent scientists from the strategic triad of government and industry and academia delivered plenary lectures. The conference brought together 200+ scientists, 19 vendors and 9 corporate sponsors for a scholarly event focusing on medicinal chemistry, organic synthesis and methodology. This year’s plenary lecturers included Robert Grubbs (Caltech), Eric Jacobsen (Harvard), Steven Ley (Cambridge), Tomi Sawyer (Pfizer Research Technology Center), William Greenlee (Schering Plough), and Mark Murcko (Vertex) as plenary lecturers. The topical focus areas covered – medicinal chemistry, pharmaceutical and organic synthesis were areas where the chemical enterprise in our area has a well deserved reputation for excellence. The response from pharmaceutical companies in the area was extremely enthusiastic. A sell out symposium crowd was treated to some exhilarating science from some of the finest practitioners of the discipline. A vendor show was well attended and appreciated. The symposium was co- sponsored by the US (East Coast) Section of the RSC, and IUPAC. Represented on the organizing committee were scientists from many of the Pharma companies in our area. We have thus built a nucleus for the future. Planning for ACS collaboration with the Indian Chemical Society and the hosting of ACS Prospectives conferences in India are in full swing The symposium honoring Ted and Arlene Light has now been organized for the Tuesday of the Boston meeting. The confirmed speakers are 1) Elaine Diggs-ACS HQ 2) John Sophos -ACS HQ 3) Dan Eustace -NESACS. 4) Jim Burke -former ACS Board Chair. I will inaugurate the symposium with a few words and pass the floor to Elaine and John to trace the history of career services and Ted and Arlene's involvement in it. Dan Eustace, Jim Burke and I will speak. Ray O’Donnell has suggested that his words of tribute to Ted and Arlene come during the award function 1 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 We were unfortunately not successful in securing a commitment of the ACSIAC to combine the ACS reception with our German Exchange reception. I attended the ACS meeting in Chicago and had the singular pleasure of presenting the Norris award to a most distinguished recipient-Professor Ben Feringa Expressed condolences to Mary Burgess on the passing of her brother. Flowers have been sent on behalf of the section. Chair-Elect: M. Schwartz No Report Secretary: M. Singer No Report Treasurer: J. Piper March 2007 treasurer’s report was presented and approved as presented by voice vote. Expressed concern about coordinating fundraising efforts by different groups within the section. Archivist: M. Simon No report. Trustees: M. Strem See statement at appended to the minutes. Councilors Reports M. Chen According to sources at the Constitution and Bylaw Committee, there will be eleven pages of petitions ready for voting at the Boston Council Meeting in August. I serve on the Admissions Committee. A white-paper was presented from the Membership Affairs Committee to the Admissions Committee,. ACS is broadening the society’s membership requirements with the following purpose: o To include more scientists and engineers working on the boundaries of chemical science or engineering and using chemical techniques in their everyday work, even though they may not have held a degree in a chemical science or engineering o To make the society more welcoming to multi-disciplinary scientists and international scientists who are not qualified for member status. They could become Society Affiliates. Since the communication system has dramatically improved, our society no longer has boundaries. 2 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 To change Student Affiliate to Student Membership, This will later automatically become Regular Member. The category of Associate Membership will be eliminated. o I attended the following meetings and receptions: Open meeting on “Budget and Finance,” District I Councilor Caucus, Town Hall Meeting, Symposium on “Women Achieving Success,” the Chinese American Chemical Society Banquet, the International Activities Reception and the ACS National Award Dinner. D. Rickter Attended the CCAS executive meeting as an Associate on Friday evening. The CAS staff presented reports of its outstanding successes and current issues of pricing. The open meeting on Monday was notable for the absence of critical questions. Chemical Abstracts is celebrating its 100th anniversary in 2007.The 11 June issue of C & E News will feature this celebration. Attended the third-ever meeting of the ACS Ethics Committee as an Associate on Sunday; Marge Cavanaugh of NSF is the Chair, and Eric Slater, Esq., is the staff person. To the original two subcommittees that deal with the action items (Education and Awareness) has been added an Industrial Subcommittee -- that I have joined. Dr. David Chesney of Houghton, MI, led our first meeting on ethical aspects of the chemical industry. An excellent workshop (with PROF) presented scenarios of workplace ethical issues on Tuesday afternoon. There will be at least four different workshops dealing with ethics for chemists at the Boston meeting. President Katie Hunt arranged Presidential Events on sustainable energy. See http://www.acspresident.org/biosustainability.php#7 and other sites. Prof. Nathan Lewis of CalTech gave a powerful summary of the predicament that the world faces. How do we cut carbon dioxide emissions enough to end the rapid global climate change? Economics, politics, engineering, and science are all parts of the problem. Solar energy is promising but still too expensive. Attended the Silver Circle Breakfast on Tuesday with an outstanding interactive address by ACS Past President Dr. Elsa Reichmanis. Attendance was very good. Had lunch with CINF on Tuesday. The speaker, Ted Smith of the US EPA, gave a comprehensive outline of environmental problems of the Great Lakes Basin. The persistent bio-accumulative toxic substances (PBT’s) are monitored. Attended District I Caucus on Tuesday, catching up on ACS business. 