2/24- Notes on DNA Ch 6 DNA stands for deoxyribonucleic acids. It is found in the nucleus. It is known as the “double helix” or the “spiral staircase” DNA is made up of bases; rungs (steps) or nucleotides (nitrogen bases) Complimentary bases A- goes always with T, C will always pair up with G. This is called replication(unzipping stage) making and pairing with new bases. Adenine (A) pairs with Thymine (T) and vice versa/ cytosine (C) pairs always with guanine.(G) Draw a spiral.. now make the bases: A-T, C-G ___? -A-T- ____? (saying… “At the guys club”) DNA is the ”blue print” of WHO YOU ARE! YOU ARE UNIQUE only IDENTICAL TWINS have the exact DNA. Watson and Crick? What did they do? They formed the model for how DNA looks/ a double helix. Who is Rosalind Franklin? She found DNA looking at an x-ray (diffraction) How was DNA first discovered? Looking at an X-ray diffraction off the DNA molecules. Showing spiral like shape. Chargaff’s Rules: (%) How the bases pair up; A-T, C-G, so the amount of each base will equal its’ complementary paired base: A=50%, T= 50% Why is DNA important? Crime solving/ finding out about who is the parents/offspring. RNA- Notes: RNA stands for ribonucleic Acids. They make proteins. If you have NO proteins you have no cell! There are mRNA (messenger RNA) and tRNA (transfer RNA) *** Look at Mr Parr DNA on YOU TUBE 3 bases =1 codon (code for a protein). 1 codon=1 amino acid: Proteins are made from amino acids (building blocks) BASES for RNA are: A, U, C, G Uracil is there instead of thymine- THERE IS NO THYMINE… So Adenine MUST pair up with Uracil!! So if you make a DNA sequence of: A-T-C-C-G-G-A-A-T What would be the RNA coding for a protein be? (Match the bases but remember RNA’s bases are: A, U, C, and G (THERE IS (NO THYMINE/ RNA has replaced it with “U”- uracil) so what will Adenine pair up with now when we make an RNA/ protein strand?