1 Class 7 Wellness University Diseases of Lifestyle: The Secret Killer Script Slide 1: Title Welcome to Wellness University. [Welcome new people and explain program] Today’s class is called Diseases of Lifestyle: The Secret Killer. What is a disease of lifestyle? Lifestyle diseases are diseases that appear to become ever more widespread as the countries of the world become more industrialized. Lifestyle diseases are different from other diseases because they are preventable, and can be stopped or reversed if changes in diet, lifestyle, and the environment are made soon enough. Slide 2: Diseases of Lifestyle • • • • • • • • • • • • • • • Alzheimer's disease Atherosclerosis Asthma Cancer Chronic liver disease COPD Type 2 diabetes and metabolic syndrome High blood pressure Heart disease Crohn's disease Nephritis or chronic renal failure Osteoporosis Stroke Depression Obesity "In many [Western] countries, peoples' diet changed substantially in the second half of the twentieth century, generally with increases in consumption of meat, dairy products, vegetable oils, fruit juice, and alcoholic beverages, and decreases in consumption of starchy staple foods such as bread, potatoes, rice, and maize flour. 2 Other aspects of lifestyle also changed, notably, large reductions in physical activity and large increases in the prevalence of obesity." "It was noted in the 1970s that people in many Western countries had diets high in animal products, fat, and sugar, and high rates of cancers of the colorectum, breast, prostate, endometrium, and lung; by contrast, individuals in developing countries usually had diets that were based on one or two starchy staple foods, with low intakes of animal products, fat, and sugar, and low rates of these cancers." Key TJ, Allen NE, Spencer EA. The effect of diet on risk of cancer. Lancet. 2002 Sep 14;360(9336):861-8. Slide 3: Lifestyle Diseases are Reversible Lifestyle disease ARE reversible Lifestyle diseases ARE NOT reversible by drugs Lifestyle diseases are only reversible by making specific positive changes in your lifestyle before permanent damage is done to your body. If your heart is permanently damaged due to disease, if cancer has ravaged your body or if a diabetic never does anything but keep pumping themselves full of insulin, then eventually the damage is not reversible. When is the best time to make any lifestyle change? Yesterday. Slide 4: “I Got This from my… There’s nothing I can do about it, I got this from my… • Parents • Grandparents • A bad virus • Bad luck, a bad roll of the dice We hear this all the time… “Too bad… you got your parents and your grandparents genes!” We’ve been brainwashed over the past 50 years that heart disease, cancer, and diabetes are not only NOT our fault, but that we can blame it on our parents and our grandparents! Modern research has been found that changing your lifestyle changes your genes… it is a new science called epigenetics. In a pilot study done by Dr. Dean Ornish, a nutritionist, involving men with prostate cancer it was found that more than 500 genes changed the way they 3 worked when the patients did not take the drugs but instead followed a wholegrain plant-based diet and exercised Genes with beneficial effects, including some tumor-suppression genes, became more active in the male subjects, and genes with deleterious effects, including some cancer-promoting genes, were switched off. How the subjects exercised and what they ate changed the way their genes expressed themselves. Slide 5: The Loaded Gun Analogy Let me put it this way… As one researcher has put it “Faulty genetics loads the gun, lifestyle pulls the trigger.” This idea has some far-reaching implications, if our lifestyle brings these diseases on, is it possible that an improvement in our lifestyle could also prevent or even reverse these conditions? The Pima Indians of Arizona are the poster children for diabesity… obesity and Diabetes type 2. They have the same genetics as the Pima Indians of northern Mexico, however, because of adopting the Standard American Diet which is high in processed foods, refined wheat and sugar and a lifestyle that averages only 7 hours a week in physical activity, 80% of all the women are not only obese they are also diabetic. Their counterparts in Mexico, who still eat a plant-based, whole-grain diet, are rarely diabetic and weight an average of 57 pounds less. Same genes, different lifestyle, different health pictures. Genetics loads the gun; lifestyle pulls the trigger. Slide 6: Poor Lifestyle Habits In 1900, the top three causes of death in the United States were: 1. Pneumonia/influenza 