3 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 Acted as a Councilor in the Council Meeting on Wed. By written ballot the Council selected Thomas H. Lane and Howard M. Peters as candidates for 2008 President-Elect. Total attendance at the Chicago meeting was 14 520. Listened to papers in CINF Division and attended CINF events Did the usual Expo, SciTech, social events, and so on. It was a great meeting. Chemical Education: R. Tanner (written and oral) Newell Grants The Northeastern Section of the American Chemical Society is again offering four Lyman C. Newell Grants for the New England Association of Chemistry Teachers’ Annual Summer Conference. This summer the theme of the conference is The Wonders of Glass. It will be held at St. Joseph’s College in West Hartford, CT on August 6-9, 2007. The program can be accessed at http://neact.org/summer_conference.html. The total fees for Monday evening through Thursday morning, including registration, room and board, banquets and socials are expected to be from about $300 to $325. Each Newell Grant will be for $225, paid to the NEACT Summer Conference Registrar/Treasurer. While preference will be given to teachers who are new to teaching or returning to teaching, the awards are open to all secondary school chemistry teachers. Applicants need not be members of the Northeastern Section of the American Chemical Society or of NEACT. The application for the Newell Grants is available on the website of the Northeastern Section at <http://www.nesacs.org>. Applications for the grants are due by May 18, 2007, and all applicants will be notified of the results by e-mail on May 25, 2007 Norris-Richards Undergraduate Summer Research Scholarships The applications for the scholarships were due on April 6 th. The Scholarship Committee received 24 applications by the due date from various colleges and universities within NESACS. All applicants will be notified of the Scholarship Committee’s decisions on April 25, 2007. Registration Grants for High School Chemistry Teachers At the request of the NESACS Planning Committee for the Boston ACS meeting, the Education Committee is coordinating the registration grants for high school chemistry teachers for the national meeting of the ACS that will be held in Boston, MA August 19-23, 2007. The grants are for registration reimbursement for the national meeting for High School Chemistry Teachers within the Northeastern Section of the ACS (i.e. New Hampshire and eastern Massachusetts). The reimbursement will only be for the $78.00 registration fee; transportation, lodging, and food will not be reimbursed. Registration for the meeting will entitle them to access to all workshops, any session in any division, all presentations, exhibitions, and non-ticketed events throughout the meeting. The total amount available for the grants are $1000 or 12-13 grants total. 4 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 The Chemical Education Division (CHED) is presenting a special education program for high school chemistry teachers on the opening Sunday of the meeting, August 19th. Registration at the meeting entitles them to the High School Day Luncheon and Door Prize Raffle. Applications can be accessed though the NESACS website at http: www.NESACS.org. The deadline for applications is June 15, 2007. All applicants will be notified by e-mail on June 22, 2007. Grants-in-Aid The Education Committee has been awarding Grants-in-Aid of $250 each to four undergraduates at colleges and universities within the Northeastern Section to enable them to attend the spring ACS National Meeting to present a paper at the Undergraduate Research Poster Session in the Division of Chemical Education. Matching funds have been committed by the institutions to support the students’ travel. The recipients are also required to participate in the Northeast Student Chemistry Research Conference (NSCRC) in April. The costs for this activity have been increasing. Assuming a minimum of three nights (Saturday, Sunday and Monday) and assuming a shared room would be at least $300, airfare to most cities for the Spring meeting to be at least $300, registration for student ACS members to be $78 ($160 for nonstudent affiliate members), plus costs for food and other transportation, the expenses amount to least $800. Given these current expenses, it is proposed that the Grants-in-Aid be increased to $350 with a required increase of matching funds to $350. Motion: To increase the award for Grants-in-Aid from $250 each to $350 each for 2008. Second by M. Hoffman. Discussion: The total expense is $400 from the education budget. The expense needs to be approved now, in order to get proper advertising in the fall 2007. Motion passes by voice vote. Board of Publications: V. Walworth The website continues to be an issue under review. D. Cunningham is actively working with Satish to improve the website. All comments and concerns about the website should be sent to the Board of Publications for their review and action as appropriate. Much discussion on the need for a well maintained website was raised. Consider listing David Cunningham as the main website contact person Can the Board of Publications develop an action plan for the website that includes looking at hiring a Webmaster with the associated costs. Are their section funds available from the Trust to fund a webmaster What are the future roles of the Webmaster and the paid consultant? Nucleus: M. Filosa May issue is at the printers. 