Ronald R. Marquardt
Professor
Department of Animal Science
Curriculum vitae
Ronald R. Marquardt, Ph.D., Professor Emeritus, Nutritional of Biochemistry, Department
of Animal Science, University of Manitoba, Winnipeg, Manitoba R3T 2N2
Mail Address: 878 Kilkenny Drive, Winnipeg, Manitoba R3T 4G3
Telephone: 204-269-1379
E-mail: ronald.r.marquardt@gmail.com
Follow these links to different sections within this CV
Education
Experience and Positions Held
Teaching
Membership in Organizations, Societies, etc.
University Committees and Administrative Services
National and International Commitees
Community Service
Awards and Patents
Research Associates and Graduate Students
Overview of Research and Research Collaborators
National and International Lecture Invitations
Publications
Refereed Journals
Proceedings
Books
Book Chapters and Reviews
Abstracts
I. EDUCATION:
Name of Institution
University of Saskatchewan
University of Alberta
Wsahington State University
Location
Saskatoon, Sask.
Edmonton, Alta.
Pullman, Wash.
Degree
B.S.A.
M.Sc.
Ph.D.
Date
1958
1961
1965
II. EXPERIENCE AND POSITIONS HELD:
1. Professor, Department of Animal Science, University of Manitoba, Winnipeg - 1976 to
present. Research involving:
a) Livestock mycotoxicosis from stored cereal grains: Structure-function and mode of
action of ochratoxin A (current).
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b) Purification, isolation and mode of action of vicine, convicine and their metabolites
from Vicia faba (faba beans) (current).
c) Enhancement of the nutritive value of cereal grains through the use of enzymes:
Role of water-soluble arabinoxylans (current).
2. Professor Emeritus, Department of Animal Science, University of Manitoba, Winnipeg,
2000 - present. Activities included the following:
a) Completed supervision of two PhD students
b) Served as Committee member for several PhD students
c) Co-author on 27 peer-reviewed publications and two book chapters or reviews.
d) Director of Research and Development of two local biotechnology companies, Zyme
Fast Inc. and All Natural Nutritional Products.
e) Successful applicant on more than five national grants involving
1) Production of therapeutic antibodies in the egg of laying hens
hyperimmunized with recombinately produced virulence factors;
2) Evaluation of Zyme Fast’s recombinately produced epidermial growth factor in
the control of mastitis in lactating cows and as a growth promotant in pigs;
3) Development of a lateral flow immunological assay for the detection of
Salmonella enteritidis and E. coli F4;
4) Development of a rapid HPLC method for analysis of resveratrol, quercetin
and emodin in nutraceutical supplements;
5) Identification of bioactive compounds in Red-Osier Dogwood.
3. Associate Professor (1970-1976) and Assistant Professor (1967-1970), Department of
Animal Science, University of Manitoba, Winnipeg. Research as for 1.
4. Postdoctoral Research Associate and Lecturer, Department of Chemistry, Washington
State University, Pullman, Washington - 1965 to February 1967.
5. Research Assistant, Department of Animal Sciences (Dairy), Washington State University,
Pullman, Washington - 1961 - 1965. Ph.D. research.
6. Research Assistant, Department of Animal Sciences, University of Alberta, Edmonton,
Alberta. M.Sc. research. 1959-1961.
III. TEACHING:
1. Principles of Nutritional Toxicology 35.311
- Given in fall of each year
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2. Advanced Animal Metabolism 35.732
- Given in fall of each year
3. Protein Metabolism 35.735
- Given in alternate years in second term
IV. MEMBERSHIP IN ORGANIZATIONS, SOCIETIES, ETC.:
1. American Society of Microbiology
2. Society of Sigma Xi
3. Canadian Biochemical Society
4. American Chemical Society
5. Canadian Society of Animal Science
6. Nutrition Society of Canada
7. Association for the Advancement of Science
8. American Institute of Nutrition
9. American Society of Animal Science
10. Society of Toxicology of Canada
V. (A) UNIVERSITY COMMITTEES AND ADMINISTRATIVE SERVICES (1985 current):
1. Chairman of Pesticide Research Laboratory Committee (former)
2. Editor, Animal Science section of the 20th to 29th editions of the Agriculture Progress
Reports
3. Chairman of Awards Committee Sigma Xi (former)
4. Member of Senate, University of Manitoba (former)
5. Member of Senate Committee on Administrative Benefits (former)
6. Member of Senate Committee on Student Appeals (former)
7. Member of University Research Committee of Senate (1989-1992)
8. Member of Faculty Research Committee (reappointed)
9. Member of University of Manitoba Research Committee (reappointed)
10. Member of Foods and Nutritional Science Interdepartmental Ph.D. Committee
11. Member of Animal Science Department Graduate Student Selection Committee
12. Member of University ad hoc Review Committee for Small Grants Program (1992)
13. Member of Selection Committee for Associate Vice President (Research) (1992)
14. Member of Manitoba Research Council (EITC)/ University of Manitoba Agri-Food
Biotechnology Program Committee
(B) NATIONAL AND INTERNATIONAL COMMITTEES (1985 - current):
1. Expert Evaluator for Food Quality and Safety, Integrated Food Chain Panel, European
Commission, Brussels (June and July 2000)
2. Member, IRTAS (Institut de Recerca & Tecnologia Agroalimentaries), Scientific Advisory
Committee, Barcelona, Spain (2001–)
3. Member, Committee on Animal Nutrition, National Research Council, National Academy of
Sciences (US) (1990-1993) (Canadian Delegate)
4. Editor, Canadian Journal of Animal Science (1990-1993)
5. Member, Scientific Journals Committee; Agricultural Institute of Canada (1990-1993)
6. Member of Editorial Policy Board, Canadian Journals of Agricultural Sciences (1989-1993)
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7. Member of
(1991-1992)
8. Member of
9. Member of
10. Associate
NSERC Strategic Grants Selection Panel on Food, Agriculture and Aquaculture
NSERC Grant Selection Committee for Animal Biology, (1985-1988)
International Union of Nutritional Sciences Executive Committee (1985-1993)
Editor Canadian Journal of Animal Science (1988-91)
VI. COMMUNITY SERVICE:
1.
2.
3.
4.
5.
Coach of Fort Richmond Community Club Hockey Team (former)
Coach of Fort Richmond Community Club Soccer Team (former)
Coordinator of Aggie Row Curling Club (former)
Coach of Fort Richmond Community Club Ringette Team (former)
Assistant Coach and Treasurer of Manitoba Marlin's Swim Club (former)
VII. AWARDS Awards:
1. Canadian Society of Animal Science Award of Merit. 1998. This is the highest award of
the Society.
2. Jiangsu Province Friendship Award for excellence in cooperative work between Nanjing
Agricultural University and University of Manitoba, Dec., 1997.
3. Shur-gain Award for Excellence in Nutrition and Meat Sciences. This is the highest award
that the Canadian Society of Animal Science bestows in the field of Nutrition and Meat
Science. There is one award per year, July 1992.
4. Sigma Xi (Manitoba Chapter) Senior Scientist Award. Awarded annually to an individual
who has made an outstanding contribution in the field of science in Manitoba, April 1992.
5. University of Manitoba Graduate Students Association Award for Excellence in Graduate
Teaching, 1990-1991. Usually one award per year. Nominations are made by the Graduate
Students.
6. Faculty of Agriculture Merit Award
7. Appointed Professor in May 1994 in the Laboratory of Animal Physiology and
Biochemistry, Nanjing Agricultural University, Nanjing P.R. China. This laboratory has been
designated as one of the key National Laboratories in China.
VIII. RESEARCH ASSOCIATES AND GRADUATE STUDENTS: (1980 - current)
1. Research Associates and Visiting Scientists:
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
A.T. Ward, Canada
A.A. Frohlich, Poland
I. Hegazy, Egypt
M.S.S. Arbid, Egypt
S. Yannai, Israel
O. Sreemannarayana, India
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Dr. J. Pawlik, Poland
Dr. B. Rotter, Canada
Dr. M.S. Madhyastha, India
Ms. M D. Jimenez, Spain
Ms. C. Barbano, Spain
Dr. M. Musquiz, Spain
Dr. A. Brenes, Spain
Dr. R.G. Rotter, Canada
Dr. J. Brufau, Spain
Dr. D. Boros, Poland
Ms. Suzhen Li, China
Ms. Liuqiung Lu, China
Dr. Z. Gan, China
Dr. D. Kierek-Jaszczuk, Canada
Dr. Han Zhengkang, China
Dr. N. Canibe, Spain
Mr. Z. Zhang, China
Dr. M. Höhler, Germany
Dr. Wang Guojie, China
Dr. Borja Vilá, Spain
Dr. Jung-Woo Kim, Korea
Mr. Ge Pingbin, China
Dr. L-Z. Jin, China
Mr. Fang Lin, China
Ms. Seung-Yon Koh, Korea
Mr. Suk-Hyeon Cho, Korea
2. Ph.D. Students:
Mr. A.T. Ward
Mr. D.S. Muduuli
Mr. A. Fengler
Mr. R.G. Rotter
Ms. Lu Ping
Ms. K.H. Ominski
Mr. A. Jansman
Mr. J. Clarke
Mr. Hao Xiao
Ms. Suzhen Li
Mr. Ziad Jaradat
Mr. Z. Zhang
Mr. Augustine Owusu-Asiedu
Mr. Suk-Hyeon Cho
3. M.Sc. Students:
Mr. Steven Cole
Ms. Q. Zhang
10 others
IX. OVERVIEW OF RESEARCH AND RESEARCH COLLABORATORS (1991 - current)
a) Overview of some of the research carried out:
1. Passive immunization of animals with egg-yolk antibodies: Diarrheal diseases, especially
those caused by Escherichia coli and Salmonella species are responsible for serious health
problems in humans and in animals especially weanling pigs. There is a urgent need to find
alternative means to control intestinal pathogens as many are resistant to antibiotic.
Research in our laboratory has focussed on the development of procedures to protect young
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pigs against E. coli induced diarrhea (8, 20). The results have demonstrated that chicken
egg-yolk antibodies against E. coli fimbriae when administered orally are able to completely
neutralize E. coli induced pathogenesis (see XI reference 8). The production of idiotype and
anti-idiotype monoclonal and polyclonal antibodies in chickens, rabbits and mice have
provided powerful new tools for the isolation and characterization of intestinal receptors for
E. coli (see references 1, 2, 4, 9 and recent Ph.D. thesis by Z. Jaradat). Recently we have
demonstrated that a plasmid which comprises genes coding for fimbrial submit antigens of
enterotoxigenic E. coli strains can be used as a DNA vaccine to produce antibodies in
chicken eggs. This new procedure offers many advantages over conventional procedures
and will probably provide the basis of a highly effective means of producing inexpensive
antibodies in egg-yolks for the passive immunization of humans and animals against enteric
diseases. A patent has been filed on this invention (see Patents, section VII). A local
Winnipeg based start up company will produce and market vaccines, diagnostic assays and
therapeutic antibodies against the different intestinal pathogens. The genetic vaccine patent
will provide a significant competitive advantage for this company.
2. Development of assays for high throughput screenings: Recent evidence suggests that
proteases play an important role in the growth and proliferation of pathogenic bacteria and
enhancing pathogenesis of severe diseases. Protease, as a virulence factor, has stimulated
the search for potent disease curing drugs that can inhibit them, an example of which is HIV
protease inhibitor. During the screening for promising drug candidates hundred of
thousands of compounds need to be assayed in order to identify a few leads that are
biologically active. A new type of solid-phase assay for protease, protease inhibitors and
several other types of enzymes and their inhibitors was developed in our laboratory that is
sensitive, accurate, simple, rapid and adaptable. It is inexpensive to use and can be readily
automated. A total of 4 papers (see references 10, 11, 12, 19, section XI) have been
published on the subject. We have been recently invited to be guest editors for review
papers on our and related technologies for "Combinational Chemistry and High Throughput
Screening" one of the most important journals in the field. We have also filed two patents
on the procedure (1 and 2 section VII). Currently, we are in the final stages of negotiations
with an American based venture capital company to develop and market related products.
The technology developed in both of the above examples were a spin-off of research carried
out on mycotoxins which has been extensively supported by NSERC operating and strategic
grants.
3. Ochratoxin, a mycotoxin: Ochratoxin A, (OA) occurrence in food is widespread especially
in Canadian swine products, feeds and in human blood (references 7, 40, 117). It has been
shown to be a powerful carcinogen, hepatotoxin and nephotoxin, often causing an
irreversible and fatal kidney disease. Research on OA in our laboratory has focussed on the
isolation and characterization of the different ochratoxins, its mode of action at the cell level
and its structure-function interrelationships (see references 3, 5-7, 13, 14, 16-18, 22, 23,
25, 29-31, 33, 34, 37, 39-42, 44, 46, 48-51, 53-61, etc.). Research of particular
importance was the discovery of a new and highly toxic form of OA, the lactone opened
form (reference 42); the demonstration, using electron paramagnetic resonance
spectrometry in a model in vivo system, that OA stimulated the production of hydroxyl
radicals, one of the most reactive chemical species known (references 29, 31, 37, 39); and
the identification of the intracellular protein targets of OA (5). In this latter research OA
binding proteins were affinity purified, the N-terminal sequence of 24 residues were
determined and shown to be 100% identical to aldehyde dehydrogenase class 2 (ALDH2, EC
1.2.1.3). This is the first study that has implicated this enzyme. Many of the toxic effects of
OA may be explained on the basis that an inhibition of the aldehydic dehydrogenases will
result in the accumulation of highly reactive aldehydes especially acetylaldehyde. These
compounds would have a particularly serious synergistic effect for individuals that consume
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alcohol and are expose to ochratoxin, as many Canadians are. We believe that we have
made fundamental new contributions on the pathology of ochratoxicosis.
b) Collaborators: Animal Science, Univ. of Manitoba: Dr. A.A. Frohlich - Nutritional
Biochemistry; Dr. S. Baidoo - Swine Nutrition; Dr. W. Guenter - Poultry Nutrition; Dr. J.R.
