Prof Dino Hadzic and Dr Lorenzo D’Antiga
This School is organized by the ESPGHAN Paediatric Hepatology Committee and is designed to provide cutting-edge information on this critical aspect of modern hepatology. The Faculty members will provide interactive sessions on the selection process, operations, complications and the long-term care of these patients, and feedback on the delegates’ cases. The School will represent an initial step in the formal educational module for young hepatologists towards
ESPGHAN Diploma in Paediatric Liver Transplantation (EDiPaeLT). This meeting should attract younger gastroenterologists and hepatologists who have an ambition to develop transplantation programs locally, but also more senior established clinicians who would like to get a state-of-the-art update in an informal setting.
Rovinj (Rovigno) is a small picturesque fishing port on the western coast of
Istria, renowned for its pleasant climate, history and art. The nearest airports are
Pula (40 min), Trieste (90 min), Venice (150 min) and Zagreb (150 min). Hotel
Lone is located on Punta Corrente beach within walking distance to the Old City.

Applications are invited for approximately 30 delegate places. Candidates should include their CV (up to 2 A4 pages) and a recommendation letter from an
ESPGHAN member. The registration fee (700 euros) will cover accommodation and tuition costs, meals and social program. Successful candidates will be expected to participate in the school with their clinical or research presentations.
Expense assistance may be sought through ESPGHAN Young Investigators Fund.
1-2 pm
U. Baumann: Explaining Criteria for ESPGHAN Diploma in PLT
JB. Otte: How did it all begin? the milestones in history of PLT)
2-2.15
2.15-3
L. D’Antiga: What is required for developing a successful PLT centre? 3-3.45
Coffee break 3.45-4.15
A Dhawan: Ethics and economics of PLT (Effects of overall healthcare/Can all countries afford PLT?) 4.15-4.45
V. McLin. Impact of pre- and peri-operative care on optimising outcome - do real
PLT contraindications exist? 4.45-5.15
Would you manage my patient differently? (interactive students’ cases) 5.15-6

D. Debray: Standard indications and timing of PLT (BA, ALF, Alagille, CF, hepatopulmonary syndrome) 8.30-9.15
D. Hadzic: Unusual indications for PLT (metabolic, mitochondrial, non-HB malignancies, immune-mediated) 9.15-10
S. Franchi-Abella: Radiological assessment before PLT 10-10.45
Coffee break 10.45-11.15
A.Dhawan: Bespoke immunosuppression: reality or fantasy?
Different anti-rejection regimes; pros and contras
11.15-12
(Bergamo-Geneva-Hannover-London-Paris) – panel discussion
1-2 Buffet lunch
12-1
N. Heaton: Surgical variations in PLT (auxiliary, LR, non-heart beating, multiorgan, domino) 2-2.45
L. D’Antiga: Multiple faces of rejection
D. Hadzic: PLT combined with other organs
2.45-3.30
3.30-4
Coffee break 4-4.30
U. Baumann: Donor selection/organ allocation; use and abuse of scoring systems.
How to be fair in an era of increasing expectations. 4.30-5
V. McLin: Approach to graft dysfunction/What can go wrong early, late and very late? 5-5.30
Would you manage my patient differently? (interactive students’ cases) 5.30-6

U. Baumann: Medical complications (prevention of viral reinfection, HEV, recurrent disease, bone marrow failure, malignancies, nephrotoxicity, social and educational issues) 8.30-9.15
S. Franchi-Abella: Interventional radiology post-PLT–don’t call the surgeon (yet)
9.15-10
N. Heaton: Surgical complications (biliary, vascular, graft remodeling, secondary
PHT) – When Prometheus met Achilles 10-10.45 rejection
Coffee break 10.45-11.15
S. Hubscher: Histopathological journey post PLT: from reperfusion to chronic
11.15-12
12-12.30 L. D’Antiga: Recurrent disease after PLT/Indications for re-LT
Buffet lunch
Trip inland Istria/wine tasting/dinner
Dhawan: Bridges and shortcuts – Stem cells, hepatocytes, gadgets and beyond
8.30-9.15
D. Debray: Ten years after PLT - state of the graft/state of the patient: resocialisation, QoL 9.15-10
JB. Otte: Documenting immunotolerance – achievable goal or dream? 10-10.30
Coffee break 10.30-11
N. Heaton: PLT in 10 years from now – what could get better? hepatology?
11-11.30
S. Hubscher: How to prepare an effective audit or successful clinical research in
11.30-12
Would you manage my patient differently? (interactive students’ cases) 12-12.30
12.30-1