5 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 Summer issue deadline is June 15th. Need additional written content for the issue. Medicinal Chemistry Group: L. Shao Medicinal chemistry group will have the first symposium for the year 2007 on May 17th at 3pm at Emanuel College, Boston MA. The topic of the symposium is “Lead Optimization Strategies” We have four speakers presenting on that day. The speakers are: Prof. L.V. G Nargund ,from Nargund Research Foundation, Nargund College of Pharmacy, Bangalore, India, Dr. Neal Green, from Wyeth Research, Cambridge, MA, Dr. Horst Hemmerle from Eli Lilly Dr. Mark Goulet from Merck Research Laboratories, Boston, MA. . All the necessary information about this meeting has been sent out Nucleus. National Meeting: M. Hoffman A reception is being planned for Sunday afternoon sponsored by NESACS and the Division of Chemical Education and the German Chemical Society. Funds are being solicited from German chemical companies. Motion by M. Strem: To award Kurt Begitt of the GDS be presented by NESACS with an ACS Salute to Excellence Award to be presented at the Sunday reception at the ACS meeting in Boston. Second by M. Hearn. Discussion: Kurt Begitt has been one of the key leaders over the past years representing the GDS for the GDS – YCC student exchange program. Motion passes by voice vote. NERM: M. Hoffman (written and oral) An interim meeting of the Board of Directors of the Northeast Region of the American Chemical Society, Inc. (NERACS) was held on March 27, 2007, in Chicago, IL. Present were Julie Smist (Chair), Dick Cobb (Vice-chair), Chris Masi (Secretary), Wayne Jones (Treasurer), Linda Farber (Representative from the Western Connecticut Local Section), and Morton Hoffman. A check for $12,000 was presented to NERACS from the excess of income over expenditures for NERM 2005. It is anticipated that NERM 2006 will provide the NERACS treasury with approximately $30,000 after all the accounting of that meeting has been completed. There will be no NERM in 2007 because the ACS national meeting will be held in Boston. NERM 2008 will be held in Burlington, VT, June 29-July 2, 2008. The Green Mountain Local Section will host the meeting. Plans are evolving for NERMs in 2009 in western Massachusetts, 2010 in the Potsdam, NY, area, and 2012 in Rochester, NY. 6 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 A discussion was held about holding a joint Northeast-Middle Atlantic regional meeting (NERM-MARM) in 2011. [The national meetings will be held in Anaheim (Spring) and Chicago (Fall) in 2011.] Such a meeting could be held in a location at or near the boundary of the regions, e.g., White Plains, NY, so as to be easily accessible by car, train, and air to participants from both regions. Wayne Jones will be present at MARM 2007 and has been invited to the meeting of the Middle Atlantic Region to discuss this option. Morton Hoffman will also be at MARM to represent the CHED High School Teacher Award, and will be available for discussions. Local sections within the Northeast and Middle Atlantic Regions that are willing to co-host the meeting will have to be identified. The next meeting of the NERACS Board of Directors will take place in Boston in August. Sense of the Board Motion: NESACS will co-host the 2011 joint NERMMARM meeting. Motion passes on voice vote. M. Hoffman to communicate this to both NERM and MARM organizers. NCW C. Jaworek-Lopes (written report) Nine haikus from three schools (Lebanon High School, two elementary schools in Bedford, and Norwood High School) were received as part of Chemists Celebrate Earth Day. Two haikus were sent on to Washington, DC for judging. All participants and their teachers will receive small gifts. The haikus submitted are: Written by Dan Sudman, Grade 10, Norwood High School Contamination, Destroying our health and earth. The end approaching. Pollution written by Gina Han, Grade 4, Lt. Job Lane Elementary School Gases, oils, fuels It all causes pollution. We need to stop now. Norris Award Committee: J.D. Smith (written report) The deadline for receipt of new or revised nominations is April 15. There are 8 previous nominations but no new ones yet. The Committee will hold a teleconference in mid-May to select the Awardee. Reservations have been made at the Harvard Faculty Club for Thursday, November 8th, assuming that the Awardee selected will be able to make that date. 7 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 Summerthing: M. Singer Tickets are available through the section office for the Lowell Spinners game on Saturday July 14th. Meeting was adjourned at 5:50 PM. Respectfully Submitted Michael Singer NESACS Secretary 8 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 REPORT TO NEASCS BOARD ON THE GERMAN EXCHANGE AT THE ACS NATIONAL MEETING IN BOSTON Morton Z. Hoffman, Boston University Submission of abstracts: All fourteen of the German graduate students have submitted abstracts to the relevant technical divisions for presentation in the poster sessions and Sci-Mix. 1. Dominik Margraf Johann Wolfgang Goethe-Universität, Frankfurt Title of abstract: Pulsed Electron-Electron Double Resonance: Beyond measuring distances Technical division for presentation: PHYS 2. Cathrin Corten Technische Universität Dresden Title of abstract: Multi-sensitive hydrogel thin films: From synthesis to application Technical division for presentation: PMSE/POLY 3. Eva-Maria Jahn Ludwig-Maximilians University, Munich Title of abstract: Synthesis of natural tRNA modifications Technical division for presentation: ORGN 4. Helke Döring Chemnitz University of Technology Title of abstract: Kinetic measurements using catalyst coatings Technical division for presentation: ICE 5. Naho Fujimoto Research Center Borstel Title of abstract: Glycosylceramides: Synthesis and biophysical properties Technical division for presentation: ORGN 6. Dominik Albrecht Technische Universität München Title of abstract: Enantioselective intramolecular [2+2]-photocycloaddition reactions of tetramic acid esters and their structural homologues mediated by a chiral lactam host Technical division for presentation: ORGN 7. Tom Grossmann Humboldt University, Berlin Title of abstract: DNA-catalyzed organic transfer reaction for sequence-specific DNAdetection Technical division for presentation: ORGN 8. Philipp Wacker University of Potsdam Title of abstract: Conformational analysis and ring current effects of porphyrins studied by molecular modeling 9 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 Technical division