THE UNIVERSITY OF NOTTINGHAM ROLE PROFILE FORM Job Title: Research Fellow (fixed-term) School/Department: School of Medicine, Radiological Sciences Salary: £28,982 - £37,768 per annum, depending on qualifications, skills and experience. Salary progression beyond this scale is subject to performance. Job Family and Level: Research and Teaching Level R&T4 Contract Status: The post is available from 1 August 2016, and will be offered on a fixed term contract for 2.5 years. Hours of Work: Full-time – 36.25 hours per week Location: Queen’s Medical Centre Campus, University of Nottingham Reporting to: Professor of Neuroimaging Division of Clinical Neuroscience, Purpose of the Role: The main role of this post is to support the Nottingham ARUK Pain Centre’s imaging research activities. This includes advanced magnetic resonance imaging research into the mechanisms of pain progression in people with osteoarthritis. The postholder will also develop and facilitate expansion of the imaging research programme and support training of MSc, PhD students as part of the ARUK Pain Centre’s training progamme. Research focus on interventions to modulate brain network activity is particular encouraged. Collaboration with the wider membership of the ARUK Pain Centre, the Sir Peter Mansfield Imaging Centre and the Translational Neuroimaging Centre in Mental Health is strongly encouraged. Main Responsibilities 1. 2. 3. 4. % time per year Undertake neuroimaging research into understanding the neural mechanisms of pain progression in osteoarthritis pain. Develop imaging biomarkers of pain progression in OA. This involves contribution to research governance, MR protocol refinement, organisation and support of MR scanning, data handling, advanced image analysis, presenting results in conferences and peer-reviewed journals. Develop strong collaborative links with / and pro-actively support collaborate research with all involved research teams across the ARUK Pain Centre including joint grant applications. Contribute to effective communication with the wider scientific community, public and Arthritis Research UK. Other duties appropriate to the grade and role of the person appointed. You are expected to make a contribution to teaching that is in balance with wider contributions to research and other activities. Recruitment 60% 20% 10% 10% Essential PhD in neuroscience, neuroimaging or related subject Qualifications/ Education Skills/Training Good understanding of principles of MR imaging and including fMRI of the brain Very good knowledge of major image analysis packages (SPM, FSL, AFNI, Freesurfer, REST) Ability to design fMRI studies and phantom studies for quality control and data analysis. Ability to independently perform advanced brain network analysis Experience Other Several years’ experience in acquiring and analysing MRI data Experience with imaging based brain network analysis Presentations at international conferences. Publication in leading peerreview journal. Several first author peerreviewed publications. Excellent IT skills. Excellent organisational skills. Excellent communications skills. Ability to work in a multidisciplinary research team Willingness to adopt the Ethos and Principles of the School of Medicine to improve the student experience. Desirable Specific training or qualification related to advanced brain imaging analysis including machine learning and effective connectivity analysis. Understanding of clinical and research governance related to imaging studies. Understanding of major mental health disorders and their effects on brain network dysfunction Understanding of central pain processing Experience in running research projects MRI research in patients. Experience in mental health and pain questionnaires Experience in pain phenotyping Decision Making i) Taken independently by the role holder; decisions regarding protocol optimisation and image quality assurance testing decisions relevant to the day-to-day smooth running of the project, within the requirements of Good Clinical Practice decisions regarding data quality assessment and analysis methodologies ii) Taken in collaboration with others; decisions regarding overall protocol content decisions regarding inclusion of cases or exclusion of data decisions regarding patient / participant pathways decisions regarding ethical amendments or protocol amendments after commencement of the study decisions regarding content of papers and conference abstracts decisions regarding direction of students and collaborations decisions regarding proposals for funding applications decisions regarding long-term research programme and future collaborative research Page 2 of 5 decisions regarding design and hardware implications of data repository iii) Referred to the appropriate line manager by the role holder Wider strategy of the research