BIOGRAPHICAL SKETCH Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME POSITION TITLE Richard A Jones Assistant professor of Radiology, Emory University. eRA COMMONS USER NAME RAJONES1 EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) DEGREE INSTITUTION AND LOCATION (if YEAR(s) FIELD OF STUDY applicable) University of Nottingham, UK BSc 1977-1980 Physics University of Aberdeen, UK MSc 1982-1983 Medical Physics AVH, Trondheim, Norway PhD 1988-1991 Medical Physics A. Personal statement. With over 20 years experience in MRI I have expertise in a range of MRI techniques, have previously worked on contrast enhanced applications for the lung and have extensive experience with image post-processing. B. Positions and Honors. Positions and employment 1981-1982. Engineer 1983-1988. Research assistant 1988-1995. Research scientist 1995-1997. Senior scientist 1998-2001. Senior researcher 2001-Pres. Assistant professor British Telecom, London, UK Dept. of Medical Physics, University of Aberdeen, UK MRI Centre, SINTEF, Trondheim, Norway Dept of Radiology, Max Planck Inst. for Psychiatry, Munich, Germany. RMSB, University of Bordeaux, France. Dept. of Radiology, Emory University School of Medicine, Atlanta, GA. Professional membership Member; International Society for Magnetic resonance in Medicine (ISMRM) Reviewer for Magnetic resonance in Medicine, Journal of magnetic resonance imaging and Journal of Urology. Honours NHS scholarship (1982-1983) EU Marie Curie Senior researcher scholarship (1998-2000) FMR (Foundation for medical research); Research award (2000-2001) SPR Caffey Award (2002). SPR Berdon Award (2003). SPR Caffey Award (2007). C. Selected peer-reviewed publications 1. TW Redpath and RA Jones (1988). FADE: a new fast imaging sequence. Magn. Reson. Med. 6,224-234. PMC Journal – in process 2. Jones RA and Southon TE (1992). Improving the contrast in rapid imaging sequences with pulsed magnetisation transfer contrast. J. Magn. Reson. 97, 171-176. PMC Journal – in process 3. RA Jones, O Haraldseth, TB Müller, PA Rinck and AN Øksendal (1993). K-space substitution: A novel dynamic imaging technique. Mag. Res. Med. 29,830-834. PMC Journal – in process 4. RA Jones, O Haraldseth, AM Baptista, TB Müller and AN Øksendal (1996). A study of the contribution of changes in the cerebral blood volume to the haemodynamic response to anoxia in rat brain. NMR in Biomedicine, 9, 233-240. PMC Journal – in process 5. RA Jones, T Schirmer, B Lipinski, GK Elbel and DP Auer (1998). Signal undershoots following visual stimulation: A comparison of gradient and spin echo BOLD sequences. Magn. Reson. Med. 40, 112-118. PMC Journal – in process 6. RA Jones (1999). Origin of the signal undershoot in BOLD studies of the visual cortex. NMR in Biomed. 12, 299-308. PMC Journal – in process 7. KKW Kampe, RA Jones, DP Auer (2000). Frequency Dependence of the Functional MRI Response after Electrical Median Nerve Stimulation. Human Brain Mapping. 9, 106-114. PMC Journal – in process 8. M Ries, RA Jones, V Dousset, CTW Moonen (2000). Diffusion tensor imaging of the spinal cord. Magn. Reson. Med 44, 884-892. PMC Journal – in process 9. RA Jones, M Ries, CTW Moonen, N Grenier (2002). Imaging the changes in renal T1 induced by the inhalation of pure oxygen : a feasibility study. Magn. Reson. Med. 47, 728-35. PMC Journal – in process 10. RA Jones, S Palasis, JD Grattan-Smith (2003). The evolution of the ADC in the pediatric brain at low and high diffusion weightings. J. Magnetic. Reson. Imaging. 18(6): 665-674. PMC Journal – in process 11. RA Jones, JD Grattan-Smith, S Palasis (2004). MRI of the neonatal brain : Optimisation of spin-echo parameters. Am. J. Roentgenol. 182(2) 367-72. PMC Journal – in process 12. RA Jones, MR Perez-Brayfield, A Kirsch, JD Grattan-Smith (2004) . Renal transit time using MR urography: classification of obstructive uropathy in children. Radiology. 233: 41-50. PMC Journal – in process 13. RA Jones, K Easley, SB Little, H Scherz, AJ Kirsch, JD Grattan-Smith (2005). Dynamic, contrast enhanced, MR urography in the evaluation of pediatric hydronephrosis. Part 1: Functional assessment. Am. J. Roentgenol. 185(6):1598-1607. PMC Journal – in process 14. GR Kirk, MR Haynes, S Palasis, C Brown, TG Burns, RA Jones (2009). Regionally specific cortical thinning in MRI negative children with sickle cell disease. Cerebral Cortex. 19 (7): 1549. PMID: 18996911 15. RA Jones, JD Grattan-Smith, S Little (2011). Pediatric MR Urography. J. Magn. Reson. Imaging 33:510– 526. PMC Journal – in process D. Research Support Previous support (2005-2010) Siemens : PI. Using DTI to investigate laterality and connectivity in pediatric epilepsy patients. A study to investigate the use of a non-invasive technique (DTI) to assess language laterality in sedated patients. (20072009) CHOA: PI. Radiology Research grant. Anatomical correlates of cognitive impairment in pediatric sickle cell patients. A study using morphometry, diffusion and fMRI, to assess changes in the brain of adolescents with sickle cell disease. (2008-2010) CROC : Co-PI. Executive Function in Children Diagnosed with Frontal Lobe Epilepsy and Sleep Disordered Breathing: A Correlation of Neurocognitive Skills and Cortical Thickness. Study to examine the correlation between executive function and cortical thickness in two clinical populations suspected of having executive skills deficits. (2007-2009) CHOA : PI. Radiology Research grant. MRI of macrophage activity in an animal model of partial uretero-pelvic junction obstruction. A study to determine the feasibility of using iron oxide contrast agents as a marker for UPJ obstruction. (2007-2010) Current support Siemens : PI. Dynamic MR urography. Development of pulse sequences, protocols and processing software for MR urography in children. Development of software and protocols to help with the dissemination of MR urography techniques in the pediatric imaging community. Effective 2007, CHOA : PI. Radiology Research grant. Cerebro-renal disease? A morphometric study of the brains of pediatric patients with chronic renal insufficiency. A study to use advanced imaging techniques, including morphometry, diffusion tensor imaging and resting state fMRI to assess changes in the brain of adolescents with chronic kidney disease. Effective 2009. CROC : PI. A novel treatment regime and optimized imaging protocol to permit non-sedate MRI studies of autistic individuals. Effective 2010