for presentation: ORGN 9. Jens Breffke Humboldt-University of Berlin Title of abstract: No dual fluorescence in trans-4-dimethylamino-4’-cyanostilbene (DCS) Technical division for presentation: PHYS 10. Jörg-Joachim Nitz Max-Planck-Institute for Coal Research, Mülheim an der Ruhr Title of abstract: Surface modified ordered mesoporous carbons Technical division for presentation: COLL 11. Igor Schapiro University of Duisburg-Essen Title of abstract: Ab initio molecular dynamics of visual pigment chromophore models Technical division for presentation: COMP 12. Hanns Martin Kaiser Universität Rostock Title of abstract: New synthetic protocols for the preparation of unsymmetrical bisindoles Technical division for presentation: ORGN 13. Peter Wich Universität Würzburg Title of abstract: Stereoselective binding of peptides by artificial receptors in water: New insights into the molecular recognition of biologically relevant substrates Technical division for presentation: ORGN 14. Franziska Luschtinetz University of Potsdam Title of abstract: New perspectives on fluorescence probes for protein single molecule spectroscopy Technical division for presentation: PHYS Symposium: The NESACS co-sponsored symposium, Connections to Germany: Research and Education Opportunities, in the Division of Chemical Education (CHED) is scheduled for Sunday afternoon, August 19. In addition to NESACS, other co-sponsors will be the German Chemical Society, the ACS International Activities Committee, the CHED International Activities Committee, the Graduate Student Symposium Planning Committee, the Society Committee on Education, and the Women’s Chemist Committee. Requests for co-sponsorship are still outstanding to the ACS President and Younger Chemists Committee. Here are the titles, abstracts, and approximate times of the presentations. 1.30 PM – Welcoming remarks 1:35 PM – Biological chemistry research at Ludwig-Maximilians University, Munich, Germany Eva-Maria Jahn and Thomas Carell, Department of Chemistry, Ludwig-Maximilians University, Butenandtstrasse 5-13 (Haus F), 81377 München, Germany, Fax: ++49 89 2180 77756, EvaMaria.Jahn@cup.uni-muenchen.de 10 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 The center of excellence, “Munich Center for Integrated Protein Science" (CIPSM), which was founded in 2006, connects internationally recognized scientists from the two universities in Munich with those from the neighboring Max Planck Institutes and the GSF in the Munich area. This new interdisciplinary network creates an excellent scientific environment in which the individual research facilities can develop their expertise synergistically. The central idea of CIPSM is to achieve a deeper understanding of biological processes at the molecular and cellular level. This requires interactive research of groups from different disciplines, including chemistry, physics, and biology. The unifying theme is the understanding of proteins in their natural context at all levels of organization of life. Imbedded in this framework, our group is working on the biological functions of modified natural RNA nucleosides. This research encompasses different topics, ranging from synthesis to the investigation of their biological functions, such as their biosynthesis, as well as their interactions with the ribosome or enzymes during translation. 1:55 PM – DNA as catalyst in organic synthesis: An approach for sequence-specific DNA detection Tom N. Grossmann and Oliver Seitz, Department of Chemistry, Humboldt University, Berlin, Brook-Taylor-Str. 2, Berlin D-12489, Germany, tom.grossmann@gmx.de DNA-templated reactions are emerging as a general approach to control the reactivity of synthetic molecules by modulating the effective molarity. DNA templates align the reactive groups of these molecules to allow fast and selective reactions at reactant concentrations that are much lower than those required for conventional synthesis. A central issue in DNA-templated synthesis is the design of reactions using the DNA-template as catalyst. So far, approaches suffer from fast off template reactions or increased affinity of the product to the DNA-template, preventing high catalytic activity. Catalysis would support signal amplification and enable highly sensitive DNAdetection. We have developed a DNA-catalyzed transfer of a reporter group, generating high catalytic turnover numbers in a sequence-specific manner (Grossmann, T. N.; Seitz, O. J. Am. Chem. Soc. 2006, 128, 15596-15597). This DNA-catalyzed transfer is a new concept and is the first reaction to combine high catalytic activity of the DNA-template with useful reaction yields and low background. 2:15 PM – Characterization of smart materials synthesized via controlled radical polymerization Cathrin Corten and Dirk Kuckling, Fachrichtung für Chemie und Lebensmittelchemie, TU Dresden, D-01062 Dresden, Germany, Fax: +49 351 37122, dirk.kuckling@chemie.tu-dresden.de This presentation describes a graduate research project, which is integrated into the Collaborative Research Centre 287, “Reactive Polymers in Inhomogeneous Systems, in Melts, and at Interfaces," which is supported by the German Research Foundation (DFG). Our work aims to integrate multiple functions into polymeric materials. For example, photo cross-linkable multi-sensitive block copolymers based on a pH-sensitive component and a temperaturesensitive component were synthesized via nitroxide-mediated radical polymerization (NMRP). It was shown that these smart block copolymers could be synthesized with variable molecular weight and narrow molecular weight distribution. Using the photo cross-linking technique, the preparation of thin hydrogel layers was successful. The swelling behavior of these responsive films was investigated by different optical methods. The high sensitivity to external stimuli allows the application of such hydrogel layers as sensor material. 2:35 PM – Intermission 2:45 PM – DAAD: Funding academic exchange and promoting research in Germany Christian Schaefer, North America Section, DAAD, Kennedyallee 50, Bonn, Germany, Fax: 0049-228-882-551, schaefer@daad.de 11 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 The Deutscher Akademischer Austausch Dienst (German Academic Exchange Service) or DAAD is an organization of the German universities with the objective of supporting international cooperation in higher education and research. In 2006, DAAD provided funding for about 55,000 people from around the world. In addition to providing scholarships, DAAD supports cooperation between German and foreign universities and research groups. Our leading programs for North America are RISE (Research Internships in Science and Engineering, www.daad.de/rise), Study Scholarships (for undergraduates, graduates and Ph.D. students), and Mobility Funds for the cooperation of researchers in Germany and the United States or Canada. DAAD also supports the development of exchange programs and joint degree or double degree programs. Furthermore, the DAAD promotes the dynamic and highly distinguished German science and research system in the international context. Comprehensive information is available at [www.daad.org, www.daad.de] and [www.research-in-germany.de]. 3:05 PM – Basic research in Germany: DFG, the German Research Foundation Georg Bechtold, Chemistry and Process Engineering, Deutsche Forschungsgemeinschaft e.G, Kennedyallee 40, Bonn 53175, Germany, Fax: 0049-228-8852777, georg.bechtold@dfg.de The Deutsche Forschungsgemeinschaft (German Research Foundation) is the central research funding organization that promotes basic research in Germany. The DFG serves all branches of science and the humanities by funding research projects and facilitating cooperation among researchers. Promoting the advancement of Young Researchers throughout all stages of their research career is a key goal of the DFG. The DFG also encourages international research collaboration. Many of the programs have a specific international focus. These opportunities include funding for individuals, individual projects, and coordinated programs. The DFG promotes stronger international cooperation, greater international mobility of researchers, and further internationalization of universities in Germany. The DFG offers various opportunities to postgraduates, PhD students, and postdocs to spend a certain time of their educational career, and sometimes the rest of their lives, in Germany. In this presentation, a short overview of the many possibilities is given, from doctoral studies to professorships. 3:25 PM – The Boston Consulting Group Germany Claudia Jopp, Recruiting, The Boston Consulting Group Germany, Stadttor 1, Duesseldorf 40625, Germany, Fax: +49 211 3011 3106 The Boston Consulting Group, as a worldwide leader in strategic consulting, stands for the innovative solutions that we carry out in collaboration with our clients. Founded in the U.S. in 1963, BCG today maintains 63 offices in 37 countries throughout the world. Eight offices and 677 consultants are based in Germany, Austria, and Greece. Here alone, BCG generated revenues of 305 million euros in 2006. We provide consulting services in all industries and business sectors. Our consulting approach starts with a deep understanding of our clients' businesses and their specific market and competitive situations. From there, we develop tailored solutions together with clients and support their implementation and establishment at the respective companies. BCG seeks exceptional graduates in all fields, as well as young professionals eager to learn continuously and take on new challenges. We are looking for people with self-initiative, curiosity, and keen perceptive abilities. Abstract, analytical reasoning and confidence in working with numbers are just as important for consulting work as communication skills and a deep desire to make a difference. In short: We seek people who view thought and action as a unified whole. 3:45 PM – Intermission 3:55 PM – The German Chemical Society and chemical education and research in Germany Kurt Begitt and Jens Breffke, Gesellschaft Deutscher Chemiker, Varrentrappstrasse 40 - 42, Frankfurt am Main 60486, Germany, Fax: +49-69-7917-322, K.Begitt@gdch.de, breffke@web.de 12 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 Europe is heading for a major change in its higher education system with the goal of an increased harmonization of the various national systems. The Gesellschaft Deutscher Chemiker (GDCh) is supporting the Bologna process. The GDCh sees an increasing number of foreign chemistry students coming for some part of their education to German universities. The universities are well prepared to welcome international students. For graduates in chemistry, the chemical industry is the main employer offering interesting career opportunities. The German chemical industry is the largest within the European Union. On a global scale, it is the fourth largest chemical industry and employs close to 500,000 people in Germany. For a research position in industry or a research center the candidate is expected to have a Ph.D. degree and hence more than 90% of the current chemistry graduates in Germany leave university with a doctoral degree. The GDCh-Young Chemist Forum (JCF) is the very active section of students and younger chemists within the GDCh. The JCF was founded in 1997 in Berlin. Today, in the year 2007, the JCF has more than 6,000 members and is committed to its mission on local, national, and international levels. 