Ingalls - Ruminant Nutrition; Dr. G.H. Crow -Statistics. Univ. of Manitoba: Dr. T.G. Vitti,
Faculty of Pharmacy - Pharmacokinetics; Dr. J. Zawistowski, Food Science - Immunology;
Dr. J. Peeling, Medical School - Nuclear Magnetic Resonance Spectrometry; Drs. Y. Ling and
A. McIntosh, Faculty of Pharmacy - Organic Synthesis and Electron Spin Resonance
Spectrometry; Dr. G. Blank, Food Science - Mycology of ochratoxin A. Manitoba Institutions:
Drs. D. Abramson and J.T. Mills, Agriculture Canada, Winnipeg - Analytical Chemistry and
Mycology; Mr. R. Clear, Grain Res. Lab. Can. Grain Commission - Mycology; Drs. J. Borsa
and J.C. Szekely, AECL, Pinawa, MB - Radiation Chemistry and Tissue Culture; Dr. F. Juck Veterinary Pathology and Dr. G. Nayar - Veterinary Microbiology, Manitoba Agriculture,
Winnipeg. National and International Institutions and Universities: Dr. B. Kemppainen, Univ.
of Auburn - AL-Cell Culture; Dr. B. Tuchweber, Department of Nutrition, Medical School,
University of Montreal - Detoxification of ochratoxin; Dr. Z-K Han, Nanjing Agricultural
University - Mode of action of enzymes; Dr. D. Höhler, Kiel University, Germany Detoxification of ochratoxin A; Dr. H. van Egmond, Head, National Institute Public Health,
The Netherlands - Carcinogenic studies on ochratoxin A; Drs. Gang Li, Faculty of Medicine,
University of British Columbia, Dr. Hao Xiao, Immune Chem Pharmaceuticals Inc,
Vancouver, BC and Dr. M. Arbid, National Research Centre, Cairo, Egypt - Mechanism of
action of ochratoxin A; and Dr. J-W Kim, Dankook University, Korea - Studies on therapeutic
antibodies.
c) Nature of Collaborations: Twenty-one of these researchers have been coauthors on 50
of the 56 peer reviewed publications listed above. The research listed in this form is
primarily the results of initiatives by the applicant. This includes the preparation of research
grant proposals, the assembly of the team of researchers and collaborators, the overall
direction of research and the responsibility for the publication of papers. In general the
papers in which I am second or third author represents research carried out in the
applicant's laboratory by Ph.D. students, PDF, Research Associates and Visiting Scientists.
The research is multidisciplinary in nature and requires input from other experts. I have
interacted with collaborators in a broad range of disciplines such as physiology, chemistry,
biochemistry, mycology, pathology, microbiology and nutrition. This has greatly enriched
our programme of research. For example, the synthesis of several of our ochratoxin A
analogs, required input from organic and analytical chemists (NMR and MS, see
collaborators and papers by Xiao et al). Likewise, the availability of a pharmacokinetist and
a veterinary pathologist has greatly assisted in the design of experiments and the
interpretation of results on the disposition and the pathological effects of ochratoxin A.
d) Journal selections: Journals are selected on the basis of relevance to the subject and
to a lessor degree on the basis of their impact as ranked by SCI Journal Citation Reports.
Many of our publications are in journals that have an impact factor of greater than 1.5, a
value that is in the upper 20 percentile of all Journals. Our research has been published in a
wide range of national (6) and international (50) journals covering different disciplines
including chemistry - biochemistry (8), nutrition (14) toxicology-mycology (12), pathology
(4), microbiology (7) and immunoassays (11).
e) Impact of patents and evidence for technological transfer: The development of
solid-state and bio-assays for biologically active substances (patents 1 and 5) will facilitate
the production of assays that utilize innovative high throughput technologies that are
simple, rapid, sensitive, accurate and inexpensive. This technology is being commercialized
by a local company in association with an American Biotechnology Company. Potential sales
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are large since the assays can be utilized for the assay of enzymes involved in the
hydrolysis of polymeric substance such as carbohydrates, proteins and DNA and
corresponding inhibitors of these enzymes. This is particularly important for protease
inhibitors which are being intensely investigated. Two bioassays also have been developed
which are capable of detecting low concentrations of trichothecences or non-trichothecene
mycotoxins and most of the common antibiotics. Two companies are interested in
commercialization of these assays. A procedure has also been developed for the preparation
of monospecific polyclonal antibodies using ligand affinity chromatography. A new
Vancouver based company, ImmuneChem Pharmaceuticals, Inc. markets affinity purified
antibodies using technology developed in our laboratory.
X. NATIONAL AND INTERNATIONAL LECTURE INVITATION (1985 - Current)
= 35
XI. PUBLICATIONS:
Refereed Journals (Total = 247)
1. Omar, J.M., H. Yang, S. Li, R.R. Marquardt, P.J. H. Jones, 2014. Development of an
improved reverse-phase high-performance liquid chromatography method for the
simultaneous analysis of tran-/cis- resveratrol, quercetin, and emodin in commercial
resveratrol supplements. J. Agric. Food Chem. 62(25):5812-5817.
2. Blank, R., J.-P. Rolfs, K.-H. Sudekum, A.A. Frohlich, R.R. Marquardt, S. Wolffram,
2014. Effect of roughage: concentrate ratio in the diet on systemic availability and
excretion of ochratoxin A in sheep. J. Animal Feed Sci. 13(Suppl. 1):673-676.
3. Biswas, D., P. Herrera, L. Fang, R.R. Marquardt, S.C. Ricke, 2010. Cross-reactivity of
aniti-Salmonella egg-yolk antibodies to Salmonella serovars. J. Environ. Sci. & Health
Part B. 45: 1-6.
4. Jaradat, Z. W., R.R. Marquardt, A.A. Frohlich, Q.O. Ababneh, 2010. Chicken antiidiotypic antibodies as an alternative to the antimicrobial treatment for the control of
Escherichia coli K 88 in domestic animals. Jordan J. Agric. Sci. 6:41-57.
5. Jaradat, Z.W., B. Vila and R.R. Marquardt. 2006. Adverse effects of T-2 toxin on
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chicken lymphocytes blastogenesis and its protection with vitamin E. Toxicology 225
(2-2): 90-96
Cho, S-H, P.C. Loewen and R.R. Marquardt. 2006. Enhanced antibody response in
mice injected with a DNA vaccine that co-expresses both cytokine and
Escherichia coli F4 fimbrial antigen. Infect. Immun. 83: 1973-1978.
Cho S-H, P.C. Loewen and R.R. Marquardt. 2004. A plasmid DNA encoding chicken
interleukin-6 and Escherichia coli K88 faeG stimulates the production of K88 fimbriae
antibodies in chickens. Poultry Sci.83:1073-1978.
Blank, R., J-P. Rolfs, K-H. Südekum, A. Fröhlich, R.R. Marquardt and S. Wolffram.
2003. Effects of chronic ingestion of ochratoxin A on blood levels and excretion of the
mycotoxin in sheep. J. Agric. Food Chem. 51:6899-6905.
Brenes, A., B.A. Slominski, R.R. Marquardt, W. Guenter and A. Viveros. 2003. Effect
of enzyme addition on the digestibility of cell wall polysaccharides and
oligosacchorides from whole, dehulled and ethanol extracted fractions of white lupins
in chickens. Poultry Sci. 82:1716-1725.
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10. Owusu-Asiedu, A., C.M. Nyachoti, and R.R. Marquardt. 2003. Response of early-
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weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed dietsRR
containing spray-dried porcine or pea protein isolate plus egg-yolk antibody, zinc
oxide, furmaric acid or antibiotic. J. Animal Sci. 81:1790-1798.
Owusu-Asiedu, A., C.M. Nyachoti, S.K. Baidoo and R.R. Marquardt. 2003. Response
of early weaned pigs to enterotoxigenic Escherichia coli (K88) challenge when fed
diets containing spray-dried porcine plasma or pea protein isolate plus egg-yolk
antibody. J. Animal Sci. 81:1781-1789..
Boros, D., R.R. Marquardt, W. Guenter, J. Brafau. 2002. Chick adaptation to diets
based on milling fractions of rye varying in arabinoxylans content. Anim. Feed Sci.
Tech. 101:135-149.
Brenes, A. R.R. Marquardt, W. Guenter and A. Viveros. 2002. Effect of enzyme
addition on the performance and gastrointestinal tract size of chicks fed lupin seed
and their fraction. Poultry Science 81:670-678.
Owusu-Asiedu, A., S.K. Baidoo, C.M. Nyachoti, and R.R. Marquardt. 2002. Response
of early-weaned pigs to spray-dried or animal plasma-based diets supplemented with
egg-yolk antibodies against enteratoxigenic Escherichia coli. J. Animal Sci. 80:28952903.
Villa B., Z.W. Jaradat, R.R. Marquardt and A. A. Frohlich. 2002. Effect of T-2 toxin
on in vivo lipid peroxidation and vitamin E status of mice. Food Chem. Toxicity
40:479-486.
Jaradat, Z.W. and R.R. Marquardt. 2001. Identification of E. coli K88 receptor in
porcine intestinal mucus using antiidiotypic antibodies. Food Agric. Immunol.
13:241-253.
Zhang, Z., R.R.Marquardt, W. Guenter and G.H. Crow. 2001. Development of a
multi- purpose feed enzyme analyzer to estimate and evaluate the profitability of
using feed enzyme preparations for poultry. Poultry Sci. 80:1562-1571.
Dortant, P.M., G.W.M. Peters-Volleberg, H. van Loveren, R.R. Marquardt and G.J.A.
Speijers. 2001. Age-related differences in the toxicity of ochratoxin A in female rats.
Food Chem. Toxicol. 39:55-65.
Jin, L.Z., R.R. Marquardt and X. Zhao. 2000. A Strain of Enterococcus faecium
(18C23)inhibits adhesion of enterotoxigenic Escherichia coli K88 to porcine small
intestine mucus. Appl. Environ. Microbiol. 66:4100-4204.
Jaradat, Z.W. and R.R. Marquardt. 2000. Studies on the stability of chicken IgY in
different sugars, complex carbohydrates and food materials. Food Agric. Immunol.
12:263-272.
Fang, L., Z. Gan and R.R. Marquardt. 2000. Isolation, affinity purification and
identification of piglet small intestine mucus receptor for enterotoxigenic Escherichia
coli K88ac+ fimbriae. Infect. Immuno. 68:564-569.
Jin, L.Z., R.R. Marquardt, S.K. Baidoo and A.A. Frohlich. 2000. Characterization and
purification of porcine and intestinal mucus receptor for Escherichia coli K88ac
fimbrial adhesion. FEBS Immunol. Med. Microb. 27:17-22.
Zhang, Z., R.R. Marquardt, W. Guenter, J. Cheng and Z. Han. 2000. Prediction of
effect of enzymes on chick performance when added to cereal-based diets: Use of a
modified log-linear model. Poultry Sci. 79:1757-1766.
Zhang, Z., R.R. Marquardt and W. Guenter. 2000. Evaluating the efficacy of enzyme
preparations and predicting the performance of leghorn chicks fed rye-based diets
using a dietary viscosity assay. Poultry Sci 75:1158-1167.
Jin, L.Z., R.R. Marquardt and S.K. Baidoo. 2000. Inhibition of enterotoxigenic
Escherichia coli K88, K99 and 987P by the Lactobacillus isolates from porcine
intestines. J. Sci. Food Agric. 80:619-624.
Xiao, H. R.R. Marquardt, G. Li and A.A. Frohlich. 2000. Isolation, purification and
identification of intracellular protein-targets of ochratoxin A: mitochondrial aldehyde
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dehydrogenase class 2 is a high affinity ochratoxin A binding protein. J. Sci. Food
Agric. 79:2099-2104.
Li, S., Marquardt, R.R. and Frohlich, A.A. 2000. Identification of ochratoxins and
some their metabolites in bile and urine of rats. Food. Chem. Toxicol. 141-142.
Kerkadi, A., C. Barriault, R.R. Marquardt, A.A. Frohlich, I.M. Yousef, X.X. Zha and B.
Tuchweber. 1999. Cholestyramine protection against ochratoxin A (OTA) toxicity:
role of OTA sorption by the resin and bile acid enterohepatic circulation. J. Food
Protection. 62:1461-1465.
Marquardt, R.R., L.Z. Jin, J-W. Kim, L. Fang, A.A. Frohlich and S.K. Baidoo. 1999.
Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia
coli K88+ infection in neonatal and early weaned piglets. FEBS Immunol. Med.
Microbiol.23:283-288.
Kim, J.W., L.Z. Jin, S-H Cho, R.R. Marquardt, A.A. Frohlich and S.K. Baidoo. 1999.
Use of chicken egg-yolk antibodies against K88+ fimbrial antigen for quantitative
analysis of enterotoxigenic Escherichia coli (ETEC) K88+ by a sandwich ELISA. J. Sci.
Food Agric. 79:1513-1518.
Gan, Z., R.R. Marquardt and H. Xiao. 1999. Protease and protease inhibitor assays
using biotinylated casein coated on a solid-phase. Anal. Biochem. 268:151-156.
Gan, Z. and R.R. Marquardt. 1999. Colorimetric competitive inhibition method for the
quantitation of avidin, streptavidin and biotin. J. Biochem. Biophys. Methods 39:1-6.
