Online Supporting Information: Clinical Conditions Considered to be indications for Considered not to be indications for antibiotic treatment antibiotic treatment Acute ear infection or mastoiditis Amoebiasis Infected animal or snake bites Appendicitis Balanitis Bartholinitis Blepharitis Brucellosis Carbuncles Cellulitis Cervicitis1 Cholera 2 Conjunctivitis Infected wounds, sores, and burns Cystitis1 Dacryocystitis Dysentery Endocarditis Endometritis Furuncles Gonorrhea Impetigo Leprosy Lymphadenitis Lymphangitis Mastitis Meningitis (non-specific)3 Osteomyelitis Paronychia3 Pelvic inflammatory disease Peptic ulcer Periapical abcess Perichondritis Pericoronitis Peritonitis1 Persistent (chronic) diarrhea3 Pertussis Plague Pleurisy3 Post-operative complications3 Pyelonephritis Pyoderma (not pyoderma gangrenosum) Pyomyositis Rheumatic heart disease Salmonellosis3 Severe Pneumonia Shigellosis Sinusitis3 Staphylococcus and streptococcus infections Abortion Acute diarrhea Acute flaccid paralysis Adult cardiovascular conditions Alcohol or drug abuse Allergies Amenorrhea Chicken pox Cirrhosis Cough Cyst4 Depression Dermatitis Diabetes Dysmenorrhea Dyspepsia Dyspnea Epilepsy Epistaxis Folliculitis4 Fungal infections GI disorders- non infective Glomerulonephritis Goiter Guinea Worm Hemorrhagic Fever Hemorrhoids Hepatomegaly Hernia Herpes HIV/AIDS5 Hydrocele Hypertension Impacted ear wax Intestinal worms Laryngitis6 Malaria Malnutrition Measles Metrorrhagia Minor dental problems Minor eye problems Mumps Musculoskeletal conditions Lymphoma Neuropathy Obstructed labor Odynophagia Oesophagitis STI (non-specific)3 Syphilis Tetanus Trachoma Trichomoniasis Typhoid Urethral discharge1 Urethritis1 Vaginitis3 1 Although Onchocerciasis Orchitis 6 Pain Palpitations Pancreatitis Papular pruritic eruption Parotitis Pemphigus Perinatal conditions in newborns Pertussis Phimosis Pharyngitis Polyps Prurigo Psoriasis Rabies Renal diseases Respiratory tract infection7 Rheumatism Scabies Schistosomiasis Sleeping sickness Spondylitis Stomatitis Trauma (non-specified) Tuberculosis 8 Tumor or cancer Ulcers (non-specified) Uritcaria Viral infection (non-specified) Vitiligo Yellow Fever the condition can be caused by a number of pathogens, bacterial causes are most common severity has not been recorded in patient records, all cases are considered indications for antibiotic treatment 3 Because diagnoses are not specified by pathogen all cases are considered indications for antibiotics 4 Unless specified as infected or necrotic, in which case antibiotic treatment is indicated 5 Cotrimoxazole should be provided as part of comprehensive HIV care, but HIV/AIDS in of itself is not an indication for other antibiotic treatment during standard visits 6 Although disease can be bacterially associated, disease is most commonly virally induced 7 Other than those specified in the left hand column 8 TB medications are not considered standard antibiotics 2 Because