4:20 PM – Younger Chemists Committee of the Northeastern Section Laila Dafik, Department of Chemistry, Tufts University, 62 Talbot Avenue, Medford, MA 02155, Laila.Dafik@tufts.edu The Northeastern Section Younger Chemists Committee (NSYCC) is an important activity of the Northeastern Section (NESACS), which encompasses Eastern Massachusetts and New Hampshire. NSYCC organizes many events for younger chemists in the region, such as the Northeastern Student Chemistry Research Conference (NSCRC), a free career fair, and social gatherings. NSYCC is very proud to be part of the very successful annual German Exchange Program between the GDCh-JCF and NESACS. Since 2001, a group of younger chemists has traveled across the Atlantic Ocean to participate in a week-long program that consists of visits to local university research laboratories, tours to industrial facilities, and presentations at regional research conferences. Foreign career, research, and educational opportunities are emphasized throughout the week. 4:40 PM – Study abroad opportunities in Germany for American science and engineering undergraduates Morton Z. Hoffman, Department of Chemistry, Boston University, 590 Commonwealth Avenue, Boston, MA 02215, Fax: 617-353-6466, hoffman@bu.edu, and Nancy Downey, International Programs, Boston University Science and engineering undergraduates have historically been extremely underrepresented among American students who study abroad. The reasons that students in non-scientific disciplines are attracted to study abroad are well known: curricular flexibility, faculty enthusiasm, administrative support, historical basis. Despite the international connections that many science and engineering faculty have, they do not necessarily see the added value of the study abroad experience to the students' overall education. A real problem to the student is the fact that highly specialized courses and research fill the junior and senior years when most travel abroad has been traditionally done. While it is possible for American undergraduates to enroll directly in a university in another country (Germany, for example), there are a number of serious deterrents: instruction would be in the local language, the academic calendar will probably not coincide with that of the home institution, and the expectations of the instructors might not be compatible with the background and maturity of the students. An appropriate alternative to the total immersion approach is to have the American science and engineering courses replicated at a foreign site. Boston University's Dresden Science and Engineering Programs will be presented as a model that affords students the opportunity to study abroad in their major and avoids the common obstacles. 4:55 PM – Closing remarks 13 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 5:00 PM – End 14 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 15 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 16 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 17 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 The 11th Andrew H. Weinberg Memorial Lecture This annual event highlights the achievements and focuses on the development of new strategies for the treatment of cancer patients Malcolm Smith, MD, PhD Associate Chief, Pediatric Oncology Cancer Therapy Evaluations Program, NCI “Picking Winners- Selecting the Right Molecularly Targeted Agents for the Right Childhood Cancers" Please join us Monday, May 14th, 4:00pm The Smith Family Room (D1620) Dana-Farber Cancer Institute, 35 Binney Street, Boston, MA 02115 Malcolm Smith is a leader in the Pediatric Preclinical Testing Program (PPTP) an NCI initiative designed to address the challenge facing pediatric oncology researchers of reliably prioritizing new agents for study in children with cancer. The PPTP systematically tests 10-15 new agents annually against in vitro and in vivo preclinical models of childhood cancers, with testing ideally occurring near the time that the agents are entering testing in humans and prior to their initial evaluation in children. . The PPTP utilizes a set of molecularly characterized preclinical models (approximately 100 cell lines and xenografts) that recapitulate key molecular and biological characteristics of their clinical counterparts. The Andrew H. Weinberg Fund was created to bring researchers together from the field of chemotherapy development with those in the medical community to foster an environment for synergy and new approaches for cancer research. The fund is endowed through the generous support of family and friends, as well as the Medicinal Chemical Group, the Northeastern section of the American Chemical Society, and the Dana-Farber Cancer Institute. 18 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 For more information, please contact Jill LaCoursiere at 617-632-3971 or jill_lacoursiere@dfci.harvard.edu Picking Winners – Selecting the Right Molecularly Targeted Agents for the Right Childhood Cancers Malcolm A. Smith, MD, PhD From 1975 to 1998 the death rate from childhood cancers declined at an annual rate of 2.7% per year, continuing a consistent decline in childhood cancer mortality that began in the 1960s. However, from 1998 through 2003 childhood cancer mortality remained unchanged. How can childhood cancer researchers get beyond the impasse that has been reached in identifying more effective curative treatments for children with cancer? Progress in developing more successful systemic treatments will require reliable prioritization of effective agents for clinical evaluation against specific childhood cancers. This is a difficult task given the large number of novel anti-cancer agents with distinctive molecular targets that are now available for clinical evaluation. The Pediatric Preclinical Testing Program (PPTP) is one step that the National Cancer Institute is taking to develop data that will be useful for prioritization decisions. The PPTP utilizes a set of molecularly characterized preclinical models (approximately 100 cell lines and xenografts) that recapitulate key molecular and biological characteristics of their clinical counterparts. The systematic evaluation of agents by the PPTP allows the identification of histiotype-specific response patterns, candidate biomarkers of response, and pharmacokinetic estimates of drug exposures associated with antitumor activity. The PPTP is evaluating novel agents that target key biological processes and pathways such as angiogenesis, mTOR signaling, receptor tyrosine kinase signaling, and Bcl-2 family control of apoptosis. Testing results in these areas will be presented and their implications for clinical prioritization decisions will be discussed. The PPTP and related preclinical activities are key components of a strategy for once again identifying more successful treatments for children with cancer through the selection of effective molecularly targeted agents for clinical evaluation against specific childhood cancers. 