Wang, G., R.R. Marquardt, H. Xiao and Z. Zhang. 1999. Development of a 96-well
enzyme-lined solid-phase assay for ß-glucanase and xylanase. J. Agric. Food Chem.
47:1262-1267.
Abramson, D., R. Hulasare, N.D.G. White, D.S. Jayas and R.R. Marquardt. 1999.
Mycotoxin formation in hulless barley during granary storage at 15 and 19%
moisture content. J. Stored Prod. Res. 35:297-305.
Höhler, D., K-H Südekum, S. Wolffram, A.A. Frohlich and R.R. Marquardt. 1999.
Metabolism and excretion of ochratoxin A fed to sheep. J. Anim. Sci. 77:1217-1223.
Boros, D., R.R. Marquardt and W. Guenter. 1998. Site of exoenzyme action in
gastrointestinal tract of broiler chicks. Can. J. Anim. Sci. 78:599-602.
Abramson, D., Z. Gan, R.M. Clear, J. Gilbert and R.R. Marquardt. 1998. Relationship
among deoxynivalenol, ergosterol and Fusarium exoantigens in Canadian hard and
soft wheat. Inter. J. Food Microbiol. 45:217-224.
Li, S., R.R. Marquardt and A.A. Frohlich. 1998. Confirmation of ochratoxins in
biological tissues by conversion into methyl esters in acidified methanol. J. Agric. and
Food Chem. 46:4307-4312.
Blank, G., U. Nwoko, A. Frohlich, R.R. Marquardt. 1998. Ochratoxin A production in
relation to the growth morphology of Aspergillus alutaceus. Lebensm. - Wiss. U.
Technol. 31:210-214.
Gan, Z. and R.R. Marquardt. 1998. Biotinylated enzyme inhibitorsorbant assay: A
specific method for quantitating enzyme and its inhibitors. Anal. Biochem. 256:6973.
Jin, L.Z., S.K. Baidoo, R.R. Marquardt and A.A. Frohlich. 1998. In vitro inhibition of
adhesion of enterotoxigenic Escherichia coli K88 to piglet mucus by egg-yolk
antibodies. FEBS Immunol. Med. Microb. 21:313-321.
Zhang, Z., R.R. Marquardt, W. Guenter and Z. Han. 1998. Effect of different enzyme
preparations supplemented in a rye-based diet on the performance of young broilers
and the viscosity of digesta and cloacal excreta. Chinese J. Anim. Sci. 34(1): 3-6.
Hoehler, D. R.R. Marquardt, A.R. McIntosh and M.S. Madhyastha. 1998. Free radicalmediated lipid peroxidation induced by T-2 toxin in yeast (Kluyveromyces
marxianus) J. Nutr. Biochem. 9:370-379.
10
44. Hoehler, D., A.A. Frohlich, R.R. Marquardt, and H. Stelsovsky. 1998. Extraction of a45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
58.
59.
60.
61.
tocopherol from serum prior to reversed-phase liquid chromatography J. Agric. Food
Chem. 46:973-978.
Brufau, J. Boros and R.R. Marquardt. 1998. Influence of growing season, tannin
content and autoclave treatment on the nutritive value of near-isogenic lines of faba
beans (Vicia faba L) when fed to Leghorn chicks. Br. Poultry Sci. 39:97-105.
Kerkadi, A., C. Berriault, B. Tuchweber, A. Frohlich, R.R. Marquardt, G. Bouchard and
I.M. Yousef. 1998. Dietary cholestyramine reduces ochratoxin A-induced
nephrotoxicity in the rat by decreasing plasma levels, and enhancing fecal excretion
of the toxin. J. Toxicol. Environ. Health; Part A, 53:231-250.
Gan, Z., R.R. Marquardt, D. Abramson and R.M. Clear. 1997. The characterization of
chicken antibodies raised against Fusarium spp. by ELISA and immunoblotting. Inter.
J. Food Microbiol. 38:191-200.
Pan, C.F., F.A. Igbason, W. Guenter and R.R. Marquardt. 1997. The effects of
enzyme and inorganic phosphorus supplementation in wheat- and rye-based diets on
laying hen performance, energy and phosphoric availability. Poultry Sci. 77:83-99.
Jaradat, Z. and R.R. Marquardt. 1997. L arginine as a therapeutic approach for the
vertotoxigenic Escherichia coli induced hemolytic uremic syndrome and thrombotic
thrombocytopenic purpura. Med. Hypotheses 49:277-280.
Höhler, D., R.R. Marquardt and A.A. Frohlich. 1997. Induction of lipid peroxidation by
iron nitrilotriacetate and ochratoxin A in vivo and in vitro. Can. J. Anim. Sci. 77:287292.
Li, S., R.R. Marquardt, A.A. Frohlich, T.G. Vitti and G. Crow. 1997. Pharmacokinetics
of ochratoxin A and its metabolites in rats. Toxicol. Appl. Pharmacol. 145:82-90.
Hoehler, D. R.R. Marquardt, A.R. McIntosh and G.M. Hatch. 1997. Induction of free
radicals in hepatocytes, mitochondria and microsomes of rats by ochratoxin A and its
analogs. Biochem. Biophys. Acta 1357:225-233.
Kierek-Jaszczuk, D. R.R. Marquardt and D. Abramson. 1997. Use of heterologous
solid-phase antigen in an indirect competitive antibody-capture enzyme-linked
immunosorbent assay for T-2 mycotoxin, J. Food Prot. 60:321-327.
Abramson, D., T.J. Mills, R.R. Marquardt and A.A. Frohlich. 1997. Mycotoxins in
suspected samples of animal feed from Western Canada, 1982-1994. Can. J. Vet.
Res. 61:49-52.
Frohlich, A.A., R.R. Marquardt and J.R. Clarke. 1997. Enzymatic and immunological
based approach for the quantification and confirmation of ochratoxin A in swine
kidneys. J. Food Prot. 60:172-176.
Wang, G.J., R.R. Marquardt, W. Guenter, Z. Zhang and Z. Han. 1997. Effects of
enzyme supplementation and irradiation of rice bran on the performance of growing
Leghorn and broiler chicks. Anim. Feed Sci. Tech. 66:47-61.
Gan, Z. and R.R. Marquardt. 1996. Analysis of exoantigens from Fusarium by SDSPAGE and immunoblotting. Acta Microbiol. Sinica 36:208-212.
Hoehler, D., R.R. Marquardt, A.R. McIntosh and H. Xiao. 1996. Free radical
generation as induced by ochratoxin A and its analogs in bacteria (Bacillus brevis). J.
Biol. Chem. 271:27388-27394.
Park, I.K. and R.R. Marquardt. 1996. Effect of niacin deficiency on the thermal
stability of NAD- and NADP- dependent dehydrogenases in liver and pectoral muscle
of Japanese quail. Inter. J. Biochem. Cell Biol. 28:1169-1177.
Hoehler, D. and R.R. Marquardt. 1996. Influence of vitamins E and C on the toxic
effects of ochratoxin A and T-2 toxin in chicks. Poultry Sci. 75:1508-1515.
Ominski, K.H., A.A. Frohlich, R.R. Marquardt, G.H. Crow and D. Abramson. 1996.
The incidence and distribution of ochratoxin A in western Canadian swine. Food
Addit. Contam. 13:185-198.
11
62. Xiao, H., R.R. Marquardt, D. Abramson and A.A. Frohlich. 1996. Metabolites of
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
ochratoxin A in rat urine and in a culture of Aspergillus ochraceus. Appl. Environ.
Micro. 62:648-655.
Xiao, H., M.S. Madhyastha, R.R. Marquardt, S. Li, J.K. Vodela and W. Kemppainen.
1996. Toxicity of ochratoxin A, its opened lactone and several of its analogs:
structure-activity relationships. Toxicol. Appl. Pharmacol. 137:182-192.
Zhang, Z. R.R. Marquardt, G. Wang, W. Guenter, G.H. Crow, Z. Han and M.R.
Bedford. 1996. A simple model for predicting the response of chicks to dietary
enzyme supplementation. J. Anim. Sci. 74:394-402.
Li, S., P.Y. Chen, R.R. Marquardt, Z. Han and J.R. Clarke. 1996. Production of a
sensitive monoclonal antibody to sterigmatocystin and its application to ELISA of
wheat. J. Agric. Food Chem. 44:372-375.
Wang, N., D. Kierek-Jaszczuk, R.R. Marquardt, A.A. Frohlich and D. Abramson. 1996.
Use of a heterologous bridge coating antigen for the immunoassay of 3acetyldeoxynivalenol in barley. J. Food Prot. 59:525-533.
Xiao, H., J.R. Clarke, R.R. Marquardt, A.A. Frohlich. 1995. Improved methods for
conjugating selected mycotoxins to carrier proteins and dextran for immunoassays.
J. Agric. Food Chem. 43:2092-2097.
Boros, D., R.R. Marquardt and W. Guenter. 1995. Rye as an alternative grain in
commercial broiler feeding. J. Appl. Poultry Res. 4:341-351.
Blank, G., N. Goswami, F. Madrid, R.R. Marquardt and A.A. Frohlich. 1995.
Evaluation of Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) excreta in
ochratoxin production in stored wheat. J. Stored Prod. Res. 31:151-155.
Nada, S.A., M.S. Arbid, A.H. Mohamed, M.S. Hanafy, M.M. El-Mahdy, R.R. Marquardt
and M.I. Dessouky. 1995. Clinicopathological studies on the protective effect of Lphenylalanine against experimental ochratoxicosis in rats. Egypt. J. Comp. Pathol.
Clin. Pathol. 8:57-72.
Clarke, J.R., R.R. Marquardt, and A.H. Frohlich. 1995. Comparative studies on the
specificity and sensitivity of rabbit and laying hen antisera to ochratoxin A. Food
Agric. Immunol. 7:33-42.
Lu P., R.R. Marquardt, A.A. Frohlich and J.T. Mills. 1995. The development of a solidphase immunoassay for the detection and identification of Aspergillus ochraceus in
wheat grain. Food Agric. Immunol. 7:81-93.
Kierek-Jaszczuk, D., R.R. Marquardt, A.A. Frohlich, J. Clarke, H. Xiao, and D.
Abramson. 1995. Detection and quantitation of the T-2 mycotoxin by enzyme linked
immunosorbent assays utilizing toxin specific polyclonal antibodies raised in
chickens. Food Agric. Immunol. 7:243-252.
Lu, P., R.R. Marquardt, and D. Kierek-Jaszczuk. 1995. Immunochemical identification
of fungi using polyclonal antibodies raised in rabbits to exoantigens from Aspergillus
ochraceus. Lett. Appl. Microbiol. 20:41-45.
Xiao, H., R.R. Marquardt, and A.A. Frohlich. 1995. Synthesis and structural
elucidation of analogs of ochratoxin A. J. Agric. Food Chem. 43:524-530.
Nada, S.A., M.S. Arbid, R.R. Marquardt. 1994. Protective effect of L-cysteine on
ochratoxicosis in rats. J. Egypt. Soc. Toxicol. 12:33-40.
Lu, P., R.R. Marquardt, A.A. Frohlich and J.T. Mills. 1994. Detection of Penicillium
aurantiogriseum by ELISA utilizing antibodies produced against its exoantigens.
Microbiology 140:3267-3276.
Madhyastha, M.S., R.R. Marquardt and D. Abramson. 1994. Structure - activity
relationships and interactions among trichothecene mycotoxins as assessed by a
yeast bioassay. Toxicon 32:1147-1152.
Li, S., R.R. Marquardt, A.A. Frohlich, H. Xiao, and J.R. Clarke. 1994. The
development of a quantitative ELISA for aflatoxin B1 in ground peanuts using
antibodies isolated from the yolk of a laying hen. J. Food Protection 57:1022-1024.
12
80. Clarke, J.R., R.R. Marquardt, A.A. Frohlich and R.J. Pitura. 1994. Quantification of
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
96.
ochratoxin A in swine kidneys by an enzyme-linked immunosorbent assay using a
simplified sample preparation procedure. J. Food Protection 57:991-995.
Madhyastha, M.S., R.R. Marquardt, A.A. Frohlich and J. Borsa. 1994. Optimization of
a yeast assay for trichothecene mycotoxins. J. Food Protection 57:490-495.
Madhyastha, M.S., R.R. Marquardt, A. Masi, J. Borsa and A.A. Frohlich. 1994.
Comparison of toxicity of different mycotoxins to several species of bacteria and
yeasts: Use of Bacillus brevis in a disc diffusion assay. J. Food Protection. 57:48-53.
Jansman, A.J.M., A.A. Frohlich and R.R. Marquardt. 1994. Production of proline-rich
proteins by the parotid glands of rats fed diets containing tannins from faba beans
(Vicia faba L.) J. Nutrition 124:249-258.
Marquardt, R.R., D. Boros, W. Guenter and G. Crow. 1994. The nutritive value of
barley, rye, wheat and corn for chicks as affected by the use of Trichoderma reesei
enzyme preparation. Anim. Feed Sci. Tech. 45:363-378.
Madhyastha, M.S., R.R. Marquardt, and D. Abramson. 1993. Effect of ochratoxin
producing fungi on the chemical composition of wheat and barley. J. Food Quality,
16:287-299.
Clarke, J.R., R.R. Marquardt, A. Oosterveld A.A. Frohlich, F.J. Madrid and M. Dawood.
1993. Development of a quantitative and sensitive enzyme-linked immunosorbent
assay for ochratoxin A using antibodies from the yolk of the laying hen. J. Agric.
Food Chem. 41:1764-1789
Madhyastha, M.S., R.R. Marquardt and A.A. Frohlich. 1993. Growth and ochratoxin
production of Aspergillus alutaceus on seed of wheat and rapeseed cultivars. Can. J.
