SOUTH EAST THAMES SOCIETY OF ANAESTHETISTS SETSA MEETING Promoting Anaesthesia in South East England Hosted by DARENT VALLEY HOSPITAL, DARTFORD 9th October 2013 Organising Chairman: Dr Raman Madan SETSA Secretary: Dr Cheng Ong SETSA President: Dr Caroline Thompsett Page 1 of 49 South East Thames Society of Anaesthetists Meeting Organised by Darent Valley Hospital, Dartford Venue: Hilton Dartford Bridge Hotel, DA2 6QF Wednesday 9th October 2013 PROGRAMME 8.30-9.00 8.30-9.00 Set up -Trade Stands SETSA Council Meeting 9.00--9.30 Registration and Coffee 9.30-9.45 Welcome Address Dr R Madan, Meeting Organiser Dr Caroline Thompsett, SETSA President SESSION ONE CHAIRPERSON TBD 9.45-10.15 The Cardiologist and The Anaesthetist in The Heart Centre Dr Ed Petzer, Consultant Cardiologist Dr M Satisha, Consultant Anaesthetist 10.15-10.45 Laser Surgery for Renal Stones and Anaesthetic implications Mr. S. Sriprasad Consultant Urologist Dr. Anu Relwani Consultant Anaesthetist COFFEE SESSION TWO 11.15-12.45 12.45-13.00 CHAIRPERSON Dr V Prasad Trainee Presentations Prize Quiz Dr R Madan LUNCH SESSION THREE CHAIRPERSON Dr Mike Protopapas 14.00 -14.30 Microbes and the Anaesthetist Dr A Gonzalez Consultant Microbiologist 14.30 -15.00 Ultrasound for the Anaesthetist Dr Richard Beese, Consultant Radiologist 15.00-15.30 Acute Kidney Injury in The ITU and Anaesthesia for Renal Disease Dr M Javaid Consultant Nephrologist Dr T Kaz Consultant Anaesthetist COFFEE SESSION FOUR CHAIRPERSON Dr Raman Madan 15.50-16.10 Maternal Sepsis Dr F Iossifidis. Consultant Anaesthetist 16.10-16.30 Critical Care Update Dr M Sange Consultant Anaesthetist 16.30 – Presentation of Prizes Page 2 of 49 AN AUDIT ON VTE PROPHYLAXIS DURING PREGNANCY AND THE PUERPURIUM Dr A. Perham, Dr S. Wade, Dr D. Moor and Dr J. Short Queen Elizabeth Hospital, Woolwich, South London Healthcare Trust, UK Introduction Venous thromboembolism (VTE) remains the 3rd leading cause of direct maternal death in the UK [1]. The most recent triennium saw a significant reduction in mortality caused by VTE, which is possibly attributed to the impact of the RCOG green top guideline (no.37a). 80% of fatal pulmonary embolism in 2003-2005 had identifiable risk factors [2], and NICE estimates that prophylactic low molecular weight heparin (LMWH) reduces risk by 60-70% [3]. Aims 1. To audit the compliance of VTE prophylaxis management on labour ward with the RCOG ‘green top’ guidelines 2. To educate the multidisciplinary team on these guidelines and where necessary, implement changes to improve compliance. Standards All women should have a completed VTE risk assessment before delivery All women scoring 2 or more on the risk assessment should receive LWMH All women with scoring 3 or more should receive LWMH plus TEDS LMWH showed be dosed correctly for all women LMWH is given at least 4 hours after spinal anaesthesia or removal of epidural catheter in all cases Methods Details for patients receiving anaesthetic intervention were recorded, and their notes were then prospectively audited using a specifically designed proforma. 93 sets of notes were audited in January and February 2013. Results of first round 55 patients (59.1%) had a documented VTE risk assessment. Overall, 68 patients (73.1%) received the correct management for VTE prophylaxis. 9 (9.6%) had LMWH prescribed but it was not administered. 68% of patients receiving LMWH were administered the correct dose. All patients had LMWH administered at least 4 hours after regional anaesthesia. However, 24.5% did not receive the dose for over 14 hours post regional anaesthetic. Action taken The results were presented to obstetricians, midwives and anaesthetists at a joint clinical governance meeting. The presentation involved education on the current RCOG & NICE guidelines. The green top guidelines were also integrated into the new Obstetric Anaesthesia guidelines for the hospital, which were distributed to the multidisciplinary team. An alert sticker was placed on the follow up folders as a reminder to check VTE prophylaxis as part of the postnatal follow up round. It was recommended to the maternity department that a standardized VTE risk assessment form rather than multiple forms for different personnel would lead to improved compliance and less confusion. A re-audit is planned for February 2014. Page 3 of 49 References: 1. Centre for Maternal and Child Enquiries (CMACE). Saving Mothers’ Lives: reviewing maternal deaths to make motherhood safer: 2006–08. The Eighth Report on Confidential Enquiries into Maternal Deaths in the United Kingdom. BJOG 2011; 118(Suppl. 