19 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 COUNCILOR TALKING POINTS SUMMARY OF GOVERNANCE ACTIONS/REPORTS AMERICAN CHEMICAL SOCIETY 233rd ACS NATIONAL MEETING CHICAGO, IL MARCH 25-29, 2007 The following summary is provided to help councilors report to their local sections and divisions on key actions of the ACS Council and Board of Directors at the 2007 spring national meeting. ACTIONS OF THE COUNCIL Election Results The Committee on Nominations and Elections presented to the Council the following nominees for selection as candidates for President-Elect, 2008: Pat N. Confalone, Thomas H. Lane, William A. Nugent, and Howard M. Peters. By written ballot the Council selected Thomas H. Lane and Howard M. Peters as candidates for 2008 President-Elect. These two candidates will stand for election in the Fall National Election. The Committee on Nominations and Elections announced the results of the election to select candidates from the list of nominees to represent District II and District IV on the Board of Directors for the term 2008-2010. Nominees for District II included: Robin J. Hood, Joseph R. Peterson, Diane Grob Schmidt, and Steven W. Yates. Nominees for District IV included Paul F. Barbara, Eric C. Bigham, John P. Fackler, Jr., and Gregory H. Robinson. By mail ballot the councilors from these districts selected Joseph R. Peterson and Diane Grob Schmidt as District II candidates; and as District IV candidates, Eric C. Bigham and Gregory H. Robinson. Ballots will be mailed on or before October 10 to all members in District II and District IV for election of a Director from each District. Candidates for Directors-at-Large The Committee on Nominations and Elections announced the selection of the following candidates for Directors-at-Large for a 2008-2010 term: Janan M. Hayes, Helen A. Lawlor, Kent J. Voorhees, and Frankie K. Wood-Black. The election of two Directors-at-Large will be conducted in the fall. Ballots will be mailed to the Council on or before October 10. Committee Performance Reviews As part of a regular review, the Council VOTED to continue the Committee on Science, the Women Chemists Committee, and the Younger Chemists Committee - subject to concurrence by the Board of Directors. The Committee on Science provides an organizational framework to facilitate policy formulation, actions, and planning in several areas of ACS activity directly related to the science of chemistry. The Women Chemists Committee was established to recognize women chemists and to encourage them to take an active interest in Society activities; and the Younger Chemists Committee facilitates communication of ideas and attitudes between the governing bodies of the Society and younger chemists. Petitions 20 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 (For Action) The Council received three amendments to the ACS Bylaws (Petitions) for action: the Petition on Election Procedures 2006, the Petition on Rules for Nominating Members of N&E for National Offices, and the Petition on Multi-Year Dues. The Council VOTED to split consideration and action on the Petition on Election Procedures 2006 into two parts: Part 1 changes the timing of run-off elections and specifies an election process for situations in which only one Director-at-Large position is open. Part 2 addresses consistency in national election procedures. It proposes changes to standardize the petition and election processes for President-Elect and all Director positions based on percentages of voting members. It replaces language specifying a required absolute number of petition signatures for nomination of candidates for President-Elect, and Director-at-Large with language specifying a higher requirement for petition signatures as a percentage of the membership for nomination of candidates for these offices. The Council VOTED to accept Part 1. For Part 2, the Council VOTED to recommit this petition back to the Committee on Nominations and Elections and ask that they reconsider the signature requirements, procedures for processing electronic signatures, and those suggestions arising from the Governance Review Task Force pertinent to election procedures. The Petition on Rules for Nominating Members of N&E for National Offices establishes a one-year waiting period following service on the Committee on Nominations and Elections before an individual can be nominated for District Director, President-Elect or Director-atLarge. The Council VOTED by recorded vote to defeat this petition. The Council VOTED to accept the Petition on Multi-Year Dues. This petition will allow members paying full dues without any of the discounts to pay for periods of two or three years if they wish, at a rate equal to two or three times the rate for a one year period. Council also VOTED to make this petition effective when technical components are instituted to offer and track the payments, but no later than January 1, 2010. The Board of Directors will vote within 90 days on whether to ratify the approved petitions. (For Consideration) The Council received one petition for consideration: the Petition on Local Section Affiliations. The petition addresses a difference in current Society bylaws regarding the responsibilities of the Committee on Local Section Activities (LSAC) and the Committee on Divisional Activities (DAC) in oversight of the establishment of affiliations by local sections and divisions, respectively. The petition grants responsibilities for LSAC parallel to those currently established for DAC. Action is expected on the petition at the fall national meeting. 