The ACID FAST CLUB Summer Meeting 2014 Our 60th celebratory meeting will be held on Thurs/Friday 10th /11th July 2014 At Kaiserin Friedrich-Haus Robert-Koch-Platz 7 Berlin Germany Local Hosts: Stefan H. E. Kaufmann & Robert Golinski Max Planck Institute for Infection Biology Programme Thursday 10th July: Berlin Mini Symposium, Aeras and offered papers 13:40 - 15:40 Session 1: Welcome, Berlin + Aeras Special 15:40 – 16:30 Refreshments and AFC Members Business Meeting 16:30 - 18:00 Session 2: Offered Papers 1 and History of AFC 18:00 - 19:00 Champagne/Wine reception 19:00 – Celebratory dinner at Sarah Wiener depending on numbers (http://www.sarahwiener.de/) Friday 11th July: Acid Fast Club offered papers 9:30 – 11:10 Offered Papers 2 11:10 – 11:40 Refreshments 11:40 – 13:20 Offered papers 3 13:20 - 14:30 Lunch 14:30 - Visit to the Robert Koch Institute (25 people max) Nominations The following nomonations for memberships have been received: Elena Stylianou, University of Oxford, proposed by Helen McShane, seconded by Rajko Reljic Maximiliano Gutierrez, NIMR, nominated by Brian Robertson, seconded by Douglas Young Luiz Pedro Carvalho, NIMR, nominated by Kristine Arnvig, seconded by Teresa Cortes Domestic arrangements Wine and soft drinks will be served at 18:00 on Day 1 at Kaiserin Friedrich-Haus, all participants are welcome! Dinner 19:00 Day 1 Celebratory dinner for up to 65 people (operated on a first come first serve basis with priority for members). Details will be circulated later. For those who prefer to make their own dinner arrangements, there are plenty of restaurants of all categories around. Lunch Day 2 Lunch is not provided. However, there are many restaurants, sandwich bars and coffee shops in the vicinity. Visit to Robert Koch Institute 14:30 Day 2. Our hosts have arranged a visit to the original Robert Koch Institute. However, this tour can accommodate a maximum of 25 people; again operated on a first come first serve basis with priority for members. Aeras socializing before the meeting We are also planning an informal social event with people from Aeras who are in Berlin, on the evening before the meeting (Wednesday) in case you want to schedule arrival to fit around this. Getting To Kaiserin Friedrich-Haus AIR: BERLIN HAS TWO INTERNATIONAL AIRPORTS TEGEL (TXL) AND SCHÖNEFELD (SXF), Ground transportation from Berlin Tegel (TXL) Airport 1) Bus line "TXL" (every 7mins): 20 mins ride, 2.60 € (driver sells ticket). Get off at "Hauptbahnhof" and follow map (7mins walk). 2) Taxi: 20 mins ride, approx. 20 € Ground transportation from Berlin Schönefeld (SXF) Airport 1) Regional train lines "RE7" or "RB14" (approx. every 30 mins): 35 mins ride, 3.20 € (ticket must be bought beforehand at machines). Get off at "Berlin-Friedrichstrasse" and walk down Luisenstrasse (see map, 10mins). 2) Taxi: 45 mins ride, approx. 65€ Accommodation Suggestions for accommodation below. Special rates still apply for Hotel Aquino (exclusively via phone or email) until May 7th with code MPI. Hotel Aquino www.hotel-aquino.de Mercure Hotel Berlin City http://www.mercure.com/gb/hotel-5341-mercure-hotel-berlin-city/index.shtml. Hotel Allegra www.albrechtshof-hotels.com ‘Info about things to do in Berlin for ideas on how to spend your Friday afternoon, or weekend if you are staying longer will be circulated independently. Programme Thursday 10th July: Berlin Mini Symposium, Aeras and offered papers Session 1: Welcome, Berlin + Aeras Special Welcome by Glyn Hewinson TB Research in Berlin Spanning 130 Years, Stefan Kaufmann, Max Planck Institute for Infection Biology Interferons, Inflammation and Lung Injury in TB, Anca Dorhoi, MPIIB Molecular profiling for host biomarker discovery in health and disease, Jeroen Maertzdorf, MPIIB Individuality in disease: patient-specific and cell-specific gene expression in TB, January Weiner, MPIIB Title to come, Tom Evans, Aeras 16:30 - 18:00 Session 2, Offered Papers Speakers are underlined & their affiliation indicated Metabolic models of mycobacteria: systems insights into pathogenesis, Johnjoe McFadden, University of Surrey Transcriptome analysis reveals differential innate immune response of bovine macrophages to strains of the Mycobacterium tuberculosis complex, Kevin Rue-Albrecht, David A. Magee, Kevin M. Conlon, Nicolas