2. Tuberculosis 3. Diarrhea/enteritis. These were are infectious and communicable diseases and accounted for about 60 percent of all deaths. By 2010 the three biggest killers were: 1. Heart disease 2. Cancer 4 3. Diabetes The leading cause of death in America is not heart disease, cancer, stroke or diabetes. It is the unhealthy lifestyle that most Americans are addicted to which is the true cause. A study by Mathew Reeves, a Michigan State University epidemiologist finds that only 3% of Americans maintain a healthy lifestyle. "It is a situation that is causing dire consequences for millions of Americans. I was really quite surprised at how low that number was," said Reeves, an assistant professor of epidemiology. The research published in the journal Archives of Internal Medicine, found that only 3 percent undertook four basic steps that define a healthy lifestyle: 1. Not smoking 2. Healthy weight 3. Eating right-including a minimum of 5 fruits/vegetables a day 4. Exercising at least 5 times a week for 30 minutes. You can be a 3 percenter! All you need to do is put on the hat of responsibility and make the choice. Slide 7: The Secret Killer In February 2004 Time Magazine hailed the research that changed how we think about lifestyle diseases and pinpointed The Secret Killer. What is this secret killer? What is causing more diseases than any virus or bacteria in the world? Why is there so much heart disease, diabetes, cancer, strokes, Alzheimer’s, osteoporosis, etc.? Slide 8: The High Cholesterol Myth Let’s find out how THE SECRET KILLER was identified. In order to do that we have to go all the way back to 1961 and the huge Framingham Heart Study… What they “discovered” while studying heart disease that in many of the heart vessels they found clots and plaques. Researchers went to work identifying the contents of this clotting and plaquing and found something in common. All the plaques contained a molecule known as cholesterol. It was theorized that cholesterol, in high amounts in the blood stream, somehow stuck to the artery walls gradually clogging the blood vessels, causing an eventual closing off of the artery, or the the plaque rupturing, breaking off and forming a clot that blocked the artery downstream. In other words… heart disease and heart attacks were basically seen as a PLUMBING problem. 5 In order to fight the build up of this plaque, the low-fat diets, the roto-rooter surgeries, and the stint were developed. Later came the drugs designed to block the body’s ability to make cholesterol thus lowering the blood cholesterol levels which we call statins. How did they do? Heart disease multiplied exponentially from 1961 until now. Nothing changed. Low-fat diets did not lower heart disease; in fact, the switch to vegetable oils actually fueled the problem and made it worse. Stints prolong life but do nothing to prevent another heart attack. Statins, while successful at lowering blood cholesterol levels, do not lower the risk of heart attack or stroke. Today, over ½ of all heart attacks occur in people with normal blood cholesterol levels. Cholesterol was not and never has been the problem. In 1997 researchers at Brigham & Women’s Hospital in Boston developed a blood test called C-Reactive Protein (CRP), which they claimed roughly measured the level of inflammation in the body. They theorized that cholesterol was not the problem… that the problem was chronic inflammation of the arteries which the body was repairing and patching up by laying down a layer of protection we call plaque… the chief constituent being cholesterol. In other words, cholesterol was being made by the body to repair the damage to the blood vessel walls. They theorized that if this were true that their new blood test (CRP) would be a better indicator of heart disease than serum cholesterol levels. (they were right… men with high CRP had 3 times the number of heart attacks over a six year period that those with the lowest CRP). They were overwhelmingly correct. CRP could predict who was going to have a heart attack, where cholesterol levels really indicated nothing that was helpful. The bottom line was this… as the research continued, it was found that CHRONIC INFLAMMATION not only preceded heart disease but was also the primary risk factor for a number of diseases including: • • • • • • • • • • • • • • Alzheimer's disease Arthritis Asthma Cancer Chronic liver disease COPD Type 2 diabetes and metabolic syndrome High blood pressure Crohn's disease Nephritis or chronic renal failure Osteoporosis Stroke Depression Obesity 6 Slide 9: Inflammation: The Secret Killer The Secret Killer is chronic inflammation