new avenues for selective heating of organic reactions

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NEW AVENUES FOR SELECTIVE HEATING OF ORGANIC REACTIONS

Gregory B. Dudley

Associate Professor of Chemistry and Biochemistry

Florida State University, Tallahassee, FL 32306-4390

Research in the Dudley Lab is designed to further the science and practice of organic chemistry. This seminar will focus on the use of microwave electromagnetic radiation to produce the thermal energy needed to promote synthetic organic reactions. Organic reaction mixtures have been heated convectively since the dawn of the science, and the physics of convective heat transfer underlies all of physical organic theory. Microwave energy, in contrast, produces heat by fundamentally different physical mechanisms, which need to be understood in order for us to gain maximum benefit from this new technology.

On behalf of our collaborative team at FSU, I will describe a physical model for selective heating in homogeneous solution and reaction systems in which microwave-specific rate enhancements have been documented both qualitatively and quantitatively.

Recent relevant papers:

(59) Chen, P.-K.; Rosana, M. R.; Dudley, G. B.; Stiegman, A. E. Parameters affecting the microwave-specific acceleration of a chemical reaction. J. Org. Chem. 2014 , 79 , 7425–7436. http://pubs.acs.org/doi/abs/10.1021/jo5011526

Featured in Chemical and Engineering News 2014 , 92 (32), 23. http://cen.acs.org/articles/92/i32/Microwaves.html

(58) Rosana, M. R.; Hunt, J.; Ferrari, A.; Southworth, T.; Tao, Y.; Stiegman, A. E.; Dudley, G.

B. Microwave-Specific Acceleration of a Friedel–Crafts Reaction: Evidence for Selective

Heating in Homogeneous Solution. J. Org. Chem. 2014 , 79 , 7437–7450. http://pubs.acs.org/doi/abs/10.1021/jo501153r

Featured in Chemical and Engineering News 2014 , 92 (32), 23. http://cen.acs.org/articles/92/i32/Microwaves.html

GEOSET < http://www.geoset.info/ > video presentations on selective microwave heating: http://goo.gl/jVhVSC , http://goo.gl/nbECVu , http://goo.gl/o3qN3U , http://goo.gl/OdXeY0

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