group Purchase decisions Additional Information The Arthritis Research UK Pain Centre at The University of Nottingham investigates the mechanisms that lead to the chronic pain experienced by sufferers of arthritis, in order to improve the treatment of that pain. Radiological Sciences is part of the Division of Clinical Neurosciences, School of Medicine, and its research group members are also members of the newly launched Sir Peter Mansfield Imaging Centre (SPMIC) bringing together MR physicists, Imaging scientists, academic Radiologists and other clinical academics interested in imaging biomarker research. The post holder will work closely with the ARUK Pain Centre, Radiological Sciences and the Neuroimaging community across the University/ Sir Peter Mansfield Imaging Centre. Appendix 1 The University of Nottingham The University of Nottingham is a global-leading, research-intensive university with campuses in the UK, Malaysia and China. Our reputation for world-class research has yielded major scientific breakthroughs such as Nobel-winning MRI techniques, drug discovery, food technologies and engineering solutions for future economic, social and cultural progress. Already ranked among the UK’s elite universities and global polls for research excellence, our reputation for world-class research has been further enhanced with the 2014 results of the Research Excellence Framework (REF). In addition to scoring highly in quality rankings covering major disciplines in science, engineering, the social sciences, medicine, business and the arts, it is Nottingham’s research power rankings which demonstrate the impressive volume of excellent research which is carried out. We are now ranked 8th in the UK on a measure of ‘research power’ which takes into account both the quality of research and the number of research-active staff who made REF returns, confirming Nottingham’s place in the top tier of the world’s elite higher education institutions. The main University campus is set beside a lake, in an extensive belt of woodland, parks and playing fields. The 330 acre University Park Campus is the focus of life for more than 32,000 students and houses the majority of the University’s academic schools and many of the central Services. The Jubilee campus is situated 2 miles away from the University Park, and provides extra capacity. The University Medical School is situated next to the University Park. Together with the University Hospital, it forms the Queen’s Medical Centre (QMC). University of Nottingham Medical School Nottingham has a strong reputation for both clinical medicine and teaching. As one of the most popular medical schools in the country, it is able to select excellent students and produce and attract good junior doctors. The School of Medicine was formed following Faculty reconfiguration on August 1st 2013. The new School of Medicine comprises the Divisions of Cancer and Stem Cell Sciences, Child Health, Obstetrics and Gynaecology; Clinical Neuroscience; Epidemiology and Public Health; Primary Care; Psychiatry and Applied Psychology; Rehabilitation and Ageing; Medical Sciences and Graduate Entry Medicine; Respiratory Medicine; Rheumatology, Orthopaedics and Dermatology and the Nottingham Digestive Diseases Centre. The School also hosts the Medical Education Centre, the Centre for Interprofessional Education and Learning, the Clinical Research Facility, the Clinical Skills Centre, NIHR design Service East Midlands, Nottingham Clinical Trials Unit, PRIMIS and Medical Imaging Unit. Page 3 of 5 The new School of Medicine brings together in one School staff undertaking research for the benefit of the health of patients. It includes all primary care and hospital-based medical and surgical disciplines, principally in the Queen’s Medical Centre and City Hospital Nottingham Campuses, Royal Derby Hospitals NHS Foundation Trust and also at the University’s main campus and at the King’s Meadow and Jubilee Campuses. Most of our School’s Senior Researchers and Teachers are also clinicians who dedicate 50% of their time to patient care within the Nottingham University Hospitals NHS Trust & Royal Derby Hospitals NHS Trust. This close juxtaposition brings cutting-edge clinical care to our patients and clinical relevance to our research and teaching. We are closely integrated with our full time NHS clinical colleagues, many of whom are themselves leaders in research and teaching and who work closely with the University and this increases the mutual benefit from integration between the University and NHS. Mission: Our mission is to improve human health and quality of life locally, nationally and internationally through outstanding education, research and patient care. Priorities: 1. Teaching and learning, particularly training tomorrow’s doctors and teaching specialised postgraduates 2. Research