and it has now been shown to be a major factor in tissues throughout the body. Wherever the inflammation occurs the manifestation of inflammation is different: Blood vessels = Heart disease, stroke Joints = Osteoarthritis and Rheumatoid arthritis Skin = Eczema, psoriasis Nervous system = Multiple sclerosis, Alzheimer’s disease Pancreas = Chronic pancreatitis. Diabetes type 2 Immune system = Chronic fatigue syndrome Lungs, Bronchial tubes = Asthma Intestines = Crohn’s disease Muscle = Fibromyalgia Bones = Osteoporosis Slide 10: Inflammation: Is it Good or Bad? Acute Inflammation Just as the plants in your garden need a good mixture of sun and rain to thrive, we all need a measure of inflammation to survive. Acute inflammation is the short-term immune response our bodies mount in cases of trauma, infection, and allergy. Whether you’ve broken a bone, burned yourself on a hot stove, or been exposed to a foreign microorganism, the body is programmed to carry out a similar response. In this response, it will identify the infectious or dangerous substance, determine which cells are “self” cells (nonthreatening) and which are “non-self” cells (threatening), assess the level of the threat, mount a response, and repair any resulting damage. In a perfect world, this response occurs just as it should, releasing pro-inflammatory compounds, hormones made in every cell of the body called eicosanoids, when needed and then turning them off with anti-inflammatory compounds (eicosanoids) when the threat has been sufficiently addressed. Review the diagram Slide 11: Inflammation: Is it Good or Bad? Chronic Inflammation Chronic inflammation arises when this response is not completely turned off or extinguished. It acts like a slow-burning fire, continuing to stimulate proinflammatory immune cells when they may not be needed. What happens when these excess immune cells are circulating in our systems? They can damage healthy areas in our bodies. 7 Review the diagram, pointing out the differences from the acute process which are: 1. Continued tissue damage 2. Continued pro-inflammatory eicosanoids release 3. Continued attraction of white blood cells to “fight” and repair the damage 4. Continued cytokine release from the white blood cells attracting even more of an inflammatory response 5. And finally, the inability to shut down the inflammatory process due to lack of ability to create more anti-inflammatory eicosanoids. Slide 12: Chronic Inflammation Chronic inflammation is like a fire inside your body that never goes out and damages the cells of your body in the process leading to disease. Author Dr. Andrew Weil M.D. has written that “Chronic inflammation may be the root of ALL degenerative disease.” Slide 13: The Causes of Chronic Inflammation What are the main causes of chronic inflammation in your body: o Excessive sugar in the diet leading to high insulin levels and fluctuating blood sugar levels. o Chronic stress producing high levels of cortisol o Obesity o Omega fats imbalance in the diet o Allergies, both environmental and food allergies o Toxins from our environment o Acidic body ph We are going to go over some diagrams for the next few minutes. Please don’t get bogged down with the science or the vocabulary, the main thing that I want you to know is to understand that how you live your life either creates or reduces chronic inflammation and that chronic inflammation leads to may different diseases. This is new science which we have only just begun to understand in the last few years. In fact, I’m going to tell you something that may bother some of you in this room… If your doctor is still prescribing statins for high cholesterol and trying to bring down your cholesterol levels… if your doctor is still prescribing Fosamax, Boniva or female hormones to prevent osteoporosis… you may want to consider 8 finding another doctor. They are either still practicing in the 90’s or they haven’t taken the time to learn anything new since they graduated from medical school. Slide 14: Omega Fats and Inflammation This is probably the easiest thing for you to change starting right now… and it is one of the biggest problems with chronic inflammation today. The two essential omega fats our body must get from our food are the omega-3 and omega-6 fats. Our bodies cannot make them. Historically, when hens, livestock and dairy cows were raised on their natural foods they were very high in omega 3 fatty acids. Today, raised on man-made pellets and feed the omega-3s are nearly nonexistent. For most of the history of our planet the ratio of omega-6s to omega-3s was about 2:1, but today with less and less