C. Nalpas, John A. Browne, Paul A. McGettigan, Claire Healy, Kirsten E. McLoughlin, Eamonn Gormley, David E. MacHugh and Stephen V. Gordon, University College Dublin Tetrahydrobiopterin production by macrophages is not required for protective immunity to Mycobacterium tuberculosis, Elena Stylianou, Eileen McNeill, Rachel Kandt, Keith Channon, Helen McShane, The Jenner Institute, University of Oxford A brief history of the Acid Fast Club, Ann Rawkins, Public Health England, Porton Down Friday 11th July: Acid Fast Club offered papers Session 1 Degradosome as one of the major RNA processing complexes in Mycobacteria, Przemyslaw Plocinski, Maria Macios, Emilia Niemiec, Joanna Houghton, Douglas Young and Andrzej Dziembowski, Institute of Biochemistry and Biophysics Polish Academy of Sciences NO biomarker for TB - Expired nitric oxide and lipid body content of tubercle bacilli in sputum, Baye Gelaw, Natalie J. Garton, Gashaw Mesele, Tadye Abeje, Salie Ayalew, Pranabashis Haldar, Abraham Assefa, and Michael R Barer, Department of Medical Microbiology, CMHS, UOG, Ethiopia Whole genome sequencing of Mycobacterium tuberculosis from sputum: a revolution in diagnostic microbiology, Amanda Claire Brown and members of the PathSeek project consortium, Oxford Gene Technology Characterisation of host genetic factors that influence pathogen-host interplay during Mycobacterium tuberculosis infection, K. M. Kreutzfeldt, L. Mullen, C. Finan, S. J. Waddell, A. Marchant, M. J. Newport and S. M. Sacre, Brighton & Sussex Medical School, University of Sussex The use of gene expression profiling in Mycobacterium tuberculosis as a tool to study drug efficacy and action, Dimitrios Evangelopoulos, Aidan Hanrath, Iva Treveska, Magdalena Karlikowska, Isobella Honeyborne, Sanjib Bhakta, Simon Waddel, Philip Butcher and Timothy D. McHugh, Centre for Clinical Microbiology, Royal Free Campus, University College London Session 2 Development of a BCG challenge model for the testing of vaccine candidates against bovine tuberculosis, Villarreal-Ramos, B., Berg, S., Chamberlain, L., McShane, H., Hewinson, R. G., Clifford, D., Vordermeier, M., Bovine TB Group, AHVLA, Weybridge, New Haw, Surrey Metabolite-Regulated Shutdown of Efflux Pumps is Critical for Mycobacterial Survival in Non-Permissive Growth Conditions, Obolbek Turapov, Simon J Waddell, Asel Sarybaeva, Bernard Burke, Sarah Glenn, Griselda Tudo, Gilles Labesse, Danielle I. Young, Michael Young Peter W. Andrew, Philip D. Butcher, Martin Cohen-Gonsaud, Galina V. Mukamolova, Department of Infection, Immunity and Inflammation, University of Leicester Redefining the mechanism of action of D-cycloserine in Mycobacterium tuberculosis, Gareth A. Prosser, Luiz Pedro Carvalho, National Institute for Medical Research, The Ridgeway, Mill Hill, London AZALEP A randomized controlled trial of azathioprine to treat leprosy nerve damage and reactions in India: main findings, Lockwood DNJ, Darlong J, Pichimani G, Royce KK, Sundar Rao, Annamma John, London School of Hygiene & Tropical Medicine, London A guide to killing your host cell, by Mycobacterium tuberculosis, Graham Stewart, Robert Francis, Rachel Butler, Tom Mendum, Shaza Felemban, University of Surrey Booking form All attendees MUST fill out the booking form regardless of whether they require refreshments. Booking forms from non-members will not be accepted without the name of a sponsoring member (who does not need to attend). Please complete and email the form with a payment confirmation to Tine Arnvig; <k.arnvig AT ucl.ac.uk> no later than Friday May 2nd. Member name Registration fee £5 Wine reception free Dinner including drinks ~£53 http://www.sarahwiener.de/ standard vegetarian other Visit to RKI (Y/N) Total Guest name Registration fee £10 Grand Total enclosed £ Please pay for your booking by Paypal at http://www.acidfastclub.co.uk if you can, otherwise please send a cheque with the booking form payable to the Acid Fast Club. To use Paypal, select options for dinner and drinks and this will be added to your PayPal cart, where you will be able to adjust the number required. The "continue shopping" option will allow you to return to the original page to select further items if required. When finished, select "View Cart" and you will be taken to PayPal to make final adjustments and payment