MICROCRYSTALLINE CELLULOSE
Microcrystalline Cellulose (MCC) is one of the most important and widely-used excipient. It functions as a diluent in formulations and an important component for oral dosage. MCC produced by Crest renders improved of production processes for direct compression and wet granulation, as well as for capsule formulations.
Our Microcrystalline Cellulose is available in different grades namely PH – 101, 102, 112, 200,
301 & 302 and other tailor made grades as required by the formulator.
MCC produced by Crest has high Compactability, thereby enabling to produce low forces.
Structural Formula of Microcrystalline Cellulose
CROSCARMELLOSE SODIUM
Croscarmellose Sodium is cross-linked Carboxymethylcellulose Sodium. Cross-linking is accomplished by removal of water molecule from two molecules of soluble
Carboxymethylcellulose Sodium.
The CCS made by Crest Cellulose aids in the disintegration and dissolution of pharmaceutical and dietary supplement tablets, capsules, and granules.
The CCS made by Crest Cellulose has the consistency in disintegration functionality. This results in high-quality super disintegrant. Its characteristic of faster disintegration makes it known as super disintegrant.
The cross-linked chemical structure of CCS creates an insoluble, hydrophilic, and highly absorbent excipient that results in exceptional swelling properties.

Structural formula of Croscarmellose sodium
SODIUM STARCH GLYCOLATE
Sodium starch glycolate is manufactured by carboxymethylation of starch. The carboxymethylation process increases the ability of the starch to absorb water, making it a rapid disintegrant.
Sodium starch glycolate is as a disintegrant in capsule and tablet formulations. It is recommended to use in tablets prepared by either direct-compression or wet-granulation processes.
Disintegration occurs by rapid uptake of water followed by rapid and enormous swelling.
The disintegrant efficiency of sodium starch glycolate is unimpaired in the presence of hydrophobic excipients, such as lubricants unlike many other disintegrants.
Sodium starch glycolate has also been investigated for use as a suspending vehicle.
Structural formula Sodium Starch Glycolate

MAGNESIUM STEARATE
Magnesium stearate consists of a magnesium salt joined by an ionic bond to two stearic acid molecules. Stearic acid, a saturated fat, is 18 carbons long and is common in our diet. This gives magnesium stearate a complex molecular formula of Mg (C18H35O2)2.
Magnesium stearate has lubricating properties, preventing ingredients from sticking to manufacturing equipment during the compression of chemical powders into solid tablets; magnesium stearate is the most commonly used lubricant for tablets.
Magnesium stearate is also used to bind sugar in hard candies like mints, and is a common ingredient in baby formulas.
Structural formula of Magnesium Stearate
DICALCIUM PHOSPHATE
Also known as calcium monohydrogen phosphate, is a dibasic calcium phosphate. It is usually found as the dihydrate, but it can be thermally converted to the anhydrous form. It is practically insoluble in water, with a solubility of 0.02 g per 100 mL at 25 °C. It is used as a tableting agent in pharmaceutical preparations.
Dicalcium phosphate , also known as dibasic calcium phosphate or calcium monohydrogen phosphate , is a type of calcium phosphate that is dibasic. It is usually found as the dihydrate, with the chemical formula of CaHPO
4
• 2H
2
O, but it can be thermally converted to the anhydrous form. It is practically insoluble in water, with a solubility of 0.02 g per 100 mL at
25 °C. It contains about 29.5 percent calcium in its anhydrous form.
Dicalcium phosphate may be formed by the of stoichiometric quantities (equimolar amounts) of calcium carbonate and phosphoric acid:

Dicalcium phosphate is mainly used as a dietary supplement in prepared breakfast cereals, dog treats, enriched flour, and noodle products. It is also used as a tableting agent in some pharmaceutical preparations, including some products meant to eliminate body odor. It is used in poultry feed. It is also used in some toothpastes as a tartar control agent.
Structural formula for Dicalcium Phosphate
PREGELATINIZED MAIZE STARCH
Pregelatinized maize starch is derived from starch by applying certain energies by which the starch gets gelatinized partially.
Partially Pregelatinized starch has only been partly cooked during manufacture and therefore contains some original starch grains. It is therefore suitable as a multifunctional excipient (filler
– binder – disintegrant) in both direct compression and wet granulation.
Pregelatinised maize starch has number of properties such as, a binder, disintegrant, lubricant and flow-aid. It is used in direct compression tablet formulations, wet granulations and capsule formulations.