2008 Member Dues The Council VOTED to set the member dues for 2008 at the fully escalated rate of $136. This rate is established pursuant to an inflation-adjustment formula in the ACS Constitution and Bylaws. The Society’s Finances 21 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 The Society ended 2006 with a net contribution from operations of $12.2 million, on revenues of $424.0 million and expenses of $411.9 million, which was $7.8 million favorable to the approved budget. The favorable variance was primarily attributable to higher-than-budgeted electronic services revenue and investment income, as well as expense savings from lowerthan-budgeted health care costs and reduced IT spending. In addition, the Society ended 2006 in full compliance with the Board-established financial guidelines. Registration Report As of March 27, 2007, the ACS fall national meeting had attracted 14,520 registrants as follows: Regular attendees 7,152; Students 5,059; Exhibitors 1,283; Exposition only 573; and Guests 453. Future National Meetings The Council VOTED to approve dates and sites for 2017 national meetings as follows: April 2-6, San Francisco, California; and September 10-14, St. Louis, Missouri. New Local Section The Council VOTED to establish the Snake River Local Section with headquarters in Boise, ID. This brings the total number of local sections to 190. Member Statistics ACS closed 2006 with 160,491 members, the highest year-end membership since 2002. Of the 17,857 applications processed in 2006, more than 1,000 came from the Member-Get-AMember campaign, in which many councilors participated. Governance Review The Council received a report on the recent activities of the Governance Review Task Force. Councilors were informed that since the last Council meeting, the task force has met twice and action teams have been actively addressing those areas under the “Advance” category. Councilors also learned that the Council Policy Committee and the Board of Directors VOTED, as recommended by the Governance Review Task Force, to accept four recommendations under the “Refine” category. Chemical Professional’s Code of Conduct The Council VOTED to approve the Chemical Professional’s Code of Conduct as submitted by the Committee on Economic and Professional Affairs. This document offers guidance for Society members in various professional dealings, especially those involving conflicts of interest. Resolutions The Council adopted resolutions in memory of deceased councilors and ACS Past Presidents Robert Parry (1982), and Fred Basolo (1983). ACTIONS OF THE BOARD OF DIRECTORS The Board’s Standing Committees 22 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 The Board of Directors received a report on the screened list of candidates from the Committee on Grants and Awards for the 2008 Priestley Medal and the Volunteer Service Award. The Board will announce the winners of these two awards after its June meeting. The Board also VOTED to approve a new award: the ACS Award for Affordable Green Chemistry, and an endowment to support the award sponsored by the Rohm and Haas Company. The Committee on Grants and Award concluded its report with an update from the PRF Steering Committee. The Board received a report on the activities of the Committee on Public Affairs and Public Relations where they were informed of its actions at this meeting and recent governance advocacy activities since the committee’s last meeting in December. Activities of the Board’s Task Forces and Working Groups The Board of Directors received status reports from several of its task forces and working groups namely: the Governance Review Task Force, the International Strategy Advisory Group, Percy Julian Task Force, the Board Oversight Group on Leadership Development, the working group on 2007 Board Goals and the working group charged with planning the Board’s retreat. The Board VOTED, on the recommendation of the Governance Review Task Force, to accept four recommendations under the “Refine” category. The Board also expressed its appreciation to the Percy Julian Task Force for its outstanding work and presented its members with plaques of the US House of Representative Resolution (February 2007) honoring the life and contributions of Dr. Julian. Recognition of Chemical Society Milestone Anniversaries The Board approved resolutions recognizing the 100th anniversary of the Hungarian Chemical Society and the 150th anniversary of the French Chemical Society. The French Chemical Society’s anniversary will be celebrated in connection with its national meeting and the “C6” meeting, a summit of six large international chemical societies, in July. The Hungarian Chemical Society will celebrate its anniversary in June. The Review and Approval of Two Policies The Board reviewed and approved a statement on scholarship as presented by the Committee on Education, and a series of policies for the acceptance of gifts as supported by the Task Force on Development Activities. Compensation of Society Staff On the recommendation of the Committee on Executive Compensation, the Board VOTED to approve several actions relative to compensation for the Society’s executive staff. The compensation of the Society’s executive staff receives regular review from the Board. The Executive Director/CEO Report The Executive Director/CEO led a discussion on challenges facing the ACS, 2007-2011, including demographic/disciplinary, international, workforce readiness & science competitiveness, knowledge transfer and governance reform, and on priority recommendations for addressing those challenges. She also, along with several of her direct reports, updated the Board on the following issues: the impact of evolving information and communication technologies and trends on the Society, the Web Presence initiative, the ACS Green Chemistry Institute, and the activities of Chemical Abstracts Service, the Publications Division, and the Society’s General Counsel. 23 of 24 NESACS Board of Directors Meeting University of Massachusetts (Boston) Campus Center April 12th , 2007 24 of 24