omega’3s available and the high use of vegetable oils (like corn oils which are high in omega-6s) the ratio has grown to be about 20:1. In fact, 60% of all American adults and 78% of American children are omega-3 deficient… it is the number 6 killer in America Why are omega-3s so important? Remember those hormone-like chemicals made by every cell in your body called eicosanoids? They play an integral part in starting the inflammation process and also in shutting it off. The proinflammatory eicosanoids that initiate the inflammation process are made from the omega-6 fatty acids and the anti-inflammatory eicosanoids that shut down the inflammation process can only be made from omega-3 fatty acids. Do you see the importance of omega-3 fats? If we don’t have enough in our diet we will be unable to shut down the inflammation process and inflammation then becomes chronic. A brand new connection to omega-3s is the production of serotonin. Serotonin is a chemical made in your brain that normalizes brain function and can lead to a sensation of well being. When there are not enough omega-3’s to produce sufficient quantities of serotonin, the result is depression. Slide 15: Omega-3 Fats and Inflammation In this diagram we see that omega-6’s are needed to start the inflammation process. The Inflammation Cascade starts with cell damage. When a cell is damaged in some way it releases a “flare” signaling the immune system to jump into action. The “flare” is the pro-inflammatory eicosanoids manufactured from omega-6 fats. The eicosanoids attract white blood cells to attack invaders and to breakdown 9 and repair any damage. If the damage is extensive or ongoing, the white blood cells release pro-inflammatory chemicals called cytokines which amplify the immune system response and attract more immune cells. If repair is not possible because of the magnitude of the damage or the ongoing assault then the inflammation process does not shut down and chronic inflammation is the result. Something important to remember is that the by products of inflammation produce exudates that are acidic and enter the lymph and blood system. Chronic inflammation can promote a lower body fluid pH. Today we get omega-6’s primarily from seeds and nuts, and the oils extracted from them. Refined vegetable oils, such as safflower, sunflower, corn and soy oil are used in most of the snack foods, cookies, crackers, and sweets in the American diet as well as in fast food. Soybean oil alone is now so ubiquitous in fast foods and processed foods that an astounding 20 percent of the calories in the American diet are estimated to come from this single source. Omega -3 fats come primarily from cold water fish and from flaxseed today. It used to be widely available in grass fed meats, poultry, dairy and eggs, but with the man-made animal feeds and loss of natural eating habits in favor of modern ranching and dairy, omega-3’s have become a rarity in our diets. Slide 17: Sugar & Inflammation Insulin is released by the pancreas after you eat carbohydrates. Eating carbohydrates causes a rise in blood sugar. Insulin assures your cells receive some blood sugar necessary for life, and increases glycogen storage. However, it also drives your body to use more carbohydrate, and less fat, as fuel. And, insulin converts almost half of your dietary carbohydrate to fat for storage. If you want to use more fats for energy, the insulin response must be moderated. Diets high in refined sugars release more insulin thereby allowing less stored fat to be burned. High insulin levels also suppress two important hormones: glucagon and growth hormone. Glucagon promotes the burning of fat and sugar. Growth hormone is used for muscle development and building new muscle mass. That means that a high sugar diet will suppress the burning of fat and the development of muscles. Insulin also causes hunger. As blood sugar increases following a carbohydrate meal, insulin rises with the eventual result of lower blood sugar. This results in hunger, often only a couple of hours (or less) after the meal. Cravings, usually for sweets, are frequently part of this cycle, leading you to resort to snacking, often on more carbohydrates. Not eating makes you feel ravenous shaky, moody 10 and ready to "crash." If the problem is chronic, you never get rid of that extra stored fat, and your energy is adversely affected. Does this sound like you? The best suggestion for anyone wanting to utilize more fats is to moderate the insulin response by limiting (ideally, eliminating) the intake of refined sugars, and keeping all other carbohydrate intake to about 40% of the