Plant Sci. 73:163-166.
Terse, P.S., M.S. Madhyastha, O. Zurovac, D. Stringfellow, R.R. Marquardt and B.W.
Kemppainen. 1993. Comparison of in vitro and in vivo biological activity of
mycotoxins. Toxicon, 31:913-919.
Boros, D., R.R. Marquardt, B.A. Slominski and W. Guenter. 1993. Extract viscosity as
an indirect assay for water-soluble pentosan content in rye. Cereal Chemistry.
70:575-580.
Brenes, A., W. Guenter, R.R. Marquardt and B.A. Rotter. 1993. Effect of enzyme
supplemented on the performance of chickens and laying hens fed wheat, barley,
naked oats and rye diets. Can. J. Animal Sci. 73:941-951.
Brenes, A., M. Smith, W. Guenter and R.R. Marquardt. 1993. Effect of enzyme
supplementation on the performance and digestive tract size of broiler chickens fed
wheat and barley-based diets. Poultry Sci. 72:1731-1739.
Brenes, A., B.A. Rotter, R.R. Marquardt and W. Guenter. 1993. The nutritional value
of raw- autoclaved and dehulled peas (Pisum sativum L.) in chicken diets as affected
by enzyme supplementation. Can. J. Animal Sci. 73:605-614.
Brenes, A., R.R. Marquardt, W. Guenter and B.A. Rotter. 1993. Effect of enzyme
supplementation on the nutritional value of raw, autoclaved and dehulled lupins
(Lupinus albus) in chicken diets. Poultry Sci. 72:2281-2293.
Arbid, M.S.S., M.S. Madhyastha, R.R. Marquardt and A.A. Frohlich. 1993. Effect of
neomycin on the hydrolyses and toxicity of vicine and convicine in rats. Fd. Chem.
Toxic. 31:835-840.
Haazele, F.M., W. Guenter, R.R. Marquardt and A.A. Frohlich. 1993. Beneficial effects
of dietary ascorbic acid supplementation on hens subjected to ochratoxin A toxicosis
under normal and high ambient temperatures. Can. J. Anim. Sci. 73:149-157.
Friesen, O.D., W. Guenter, R.R. Marquardt and B.A. Rotter. 1992. The effect of
enzyme supplementation on the apparent metabolizable energy and nutrient
digestibilities of wheat, barley, oats and rye for the young broiler chick. Poultry Sci.
71:1710-1721.
13
97. Borsa, J., W.S. Chelack, R.R. Marquardt and A.A. Frohlich. 1992. Comparison of
irradiation and chemical fumigation on production of ochratoxin A by Aspergillus
alutaceus in treated barley. J. Food Protection. 55:990-994.
98. Madhyastha, M.S., R.R. Marquardt and A.A. Frohlich. 1992. Hydrolysis of ochratoxin
A by the microbial activity of digesta in the gastrointestinal tract. Arch. Envir.
Contam. Toxicol. 23:468-472.
99. Madhyastha, M.S., A.A. Frohlich and R.R. Marquardt. 1992. Effect of dietary
cholestyramine on the elimination pattern of ochratoxin A in rats. Food Chem.
Toxicol. 30:709-714.
100.
Lippold, C.C., S.C. Stothers, A.A. Frohlich, R.J. Boila and R.R. Marquardt.
1992. Effects of periodic feeding of diets containing ochratoxin A on the performance
and clinical chemistry of pigs from fifteen to twenty kilograms body weight. Can. J.
Anim. Sci. 72:135-146.
101.
Park, I-K., S. Shin and R.R. Marquardt. 1991. Effects of niacin deficiency on
the relative turnover rates of proteins in various tissues of Japanese Quail. Inter. J.
Biochem. 23:1005-1012.
102.
Szekely, J.G., W.S. Chelack, S. Delang, R.R. Marquardt and A.A. Frohlich.
1991. Scanning electron microscope observations of growth and ochratoxin A
production of Aspergillus alutaceus (formerly A. ochaceus) on gamma-irradiated
barley. Food Structure 10:295-302.
103.
Friesen, O.D., W. Guenter, R.R. Marquardt and B.A. Rotter. 1991. The effects
of enzyme supplementation on the nutritive value of rye grain (Secale cereale) for
the young broiler chick. Poultry Sci. 70:2501-2508.
104.
Rotter, R.G., R.R. Marquardt and C.G Campbell. 1991. The nutritional value of
low lathyrogenic lathyrus (Lathyrus sativus) for growing chicks. Brit. Poultry Sci.
32:1055-1067.
105.
Chelack, W.S., J. Borsa, R.R. Marquardt, and A.A. Frohlich. 1991. Role of
competitive microbial flora in the radiation-induced enhancement of ochratoxin
production by Aspergillus alutaceus var alutaceus NRRL-3174. Appl. Environ.
Microbiol. 57:2492-2496.
106.
Chelack, W.S., J. Borsa, J.G. Szekely, R.R. Marquardt, and A.A. Frohlich.
1991. Variants of Aspergillus alutaceus var alutaceus (formerly Aspergillus ochaceus)
with altered ochratoxin A production. Appl. Environ. Microbiol. 57:2487-2491.
107.
Roberts, C.A., R.R. Marquardt, A.A. Frohlich, R.L. McGraw, R.G. Rotter and
J.C. Henning. 1991. Chemical and spectral quantification of mold in contaminated
barley. Cereal Chem. 68:272-275.
108.
Xiao, H., R.R. Marquardt, A.A. Frohlich, G.D. Phillips and T.G. Vitti. 1991.
Effect of a hay and a grain diet on the bioavailability of ochratoxin A in the rumen of
sheep. J. Anim. Sci. 69:3715-3723.
109.
Xiao, H., R.R. Marquardt, A.A. Frohlich, G.D. Phillips and T.G. Vitti. 1991.
Effect of a hay and a grain diet on the rate of hydrolysis of ochratoxin A in the rumen
of sheep. J. Anim. Sci. 69:3706-3714.
110.
Castanon, J.I.R. and R.R. Marquardt. 1991. Some factors affecting true
metabolizable energy of faba beans (Vicia faba L.). Poultry Sci. 70:568-572.
111.
Rotter, B.A., R.R. Marquardt, W. Guenter, L.D. Campbell and G.H. Crow.
1990. Estimation of nitrogen-corrected true metabolizable energy of two different
barley samples with and without enzyme supplementation over different excreta
collection times. Poultry Sci. 69:1816-1817.
112.
Rotter, R.G., R.R. Marquardt, R. K-C. Low and C.J. Briggs. 1990. Influence of
autoclaving on the effects of Lathyrus sativa fed to chicks. Can. J. Animal Sci.
70:739-741.
14
Low, R. K-C., R.G. Rotter, R.R. Marquardt and G. C. Campbell. 1990. Use of
Lathyrus sativus L. (var. seminis albi) as a foodstuff for poultry. Brit. Poultry Sci.
31:641-651.
114.
Madhyastha, M.S., R.R. Marquardt, A.A. Frohlich, G. Platford and D.
Abramson. 1990. Effects of different cereal and oilseed substrates on the growth and
production of toxins by Aspergillus alutaceus and Penicillium verrucosum. J. Agric.
Food Chem. 38:1506-1510.
115.
Rotter, B.A., R.R. Marquardt, W. Guenter and G.H. Crow. 1990. Evaluation of
three enzymatic methods as predictors of in vivo response to enzyme
supplementation of barley-based diets when fed to young chicks. J. Sci. Food Agric.
50:19-27.
116.
Rotter, R.G., R.R. Marquardt, A.A. Frohlich and D. Abramson. 1990.
Ensilaging as a means of reducing ochratoxin A concentrations in contaminated
barley. J. Sci. Food Agric. 50:155-166.
117.
Pawlik, J.R., A.I. Fengler and R.R. Marquardt. 1990. Improvement of the
nutritional value of rye by the partial hydrolysis of viscous water-soluble pentosans
following water-soaking a fungal enzyme treatment. Brit. Poultry Sci. 31:549-562.
Rotter, B.A., O.D. Friesen, W. Guenter and R.R. Marquardt. 1990. Influence of
enzyme supplementation in the bioavailable energy of barley. Poultry Sci. 69:11741181.
118.
Mills, J.T., D. Abramson, A.A. Frohlich and R.R. Marquardt. 1990. Citrinin and
ochratoxin A production by Penicillium spp. from stored Amber Durum wheat. Can. J.
Plant Path. 11:357-360.
119.
Rotter, R.G., A.A. Frohlich and R.R. Marquardt. 1989. Influence of dietary
manipulation on the detrimental effects of mold-contaminated barley fed to growing
chicks. Can. J. Anim. Sci. 69:1059-1066.
120.
Mills, P.A., R.G. Rotter and R.R. Marquardt. 1989. Modification of the
glucosamine method for the quantification of fungal contamination. Can. J. Anim.
Sci. 69:1105-1106.
121.
Rotter, B.A., R.R. Marquardt, W. Guenter, C. Biliaderis and C.W. Newman.
1989. In vitro viscosity measurements of barley extracts as predictors of growth
response in chicks fed barley-based diets supplemented with a fungal enzyme
preparation. Can. J. Anim. Sci. 69:431-439.
122.
Marquardt, R.R., M.S.S. Arbid and A.A. Frohlich. 1989. Preparation of
crystalline isouramil from convicine by acid hydrolysis and isolation of two
decomposition products of isouramil. J. Agric. Food Chem. 37:448-454.
123.
Marquardt, R.R., A.A. Frohlich and M.S.S. Arbid. 1989. Isolation of crystalline
divicine from an acid hydrolysate of vicine and a crystalline decomposition product of
divicine and some properties of these compounds. J. Agric. Food Chem. 37:455-462.
124.
Rotter, R.G., A.A. Frohlich and R.R. Marquardt. 1989. Influence of dietary
charcoal on ochratoxin A toxicity in leghorn chicks. Can. J. Vet. Res. 53:449-453.
125.
Rotter, R.G., R.R. Marquardt and A.A. Frohlich. 1989. Ochratoxin A toxicity in
growing chicks. Effect of supplemental dietary phenylalanine. Nutrition Reports Inter.
40:1091-1100.
126.
Sreemannarayana, O., R.R. Marquardt, A.A. Frohlich, D. Abramson and G.D.
Phillips. 1989. Organ weights, liver constituents and serum components in growing
chicks fed ochratoxin A. Arch. Environ. Contam. Toxicol. (Invited paper) 18:404-410.
127.
Castanon, J.I.R. and R.R. Marquardt. 1989. Effect of enzyme addition,
autoclave treatment and fermenting on the nutritive value of field beans (Vicia faba
L.). Anim. Feed Sci. Tech. 26:71-99.
128.
Rotter, R.G., A.A. Frohlich and R.R. Marquardt. 1989. Comparison of the
effects of toxin-free and toxin-containing mold-contaminated barley on chick
performance. Can. J. Anim. Sci. 69:247-259.
113.
15
Rotter, B.A., A.A. Frohlich, R.G. Rotter and R.R. Marquardt. 1989. Estimation
of apparent protein digestibility using uric acid corrected nitrogen values in poultry
excreta. Poultry Sci. 68:327-329.
130.
Rotter, R.G., A.A. Frohlich, R.R. Marquardt and P.A. Mills. 1989. Estimation of
fungal contamination of cereal grain as determined by measuring glucosamine
concentration. Can. J. Anim. Sci. 69:235-245.
131.
Rotter, B.A., M. Neskar, R.R. Marquardt and W. Guenter. 1989. Effects of
different enzyme preparations on the nutritional value of barley in chicken diets.
Nutr. Reports. Inter. 39:107-120.
132.
Rotter, B.A., M. Neskar, W. Guenter and R.R. Marquardt. 1989. Effect of
enzyme supplementation on the nutritive value of hulless barley in chicken diets.
Anim. Feed Sci. and Tech. 24:233-245.
133.
Sreemannarayana, O., A.A. Frohlich, R.R. Marquardt and W. Guenter. 1989.
The relative growth of internal organs of single comb white leghorn birds. Indian Vet.
J. 66:636-639.
134.
Sreemannarayana, O., R.R. Marquardt, A.A. Frohlich and W. Guenter. 1989.
Enzyme activities, protein, metabolites and electrolyte concentrations in the serum of
single comb white leghorn chickens. Indian Vet. J. 66:435-440.
135.
Marquardt, R.R. and M.S.S. Arbid. 1988. Protection against the toxic effects of
the favism factor (Divicine) in rats by vitamin E, A and C and iron chelating agents.
J. Sci. Food Agric. 43:155-166.
136.
Arbid, M.S.S., and R.R. Marquardt. 1988. Favism-like effects of divicine and
isouramil in the rat: acute and chronic effects on animal health, mortalities, blood
parameters and ability to exchange respiratory gases. J. Sci. Food Agric. 43:75-90.
137.
Marquardt, R.R., A.A. Frohlich, O. Sreemannarayana, D. Abramson, and A.
Bernatsky. 1988. Ochratoxin A in blood from slaughtered pigs in Western Canada.
Can. J. Vet. Res. 52:186-190.
138.
Frohlich, A.A., R.R. Marquardt and A. Bernatsky. 1988. Quantification of
Ochratoxin A: The use of reverse-phase TLC for sample cleanup followed by HPLC or
direct fluorescency measurement. J. Assoc. Off. Anal. Chem. 71:949-953.
139.
Sreemannarayana, O., R.R. Marquardt and A.A. Frohlich. 1988. Effects of
repeated intra-abdominal injections of sterigmatocystin on relative organ weights, on
the concentration of serum and liver constituents and histopathology of certain
organs of the chick. Poultry Sci. 67:502-509.
140.
Sreemannarayana, O., A.A. Frohlich, T.G. Vitti, R.R. Marquardt and D.
