T ANYA N. W EERAKKODY Department of Pediatrics University of Pennsylvania Philadelphia, PA 19104 Phone: (215) 590-7029 Fax: (215) 590-3779 Email: weerakko@mail.med.upenn.edu CURRENT POSITION PhD Candidate, Neuroscience University of Pennsylvania, Philadelphia, PA Principal Investigator: John H. Wolfe, VMD, PhD Dissertation Topic: Investigate the functional impact of neural stem transplants on endogenous neural networks. Graduation Date: Fall 2013 2007- Present EDUCATION B.S. in Neurobiology and Physiology B.S. in Psychology University of Maryland, College Park, MD Honors College GPA: 4.00/4.00, Summa Cum Laude 2007 2007 RESEARCH EXPERIENCE Eli Lilly and Company, Indianapolis, IN Research Assistant – Division of Cancer Research (laboratory of Dr. Sanduwaran Geeganage) University of Maryland, College Park, MD Research Assistant – Department of Chemistry (laboratory of Dr. Jeffrey Davis) Project Topic: Synthesized and assessed purity of compounds required for artificial ion channel assembly Project Topic: Investigated alterations to signaling pathways targeted by candidate anti-tumor agents. University of Pennsylvania, Philadelphia, PA Research Assistant – Department of Pediatrics (laboratory of Dr. John Wolfe) Project Topic: Evaluated comparative adeno-associated vector transduction efficiencies in rodent brain for three serotypes following neonatal injection. National Institutes of Health, Bethesda, MD Research Assistant– National Cancer Institute (laboratory of Dr. Liyanage Perera) Project Topic: Assessed effect of interleukin-15 overexpression on long-term immunological memory following HIV vaccine administration. 2006 2005 - 2006 2005 2002 - 2003 TEACHING EXPERIENCE University of Pennsylvania, Philadelphia, PA Certification Recipient – Center for Teaching and Learning Certificate Program 2009 - Present TANYA N. WEERAKKODY CURRICULUM VITAE Teaching Assistant – Biology 109: “Introduction to Brain and Behavior” Developed lesson plans for weekly recitations, collaborated on exam development and reviews, met with students upon request, graded written work. 1/1/2012 Coordinator – Upward Bound Outreach Program, “Introduction to Neuroscience” Developed syllabus and overall course structure, administered grades. Organized offsite visits to research laboratories and collaborated in the development of lab demonstrations and group exercises. 1/1/2012 Guest Lecturer – Upward Bound Outreach Program, “Introduction to Neuroscience” Developed lesson plans, organized small group activities, generated quizzes and homeworks. 2008 - 2010 Teaching Assistant – Biology 109: “Introduction to Brain and Behavior” 1/1/2009 University Maryland, College Park, MD Instructor – Honors 100: “Freshman Honors Colloquium” Developed syllabus and overall course structure, administered grades. 2004 - 2005 Montgomery Primary Achievement Center, Gaithersburg, MD Teaching Assistant – Special Education Program Provided specialized instruction to developmentally delayed children. Recorded progress in domains of behavioral learning, fine and gross motor skills. 2004 - 2005 MENTORING EXPERIENCE Philadelphia, PA Mentor – Minds Matter Assisted students from local high schools with summer internship applications and college/university selection. Engaged student participation in weekly debate series. University of Pennsylvania, Philadelphia, PA Mentor – Upward Bound Summer Research Program Assisted students from local high schools in the development of individual research projects. 2012 - Present 2012 - Present Leadership Committee – Secrets of Successful Scientists Workshop Series Coordinated seminars for graduate students related to their professional development. 2012 - Present Leadership Committee – Local Brain Bee Competition Helped coordinate local neuroscience competition for high school students. 1/1/2012 Undergraduate Research Mentor – Laboratory of Dr. John Wolfe 2010 - 2011 TANYA N. WEERAKKODY Mentor – ACHIEVEability Provided tutoring services to parents in low-income households seeking a postsecondary degree. CURRICULUM VITAE 2008 - 2009 RESEARCH PUBLICATIONS AND ABSTRACTS Weerakkody, T.N., Patel, T.P., Yue, C., Takano, H., Anderson, H.C., Meaney, D.F., Coulter, D.A., and Wolfe, J.H. Engraftment of non-integrating neural stem cells differentially perturbs cortical activity in a dose-dependent manner. Submitted. Weerakkody, T.N., Patel, T.P., Yue, C., Takano, H., Anderson, H.C., Meaney, D.F., Coulter, D.A., and Wolfe, J.H. (2012). Neural stem cell engraftment above a critical threshold globally reduces cortical network excitability. Abstract in Society for Neuroscience 42nd Annual Meeting, New Orleans, LA, USA. Issacman-Beck J., White, S., and Weerakkody T.N. (2012). Passing on the Passion: Exposing high school students to scientific inquiry through neuroscience. Abstract in Society for Neuroscience 42nd Annual Meeting, New Orleans, LA, USA. Weerakkody, T.N., Yue, C., Patel, T.P., Takano, H., Meaney, D.F., Coulter, D.A., and Wolfe, J.H. (2011). Functional impact of neural stem cell derived grafts on neocortical circuitry in the rodent brain. Abstract in Society for Neuroscience 41st Annual Meeting, Washington D.C, USA. Weerakkody, T.N., Yue, C., Patel, T.P., Takano, H., Coulter, D.A., and Wolfe, J.H. (2010). In vivo functional imaging of neural stem cell-derived grafts in the adult mouse cortex. Abstract in Society for Neuroscience 40th Annual Meeting, San Diego, CA, USA. Weerakkody, T.N. and Wolfe J.H. (2010) Targeting self-renewal pathways to enhance the survival and distribution of primary adult neural stem cell transplants. Abstract in Institute for Regenerative Medicine Annual Meeting, Philadelphia, PA, USA. SKILLS Molecular Biology: PCR amplification, bacterial transformation, restriction digestion, plasmid cloning, recombinant lentiviral production. Microscopy and Histology: Immunohistochemistry, epifluorescence and light microscopy, laser-scanning microscopy, voltage-sensitive dye imaging of acute brain slices, in vitro calcium imaging. In vitro and In vivo Techniques: Culturing of primary neural stem cells and stem cell lines, fluorescence activated cell sorting, in vitro transfection and transduction, neural stem cell transplantation in neonatal and adult rodents. Bioinformatics: Proficiency in ImageJ, Volocity, and Igor Software. FUNDING AWARDS AND SUPPORT T32 NRSA Developmental Biology Training Grant January 2011 University of Pennsylvania, Philadelphia, PA January 2009 – Distinguished Scholar Award January 2007 January 2003 – TANYA N. WEERAKKODY CURRICULUM VITAE University of Maryland, College Park, MD Dean’s Scholarship January 2005 University of Maryland, College Park, MD PROFESSIONAL SOCIETIES Member of the Society for Neuroscience since 2010 January 2003 –