diet. Generally, non-carbohydrate foods-proteins and fats-don't produce much insulin. Insulin resistance causes inflammation. As the cells of your body become “loaded” with glucose and can store no more, a mechanism will cause the “doors to lock” so that insulin will not to be able to allow glucose to enter the cell. The result is a problem called insulin resistance and causes higher and higher levels of insulin to be released to “clear” glucose out of the bloodstream and into cells in the body. 1. The sugar, having no place to go, is processed in the liver and stored as fat… however, when the fat cells begin to signal that they are also full and can store no more fat, the sugar has no place to go, it builds up in the bloodstream and spills over in the urine. We call this condition diabetes. Here’s a real important question to ask… how is diabetes usually treated today? What do you think is going to happen to a patient given more and more insulin with less and less receptors available to open the cell doors? In a 2009 study published in the journal Diabetes, researchers found that a protein called FOXO1 serves as a master switch that turns on the expression of a key inflammatory cytokine. When insulin levels are normal the FOXO1 protein is kept in check. But when a person becomes insulin-resistant and pancreatic cells no longer produce enough insulin to overcome the resistance, activity of FOXO1 increases, resulting in high inflammatory cytokine release. High levels of inflammation contribute to greater insulin resistance creating a vicious cycle. The diagram: • High amounts of sugar cause high levels of insulin to be released • With a diet of high sugar, cells become “full” of glucose and insulin levels continue to increase • Insulin resistance occurs • High insulin levels cause cell damage and signal pro-inflammatory eicosanoids starting the Inflammation Cascade • With high sugar diet, excess glucose stored as fat 11 Slide 18: The Glycemic Index Not all carbohydrate foods are created equal… they can behave quite differently in our bodies. The glycemic index or GI describes this difference by ranking carbohydrates according to their effect on our blood glucose levels. Choosing low GI carbs leads to healthy insulin levels. (Gold line in graph) Choosing high GI carbs leads to high insulin levels and fluctuating blood glucose levels that result in insulin resistance and metabolic syndrome. (Red line in graph: notice the high “spike” of blood sugar and then the drop below normal) Low blood sugar is another problem which we will talk about later. High Blood Sugar = Insulin = Chronic Inflammation = Disease Slide 19: Cortisol and Inflammation Stress signals the adrenal glands to release the stress hormone cortisol. Cortisol sends a signal to your body that it needs to prepare for a possible flight from danger. (Fight or flight syndrome) This triggers an immediate breakdown of muscle to make more blood glucose (neo-glucogenesis). To prevent nonessential organs in the body from using this precious blood glucose, a transient insulin resistance develops with a corresponding rise in insulin levels in the blood stream. Constant stress means constant secretion of cortisol. As your body adapts to chronic stress, you increase insulin, increase insulin resistance and raise blood sugar levels, therefore creating more visceral fat. This fuels a new round of cortisol secretion, and the end result is you get fatter (especially in the abdominal region) and wind up with chronic silent inflammation. The diagram: • Stress signals the adrenal glands to secrete the hormone Cortisol • Cortisol raises blood sugar and causes insulin resistance • Because of the insulin resistance an inflammatory response occurs and starts the Inflammatory Cascade Slide 20: Today’s Greatest Stress Cortisol has directed your cells to resist insulin, and keep the sugars circulating, and your body keeps putting out more and more insulin, trying to get the blood sugar levels down. The blood sugar levels fall below normal (hypoglycemia) which sends a stress signal to the brain. The result is that more cortisol is released to “deal” with the stress… increasing the insulin resistance… a vicious cycle continues. 