1):1–203. 2. Reducing the Risk of Thrombosis and Embolism during Pregnancy and the Puerperium, green top guideline no. 37a, RCOG, Nov 2009 3. Venous Thromboembolism: Reducing the Risk of Venous Thromboembolism in patients admitted to hospital, NICE Clinical Guideline 2010 Page 4 of 49 ANTIBIOTIC PROPHYLAXIS IN NEUROSURGERY - IMPROVING COMPLIANCE Dr Pele Banugo, Dr Harpreet Sodhi, Dr Ben Thorpe, Dr Divna Batas, Dr Katy Laver, Dr Gowri De Zylva King’s College Hospital, London Aim: To assess compliance with local antibiotic prophylaxis guidelines and surgical site infection (SSI) rate within a major London Neurosurgical unit, and subsequent influence of targeted education on these endpoints. Methods: SSIs are amongst the commonest healthcare associated infections (incidence 520%).1 Prophylactic antibiotics, appropriately timed and dosed, and chosen to take into account local resistance patterns, play an integral role in reducing the risk of SSI.2 Phase 1: data proforma used to audit antibiotic administration by anaesthetists (choice, dose and timing). Phase 2: survey of anaesthetists and neurosurgeons to assess awareness of existing antibiotic guidelines. Phase 3: first re-audit to evaluate educational value of phase 2. Phase 4: 12-month period of targeted education e.g. WHO checklist, laminated guidelines, trainee induction. Phase 5: second re-audit (retrospective and prospective limbs) to evaluate efficacy of phase 4. Results: Phase 1 (initial audit): 62 cases evaluated. Correct antibiotic used in 40% of cases. Eight percent of patients developed a surgical site infection. Phase 2 (survey): 17 respondents. Only 18% fully aware of guidelines. Phase 3 (1st re-audit): 40 cases. Correct antibiotics: 90%. SSI rate: 0% Chart 1. Results summary showing compliance and SSI rates for different phases of the audit. Phase 4 (2nd re-audit): retrospective limb: 40 cases. Correct antibiotics and timing: 80% and 68%, respectively. SSI rate: 7.5%. Prospective limb: 24 cases. Correct antibiotics and timing: 96% and 62%. SSI rate: 0%. Conclusions: Compliance with local antibiotic guidelines and, in turn, reduction of SSIs, can be improved through education and audit, and maintained through periodic reinforcement. The anaesthetist’s role is paramount in achieving these endpoints. References: 1. Gifford C, Christelis N, Cheng A. Preventing post-operative infection: the anaesthetist role. Continuing Education in Anaesthesia, Critical Care & Pain. Volume 11, number 5, October 2011. 2. NICE. Prevention and treatment of surgical site infection. Clinical Guideline 74, 2008. Page 5 of 49 HOW LOW DO WE FLOW? A. Mussad and M. Puchakayala, asyamussad@doctors.org.uk Guys and St Thomas’ Hospital, London, SE9 1RT, UK In a trust where over 50,000 patients are anaesthetised a year the cost of volatile anaesthetic agents constitutes a significant proportion of the trust’s expenditure. Our perception was that in our department there is a trend towards the use of moderate to high fresh gas flow rates. As cost reduction in hospitals is a major objective, we conducted an analysis of individual theatre performance auditing the total FGF rates, choice of anaesthetic agents and their consumption. The aim was to feedback the results and reassess the usage of volatile agents following change in practice as a means of improving our performance. Methods Data from 129 anaesthetised cases was collected from the Dräger Primus anaesthetic machine at Guy’s Hospital during November 2012 and February 2013. The following data was recorded: the duration of anaesthetic, the flow rates of oxygen, air and nitrous oxide and the volatile agent used with its consumption and uptake. Data was collected from fourteen operating theatres with their corresponding