LS Chapter 5: Genetics and Heredity • Genetics and Heredity • _____________________ • • • The passing of traits from parents to offspring _____________________ • • The study of how traits pass through generations _____________________ • The _____________________ • 1800’s (so much biology in the 1800’s!) • Austrian (NOT AUSTRALIAN) monk • Worked in the monastery garden • Background in math and science Mendel’s Experiment • Used _____________________ • Controlled the way that the pollinated (reproduced) • Mated plants for a certain trait until they were _____________________ (a.k.a. _____________________) • • True-breeding organisms __________________________________________ He then mated 2 of the true-breeding plants together to form _____________________ • Hybrids are __________________________________________ • • Example: Purple and white plant mated together, the offspring are hybrids Mendel’s First Generation • Mendel _____________________ plants together • Each was true-breeding for 1 form of a certain trait • • Name: ______________________________ Example: True-breeding _____________________x true-breeding _____________________ • All of the offspring are considered to be _____________________ • All of them were _____________________ • Mendel hypothesized that the __________________________________________ Mendel’s Second Generation • Mendel then took 2 of the offspring (_____________________) and _____________________ • For every _____________________ plants, there was _____________________one (_____________) • The _____________________ • The same thing happened whenever he mated 2 of the hybrids together • Not only that, it happened whatever trait he tried (height, seed shape, etc.) • Mendel’s Conclusions • From the experiment, Mendel concluded that __________________________________________ • He called the trait that covered the other up the _____________________ • He called the trait that was covered up by the dominant on the _____________________ • Correcting misconception: The dominant trait is not better, nor is it necessarily more common • • All “dominant” means is that it can cover up the recessive trait Genes and Alleles • While __________________________________________, he correctly guessed that something would be found to explain inheritance • A __________________________________________ • • The different forms of a trait (ex. purple and white) are controlled by different forms of a single gene, called alleles • • Ex. Gene for flower color Example: Gene for flower color has alleles for purple and white __________________________________________and __________________________________________ • We symbolize the _____________________and the _________________________________________ • • • Example: Dominant: _____________________; Recessive: _____________________ The _____________________Dominance and recessiveness are indicated by capital and lowercase. Practice: Dominant or Recessive • Are the following dominant or recessive? • A-_____________________ • b-_____________________ • C-_____________________ • D-_____________________ • e-_____________________ • A note on the letters: Exaggerate if the capital and lowercase look similar! • Inheritance of alleles • Zz You have __________________________________________in each body cell • During _____________________, the chromosomes are sorted into _____________________, each with __________________________________________as body cells • When sperm and egg come together (______________), you get 23 chromosomes from mom and 23 from dad • This means that, for each trait, _____________________ • The _____________________ _____________________ (segments of DNA) for traits • They _____________________though • • Genotype and Phenotype • _____________________=the genes (_____________________) that an organism has • • • Example: __________________________________________ Think _____________________, _____________________ Practice: Genotype/Phenotype • • Example: _____________________ _____________________=The expression of the genotype (i.e. the _____________________of the organism) • • You can get an allele for blue eyes from your mom and brown eyes from your dad Indicate whether the follow show a genotype or a phenotype: • AA-_____________________ • Blue-_____________________ • Aa-_____________________ • Bb-_____________________ • Tall-_____________________ Homozygous vs. Heterozygous • Because we inherit 2 alleles that may be either dominant or recessive, there are 3 combinations that they can take • Dominant-Dominant (_____________________) • • Dominant-Recessive (a.k.a. _____________________) • • “Homo” means “same” When they have __________________________________________, we call them _____________________ • • Ex. aa When an organism has _______________________________for a trait, we call them _____________________ • • Ex. Aa Recessive-Recessive (_____________________) • • Ex: AA “Hetero” means “different” We combine the term “homozygous” with whether it is dominant or recessive • AA=__________________________________________ • aa=__________________________________________ • Heterozygous is only one dominant and one recessive • Aa=_____________________ • aA=_____________________ • • ____________________________________________________________________________________ • • Indicate whether the following are homozygous dominant, homozygous recessive, or heterozygous • SS-_____________________ • Nn-_____________________ • uu-_____________________ • mM-_____________________ Genotype/Phenotype, Homozygous/Heterozygous, Dominant/Recessive • • If there is ___________________________________, they will express the _____________________ Practice: Homozygous vs. Heterozygous • • Blue eyes (b) are recessive to brown eyes (B). With that in mind answer these questions: • If a person has a genotype of Bb, what color eyes do they have? • A person has blue eyes (phenotype). What is their genotype? • A person is homozygous dominant for eye color. What is their genotype? What is their phenotype? Predicting Offspring Traits • There is no way to know for certain what offspring will look like. • • However, we can get a _____________________of what traits they may get. _____________________ • A __________________________________________of offspring inheriting a certain trait. • Shows _______________________________________________________________ • Note that it shows __________________________________________ • • Note: Usually we’d flip this so the capital is in front because it is dominant Thought Experiment: Coin flip • If I flip a coin what is the percent chance it will be heads? • If it comes up heads, what is the chance that the next flip will also be heads? • If it comes up heads 100 times in a row, what is the chance that the 101st flip will also be heads? Using probability in genetics • If a couple is having a child, what is the chance that it will be a boy? • If a couple has 3 boys, what is the chance that their next child will be a girl? • If there is a 50% chance of a child inheriting a genetic disorder and the couple has 1 healthy child, what is the probability their next child will have the disorder? • How to make a Punnett Square • DRAW IT HERE: Because there are 2 alleles for each trait for each parent, we will draw a grid that is 2x2 • We will then put one parent’s alleles on the top • It does not matter which parent (at least to me…) • We will then put the other parent’s alleles on the left side • These correspond to the possibilities of the sperm and eggs • Then, bring the ones on top down each column and the ones on the left across each row • Example • • Another Example • • A person with genotype Gg and a person with genotype GG mate. What are the possible genotypes of the children? Brown hair is dominant to blonde hair. If a man heterozygous for brown hair (Bb) has a child with a blonde woman (bb), what is the chance that the child will have blonde hair? One more Example • Brown eyes are dominant to blue eyes. A man and woman, each heterozygous for brown eyes, are expecting a child. What is the probability that the child will have brown eyes? What about blue eyes? • You Try It • Free earlobes are dominant to attached earlobes. Harry, who is homozygous dominant for earlobes, has a child with Ginny who is homozygous recessive for her earlobes. Answer the following questions: • What is Harry’s genotype? • What is Harry’s phenotype? • What is Ginny’s genotype? • What is Ginny’s phenotype? • What is/are the possible genotype(s) and phenotype(s) that their children could have? • Show your Punnett Square Below: