NEUROETHICS NBB 470S-000 Spring 2008 Tu & Th, 1:00-2:15 p.m., 1462 Clifton Rd., Room 231 Dr. Paul Lennard 1462 Clifton Road, Suite 304 prlenna@emory.edu 404-727-4958 Office hours by appointment January 17 Introduction and Course Overview (JB) January 22 Overview of Ethics (JB) January 24 Overview of Neuroethics (PL) January 29 The Self (PL) January 31 February 5 Dr. John Banja 1462 Clifton Road, Suite 302 jbanja@emory.edu 404-712-4804 Office hours by appointment Johnson SC et al. Neural correlates of self-reflection. Brain, 2002; 125: 1808-1814. Miller BL, Seeley WW, Mychak P, Rosen HJ, Mena I, and Boone K. Neuroanatomy of the self: Evidence from patients with frontotemporal dementia. Neurology, 2001; 57:817-821. Glannon W. Bioethics and the Brain. Oxford, UK: Oxford University Press, 2007: 29-44. Free Will vs. Determination (JB) Libet B. Do we have free will? Journal of Consciousness Studies, 1999; 6:47-57. Wegner DM. Precis of The illusion of conscious will. Behavioral and Brain Sciences, 2004;27:649-659. Optional: “Aggression-related gene weakens brain’s impulse control circuits” available at: http://www.spacewar.com/reports/Aggression_Related_Gene_Weakens_Brain s_Impulse_Control_Circuits.html. Cahill L. His Brain, Her Brain. Scientific American.Com. April 25, 2005. Neurolaw (JB/PL) Tancredi L. Hardwired Behavior: What Neuroscience Reveals About Morality. New York, NY: Cambridge University Press, 2005: 46 – 68 and 143 – 161. Greely H. The social effects of advances in neuroscience: legal problems, legal perspectives. In Judy Illes (Ed.), Neuroethics: Defining the issues in theory, practice, and policy. Oxford, UK: Oxford University Press, 2006: 245 – 263. February 7 Genes on Trial (movie): February 12 Brain Readings and Lie-Detection (PL/JB) Wolpe PR, Foster KR, Langleben DD. Emerging neurotechnologies for liedetection: Promises and Perils. AJOB, 2005; 5:39-49. Ross P. Mind readers. Scientific American, Sept. 2003:74-77. Langleben, DD et al. Brain activity during simulated deception: An eventrelated functional magnetic resonance study. NeuroImage, 2002; 15:727-732. Optional: Canli T, Amin Z. Neuroimaging of emotion and personality: Scientific evidence and ethical considerations. Brain and Cognition, 2002; 50:414-431. February 14 Brain Readings and Lie-Detection (SP) February 19 Mood Manipulation (JB/PL) Glannon W. Bioethics and the Brain. Oxford, UK: Oxford University Press, 2007: 76 – 103. President’s Advisory Council on Bioethics. Beyond Therapy. Available as pdf. Chapter 5. February 21 Mood Manipulation (SP) February 26 Cognitive Enhancement (PL/JB) Glannon W. Bioethics and the Brain. Oxford, UK: Oxford University Press, 2007: 103 – 115; Murray T. Reflections on the ethics of genetic enhancement. Genetics in Medicine, 2002; 4:27S-32S. Sandel M. The case against perfection. The Atlantic Monthly, April 2004: 293: 50. February 28 Cognitive Enhancement (SP) March Brain Stimulation and Neuroprostheses 4 Foster K. Engineering the Brain. In Judy Illes (Ed.), Neuroethics: Defining the issues in theory, practice, and policy. Oxford, UK: Oxford University Press, 2006: 185-199. Naam R. More than Human: Embracing the Promise of Biological Enhancement. Broadway Press, Chapters 9 & 10 March 6 Brain Stimulation and Neuroprostheses (SP) March 11 & March 13: Spring Break March 18 Privacy (PL/JB) Kulynych J. Legal and ethical issues in neuroimaging research: human subjects protection, medical privacy, and the public communication of research results. Brain and Cognition, 2002; 50:345-357. Goldberg C. Some fear loss of privacy as science pries into brain. At http://www.cognitiveliberty.org/neuro/brain_privacy.htm. Gazzaniga M. The Ethical Brain. New York, NY: Harper Perennial, 2005: 103-119.Antisocial thoughts and the right to privacy Fedder R. To know or not to know. The Journal of Legal Medicine, 2000: 21:557-592. March 20 Privacy (SP) March 25 Neuroeconomics – group discussion Thompson C. There’s a sucker born in every medial prefrontal cortex. Oct. 26, 2003, Nytimes.com. March 27 Neuroreligion – group discussion April 1 Brain Death and Catastrophic Injuries (JB) Glannon W. Bioethics and the Brain. Oxford, UK: Oxford University Press, 2007: 148-177. Video: Coma: Four Case Studies. Films Media Group Optional: Moll J, et al. Functional networks in emotional moral and nonmoral social judgments. NeuroImage 2002: 16:696-703. April 3 Brain Death and Catastrophic Injuries (SP) April 8 Emotion and Reasoning (JB) Damasio A. Descartes Error. New York: Avon Books, 1994: ……… Greene J, et al. An fMRI investigation of emotional engagement in moral judgment. Science, 2001: 2105 – 2108. Optional: Ochsner KN, et al. Rethinking feelings: an fMRI study of the cognitive regulation of emotion. Journal of Cognitive Neuroscience, 2002;14(8):1215-1229. April 10 Emotion and Reasoning (SP) April 15 Connectionism, Prototypes and Motivated Reasoning (JB) Flanagan O. The moral network. In Robert McCauley (ed), The Churchlands and Their Critics, 1996: 192-216. Haidt J. The emotional dog and its rational tail: A social intuitionist approach to moral judgment. Psychological Review, 2001, 108:814-834. Optional: Redlawsk D. Hot cognition or cool consideration? Testing the effects of motivated reasoning on political decision making. The Journal of Politics, 2002: 64:1021 – 1044. Clark A. Connectionism, moral cognition, and collaborative problem solving. In Larry May, Marilyn Frideman, and Andy Clark. Minds and Morals. Cambridge, Mass.: MIT Press, 1998: 109-128. Kunda Z. The case for motivated reasoning. Psychological Bulletin April 17 Connectionism, Prototypes and Motivated Reasoning (SP) April 22 Animal Ethics: Dr. Marino April 24 Neuroethics: Lessons and New Directions (PL/JB) Grading: 50% - Research paper; 5-7 pages of an expanded aspect of one of your oral presentation 25% - March 18: Midterm exercise - (Three neuroethical issues; each of the three papers is to be 100-150 words) Specifics: Court case or research finding 25% = Presentations and class room discussion