anaesthetic rooms. Cost expenditure on volatile agents was obtained from the pharmacy department. Results Sevoflurane was the most popular volatile agent used during induction and maintenance of anaesthesia and was used in 77% of cases compared to usage of Desflurane in 10% and Isoflurane in 11%. Volatile anaesthetic agent consumption was noted to be highest in the maxilla-facial, emergency, renal, dental and orthopaedic theatres. This was demonstrated by a high volatile ratio indicating use of high FGF in these theatres. The average VR for all agents was 3.6 (VR range of 1.217.8). The average VR for Sevoflurane and Desflurane were 3.9 and 2.4 respectively. The time taken for the MAC to fall to a value <0.6 or to decrease by more than 30% was on average 7.9 minutes. This duration was noted to be 8.2 minutes where Desflurane was used as compared to 7.8 minutes with Sevoflurane. The trend of expenditure on volatile agents over the last 6 years demonstrated a continuous gradual rise in the consumption of volatile agents. Discussion Utilizing a Volatile Ratio allows assessment of the anaesthetist’s efficiency on a case by case basis. In addition it allows comparison of performance between various theatres based on the surgical speciality. The great variation in efficiency in our study, as measured by the Volatile Ratio, could be partly attributed to differing case mixture between theatres, which included dental theatres where gas induction is commonly used. The high number of VR obtained can also be due to the common practice of employing higher FGF than necessary via semi-closed circle breathing systems despite the availability of validated and optimal initial flow and vaporiser setting regimens as set by manufacturer1,2,3. As such, inclusion of the data from the anaesthetic rooms may have led to falsely high figures. Page 6 of 49 In theatres where lower FGFs were utilised notably a lower VR was obtained when compared to theatres with a higher average FGF. The time to “low-mac”, defined as the time between switching off a volatile agent to the mac value falling to 80% of the previous, was higher with Sevoflurane than Desflurane in contrast to their known pharmacological profiles. The lack of enthusiasm to the use of low FGF has been affected by technical issues, which are now largely historical. With the advance in technology, machines with highly sensitive systems allow accurate use of lower FGF. As such, implementing change in our practice can lead to a significant reduction in the expenditure of volatile agents. Recommendations 1. Utilising a logbook on the anaesthetic machine for each individual anaesthetist as a reflection of their practice and expenditure. This would be valuable in determining an operator’s efficiency aiding to improved practice by use of lower fresh gas flow and subsequently reduction in costs. 2. The use of low fresh gas flows aiming for a Volatile ratio of <3. In the next phase of the audit, we will aim to feed back the data on individual performance against departmental standards. In conclusion, collective change in practice can lead to significant reduction in volatile drug cost so that we able to maintain a complement of wide range of volatile agent availability. References 1. How low can you flow? Dräger 2011. 2. Mapleson WW. The theoretical ideal fresh-gas flow sequence at the start of low-flow anaesthesia. Anaesthesia 1998; 53: 264–72. 3. erou JG, Verheijen R, Booij LH. Model-based administration of inhalation anaesthesia. 4. Applying the system model. British Journal of Anaesthesia 2002; 88: 175– 83. Page 7 of 49 AUDIT OF THE DIFFICULT AIRWAY SOCIETY EXTUBATION GUIDELINES IN A LONDON TEACHING HOSPITAL R. Krol ST4 Background In 2011 the Difficult Airway Society (DAS) produced their extubation guidelines. During the anaesthetic novice period training is focused on intubation rather than extubation. Airway complications during extubation are three times more frequent than those occurring during intubation (12.6 % verses 4.5%). The Anaesthetic Incidents Monitoring Society has estimated that 1% of patients require an intervention on extubation over and above supplemental oxygen. These