12 Then, in an attempt to use the insulin in your blood, your body sends the signal its hungry. And you're not just hungry; you're hungry for carbohydrates - sugar. If you follow your instincts and eat carbohydrates, your body will secrete more insulin and more cortisol. And the cycle goes on and on. When sugar can no longer enter the cells of the body, it is converted by the liver into fat and is stored. Insulin resistance leads to greater and greater fat storage, but because obesity results in silent chronic inflammation which also causes even greater insulin resistance, obesity leads to diabetes. Now you can begin to see how excess sugar, chronic stress, and obesity are all connected by insulin resistance. Slide 21: Fat Cells and Inflammation Both high sugar in the diet and high cortisol levels lead to insulin resistance. Insulin resistance means that there is no place where more glucose can be stored. When that happens glucose is converted to fat in the liver and stored as fat cells. We to think of fat cells as just a blob of storage… but we now know that fat cells are not just inert cells; they are very active, producing hormones, and metabolic chemicals. When fat cells can no longer store any further fat it appears that the cells rupture and begin to leak. This leakage attracts white blood cells called macrophages which begin to release inflammatory cytokines. Diagram: • • Fat cells are very metabolically active and create and release many metabolic chemicals Note that fat cells release both IL-6 (Interleukin 6) and TNF-a (cachexin) both of which are pro-inflammatory cytokines which produce inflammation Slide 22: Fat Cells and Inflammation “Fat cells can work like immune cells, releasing pro-inflammatory proteins known as cytokines in greater and greater amounts as you gain weight. In other words, the fatter you are the more silent inflammation you generate.” Dr. Barry Sears, PhD., The Anti-Inflammation Zone Is that ever a wake-up call! 13 Slide 23: Allergies and Inflammation Allergies to foods, chemicals from the environment that we breathe, eat, drink or absorb can cause an allergic response in the body leading to chronic inflammation. Let’s use the example of gluten sensitivity or Celiac disease which is an allergy to a protein found in wheat, barley and rye called gluten. Let’s see what happens in this diagram as this gluten molecule reaches the colon, the place where approximately 80% of your immune system lies. Diagram: • • • • • • Gluten molecules reach the epithelial cells of the colon The cells sense the “intruder” and release pro-inflammatory eicosanoids as a “flare” to attract the immune cells The white blood cells in the area release pro-inflammatory cytokines to bring more white blood cells into the battle (if the person continues to eat gluten, not knowing they have an allergy, this becomes a chronic problem) Inflammation occurs and the Inflammation Cascade begins The inflammation “loosens” the junctions between the epithelial cells of the colon allowing a space for toxins to exit the colon and enter the bloodstream. This condition is called “Leaky Gut Syndrome” In this way the inflammation process can spread to any other area of the body. Whether you have an allergy to ragweed pollen or to gluten or any other allergy, the allergic response to these substances can initiate the inflammation process. If the exposure to the allergen continues, the inflammation becomes chronic Slide 24: Toxins and Inflammation What do we mean when we refer to toxins? They include: • • • • • • • • • • Cigarette Smoke Microorganisms Drugs Aluminum & Mercury Pesticides Drugs & Alcohol Household cleaners Cosmetics & personal care products Teflon Metabolic byproducts 14 • Food additives The diagram: • Toxins enter the body • All toxins are not free radicals. In fact, none of them are. Free radicals occur when toxins are absorbed into the body and the body tries to eliminate, breakdown or use those toxins within the body. Therefore, while free radicals are eventually toxic, causing cancer and other illnesses, toxins-- such as air, food and water pollution-- are not free radicals. • Free radical formation damages the cells in a chain reaction of hydrogen ions being stolen from one molecule to be added to another. This produces an acidic environment. • Cell damage initiates the Inflammatory Cascade • Acidification of the tissues results in lowered body pH levels and also initiates the Inflammatory Cascade • Lowered tissue pH results in damage to both the mitochondria, the cell membrane and DNA of the cell leading to mutations. • Mutations can lead to cancer Slide 25: Acid pH and Inflammation Normal human blood ph should be 7.365 on the ph scale. Your diet affects your body’s ph. Some foods create an acidic environment while others create an alkaline environment. Your body will be healthier with an alkaline environment. Dr. Otto Warburg won a Nobel Prize in 1931 for showing that cancer cells can multiply rapidly in an acidic environment but that cancer can not survive in an alkaline