Molecular and Systems Integration of Genomic and Nongenomic Steroid Hormone Action August 9- August 14, 2015 Big Sky, Montana Organizers: Donald B. DeFranco, PhD University of Pittsburgh School of Medicine Pittsburgh, PA Paul Micevych, PhD University of California, Los Angeles Los Angeles, CA Nancy Weigel, PhD Baylor College of Medicine Houston, TX Sunday, August 9, 2015 Time 4:00 p.m. – 9:00 p.m. 6:00 p.m. – 7:00 p.m. 7:00 p.m. – 8:00 p.m. 8:00 p.m. – 9:00 p.m. 10 February 2016 Plenary Event Conference Registration Welcome Reception DINNER Modulation of NFkB and Inflammation by Membrane ER signaling Christopher Glass University of California, San Diego Monday, August 10, 2015 Time 7:30 a.m. – 9:00 a.m. 7:30 a.m. – 12:00 p.m. 9:00 a.m. – 12:00 p.m. 9:00 a.m. - 9:30 a.m. 9:30 a.m. - 10:00 a.m. 10:00 a.m. - 10:30 a.m. 10:30 a.m. - 11:00 a.m. 11:00 a.m. - 11:30 a.m. 11:30 a.m. - 11:50 a.m. 11:50 a.m. - 12:00 p.m. 12:00 p.m. - 1:00 p.m. 1:00 p.m. - 4:00 p.m. 4:00 p.m. - 6:00 p.m. 6:00 p.m. - 7:00 p.m. 6:00 p.m. - 7:00 p.m. 7:00 p.m. - 9:00 p.m. 7:00 p.m. - 7:30 pm 7:30 p.m. - 8:00 p.m. 8:00 p.m. - 8:30 p.m. 8:30 p.m. - 9:00 p.m. 9:00 p.m. - 9:10 p.m. 9:10 p.m. - 9:20 p.m. 9:20 p.m. - 9:40 p.m. 10 February 2016 Title/Topic Event BREAKFAST Conference Registration Crosstalk Between Cytoplasmic Signaling Pathways and Nuclear Receptor Genomic Action Regulation of Progesterone Receptor Transcriptional Response by Plasma Membrane Signaling Crosstalk Between the Membrane and the Nucleus Impacting Glucocorticoid Receptor Function Morning Coffee Break Nuclear Receptors in Inflammation Crosstalk Between c-Src and the Estrogen Receptor Extended Discussion Poster Preview LUNCH and Meet the Speakers Free time Poster Session 1 Conference Registration DINNER Epigenetic Modulation from Membrane Steroid Receptor Signaling Developmental Regulation of Androgen Receptor Signaling by Environmental Chemicals Development Reprogramming of Cancer Susceptibility In Vivo Dynamics of Estrogen Receptor Activity Targeting Genomic and Nongenomic Estrogen Pathways for Prostate Cancer Therapy Trainee talk Trainee Talk Extended Discussion Carol Lange University of Minnesota School of Medicine Michael Garabedian New York University School of Medicine Inez Rogatsky Cornell University School of Medicine and Hospital for Special Surgery Joyce Slingerland University of Miami School of Medicine Gail Prins University of Illinois School of Medicine, Chicago Cheryl Walker Texas A&M University of Health Sciences Center Adriana Maggi University of Milan Shuk-mei Ho University of Cincinnati Tuesday, August 11, 2015 Time 7:30 a.m. – 9:00 a.m. 7:30 a.m. – 12:00 p.m. 9:00 a.m. – 12:00 p.m. 9:00 a.m. - 9:30 a.m. 9:30 a.m. - 10:00 a.m. 10:00 a.m. - 10:30 a.m. 10:30 a.m. - 11:00 a.m. 11:00 a.m. - 11:30 a.m. 11:30 a.m. - 11:50 a.m. 11:50 a.m. - 12:00 p.m. 12:00 p.m. - 1:00 p.m. 1:00 p.m. – 4:00 p.m. 4:00 p.m. – 6:00 p.m. 6:00 p.m. – 7:00 p.m. 7:00 p.m. – 9:00 p.m. 7:00 p.m. - 7:30 p.m. 7:30 p.m. - 8:00 p.m. 8:00 p.m. - 8:30 p.m. 8:30 p.m. - 9:00 p.m. 9:00 p.m. - 9:10 p.m. 9:10 p.m. - 9:20 p.m. 9:20 p.m. - 9:40 p.m. 10 February 2016 Title/Topic Event BREAKFAST Conference Registration Steroid Signaling in the Brain ERE-Independent Signaling of E2 and Control of Neuronal Homeostasis Synaptic Regulation of the Hypothalamic-Pituitary-Adrenal Axis and its Modulation by Glucocorticoids and Stress Morning Coffee Break and Group Photo Neural Plasticity in Neuroendocrinology Astrocyte Steroidogenesis and E2 Feedback on GnRH Neurons Extended Discussion Poster Preview LUNCH and Meet the Speakers Free time Poster Session 2 DINNER Rapid Actions of Steroids on Ion Channels Estrogen Regulation of Epithelial Ion Transport: Implications in Health and Disease Anti-diabetic Actions of an Estrogen Receptor Selective Agonist Aldosterone Regulation of Renal Chloride Transporters Regulation of ENaC by Steroid Hormones Trainee talk Trainee talk Extended Discussion Jon Levine University of Wisconsin Jeff Tasker