findings have been confirmed by the Royal College of Anaesthetist’s National Audit Project 4 in which 38 per cent of complications were related to extubation alone, including two deaths. Aim To survey the awareness of the DAS extubation guidelines amongst the consultants of Kings College Hospital (KCH), London and to audit their extubation practice against the DAS guidelines. Method Forty consultants at KCH were asked to describe their extubation practice for a fit and well patient with no airway concerns. Their responses were compared to the DAS extubation guidelines. Results Ninety per cent of consultants were unaware of the DAS extubation guidelines. Only fifty per cent of consultants would routinely use neuromuscular reversal and only thirty per cent would use train of four to assess neuromuscular recovery. Fifty per cent routinely use a positive pressure breath on extubation and only thirty per cent would wait until a patient could obey commands to extubate them. Conclusion The DAS extubation guidelines are poorly adhered to at KCH. Most consultants were unaware of their presence. In order to address this, a poster presenting the extubation guidelines is planned with multidisciplinary teaching of novice anaesthetists and recovery staff. The local extubation complications should be audited. Reference Karmarker S, Varshney S, Trachel Extubation, Continuing Education in Anaesthesia, 8 (6), 2008 Page 8 of 49 SURVEY OF GLIDESCOPE USE IN A LONDON TEACHING HOSPITAL R. Krol ST4 Background Airway complications are a leading cause of anaesthetic morbidity and mortality according to UK defence societies and the ASA closed claims data. The Royal College of Anaesthetists National Audit Project 4 concluded that airway problems arose when difficult intubation was managed by multiple repeat attempts at intubation, stating that it is well recognised that a change of approach is required rather than repeated use of a technique that has already failed. A device such as a glidescope may present an alternative approach as per the Difficult Airway Society’s intubation guidelines. Such devices have been shown to improve the Cormack and Lehane grade of intubation. King’s College London has recently invested in ten new glidescope devices across the trust including remote areas. Aim The aim of this project was to survey the current glidescope use across the trust and to increase awareness of their presence and encourage their routine use to avoid airway incidents and improve patient safety. Method All anaesthetists were asked to complete a proforma each time they used the glidescope, describing their location and the use of the glidescope and whether it had helped with successful airway management between March to June 2013. Results Twenty seven surveys were returned from three of the trust’s ten sites. During the period of March to June 2013 the glidescope was used twelve times in an anticipated difficult airway and three times for an unanticipated airway. Many senior anaesthetic trainees and consultants were unaware of the presence of the glidescopes. Many of us were not using them regularly and few of us had had formal training on it. Conclusion Despite King’s College Hospital’s recent investment in ten new glidescopes they are not being routinely used. Teaching and encouragement of glidescope use is taking place. The survey will then be repeated to demonstrate an improvement in the use of the glidescope across the trust. Reference The GlideScope Video Laryngoscope: randomized clinical trial in 200 patients, D. A. Sun, C. B. Warriner*, D. G. Parsons, R. Klein, H. S. Umedaly and M. Moult, BJA 94, 381 Page 9 of 49 IMPROVING EFFICIENCY AND REDUCING COSTS IN ELECTIVE CAESAREAN SECTIONS R Campbell, S Bapat, S Sharafudeen, N Parry, V Skelton, D Abell King’s College Hospital, London Aim In a time of austerity and increasing financial pressures on the NHS, cost saving within the bounds of patient safety is paramount. The National Institute of Clinical Excellence has issued guidelines regarding requirements for preoperative blood testsi; however there has been little guidance on essential postoperative investigations. Therefore we felt it was important to retrospectively analyse data collated during and after elective caesarean sections performed at King’s College Hospital and the practice of postoperative analysis of full blood count. Methods As part of the MASIMO trial, (ethical approval obtained) both pre-operative and postoperative formal laboratory haemaglobin tests and ‘at point of care’ Hemacue tests were performed on patients undergoing elective caesarean sections. Dats was also collected regarding intraoperative blood loss, transfusion requirements, and day 1 formal laboratory haemaglobin tests perfomed. Data was collated and analysed in Microsoft Excel in order to ascertain if guidance could be given on the use of formal laboratory tests post elective caesarean section. Results Estimated Blood Loss <500ml (n=49) Hb Preo p Hemocu e pre-op 12.3 (1.33 ) 12.4 (1.42) Difference between Lab/Haemoc ue EBL/ ml Hb Post op Hemoc ue postop Hb Day 1 11.0 11.1 10.8 (1.1 (1.3 (1.29) 6) 5) Estimated Blood Loss >500ml (n=35) Difference Hb Hb Hemoc Hb Hemocu between EBL/ Preo Post ue post- Day e pre-op Lab/Haemoc ml p op op 1 ue 11.6 844 9.7 9.7 11.8(1.7 9.8 (1.26 0.6 (0.72) (308. (1.2 (1.1 3) (1.04) ) 4) 2) 4) All numbers shown as mean (+/- SD) 0.6 (0.81) 424 (83.6) Difference between Lab/Haemoc ue Number transfus ed 0.4 (0.41) 1 Difference between Lab/Haemoc ue Number transfus ed 0.3 (0.36) 2 Conclusion There was no significant difference between the haemoglobin measured immediately in recovery and on day 1 post elective section. . In otherwise uncomplicated, elective caesarean sections, with minimal postoperative blood loss, it would appear that a further FBC taken on the first postoperative day could be omitted with little clinical significance. The benefits of this could be several fold. Hemacue can be taken from the lower limb while spinal anaesthesia remains effective, thereby avoiding patient discomfort. Delayed discharge while awaiting laboratory blood tests and time taken for phlebotomy, analysis and review could also be reduced; potentially reducing postnatal workload. In addition, each full blood count (FBC) costs approximately £2.78. In our institution there are approximately 500 elective caesarean sections each year, potentially saving £1390/year. If a hemocue (£0.5/cuvette + £390/yr for calibration solution) is taken in recovery and found to be within acceptable limits our data suggests an additional full blood count could be avoided, saving a further Page 10 of 49 £750/year. This data is to be presented to the obstetric audit meeting with a view to developing guidelines regarding the appropriateness of post-operative formal laboratory tests. UNUSUAL PRESENTATION OF PENETRATING CARDIAC TRAUMA V Patle, R Gray, O Boyd. Brighton and Sussex University Hospitals Trust, Brighton. Introduction: A Stab injury to the thorax and upper abdomen may result in serious injuries to vital organs. We present the case of traumatic mitral regurgitation following stab injury to chest, with a self-sealing left ventricular entry wound. Case description: A 53 year old male patient presented following a self-inflicted stab injury in the left sub-costal region. The patient was unwilling to provide any type of detailed history due to personal reasons. He was conscious, alert and haemodynamically stable throughout. Leucocytosis with white cell count of 30000 was noted on initial presentation. CT chest revealed a pericardial effusion (18 mm) and airspace shadowing in both lungs which was reported as possible infection. Transthoracic echocardiography revealed good biventricular function and moderate mitral regurgitation. The mitral regurgitation was thought to be chronic in nature due to the relative haemodynamic stability and small pericardial effusion in the presence of good cardiac contractility. Worsening hypoxia on the cardiac HDU was attributed to community-acquired pneumonia in view of the CT chest findings of airspace shadowing. Two days after the initial presentation the patient had worsening hypoxia and had developed chest radiograph changes compatible with pulmonary oedema, raising the suspicion of the mitral regurgitation resulting from the recent