Abramson. 1988. Ochratoxin A in calves. Studies on the tolerance and disposition of
ochratoxin A in young calves. J. Anim. Sci. 66:1703-1711.
141.
Fengler, A.I., J.R. Pawlik and R.R. Marquardt. 1988. Improvement in nutrient
retention and changes in excreta viscosities in chicks fed rye containing diets
supplemented with fungal enzymes, sodium taurochalate and penicillin. Can. J. Anim.
Sci. 68:483-491.
142.
Fengler, A.I. and R.R. Marquardt. 1988. Antinutritive properties of the watersoluble pentosans from rye: I. Isolation, partial purification and characterization of
the factor. Cereal Chem. 65:291-297.
143.
Fengler, A.I. and R.R. Marquardt. 1988. Water-soluble pentosans from rye: II.
Effects on rate of dialysis and the retention of nutrients by the chick. Cereal Chem.
65:298-302.
144.
Ward, A.T. and R.R. Marquardt. 1988. Effects of various treatments on the
nutritive value of rye or rye fractions. Brit. Poultry Sci. 29:709-720.
145.
Sreemannarayana, O., A.A. Frohlich and R.R. Marquardt. 1987. Acute toxicity
of sterigmatocystin to chicks. Mycopathologia. 97:51-59.
146.
Frohlich, A.A., O. Sreemannarayana, and R.R. Marquardt. 1987. An improved
procedure for fecal collection in calves. Can. J. Anim. Sci. 67:213-215.
129.
16
Ward, A.T. and R.R. Marquardt. 1987. Antinutritional activity of a watersoluble pentosan-rich fraction from rye grain. Poultry Sci. 66:1665-1674.
148.
Yannai, S. and R.R. Marquardt. 1987. Effects of divicine, one of its
degradation products and hydrogen peroxide on normal and pre-treated rat
erythrocytes. Vet. Human Toxicol. 29:373-380.
149.
Arbid, M.S.S. and R.R. Marquardt. 1986. Effects of intraperitoneally injected
vicine and convicine on the rat: induction of favism-like signs. J. Sci. Food Agric.
37:539-547.
150.
Hussein, L., H. Motawei, A. Nassib, S. Khalil and R.R. Marquardt. 1986. The
complete elimination of vicine and convicine from the faba bean by combinations of
genetic selection and processing techniques. Qual. Plant Food Human Nutr. 36:231242.
151.
Sreemannarayana, O., R.R. Marquardt, A.A. Frohlich and J.F.A. Juck. 1986.
Some acute biochemical and pathological changes in chicks after oral administration
of sterigmatocystin. J. Amer. College Toxicol. 5:275-287.
152.
Sreemannarayana, O., A.A. Frohlich, and R.R. Marquardt. 1986. Serum
biochemical studies in chicks injected intraperitoneally with sterigmatocystin. Poultry
Advisor. 19:53-57.
153.
Arbid, M.S.S. and R.R. Marquardt. 1985. Hydrolysis of the toxic constituents
(vicine and convicine) in Faba bean (Vicia faba L.) food preparations following
treatment with ß-glucosidase. J. Sci. Food Agric. 36:839-846.
154.
Yannai, S. and R.R. Marquardt. 1985. Induction of favism-like symptoms in
the rat: effects of vicine and divicine in normal and buthionine-sulfoxamine treated
rats. J. Sci. Food Agric. 36:1161-1168.
155.
Arbid, M.S.S. and R.R. Marquardt. 1985. A modified procedure for the
purification of vicine and convicine from faba beans (Vicia faba L.). J. Sci. Food Agric.
36:1266-1270.
156.
Arbid, M.S.S., R.R. Marquardt and M.M.E. El-Habbah. 1985. A study of the
toxic effects of high levels of dehulled faba beans. (Vicia faba L.) in the diet of laying
hens. Egyptian Poultry Sci. 5:26-50.
157.
Rotter, R.G., R.R. Marquardt and J.C. Young. 1985. Effect of ergot from
different sources and a fractionated ergot on the performance of growing chicks.
Can. J. Anim. Sci. 65:953-961.
158.
Rotter, R.G., R.R. Marquardt and G.H. Crow. 1985. A comparison of the effect
of increasing dietary concentrations of wheat ergot on the performance of leghorn
and broiler chicks. Can. J. Anim. Sci. 65:963-974.
159.
Rotter, R.G., R.R. Marquardt and J.C. Young. 1985. The ability of growing
chicks to recover from short term exposure to dietary wheat ergot and the effect of
chemical and physical treatments on ergot toxicity. Can. J. Anim. Sci. 65:975-983.
160.
Hegazy, M.I. and R.R. Marquardt. 1984. Metabolism of vicine and convicine in
rat tissues: absorption and excretion patterns and site of hydrolysis. J. Sci. Food
Agric. 35:139-146.
161.
Marquardt, R.R., D.S. Muduuli and A.A. Frohlich. 1983. Purification and some
properties of vicine and convicine isolated from Faba bean (Vicia faba L.) protein
concentrate. J. Agric. Food Chem. 31:839-844.
162.
Frohlich, A.A. and R.R. Marquardt. 1983. Turnover and hydrolysis of vicine
and convicine in avian tissues and digesta. J. Sci. Food Agric. 34:153-163.
163.
Hegazy, M.I. and R.R. Marquardt. 1983. Development of a simple procedure
for the complete extraction of vicine and convicine from faba beans (Vicia faba L.). J.
Sci. Food Agric. 34:100-108.
164.
Buckley, K.E., T.J. Devlin and R.R. Marquardt. 1983. Factors affecting in vitro
rumen digestion of faba bean cultivars (Vicia faba L.). Can. J. Anim. Sci. 63:89-96.
147.
17
Gardiner, E.E., R.R. Marquardt and G. Kemp. 1983. Variation in vicine and
convicine concentration of faba bean genotypes. Can. J. Plant Sci. 62: 589-592.
166.
Marquardt, R.R. 1983. A simple spectrophotometric method for the direct
determination of uric acid in avian excreta. Poultry Sci. 62:2106-2108.
167.
Marquardt, R.R., A.T. Ward and L.D. Campbell. 1983. A rapid highperformance liquid chromatographic method for the quantification of uric acid in
excreta and tissue samples. Poultry Sci. 62:2099-2105.
168.
Young, J.C., Z-J Chen and R.R. Marquardt. 1983. Reduction in alkaloid
content of ergot sclerotia by chemical and physical treatment. J. Agric. Food Chem.
31:413-415.
169.
Ward, A.T. and R.R. Marquardt. 1983. Effect of saturation, chain length of
pure triglycerides and age of bird on the utilization of rye diets. Poultry Sci. 62:10541062.
170.
Antoniou, T.C. and R.R. Marquardt. 1983. The utilization of rye by growing
chicks as influenced by autoclave treatment, water extraction and water soaking.
Poultry Sci. 62:91-102.
171.
Park, I.K. and R.R. Marquardt. 1982. Effects of niacin deficiency on pyridine
nucleotide levels and enzyme activities in various organs of young growing quail. J.
Nutr. 112:863-873.
172.
Park, I.K. and R.R. Marquardt. 1982. Effects of sulfaquanidine and amino acid
imbalances on the induction of niacin deficiency in mature and immature Japanese
quail (Coturnix Japonica). Poultry Sci. 6:1329-1334.
173.
Muduuli, D.S., R.R. Marquardt and W. Guenter. 1982. Effect of vicine and
vitamin E supplementation on the productive performance of growing and laying
chickens. Brit. J. Nutr. 47:53-59.
174.
Antoniou, T.C. and R.R. Marquardt. 1982. Utilization of rye diets by chicks as
affected by lipid type and level of penicillin supplementation. Poultry Sci. 61:107116.
175.
Young, S.C. and R.R. Marquardt. 1982. Effects of ergotamine tartrate on
growing chickens. Can. J. Anim. Sci. 62:1181-1191.
176.
Buckley, W.T. and R.R. Marquardt. 1981. Estimation of whole body protein
synthesis in rats by single injection of L-(1-14C) leucine or DL-(1-14C) lysine. J.
Nutr. 111:763-771.
177.
Buckley, W.T., R.R. Marquardt and A.T. Ward. 1981. Effect of rate of
catabolism of DL-(1-14C) lysine on estimation of whole body protein synthesis in
rats. J. Nutr. 111:772-776.
178.
Marquardt, R.R. and A.A. Frohlich. 1981. Rapid reverse-phase highperformance liquid chromatographic method for quantitations of vicine and convicine.
J. Chrom. 208:373-379.
179.
Olaboro, G., R.R. Marquardt and L.D. Campbell. 1981. Isolation of the egg
weight depressing factor in faba beans (Vicia faba L.). J. Sci. Food Agric. 32:10741080.
180.
Olaboro, G., R.R. Marquardt and L.D. Campbell. 1981. Purification,
identification and quantitation of an egg weight depressing factor (vicine) in faba
beans (Vicia faba L.). J. Sci. Food Agric. 32:1163-1171.
181.
Muduuli, D.S., R.R. Marquardt and W. Guenter. 1981. Effect of dietary vicine
on the productive performance of laying chickens. Can. J. Anim. Sci. 61: 757-764.
182.
Olaboro, G., L.D. Campbell and R.R. Marquardt. 1981. Influence of Faba bean
fractions on egg weight among laying hens fed test diets for a short time period.
Can. J. Anim. Sci. 61:751-755.
183.
Yu, J.Y.L. and R.R. Marquardt. 1981. Growth patterns of sex hormone target
organs of the female domestic chicken (Gallus domesticus). Chinese Bioscience.
17:17-32.
165.
18
Antoniou, T., R.R. Marquardt and P.E. Cansfield. 1981. Isolation, partial
characterization and antinutritional activity of a factor (pentosans) in rye grain. J.
Agric. Food Chem. 29:1240-1247.
185.
Antoniou, T. and R.R. Marquardt. 1981. Influence of rye pentosans on the
growth of chicks. Poultry Sci. 60:1898-1904.
186.
Cansfield, P.E., R.R. Marquardt and L.D. Campbell. 1980. Condensed proanthocyanidins of faba beans. J. Sci. Food Agric. 31:802-812.
187.
Buckley, W.T. and R.R. Marquardt. 1980. Preparation of L- and D-(1-14C)
lysine by the resolution of DL-(1-14C) lysine. Prep. Biochem. 10:85-91.
188.
Buckley, W.T. and R.R. Marquardt. 1980. Diurnal variation in oxidation of L(1-14C) lysine in rats. J. Nutr. 110:974-984.
189.
Olaboro, G., L.D. Campbell and R.R. Marquardt. 1980. Performance of hens
fed on diets containing heat treated beans (Vicia faba), cotyledons and hulls. J.
Agric. Sci., Camb. 95:697-701.
190.
Campbell, L.D., G. Olaboro, R.R. Marquardt and D. Waddell. 1980. Use of
faba beans in diets for laying hens. Can. J. Anim. Sci. 60:395-405.
191.
Antoniou, T., R.R. Marquardt and R. Misir. 1980. The utilization of rye by
growing chicks as influenced by calcium, vitamin D3 and fat type and level. Poultry
Sci. 59:758-769.
192.
Marquardt, R.R. and A.T. Ward. 1979. Chick performance as affected by
autoclave treatment of tannin-containing and tannin-free cultivars of faba beans.
Can. J. Anim. Sci. 59:781-789.
193.
Marquardt, R.R., A.T. Ward and R. Misir. 1979. The retention of nutrients by
chicks fed rye diets supplemented with amino acids and penicillin. Poultry Sci.
58:631-640.
194.
Marquardt, R.R., J.A. McKirdy and A.T. Ward. 1978. Comparative cell wall
constituent levels of tannin-free and tannin-containing cultivars of faba beans (Vicia
faba L.). Can. J. Anim. Sci. 58:775-781.
195.
Bush, R.S. and R.R. Marquardt. 1978. Effect of starvation and molecular
weight on the turnover of soluble proteins from five tissues in Japanese Quail. J.
Nutr. 108:301-306.
196.
Bush, R.S. and R.R. Marquardt. 1978. Effect of age, sex and starvation on the
turnover of plasma, liver and breast muscle in Japanese Quail. J. Nutr. 108:296-300.
197.
Marquardt, R.R., A.T. Ward and L.E. Evans. 1978. Comparative properties of
tannin-free and tannin-containing cultivars of faba beans (Vicia faba). Can. J. Plant
Sci. 58:753-760.
198.
Misir, R. and R.R. Marquardt. 1978. Factors affecting rye (Secale cereale L.)
utilization in growing chicks. I. The influence of rye level, ergot and penicillin
supplementation. Can. J. Anim. Sci. 58:691-701.
199.
Misir, R. and R.R. Marquardt. 1978. Factors affecting rye (Secale secale L.)
utilization in growing chicks. II. The influence of protein type, protein level and
penicillin. Can. J. Anim. Sci. 58:703-715.
200.
Misir, R. and R.R. Marquardt. 1978. Factors affecting rye (Secale cereale L.)
utilization in growing chicks. III. The influence of milling fractions. Can. J. Anim. Sci.
58:717-730.
201.
Misir, R. and R.R. Marquardt. 1978. Factors affecting rye (Secale cereale L.)
utilization in growing chicks. IV. The influence of autoclave treatment, pelleting,
water extraction and penicillin supplementation. Can. J. Anim. Sci. 58:731-742.
202.
Marquardt, R.R., A.T. Ward, L.D. Campbell and P.E. Cansfield. 1977.
Purification, identification and characterization of a growth inhibitor in faba beans
(Vicia faba L. var. minor). J. Nutr. 107:1313-1324.
184.