and research training: We will perform and support the highest quality “big” research which impacts on human health and disease 3. Partnership with the NHS and other healthcare providers 4. Visibility and profile of the School of Medicine: We will do what we do better, and we will tell others about it Ethos and principles: 1. Having people and patients at the heart of all we do: our teaching and learning, our research and our patient care 2. Contribution within the School of Medicine and to society beyond our immediate roles; helpfulness and service 3. Openness and fairness, with particular emphasis on communication (both internal and external) and on equality and diversity among students and staff 4. Personal and group responsibility for all aspects of our work, within a culture of opportunity and reward Our research spans 11 major themes, ranging from cancer to vascular medicine. We work closely with industry and the NHS. Our world-leading research ranges from basic and translational science through to clinical trials, epidemiology, and health services research. Our clear theme is improving human health, underpinning a vibrant postgraduate research training programme leading to PhD or DM. Many of our academics are clinicians, using their expertise to provide cutting edge specialised treatment to NHS patients; reflecting our ethos that patients are at the heart of all we do. In the 2014 Research Excellence Framework the four Units of Assessment included in the School of Medicine were among the six most improved in the whole University since RAE 2008: Over 80% of our research in 2014 was graded as world-leading or internationally excellent. Our research spans 11 major themes and ranges from basic and translational science through to clinical trials, epidemiology, and health services research. We work closely with industry and the NHS. Our research is underpinned by a strong postgraduate research training programme leading to PhD or DM. Our major research themes are in Cancer and Stem Cells; Child Health, Obstetrics & Gynaecology; Clinical Neurosciences; Dermatology; Digestive Diseases; Epidemiology and Public Health; Mental Health; Musculoskeletal physiology and disease; Primary Care; Rehabilitation and Ageing; Respiratory Medicine; and Renal Medicine. The School of Medicine trains tomorrow’s doctors on a vibrant undergraduate medical course with a unique intercalated BMedSci, as well in a specialised graduate-entry programme built around clinical problem solving. We teach medicine and related disciplines at both undergraduate and postgraduate level. We have a dedicated clinical academic training programme and are committed to training PhD and doctoral research students and to supporting postdoctoral clinicians and scientists in their research. Page 4 of 5 The School of Medicine holds a Bronze Athena SWAN award in recognition of our commitment to advance the representation of women in science, technology, engineering, medicine and mathematics (STEMM). The award reflects our commitment to promoting equality and diversity. Please see http://www.nottingham.ac.uk/medicine/about/athena-swan.aspx. Professor John Atherton is Dean of the School of Medicine. For further information, please see our website http://www.nottingham.ac.uk/medicine Nottingham Central within the East Midlands, Nottingham is a vibrant and prosperous city with something to offer everyone. It is one of the UK’s leading retail centres and has a huge variety of restaurants, bars and nightclubs which attract people from all over the UK. Culturally, it has good theatres, an arena which attracts both national and international performers and a range of historical interests relating to subjects such as the lace industry, Lord Byron and DH Lawrence. Nottingham is also known for sport, being the home of Trent Bridge Cricket Ground, Nottingham Forest and Notts County Football Clubs, the National Water Sports Centre and the Nottingham Tennis Centre. There is a good network of roads with easy access to the M1 and the A1, a fast frequent rail service to London and other major cities. Nottingham East Midlands Airport is only eighteen miles away. The city is set within a county of outstanding natural beauty which includes Sherwood Forest, Wollaton Park, lively market towns and wonderful historic buildings. Housing is relatively inexpensive and, in addition to the two Universities, there are excellent schools and colleges available. To find out more about Nottingham, use the following links: Nottingham County Council – Tourism http://www.experiencenottinghamshire.com/ University of Nottingham http://www.nottingham.ac.uk Zoopla (Guide to local properties) http://www.zoopla.co.uk/ My Nottingham (information on schools, term dates, school transport etc.) http://www.nottinghamcity.gov.uk/index.aspx?articleid=8524 Page 5 of 5