trauma. Pulmonary artery catheter studies were performed urgently to rule out traumatic septal defect. Transoesophageal echocardiography showed torrential mitral regurgitation with a flail anterior mitral leaflet. Urgent cardiac surgery was undertaken. During the inspection of left ventricle, an injury site just lateral to the LAD (not bleeding) was noted. Anterior leaflet of mitral valve appeared prolapsed with torn chordae tendinae. The patient made full recovery following mitral valve replacement. Discussion: Approximately 20% of cardiac injuries have no obvious signs and symptoms of cardiac injuries1. In this case, we believe that the development of mitral regurgitation as a result of penetrating cardiac trauma was masked by the patient’s unwillingness to provide accurate history, CT scans suggestive of chest infection and the relative haemodynamic stability. The entry wound on the left ventricle in this patient is likely to have sealed as a result of the criss-cross arrangement of myocardial fibers thus preventing the formation of pericardial tamponade or massive haemorrhage. Conclusion: A high index of suspicion of cardiac injury should be suspected with all thorax and upper abdomen trauma. This patient demonstrated that despite his normal physiology for 48 hours post injury he had a life threatening cardiac injury. This case also demonstrates the potential delay of diagnosis when the full history of the events preceding admission are not available for clinical correlation. Page 11 of 49 References: Peter. I. et al. 2013. Stab wound of the heart with unusual sequelae. Texas Heart Institute Journal. 40 (3); 353-57 QUALITY OUTCOMES IN RECOVERY AUDIT TOOL J. Gan, E. Dempsey, C. Lanigan University Hospital Lewisham, London. Corresponding author: ganjohan@gmail.com It has become very difficult to measure outcomes in anaesthesia as these are closely linked to other confounding patient and surgical factors. Traditional mortality outcomes are unsatisfactory as these events are very rare in anaesthesia. We studied outcomes in recovery which are patient focused to see if these might be used to indicate quality of anaesthesia. Methods Following local discussion, we set standards for recovery outcomes as follows: <10% of cases with duration in recovery >2hrs; temperature 36-38C [1]; needing rescue anti-emetic or analgesia; SpO2<90%; systolic blood pressure <90 mmHg; & <1% unexpected Level 2/3 admission. Data was extracted using nursing summary ward chart. The first audit loop was completed in May 2013 and following a feedback session with the theatre team, the audit was repeated in July. Results There were 143 patients in the initial audit and 148 patients in the re-audit. Patients’ demographics and surgical case mix were similar in the audit and re-audit. In the initial audit, 97 (68%) patients did not have their temperature recorded. Of those that did, 15 (33%) were recorded as being < 36 o C. One hundred and twelve (76%) patients had their temperature recorded in the re-audit but 45 (40%) patients were still hypothermic. In terms of patient comfort, 29 (20%) vs 35 (24%) patients required rescue analgesia in audit and re-audit respectively. Two (1%) and three (2%) patients needed rescue anti-emetic in the audit and re-audit. The median (range) discharge time from recovery was 71.5 (47-97) minutes in the audit and 65 (40-92) minutes in the re-audit. There was an increase in early discharges (<30 minutes), five (4%) vs 18 (12%) in the re-audit. One hundred and twenty four (88%) patients were discharged from recovery under 2 hours compared to 126 (87%) in the re-audit. For both audits, patients discharged to the Day Surgery ward had the shortest stays in the first stage recovery area. There were no unexpected Level 2/3 referrals in either period. There were no records of significant hypotension in the first audit period although three cases occurred (2%) in the re-audit: while there was one patient with hypoxaemia in each audit period. Discussion The audit criteria were chosen as they reflect morbidity, contribute to patient satisfaction, and can be directly influenced by the conduct of anaesthesia. The most striking