19
Ward, A.T., R.R. Marquardt and L.D. Campbell. 1977. Further studies on the
isolation of the thermolabile growth inhibitor from faba beans (Vicia faba L. var.
minor). J. Nutr. 107:1325-1334.
204.
Campbell, L.D. and R.R. Marquardt. 1977. Performance of broiler chicks fed
diets of varying energy density and containing varied levels of raw or heat-treated
faba beans. Poultry Sci. 56:442-448.
205.
Marquardt, R.R., L.D. Campbell and T. Ward. 1976. Studies with chicks on the
growth depressing factors in faba beans (Vicia faba L. var. minor). J. Nutri. 106:275284.
206.
Yu, J. Y-L., L.D. Campbell and R.R. Marquardt. 1976. Immunological and
compositional patterns of lipoproteins in chicken (Gallus domesticus) plasma. Poultry
Sci. 55:1626-1631.
207.
Marquardt, R.R. 1975. Comparative physical chemical and enzymatic
properties of the isozymic forms of avian aldolases and fructose diphosphatases.
Isozymes II - Physiological Functions, edited by C.L. Markert, pp. 767-783. Academic
Press.
208.
Marquardt, R.R. and J.P. Olson. 1975. Comparative enzymatic properties of
avian liver and skeletal muscle D-fructose-1, 6-diphosphate, 1 phosphohydrolase.
Can. J. Biochem. 53:1214-1219.
209.
Marquardt, R.R., J.A. McKirdy, T. Ward and L.D. Campbell. 1975. Amino acid,
hemagglutinin and trypsin inhibitor levels, and proximate analyses of faba beans
(Vicia faba L. var. minor) and Faba bean fractions. Can. J. Anim. Sci. 55:421-429.
210.
Marquardt, R.R. and L.D. Campbell. 1975. Performance of chicks fed Faba
bean (Vicia faba L. var. minor) diets supplemented with methionine, sulfate and
cystine. Can. J. Anim. Sci. 55:213-218.
211.
Marquardt, R.R. and J.P. Olson. 1974. Thermal inactivation of avian liver and
muscle fructose 1,6-diphosphatase in the presence of fructose 1,6-diphosphate, AMP
and divalent cations. Can. J. Biochem. 52:670-678.
212.
Marquardt, R.R., and L.D. Campbell. 1974. Deficiency of methionine in raw
and autoclaved faba beans in chick diets. Can. J. Anim. Sci. 54:437-442.
213.
Yu, J. Y-L., P. Yuthasastrakosol, R.R. Marquardt and W.M. Palmer. 1974.
Estrogen levels in peripheral plasma of immature female chickens as determined by
radioimmunoassay. Endocrinology. 94:1168-1171.
214.
Yu, J. Y-L. and R.R. Marquardt. 1974. Hyperplasia and hypertrophy of the
chicken (Gallus domesticus) oviduct during a reproductive cycle. Poultry Sci.
53:1096-1105.
215.
Marquardt, R.R., L.D. Campbell, S.C. Stothers and J.A. McKirdy. 1974. Growth
responses of chicks and rats fed diets containing four cultivars of raw or autoclaved
faba beans (Vicia faba L. var. minor). Can. J. Anim. Sci. 54:177-182.
216.
Yu, J. Y-L. and R.R. Marquardt. 1973. Synergism of testosterone and estradiol
in the development and function of the magnum from the immature chicken (Gallus
domesticus) oviduct. Endocrinology. 92:563-571.
217.
Yu, J. Y-L., A.A. Frohlich and R.R. Marquardt. 1973. Effects of estradiol and
testosterone on cyclic AMP levels in certain tissues of domestic fowl (Gallus
domesticus). Comp. Biochem. Physiol. 46A:215-220.
218.
Yu, J. Y-L. and R.R. Marquardt. 1973. Development, cellular growth and
function of the avian oviduct: I. Biochemical and morphological studies on the
magnum portion of the domestic fowl (Gallus domesticus) oviduct during a
reproductive cycle. Biol. Reprod. 8:282-298.
219.
Salem, H.A., T.J. Devlin and R.R. Marquardt. 1973. Effect of urea on the
activity of glutamate dehydrogenase, glutamine synthetase in ruminant tissues. Can.
J. Anim. Sci. 53:503-511.
203.
20
Marquardt, R.R. and L.D. Campbell. 1973. Raw and autoclaved faba beans in
chick diets. Can. J. Anim. Sci. 53:741-746.
221.
Yu, J. Y-L. and R.R. Marquardt. 1973. Interaction of estradiol and
testosterone in the regulation of growth and development of the chicken (Gallus
domesticus) oviduct. Comp. Biochem. Physiol. 44B:769-777.
222.
Bush, R.S. and R.R. Marquardt. 1973. Effects of acid, base and ammonium
sulfate on the protein binding properties of methylmercury in cytoplasmic
preparations from avian liver and kidney. Can. J. Anim. Sci. 53:647-651.
223.
Bush, R.S., L.D. Campbell, R.R. Marquardt and F.A.J. Armstrong. 1973.
Intracellular distribution of mercury in avian tissues. Can. J. Anim. Sci. 53:197-204.
224.
Yu, J. Y-L. and R.R. Marquardt. 1973. Effects of estradiol and testosterone on
the immature female chicken (Gallus domesticus). II. Immunodiffusional patterns of
yolk lipoproteins in the liver and plasma. Comp. Biochem. Physiol. 46B:759-767.
225.
Yu, J. Y-L. and R.R. Marquardt. 1973. Effects of estradiol and testosterone on
the immature female chicken (Gallus domesticus). I. Qualitative changes in nucleic
acids, proteins and lipids in the liver. Comp. Biochem. Physiol. 46A:749-757.
226.
Frohlich, A.A. and R.R. Marquardt. 1972. Cyclic AMP levels in various tissues
of the domestic fowl (Gallus domesticus) as affected by glucagon, epinephrine and
insulin. Biochem. Biophys. Acta. 286:396-405.
227.
Olson, J.P. and R.R. Marquardt. 1972. Avian fructose-1, 6-diphosphatases. I.
Purification and comparison of physical and immunological properties of the liver and
breast muscle enzymes from chickens (Gallus domesticus). Biochem. Biophys. Acta.
263:453-467.
228.
Yu, J. Y-L., R.R. Marquardt and G.C. Hodgson. 1972. Development, cellular
growth and function of the avian oviduct. II. A comparative study of the changes of
cellular components in each region of domestic fowl (Gallus domesticus) oviduct
during a reproductive cycle. Can. J. Phys. Pharm. 50:689-696.
229.
Yu, J. Y-L., R.R. Marquardt and P.A. Kondra. 1972. Development, cellular
growth and function of the avian oviduct. III. Electrophoretic and immunological
patterns of soluble proteins from each region of domestic fowl (Gallus domesticus)
oviduct during a reproductive cycle. Comp. Biochem. Physiol. 42B:627-636.
230.
Marquardt, R.R. 1971. Multiple molecular forms of avian aldolases. V.
Purification and molecular properties of chicken (Gallus domesticus) liver aldolase.
Can. J. Biochem. 49:647-657.
231.
Marquardt, R.R. 1971. Multiple molecular forms of avian aldolase. VI. Enzymic
properties and amino acid composition of chicken liver aldolase and comparative
immunochemical properties. Can. J. Biochem. 49:658-665.
232.
Yu, J. Y-L., L.D. Campbell and R.R. Marquardt. 1971. Sex hormone control
mechanisms. I. Effect of estrogen and progesterone on major cellular compounds in
chicken (Gallus domesticus) oviducts. Can. J. Biochem. 49: 348-356.
233.
Campbell, L.D., J. Y-L. Yu, S.C. Stothers and R.R. Marquardt. 1971. Sex
hormone control mechanisms. II. Influence of estrogen and progesterone on the
activities of key enzymes involved in carbohydrates metabolism of chicken (Gallus
domesticus) oviducts. Can. J. Biochem. 49:201-206.
234.
Marquardt, R.R. 1970. Multiple molecular forms of avian aldolases. IV.
Purification and Properties of chicken (Gallus domesticus) brain aldolase. Can. J.
Biochem. 48:322-333.
235.
Marquardt, R.R. 1969. Multiple molecular forms of avian aldolases. III. Tissue
distribution and properties of the predominant isozymes from chickens (Gallus
domesticus). Can. J. Biochem. 47:1187-1194.
236.
Marquardt, R.R. 1969. Multiple molecular forms of avian aldolases. II.
Enzymatic properties and amino acid composition of chicken (Gallus domesticus)
breast muscle aldolase. Can. J. Biochem. 47:527-534.
220.
21
Marquardt, R.R. 1969. Multiple molecular forms of avian aldolases. I.
Crystallization and physical properties of chicken (Gallus domesticus breast muscle
aldolase. Can. J. Biochem. 47:517-527.
238.
Marquardt, R.R., C.W. Carlson and R.W. Brosemer. 1968. Glyceraldehydephosphate dehydrogenase: Crystallization from honey bees; quantitative
immunochemical and electrophretic comparison of the enzyme in other insects. J.
Insect. Physiol. 14:317-333.
239.
Brosemer, R.W. and R.R. Marquardt. 1966. Insect glycerolphosphate
dehydrogenase. II. Enzymic properties and amino acid composition of the enzyme
from bee thoraces. Biochem. Biophys. Acta. 128:464-473.
240.
Marquardt, R.R. and R.W. Brosemer. 1966. Insect glycerolphosphate
dehydrogenase. I. Crystallization and physical properties of the enzyme from bee
thoraces. Biochem. Biophys. Acta. 128:454-463.
241.
Marquardt, R.R., T.L. Forster, G.R. Spencer and G.H. Stabenfeldt. 1966. Aesterase activities of milk from cows with experimentally induced mastitis. J. Dairy
Sci. 49:631-634.
242.
Marquardt, R.R. and T.L. Forster. 1966. Variations in bovine plasma Aesterase activity and the relationship between plasma and milk A-esterase activities.
J. Dairy Sci. 49:19-23.
243.
Marquardt, R.R. and T.L. Forster. 1965. A titrimetric procedure for the assay
of milk arylesterase activity. J. Dairy Sci. 48:1602-1606.
244.
Marquardt, R.R. and T.L. Forster. 1965. Milk-esterase levels as influenced by
stage of lactation. J. Dairy Sci. 48:1526-1528.
245.
Marquardt, R.R. and K.M. Asplund. 1964. The effects of variations in volume
of inocula on the in vitro cellulose digestion by rumen micro-organism supported by
nutritionally inadequate media. Can. J. Anim. Sci. 44:24-28.
246.
Marquardt, R.R. and J.M. Asplund. 1964. The effects of water extracts of
forages on in vitro cellulose digestion by rumen microorganisms. Can. J. Anim. Sci.
44:16-23.
237.
Proceedings (Total = 64)
1. Marquardt, R.R. 2011. Epidermal growth factor (EGF) and therapeutic antibodies for
pig diets: An alternative approach to the use of antibiotics as growth promotants.
Revista Computadorizada de Produccicon Porcina 18(3):177-180
2. Owusu-Asiedu, A., C.M. Nyachoti, R.R. Marquardt. 2003. Egg yolk antibody, zene
oxide and fumaric acid supplementation provides passive control to Escherichia coli
(K88) infection in early-weaned pigs fed pea proteins isolate-containing diets. Banff
Digestive Physiology of Pigs Symposium, Banff, AB, May 14-16.
3. Brenes, A., A.J. M. Jansman and R.R. Marquardt. Recent progress on research on
the effects of antinutritional factors in legume and oilseeds in monogastric nutrition:
In Recent Advances of Research in Antinutritional Factors in Legume Seeds and
Oilseeds. EAAP Publication No. 110, 2004 Toledo Spain, 8-10 March 2004, pp. 195217.
4. Marquardt, R.R., S. Li and J-W. Kim. 2002. Egg yolk antibodies for wellness. Owen
J. Catterill Egg Science Symposium, 91 Annual Meeting Poultry Sci. Assoc.,
22
University of Delaware, Newark, DE. August 11-14.
5. Marquardt, R.R. and S. Li. 2001. Control of diarrhea in young pigs using therapeutic
antibodies. Proc. Allen D. Leman Swine Conference, Hyatt Regency Hotel,
Minneapolis, MN. September 15-18.
6. Marquardt, R.R., A. Owusu-Asiedu, C.M. Nyachoti and S. Baidoo. 2001. Performance
of young pigs fed diets containing pea protein and egg yolk antibodies. Proc.
Minnesota Nutrition Conference, Hilton, Minneapolis-St. Paul, Airport Bloomington,
MN, September 11-12.
7. Marquardt, R.R. and S. Li. 2000. Therapeutic antibodies in pig diets. Proc. 21 West.
Nut.Conf., The Lombard, Winnipeg, MB, Sept. 28 and 29, pp. 177-194.
8. Guenter, W., Z. Zhang, and R.R. Marquardt, 2000. From hypothesis to practice: Use
of log-linear model to predict and evaluate the response of non-starch
polysaccharide enzymes in poultry feeds. In: Selected Topics in Animal Nutrition,
Biochemistry and Physiology. (Eds.) W. Sauer and J. He. pp 167-194. Dept. Animal
Sci., University of Alberta, Edmonton.
9. Marquardt, R.R. 1999. Control of intestinal diseases in pigs by feeding of specific
chicken egg antibodies. Proceedings Chinese National Annual Meeting of Animal
Physiology and Biochemistry, Huhehaote, Inner Mongolia, Aug. 18-24, 1999.
10. Li, S. R.R. Marquardt and A.A. Frohlich. 1999. Disposition and confirmation of
ochratoxins in rats and biological samples. Proceedings Chinese National Annual
Meeting of Animal Physiology and Biochemistry, Huhehaote, Inner Mongolia, Aug.