environment. The diagram: • Acidic pH leads to damage of cell membranes or the cell mitochondria initiates the Inflammatory Cascade • Chronic inflammation acidifies the tissues which can produce a vicious cycle or more acidosis and further cell damage • Acidic pH also drives the body to neutralize the acid. The body does so by taking minerals from the teeth and bones to neutralize the acid and make the tissues more alkaline. • The long term result of this is osteoporosis • In fact, chronic inflammation in the body from any other source can lead to this vicious cycle of creating more acidity, the need to alkalinize with the body’s available minerals and resulting in osteoporosis. Slide 26: Acid pH and Inflammation 15 Can we control how acidic our body is? Some of our acidity problems come from what we put in our body. • Acidic Sources: – Acidic foods • Dairy • Meat • White flour • White sugar • Vegetable oils – Soft drinks – Tobacco – Alcohol – Drugs – Water Notice on the diagram that the most acidic food in the universe is soft drinks… it is equivalent to drinking the acid from your car battery. Slide 27: Acid pH and Osteoporosis The body will try to neutralize an acidic environment by using the body’s own minerals to buffer the acid and return to a normal pH of 7.365 These minerals are “robbed” from your teeth and bones for this purpose. Over time this leads to demineralization of bone or OSTEOPOROSIS Well… what most women doing are doing to prevent and treat osteoporosis today? They are taking Fosamax, Actonel, or Boniva and they are being told that these drugs prevent bone loss, but it is a BIG LIE. Bone is living tissue that replaces itself every 7 years. Special cells called osteoclasts breakdown the old bone and other cells called osteoblasts create new healthy bone. The way these osteoporosis drugs work is that they block the breakdown of old weak bone… that way to appears on x-ray that there is more bone left. The fact is, there is more bone, but it’s just old and weak from from the drugs. Here’s the irony, the drugs are being sold to prevent osteoporosis and fractures… however, researchers in 2008 reported that these drugs so weaken the bone that hip fractures are occurring in women taking the drugs 5 years or longer from simple low impact movements such a walking up a set of stairs. 16 Slide 28: Let’s Put Out the Fire! If this chronic inflammation is behind so many of our worst health problems today what can we do to put out the fire? Slide 29: Omega-3 Fat Protocols • • • • Diet: reduce acidic foods such as meat, soft drinks, coffee, alcohol, sugars, fast foods Avoid pesticides and other toxins Eat more fish and eat only organic red meats and dairy Nutrition: – Foundational: Catalyn, Tuna Oil Omega-3 and Prosynbiotic – Functional: Tuna Oil Omega3 (2-3 grams per day (2-3 capsules Slide 30: Sugar/Insulin Protocols • • • • • Dr. Page phase I or phase II meal plan Protein 3X/day (SP Complete) Avoid insulin spikes with six meals per day Know the glycemic index of foods Nutrition: – Foundational: Catalyn, Tuna Oil Omega-3 and Prosynbiotic – Functional: Cataplex GTF (Pancreas/Insulin receptors). Paraplex (Multi-Endocrine PMG), AF Betafood, GastroFiber (Soluble fiber) Slide 31: Foods by Glycemic Index We recommend that you get a small book on the glycemic indexes of specific foods or minimally that you study about it on the internet. You’ll find some amazing things about how foods affect your insulin levels. For instance, white potatoes have a very high glycemic index, but yams and sweet potatoes are much lower. Remember, the key to maintaining a balance in your blood sugar levels and avoiding insulin spikes are to not skip meals, eat 5-6 meals a day instead of 2 or 3 big ones, and make good food choices. The glycemic index is a measure of how a food affects your insulin levels, the lower the glycemic index of the food the better it is for maintaining a balance in blood sugar and insulin. 17 I could give you a detailed list of the glycemic index of foods but this chart tells the whole story. With the exception of watermelon, if it’s processed carbs, it has a high glycemic index and creates great blood sugar fluctuations and insulin reactions. If it’s natural or whole, it has a low glycemic index and leads to healthy blood sugar and insulin levels Slide 32: Stress/Cortisol Protocols • • • • • Avoid insulin spikes – Avoid whites Plenty of rest Exercise Relaxation Nutrition: – Foundational: Catalyn, Tuna Oil Omega-3 and Prosynbiotic – Functional: Symplex M/F, Hypothalmex (General endocrine support) Adrenal Complex (Reduce cortisol resistance and dysregulation) Slide 33: Fat/Obesity Protocols • • • Lose fat – Purification program Dr. Page Phase I or II Meal Plan Exercise, especially weight training – Foundational: Catalyn, Tuna Oil Omega-3 and Prosynbiotic – Functional: SP Cleanse (Detoxification) GastroFiber (Soluble and Insoluble fiber), SP Complete (Protein shakes (3x/day) Slide 34: Allergy Protocols • • • • Elimination Diet (the long way) MRT-150 Allergy testing (the quick way) Know your Metabolic Type Nutrition: – Foundational: Catalyn, Tuna Oil Omega-3 and Prosynbiotic – Functional: Allerplex (Support for lungs, adrenal glands, liver) Antronex (Rapid liver detox, clears histamine) Slide 35: What is Your Metabolic Type • According to the Metabolic Type theory your body is genetically best suited for a certain spectrum of foods. • When you eat the wrong foods your body produces higher histamine levels, there is increased gut inflammation, destruction of the mucosal barrier in the gut, 18 decreased absorption of nutrients in the gut, imbalance of intestinal bacteria and much more… Take the Metabolic Typing test we will send you this week with your handouts and find out if you are eating for your metabolic type. Slide 36: Toxin Elimination Protocols • • • • Understand where common toxins are coming from. Switch to non-toxic products Lose weight, fat stores toxins Purification program: – SP Cleanse, GastroFiber, SP Complete, SP Greens Nutrition: – Foundational: Catalyn, Tuna Oil Omega-3 and Prosynbiotic – Functional: Cholacol I (Gallbladder), Cholacol II (Bowel), Livaplex (Liver) Slide 37: pH Balancing Protocols • • • • • Know your acid-alkaline foods. Eat 80% alkaline to 20% acidic Avoid worst acidic foods such as soda Drink neutral pH or alkaline water Test saliva pH regularly Nutritional: – Foundational: Catalyn, Tuna Oil Omega-3 and Prosynbiotic – Functional: Calcium Lactate (Ca-Mg 5:1) Organically Bound Minerals (Alkaline Ash minerals) Slide 38: Reversing Diabetes Is It Possible To Reverse Lifestyle Diseases? Thousands of diabetics have graduated from the Pritikin Longevity Center medication-free. Others leave with dosages for insulin or drugs markedly reduced. In a study of 652 Type 2 diabetics, 39% of those on insulin left the Center insulin-free. 70% of diabetics on drugs also left free of their medications. Diabetes Care, 17: 1469, 1994 Three-Week Diet/Exercise Study Shows 50% Reversal in Type 2 Diabetes at the Pritikin Longevity Center “The study shows, contrary to common belief, that Type 2 diabetes and metabolic syndrome can be reversed solely through lifestyle changes” (21 days to reverse Type 2 diabetes) Journal of Applied Physiology, April 2006 19 Slide 39: Reversing Diabetes [Video interview with Calvin by Dr. Greg Anderson] Calvin used to weigh over 300 pounds, was a medication dependent diabetic, and had rheumatoid arthritis so bad he could not walk without a cane or a walker. He used to play Santa Claus in his church because of his full white beard and big belly. Diabetes Type 2 (adult onset) currently afflicts 1 in every 5-6 Americans. More than 50% the people over age of 50 have diabetes Reversing Diabetes type 2 is not only possible; it is being done every day using some very simple principles to take your life back. Taking insulin to treat diabetes is like pouring gasoline on a fire to put it out. Diabetes is an insulin problem, and adding more insulin compounds the problem. A question I would have for any diabetic is this, “when will it become important to change your health? Now or later on when there is blood vessel damage, kidney damage, nerve damage, vision loss or when you are facing your first amputation? Slide 40: It’s Your Choice The Secret Killer is NOT a secret anymore! We know that it is causing the biggest killers in our society today. How you live your life determines your level of chronic inflammation. Are you willing to make the changes? By a show of hands, who is taking, minimally, the foundational nutritional support that every human being needs today, a multivitamin/mineral supplement, omega3s and a probiotic? Why not? At the very least, you need these things to run the metabolic processes in your body, stop the inflammation process and keep your immune system running at peak performance. Who is also taking additional nutritional support for blood sugar problems, cortisol overload or adrenal fatigue, allergies, toxin elimination or minerals to prevent acidosis in the body? 20 If you are not, here is what I want you to do. I want each of you to complete a nutritional symptom survey and have a consultation with me about how we can create a supplement regimen that is customized for your health.