Tulane University Catherine Woolley Northeastern University Paul Micevych UCLA Brian Harvey Royal College of Surgeons in Ireland Angel Nadal Miguel Hernandez University of Elche Carsten Wagner Zurich Center for Integrative Human Physiology Michael Butterworth University of Pittsburgh Wednesday, August 12, 2015 Time a.m. – Time p.m. 7:30 a.m. – 9:00 a.m. 7:30 a.m. – 12:00 p.m. 9:00 a.m. – 12:00 p.m. 9:00 a.m. - 9:30 a.m. 9:30 a.m. - 10:00 a.m. 10:00 a.m. – 10:30 a.m. 10:30 a.m. - 11:00 a.m. 11:00 a.m. - 11:30 a.m. 11:30 a.m. - 11:50 a.m. 11:50 a.m. - 12:00 p.m. 12:00 p.m. – 12:30 p.m. 12:30 p.m. – 2:00 p.m. 2:00 p.m. – 4:00 p.m. 4:00 p.m. – 6:00 p.m. 6:00 p.m. – 7:00 p.m. 7:00 p.m. – 9:00 p.m. 7:00 p.m. - 7:30 p.m. 7:30 p.m. - 8:00 p.m. 8:00 p.m. - 8:30 p.m. 8:30 p.m. - 9:00 p.m. 9:00 p.m. - 9:10 p.m. 9:10 p.m. - 9:20 p.m. 9:20 p.m. - 9:40 p.m. 10 February 2016 Title/Topic Event BREAKFAST Conference Registration Integrative Steroid Hormone Signaling in Cancer-I New links Between Cell Cycle Regulators and Androgen Receptor Action in Prostate Cancer Steroid Hormone Receptor Signaling in Prostate Cancer Morning Coffee Break Cell Surface Receptor-Initiated Actions of Thyroid Hormone on Gene Expression in Tumor Cells Estrogen Modulation of Metabolic Pathways in Breast Cancer Extended Discussion Poster Preview Business Meeting LUNCH and Meet the Speakers/Expert Free time Poster Session 3 DINNER Integrative Steroid Hormone Signaling in Cancer-II Novel Estrogen Receptor Ligands Estrogen-Related Receptor, Energy Metabolism and Cancer Crosstalk Between Membrane Signaling and Androgen Action in Prostate Cancer Pre-Clinical Studies of Epigenetic Therapies Targeting Histone Modifiers in Lung Cancer Trainee talk Trainee talk Extended Discussion Karen Knudsen Jefferson College of Medicine Nancy Weigel Baylor College of Medicine Paul Davis Ordway Institute Ellis Levin VA Medical Center, Long Beach John Katzenellenbogen University of Illinois Donald McDonnell Duke University Steven Hammes University of Rochester Elisabeth Martinez University of Texas Southwestern Medical Center Thursday, August 13, 2015 Time a.m. – Time p.m. 7:30 a.m. – 9:00 a.m. 9:00 a.m. – 12:00 p.m. 9:00 a.m. - 9:30 a.m. 9:30 a.m. - 10:00 a.m. 10:00 a.m. - 10:30 a.m. 10:30 a.m. - 11:00 a.m. 11:00 a.m. - 11:30 a.m. 11:30 a.m. - 11:50 a.m. 12:00 p.m. - 1:00 p.m. 1:00 p.m. – 6:00 p.m. 6:00 p.m. - 7:00 p.m. 7:00 p.m. - 9:00 p.m. 7:00 p.m. - 7:30 p.m. 7:30 p.m. - 8:00 p.m. 8:00 p.m. - 8:30 p.m. 8:30 p.m. - 9:00 p.m. 9:00 p.m. - 9:10 p.m. 9:10 p.m. - 9:20 p.m. 9:20 p.m. - 9:50 p.m. 10 February 2016 Title/Topic Event BREAKFAST Steroid Hormone Control of Cardiovascular Function Estrogen Receptor Mediated Gprotein Signaling and Angiogenesis Impact of Glucocorticoids on Heart Development Morning Coffee Break Mineralocorticoid Receptor and Cardiac Arrhythmia Membrane-Initiated Actions of Estrogen on the Endothelium Extended Discussion LUNCH and Meet the Speakers Free time Special Event: DINNER Regulation of Energy Metabolism by Nuclear Hormone Receptors Estrogen K+ Channels and Homeostasis Metabolic Impact of Sex Hormones on Obesity Estrogen, Astrocytes and the Neuroendocrine Control of Metabolism An Acetylation Rheostat for the Control of Muscle Energy Homeostasis Trainee talk Trainee talk Extended Discussion Phil Shaul University of Texas Southwestern Medical Center John Cidlowski NIEHS Frederic Jaisser Universite Pierre et Marie Curie Jeffrey Bender Yale University Martin Kelly Oregon Health Sciences University Deborah Clegg University of Texas Southwestern Medical Center Matthias Tschop Helmholtz Zentrum Munchen and Department of Medicine Johan Auwerx Ecole Polytechnique Federale de Lausanne Friday, August 14, 2015 Time a.m. – Time p.m. 7:30 a.m. – 9:00 a.m. 9:00 a.m. Title/Topic Event BREAKFAST Boxed Snacks to Go And DEPARTURES END OF CONFERENCE For additional information contact: FASEB Science Research Conferences 9650 Rockville Pike Bethesda, MD 20814 www.faseb.org/src 10 February 2016