18-24, 1999.
11. Marquardt, R.R. 1998. Antibody loaded eggs for piglets: Prevention of mortality in
baby pigs from diarrhea. Proceedings of the Second International Symposium on Egg
Nutrition and Newly Emerging Ova-technologies, April 5-8, Banff, AB.
12. Marquardt, R.R. 1997. Therapeutic antibodies in pig diets. Eighteenth Western
Nutrition Conference, The Lombard, Winnipeg, MB, Sept. 17 and 18.
13. Marquardt, R.R. 1997. The story on egg-yolk antibodies to control baby pig diarrhea.
Manitoba Swine Seminar. International Inn. Winnipeg, MB, January 29-30, pp. 109112.
14. 12. Marquardt, R.R. 1997. Enzyme enhancement of the nutritional value of cereals:
Role of viscous, water-soluble nonstarchy polysaccharides in chick performance.
Proceedings of First Chinese Symposium on Feed Enzymes, Nanjing Agricultural
University, Nanjing, P.R. China, May 6-8, pp. 5-17.
23
15. Marquardt, R.R. and M. Bedford. 1997. Recommendations for future research on the
use of enzymes in animal feeds. Proceedings of First Chinese Symposium on Feed
Enzyme, Nanjing Agricultural University, Nanjing, P.R. China, May 6-8, pp. 129-138.
16. Hoehler, D., R.R. Marquardt and A.A. Frohlich. 1996. Induction of lipid peroxidation
by iron nitrilotriacetate and ochratoxin A in vitro and in vivo. Proceedings on Minerals
and Trace Elements . Friedrich-Schiller-Universität Jena, Germany, pp. 104-111.
17. Nada, S.A., R.R. Marquardt and M. Arbid 1996. Effect of vicine and divicine on
glutathione, hemolysis and mortalities in different sex and age in albino rats.
Proceeding Third Congress of Toxicology in Developing Countries, Cairo, Egypt, pp.
147-152.
18. Gan, Z., R.R. Marquardt, D. Abramson and R. Clear. 1996. The characterization of
chicken antibodies raised against Fusarium spp by ELISA and immunoblotting.
Proceedings of Regional Fusarium/Scab Forum. Holiday Inn South, Winnipeg, MB,
October 29-30, pp. 46-55.
19. Höhler, D., R.R. Marquardt and A.A. Frohlich. 1996. Induction of lipid peroxidation by
iron nitrilotriacetate and ochratoxin A in vitro and in vivo. Proceedings Conference on
Minerals and Trace Elements. Jena, Germany. December 6 and 7, pp. 104-111.
20. Marquardt, R.R. and J. Brufau. 1996. Future of feed enzymes: Orientation and
perspectives. In: Feed Manufacturing in Southern Europe: New Challenges, Vol. 26.
Eds., A. Gendrau and J. Brufau. Reus, Spain, May 9-11, pp. 181-187.
21. Marquardt, R.R. 1994. Enhancement of the nutritive value of cereals (wheat, oats,
barley and rye) and lupins for poultry by the inclusion of enzymes in the inclusion of
enzymes in the diet. Joint Proceedings of the Second International Round table on
Animal Feed Biotechnology. Probiotics and Workshop on Animal Feed Enzymes.
Edited S.K. Ho, D.A. Leger and E.E. Lister. Ottawa, ON. February 3-4, pp. 167-174.
22. Marquardt, R.R. 1994. Use of enzymes to improve nutrient availability in Manitoba
Feeds. Proceedings Fifteenth Western Nutrition Conference, Winnipeg, Manitoba,
September 13 and 14. pp. 153 to 160.
23. Marquardt, R.R. 1994. Reduction of the toxic effects of certain antinutritional factors
in the diet by free-radical scavenging vitamins. Proceedings Dia del Colaborador,
IRTA, Centre de Mas Bove, Reus, Spain, March 15.
24. Marquardt, R.R. 1994. Enhancement of the nutritive value of cereals and lupins for
poultry by the inclusion of enzymes in the diet. Proceedings Dia del Colaborador,
IRTA, Centre de Mas Bove, Reus, Spain, March 15, 1994.
25. Marquardt, R.R. 1994. Use of enzymes to improve nutrient availability in Manitoba
feedstuffs. Proceedings of Fifteenth, Western Nutrition Conference, Winnipeg, MB.,
September 13-14.
24
26. Marquardt, R.R. 1994. Immunoassays for mycotoxins analyses in foods and
agriculture. Presented at the Immunoassay Workshop for Environmental and AgricFood Science. Saint Boniface Research Centre, Winnipeg, MB, April 27-28.
27. Marquardt, R.R. 1993. Use of legume seeds (peas, faba beans, lupins and grass pas)
in poultry diets. Influence of antinutritive factors. Proceedings of Ninth Australian
Poultry and Feed Conference. Invited Presentation October 10-13, Hotel Conrad,
Jupiters Casino, Gold Coast, pp. 47-51.
28. Marquardt, R.R., 1993. Enhancement of the nutritive value of cereals (wheat, oats,
barley and rye) and lupins for poultry by the inclusion of enzymes in the diet.
Proceedings of Ninth Australian Poultry and Feed Conference. Invited Presentation
October 10-13, Hotel Conrad, Jupiters Casino, Gold Coast, pp. 74-79.
29. Marquardt, R.R. 1993. Effects of molds and their toxins on livestock performance: A
Western Canadian perspective. Proceedings Fourteenth Western Nutrition
Conference. Invited Presentation September 16-17, Calgary, AB, pp. 115-129.
30. Kuiper-Goodman, T., K. Ominski, R.R. Marquardt, E. McMullen, S. Malcolm, G.A.
Lombaert and T. Morton. 1993. Estimating human exposure to ochratoxin A in
Canada. Human Ochratoxicosis and its Pathologies, edited by E.E. Creppy, M.
Castegnaro and G. Dirheimer (Collogue INSERM Montrouge, France: John Libbey
Eurotext Ltd.), pp. 167-174.
31. Brenes, A., R.R. Marquardt, W. Guenter and B. Slominski. 1992. Broiler chick
performance, gastrointestinal tract size and digestibility of non-starch
polysaccharides and oligosaccharides as affected by enzyme addition to diets
containing whole and dehulled lupin (L. albus). 1'ere Conference Europeenne Sur Les
Proteagineux, Angers, France, June 1-3, pp. 477-488.
32. Marquardt, R.R., A.A. Frohlich and D. Abramson. 1989. Ochratoxin A. An important
western Canadian storage mycotoxin. Invited paper. Canadian Federation of
Biological Societies meeting. June 13, 1989, University of Calgary.
33. Marquardt, R.R., A.I. Fengler, A.T. Ward, T. Antoniou and R. Miser. 1989. The use of
rye as a feed grain. Sixth International Grains Institute Meeting, Winnipeg, Manitoba,
May 10.
34. Rotter, B.A., R.R. Marquardt and W. Guenter. 1989. Optimising Responses from
Enzymes in Poultry and Pig Diets. New Methods for Ensuring Response. Alltechs 5th
Annual "Biotechnology in the Feed Industry" Symposium. Lexington, Kentucky, April
17-19, 1989.
35. Guenter, W., L.D. Campbell, R.R. Marquardt and B.A. Rotter. 1989. Evaluation of the
nutritive value of barley. Feed and Food Barley Workshop, Holiday inn, Saskatoon,
Saskatchewan, March 23.
25
36. Marquardt, R.R., W. Guenter and B.A. Rotter. 1988. The future of exogenous
enzymes in animal feeds. Manitoba Agri-Forum, Winnipeg, Manitoba, December 1314. pp. 173-177.
37. Marquardt, R.R., A.I. Fengler and J. Pawlik. 1987. Improvement of the nutritional
value of rye and wheat grains through the use of crude enzymes of microbial origin.
Invited paper, Alltech. Third Symposium on Biotechnology of the Feed Industry,
Lexington, Kentucky.
38. Rotter, B.A., R.R. Marquardt, M. Neskar and W. Guenter. 1987. Improvement of the
nutritional value of barley through the use of crude enzymes of microbial origin.
Invited paper, Third Symposium on Biotechnology of the Feed Industry, Lexington,
Kentucky.
39. Marquardt, R.R. and J.M. Bell. 1986. Future potential of pulses for use in animal
feeds. Invited paper, International Food Legume Research Conference on Pea, Lentil,
Faba bean and Chickpea. Spokane, Washington.
40. Rackis, J.J. and R.R. Marquardt. 1986. A review of the nutritional properties, content
and inactivation of trypsin inhibitors in oilseeds, legumes, potatoes and cereals.
Round table presentation, 4th World Congress of Animal Feeding, Madrid, Spain, pp.
305-318.
41. Marquardt, R.R. and A. Fengler. 1985. An improvement of the nutritional value of rye
through the use of fungal enzymes. Proc. 6th West. Nutr. Cong., Winnipeg,
Manitoba. pp. 35-43.
42. Marquardt, R.R. 1983. The significance of antinutritive factors in prairie feedstuffs.
Proc. Fourth Annual Western Nutrition Conference, Saskatoon, Saskatchewan,
September 14-15. pp. 26-42.
43. Marquardt, R.R. 1982. Role of fiber in broiler and layer rations. Minutes of 31st
Annual Meeting of the Expert Committee on Animal Nutrition, Edmonton, Alberta,
June 1-3.
44. Marquardt, R.R. 1981. Favism. Proceedings of International Conference on faba
beans. Cairo, Egypt, March 7-11.
45. Marquardt, R.R. 1981. Update of faba beans and vicine. Minutes of the 30th Annual
Meeting of the Expert Committee on Animal Nutrition, Winnipeg, Manitoba, June 2-4.
46. Marquardt, R.R. 1980. Factors affecting the utilization of rye by chicks. In Proc.
Second International Conference on Rye and Triticale.
26
47. Marquardt, R.R. 1980. Identification of the egg size depressing factor in faba beans.
Twenty-ninth Annual Meeting of the Expert Committee on Animal Nutrition,
Winnipeg, Manitoba, June 3-5.
48. Marquardt, R.R. 1980. Toxic substances in livestock feeds (ergot). Manitoba Animal
Industry Conference Proceedings, December 12. pp. 31-39.
49. Misir, R. and R.R. Marquardt. 1978. Factors affecting rye (Secale cereale L.)
utilization in growing chicks. Proc. Can. Fed. Biol. Soc. 21:180.
50. Marquardt, R.R. 1978. Faba beans and pea proteins as an alternate source of
protein. Twenty-seventh Annual Meeting of the Expert Committee on Animal
Nutrition, Ottawa, Ontario, January 13. pp. 14-15.
51. Marquardt, R.R. 1978. Advanced information. Nutritional quality of faba beans. Proc.
Manitoba Agronomists Conference, Winnipeg, December 12-13.
52. Marquardt, R.R. 1977. Factors affecting faba bean utilization in domestic livestock.
Canada Committee on Plant Science, Winnipeg, February 15.
53. Marquardt, R.R. 1977. Isolation and characterization of growth inhibitors in faba
beans. Canada Committee on Animal Nutrition, Winnipeg, January.
54. Marquardt, R.R. 1976. Progress with faba beans in other provinces. Alberta Pulses
Committee Annual Meeting, Edmonton, December 16.
55. Marquardt, R.R. 1976. Nutritional Properties of Faba beans, Seminar, The University
of Manitoba, June 10.
56. Marquardt, R.R., A.T. Ward, L.D. Campbell and P. Cansfield. 1976. Purification of the
growth inhibitor in faba beans (Vicia faba). In Proc. West. Sec. Amer. Soc. Anim. Sci.
27:138-141.
57. Marquardt, R.R. 1976. Antinutritional factors in the faba bean. In Proc. Can. Comm.
on Anim. Nutr. 25:45-46.
58. Ward, A.T., R.R. Marquardt, L.D. Campbell and P. Cansfield. 1976. Isolation of the
growth depressing factor in faba beans. (Vicia faba). In Proc. Can. Fed. Biol. Soc.
19:5.
59. Marquardt, R.R. 1975. Faba bean utilization by poultry. Proc. Can. Comm. on Anim.
Nutr. 24:70.
60. Marquardt, R.R. 1974. Comparative physical, chemical and enzymatic properties of
the isozymic forms of avian aldolases and fructose diphosphatases. Vol. 11, Proc.
Third International Conf. on Isozymes. pp. 767-783.
27
61. Marquardt, R.R., L.D. Campbell, S.C. Stothers, J.A. McKirdy and D. Waddell. 1974.
Chemical composition of faba beans and effect of methionine supplementation and
autoclaving on the nutritional value of faba beans when fed to chicks and rats. Proc.
First National Faba Bean Conf. 1: 75-95.
62. Yu, J. Y-L and R.R. Marquardt. 1972. Cellular growth patterns of the chicken oviduct.
Proc. (West. Sec.) Amer. Soc. Anim. Sci. 23:275-279.
63. Frohlich, A.A. and R.R. Marquardt. 1972. Hormonal regulation of cyclic AMP levels in
fowl. Proc. (West Sec.) Amer. Soc. Anim. Sci. 23:245-249.
64. Bush, R.S., L.D. Campbell and R.R. Marquardt. 1972. Distribution of mercury within
chicken tissues. Proc. (West Sec.) Amer. Soc. Anim. Sci. 23:571-575.
Books
1. Marquardt, R.R. and Han Z-K (Editors). 1997. Enzymes in Poultry and Swine Nutrition,
IDRC Press, Ottawa, ON, pp. 142. Published in both English and Chinese.
Book Chapters and Reviews (Total = 23)
1.Marquardt, R.R., M.R. Bedford. 2000. Future Horizons. In: Enzymes in Farm Animal
Nutrition (eds M.R. Bedford and G. Partridge), CABI International, Wallingford, Oxon, UK, pp
389-398.
