DNA & Protein Synthesis Review NAME: ___________________________ DATE: ____________ Match the scientist(s) with their contribution. A) Erwin Chargaff B) Rosalind Franklin & Maurice Wilkins C) Watson & Crick D) Hershey & Chase ____ 1. Conducted an experiment that determined that DNA is the genetic material passed on to offspring ____ 2. Discovered the base pairing rules and the ratios of base pairs in different species ____ 3. Considered to be the Fathers of DNA ____ 4. Took the first picture of DNA using the process of X-ray crystallization 5. What is an example of a molecule produced by this type of process? ______________ 6. Number 1 in the diagram above is a representation of a/an ____________ 7. Number 2 in the diagram above is a representation of a/an ____________ 8. Number 4 in the diagram above is a representation of a/an ____________ 10. Which type(s) of RNA take(s) the DNA code to the ribosome? _________ 11. Is it necessary for a molecule of mRNA to attach to a ribosome for protein production?_______________ 13. The parts of DNA that provide the code for proteins are the _______________________. 14. A DNA nucleotide may be made up of a phosphate group, along with _________________ and a ________________ _______. 15. The backbone of a DNA molecule is made of which two components?_______________ & ___________ 16. A change in the genetic code is called a _______________. 17. When mRNA is made, thymine is replaced with what base? __________ 19. Two researchers, Maurice Wilkins and Rosalind Franklin, used X-ray crystallography to make pictures of DNA such as the one below. The picture shows an X-ray diffraction pattern of DNA. This type of image helps show that DNA’s shape is a ____________ ________. 20. Which type(s) of RNA make(s) up the ribosomes? _________ 22. Which type of mutation does the most damage to an organism? _________________ 23. The “code word” or codon for an amino acid is made of how many bases? _________ 25. Amino acid molecules, bound together into chains, form: _____________ 26. The process by which a DNA molecule is copied is called ________________. 27. DNA does NOT contain the nitrogen base ___________. 28. When transcription has been completed, what new molecule has been made? _________ 29. The DNA of all living things contains the same four nitrogen bases. True or False? ______________ 30. Put the following molecules in the correct sequence to describe the production of a protein in a cell. tRNA, mRNA, protein, DNA _______________ _______________ _______________ _______________ 31. The process by which proteins are built is called: ________________ 32. Amino acids are carried to ribosomes after they are attached to: ___________ 33. Anticodons are a part of molecules of: _________ 34. Mustard gas removes guanine from DNA. This can cause serious multiple deformities because guanine is one of the ________________ __________ of DNA. 35. Match the nitrogenous bases as found in DNA. ____________ goes with _____________ ____________ goes with _____________ 36. Match the nitrogenous bases as found in RNA. ____________ goes with _____________ ____________ goes with _____________ 37. What is a frameshift mutation? 38. What is a point mutation? What are the 3 types of point mutations? 39. What are the 4 types of chromosomal mutations? 40. Replicate the complementary DNA strand for the following sequences: TATACCGATGCA CCGAATGGC CGCGAATTCGCA _______________ ____________ ________________ 41. Transcribe the mRNA strand for the following sequences of DNA: TATACCGATGCA CCGAATGGC CGCGAATTCGCA _______________ ____________ ________________ 42. Translate the mRNA into tRNA for the following sequences: AUAUGGCUACGU GGCUUACCG GCGCUUAAGCGU _______________ ____________ ________________ 43. GCATCCGAT ____________ GCATCCGAT ____________ CGUAGGCUA ____________ Which amino acid goes with each codon? UAU = _______ UUG = _______ CCG = _______ AAA = _______ CGC = _______ UUU = _______ ACC = _______ GGG = _______ AAU = _______ CCC = _______ GAA = _______ CAA = _______ CAU = _______ UAG = _______ GGC = _______ GAG = _______ GCA = _______ ACG = _______ 44. In your own words, explain the process of DNA replication. 45. Explain transcription. 46. Explain translation.