2. Li, S., R.R. Marquardt, D. Abramson. 2000. Immunochemical detection of molds: A
review. J. Food Prot. 63:281-291.
3. Marquardt, R.R. 1998. Control of intestinal diseases in pigs by feeding of specific chicken
egg antibodies. In: Newly Emerging Ova-Biotechnology (ed. J.S. Sim and S. Nakai), CAB
International, Wallingford, Oxon, UK PP. 289-301.
4. Marquardt, R.R., N. Wang, M.S.S. Arbid. 1997. Pyrimidine glycosides, chapter 10. In:
Handbook of Plant and Fungal Toxicants (ed. J.O.F. D'Mello), CRC Press, Inc., Boca Raton,
FL, 33431, U.S.A., pp. 139-155.
5. Marquardt, R.R. 1996. Current and future enzymes in the feed industry. Phytase in
Animal Nutrition and Waste Management (eds M.B. Coelho and E.T. Kornegay). BASF,
Mount Olive, NJ pp. 197-203.
6. Marquardt, R.R. 1996. Effects of molds and their toxins on livestock performance: A
Western Canadian perspective. Animal Feed Sci. Tech. 58:77-89.
7. Marquardt, R.R., A. Brenes, Z. Zhang and D. Boros. 1996. Use of enzymes to improve
nutrient availability in poultry feedstuffs. Animal Feed Sci. Tech. 60:321-330.
28
8. Marquardt, R.R., R. Bird, J. Borsa, G. Johnson, B. McDonald, E.D. Murray and B. Webster.
1994. Food and Feed Safety in Sustainability of Canada's Agri-Food System-A Prairie
Perspective. Editors. J. Elliot, I. Morrison and D. Kraft. Inter. Inst. Sust. Develop., Winnipeg,
MB, Canada.
9. Clarke, J.R., R.R. Marquardt, A.A. Frohlich, A. Oosterveld and F.J. Madrid. 1994. Isolation
and characterization of ochratoxin class specific hen egg yolk polyclonal antibodies. In: Egg
Uses and Processing Technologies: New Developments (ed. J.S. Sim). CAB International,
Wallingford, Oxon, UK., pp. 207-212.
10. Ominski, K.H., R.R. Marquardt, R.N. Sinha and D. Abramson. 1994. Ecological
parameters affecting the growth of storage fungi and the production of associated
mycotoxins. In: Mycotoxin in Grain: Compounds other than aflatoxin. J.D. Miller and H.L.
Trenholm (eds), Egan Press, pp. 287-321.
11. Boros, D. and R.R. Marquardt. 1994. Improvement of nutritional value of rye by enzyme
application Hodowla Roslin Aklimatyzacja I Nasiennictwo, 38:95-110.
12. Marquardt, R.R. and A.A. Frohlich. 1992. A review of recent advances in understanding
ochratoxicosis. J. Anim. Sci. (invited review), 70:3968-3988
13. Frohlich, A.A., R.R. Marquardt and K.H. Ominski. 1991. Ochratoxin A as a contaminant
in the human food chain: A Canadian perspective. In: Mycotoxins, Endemic Nephropathy
and Urinary Tract Tumours (ed. M. Castegnaro, R. Plestina, G. Dirheimer, I.N.
Chernozemsky and H. Bartsch). Inter. Agency for Research in Cancer, Lyon. pp. 139-143.
14. Marquardt, R.R., Frohlich, A.A. and D. Abramson. 1990. Ochratoxin A - An important
western Canadian storage mycotoxin. Can. J. Physiol. Pharmacol. 68:991-999.
15. Marquardt, R.R. 1989. Vicine and Convicine and Their Aglycones - Divicine and
Isouramil. In Vol. II, Toxicants of Plant Origin, (ed. P.R. Cheeke), CRC Press, Inc., Boca
Raton, FL, 33431, U.S.A. pp. 161-200.
16. Marquardt, R.R. 1989. Dietary effects of tannins, vicine and convicine. In: Recent
Advances of Research on Antinutritional Factors in Legume Seeds (eds. J. Huisman, T.F.B.
van der Poel and I.E. Liener). Pudoc, Wageningen, The Netherlands. pp. 141-155.
17. Rotter, B.A., R.R. Marquardt and W. Guenter. 1989. Enzymes in Feed - They Really Can
Be Made To Work. In: Biotechnology in The Feed Industry, (ed. T.P. Lyons). Alltech
Technical Publication, Nicholasville, KY. pp. 149-160.
18. Marquardt, R.R. and J.M. Bell. 1988. Future potential of pulses for use in animal feeds.
In: World Crops: Cool Season Food Legumes (ed. R.J. Summerfield). Martinus Nijhoff/Dr.
W. Junk Publishers, Dordrecht, The Netherlands. pp. 421-444.
19. Marquardt, R.R., A.I. Fengler, and J. Pawlik. 1987. Improvement of the nutritional value
of rye and wheat grains through the use of crude enzymes of microbial origin. In T.P. Lyons
edition of Biotechnology in The Feed Industry, Alltech Technical Publications, Nicholasville,
KY. pp. 241-250.
20. Rotter, B.A., R.R. Marquardt, M. Neskar and W. Guenter. 1987. Improvement of the
nutritional value of barley grains through the use of crude enzymes of microbial origin. In
29
T.P. Lyons edition of Biotechnology in the Feed Industry, Alltech Technical Publications,
Nicholasville, KY. pp. 251-256.
21. Rackis, J.J. and R.R. Marquardt. 1986. A review of the nutritional properties, content
and inactivation of trypsin inhibitors in oilseeds, legumes, potatoes and cereals. pp. 305317. In: 4th World Congress of Animal Feeding edition, Garsi, Londres 17-28028, Madrid,
Spain.
22. Marquardt, R.R. 1982. Favism. pp. 343-354 in G. Hawtin and C. Webb, ed. Faba Bean
Improvement, Martinus Nijhoff Publishers, P.O. Box 566, 2401 CN The Hague, The
Netherlands.
23. Marquardt, R.R. 1983. Antimetabolites in faba beans: Their metabolic significance. Fabis
7:1-4.
Abstracts: (Total = 28)
1. Owusu-Asiedu, A., R.R. Marquardt, C.M. Nyachoti and S.K. Baidoo. 2001. Response of
early weaned pigs to pea protein isolate-based diets supplemented with chicken egg-yolk
anti-E. coli (K88) antibody. J. Animal Sci., Supplement 1; pp 21.
2. Cole, S. and R. R. Marquardt. 2001. Testing for the presence of enterotoxigenic
Esherichia coli inflictions causing diarrhea in swine using PCR and ELISA techniques. Inter
Anim. Agric. Food Sci. Conf., July 24-28, Indianapolis, I.N. J. Animal Science, Supplement
1; pp 336.
3. Zhang, Z., R.R. Marquardt and W. Guenter. 2001. Release of water insoluble
arabinoxylans from rye bran by ferulic acid esterase and pancreatin. Inter. Anim. Agric.
Food Sci. Conf. July 24-28, Indianapolis, I.N. J. Animal Science, Supplement 1, pp 406.
4. Cho, S.H., P.L. Loewen and R.R. Marquardt. 2001. Recombinant production of chicken
egg- yolk antibodies against enterotoxigenic Escherichia coli by use of a DNA vaccine. Inter.
Anim. Agric Food Sci. Conf. July 24-28. Indianapolis, I.N. J. Animal Science, Supplement 1,
pp 370.
5. Owusu-Asiedu, A., R.R. Marquardt, S.K. Baidoo, A.A. Frohlich, C.M. Nyachoti and S.K.
Cho. 2000. Spray-dried porcine plasma: a therapeutic antibody against enterotoxigenic E.
coli in early weaned pigs. Agri-Food 2000 Conference, Winnipeg, July 15-18.
6. Jaradat, Z.W. and R.R. Marquardt. 1999. Production and characterization of therapeutic
anti-idiotype antibodies for control of diarrhea caused by Escherichia coli K88. Conference
on Agric. Role Managing Antimicrobial Resistance. Oct. 24-26, Toronto, ON. Canada
7. Zhang, Z., R.R. Marquardt and W. Guenter. 1999. A simple dietary viscosity assay for
evaluating the efficacy of enzyme preparations and predicting the performance of Leghorn
chicks fed rye-based diets. Poultry Sci.
8. Zhang, Z., R.R. Marquardt and W. Guenter. 1999. Prediction of the effect of an enzyme
on chick performance when added to a cereal-based diet: use of a log-linear model
equation. Poultry Sci.
30
9. Jin, L.Z., R.R. Marquardt and S.K. Baidoo. 1999. Inhibitory action of the Lactobacillus
isolates against enterotoxigenic Escherichia coli K88, K99 and 987P is due to organic acids
mainly acetic acid. The 6th conference on Lactic Acid Bacteria: Genetics, Metabolism and
Application: September, The Netherlands.
10. Jin, L.Z.1,2, R.R. Marquardt2, A.A. Frohlich2 and Zhao, X.1 1999. Competitive exclusion
of enterotoxigenic Escherichia coli K88 from small intestinal mucus by a strain of
Enterococcus durans. The 6th conference on Lactic Acid Bacteria: Genetics, Metabolism and
Application. September, The Netherlands.
11. Jaradat, Z.W. and R.R. Marquardt. 1999. Therapeutic anti-idiotypic antibodies to E. coli
K88 as an alternative to antibiotic use in the meat industry. Inter. Assoc. Milk Food Environ.
Sanit. Annual Meeting, Aug. 1-6, Dearborn, MI.
12. Jin, L.Z., R.R. Marquardt, S.K. Baidoo and A.A. Frohlich. 1998. Protective effects against
adhesion of entertoxigenic Escherichia coli to immobilized intestinal mucosal preparations by
egg-yolk antibodies. J. Anim. Sci. 76 (Suppl 1):34.
13. Li, S., R.R. Marquardt and A.A. Frohlich 1998. Confirmation of ochratoxins in tissues:
Formation of methyl esters in presence of acidified methanol. Proceedings AOAC
International Meeting, September 13-17, Montreal. QC.
14. Höhler, D., K-S Südekum, S. Wolfram, A.A. Frohlich and R.R. Marquardt. 1998. Studies
on ochratoxin A in sheep. Proc. Soc. Nutr. Physiol. 7:94.
15. Frohlich, A.A. S. Li and R.R. Marquardt. 1997. Determination of ochratoxin A and its
derivatives in different matrices. Proceedings Midwest AOAC Meeting, June 9-11, Fargo, ND.
16. Kerkadi, A., C. Barriault, A.A. Frohlich, R.R. Marquardt, I.M. Yousef and B. Tuchweber.
1997. Adsorption of ochratoxin A (OA) by cholestyramine may be a mechanism by which
this resin decreases OA plasma levels in rats. Proceedings International Congress of
Nutrition.
17. Höhler, D., A.A. Frohlich, R.R. Marquardt and H. Stelsovsky. 1997. Determination of
tocopherol in serum by high performance liquid chromatography. Proc. Soc. Nutr. Physiol.
6:153.
18. Barriault, C., A. Kerhadi, A.A. Frohlich, R.R. Marquardt, I.M. Yousef and B. Tuchweber.
1996. Effect of dietary cholestyramine on ochratoxin A toxicity in rats. FASEB Abstracts
10:D20.
19. Kim, J.W., R.R. Marquardt, S.K. Baidoo, and A.A. Frohlich. 1996. The use of egg
antibodies to counteract diarrheal diseases in piglets. J. Anim. Sci. 74 (Suppl. 1):195.
20. Li, S. R.R. Marquardt, A.A. Frohlich, T.G. Vitti and G. Crow. 1996. Pharmacokinetics of
ochratoxin A and its metabolities in rats. J. Anim. Sci. 74 (Suppl. 1):210.
21. Vilá, B. and R.R. Marquardt. 1996. Effect of T-2 toxin on in vivo lipid peroxidation and
vitamin E status of mice. FASEB Abstracts 10:B230.
31
22. Hoehler, D., R.R. Marquardt, A.R. McIntosh, M.S. Madhyastha and H. Xiao. 1996. Model
studies on free-radical generation induced by different mycotoxins in yeast and bacteria
FASEB Abstracts 10:A479.
23. Höhler, D., R.R. Marquardt, A.R. McIntosh and H. Xiao. 1996. Free-radical generation as
induced by ochratoxin A and its analogs in bacteria (Bacillus brevis). Proc. Soc. Nutr.
Physiol. 5:64.
24. Höhler, D. and R.R. Marquardt. 1996. Interactions of mycotoxins ochratoxin A and T-2
toxin with dietary antioxidants in chickens. Proc. Soc. Nutr. Physiol. 5:74.
25. Marquardt, R.R., Z. Zhang, G. Wang and G.H. Crow. 1996. A simple model for
predicting the response of chickens to dietary enzyme supplementation. Proc. Soc. Nutr.
Physiol. 5:23.
26. Clarke, J.R., A.A. Frohlich, R.R. Marquardt and H. Xiao. 1995. Simple techniques for the
extraction, quantification and confirmation of ochratoxin in swine kidney. AOAC
International Meeting, Sept. 17-21. Nashville Tennessee, p. 76.
27. Hoehler, D., R.R. Marquardt, M.S. Madhyastha and A.R. McIntosh. 1995. Free-radical
medicated lipid peroxidation induced by T-2 toxin in yeast. J. Animal Sci. J. Anim. Sci. 73
(Suppl. 1):394.
28. Wang, G.J., R.R. Marquardt and W. Guenter. 1995. Effects of irrodiation and enzyme
supplementation of rice bran (Singapore) on the performance of Leghorn chickens. Poultry
Sci. 74 (Suppl. 1):126.
32