finding was that having set standards, compliance with temperature monitoring improved markedly after the feedback process. This may represent increased staff ‘buy in’ to ensure that standards are met after the group feedback. Delayed discharges from recovery were postulated to indicate patient complications and theatre / ward inefficiency. Despite an increase in caseload, there was a quicker median discharge time in the re-audit period. We found that re-auditing and providing feedback to the theatre team motivated them to improve their performance. It opened channels of communication which allowed processes to be streamlined and problems identified early. We aim to refine this audit tool so that it can be used to Page 12 of 49 monitor our performance and identify reasons for late discharges through root cause analysis. Acknowledgements L.Ramsey-Powell & T. Emmanuel who led the recovery nurses. Reference 1. NICE Guidelines CG65 Inadvertent perioperative hypothermia: The management of inadvertent perioperative hypothermia in adults http://publications.nice.org.uk/inadvertent-perioperative-hypothermia-cg65 Page 13 of 49 ABSTRACT: AUDIT OF QUALITY OUTCOME MEASURES IN ANAESTHESIA Dr Smitha Honnesh, Dr Manisha Shah, Dr Kirti Mukherjee Background/Rationale: • • • • • • To evaluate the quality of anaesthetic practice and to bench mark our future performance using following quality indicators in Postoperative recovery room. (a) Highest pain score (score 0-10) (b)Incidence of nausea and vomiting (c)Maintaining normothermia To feedback the information from these quality indicators Ultimate aim is to improve patient outcomes and safety. Audit criteria & Guidelines: There are no set standards or guidelines This is a pilot audit to bench mark our practice Method: • Prospective audit of 490 patients over a period of 1 month • All theatre cases requiring Anaesthesia excluding pain blocks. • Cases performed in Main theatres and Day Surgery Unit. Key results: 17.7 % of our patients had a pain score of > 5 Majority of these cases were minor or intermediate Surgery and these predominantly were arthroscopies & Gynaecological Surgeries. 49.9 % of our patients were hypothermic on arrival into recovery. It is a huge problem. 9.14% of our patients had nausea and 1.91 % had vomiting. Recommendations: It is a pilot audit to bench marks our practice. We should strive to improve on all quality measures Attention to Pain Management particularly in minor and intermediate operations. Maintaining Normothermia - Keeping them warm prior to and during Anaesthetic - Consider Inditherm warming mattress References: Ref(1) Using quality indicators in anaesthesia: feeding back data to improve care-BJA 109(1):80-91(2012) Ref(2) Clinical outcome data, comparative performance reports and revalidation- A department initiative- RCOA Bulletin 73/May 2012 Page 14 of 49 AN EXPERIENCE OF ANAESTHESIA IN HAWASSA, ETHIOPIA, THE CHALLENGES, TRIUMPHS AND HOPE FOR THE FUTURE Dr Shaima Elnour BSc MBChB FRCA Background: Ethiopia is one of Africa’s poorest states, with 31 percent of its population of 90 million earning less than $1 per day.1 Due to the prohibitive costs of healthcare and rural distribution of the population, coupled with poor transport to access major cities where all secondary and tertiary level care is provided, patients presented very late in the course of their illness. This consequently translates to a wide range of pathology that would rarely be seen in the UK. Lack of investment in healthcare has resulted in weak health care systems and infrastructure. Almost 80 percent of morbidity in Ethiopia is due to preventable communicable and nutritional diseases, both of which are associated with low socio-economic development.2 Method: I spent 5 months in Hawassa, Ethiopia working in the Referral Hospital (HRH) which provided care for a catchment area covering 12 million people. During this time as the only medically qualified anaesthetist, I worked in theatres alongside the anaesthetic practitioners, supervising their practice and teaching. I was charged with writing a curriculum for an anaesthesia Bachelor of Science (BSc) programme to be taught at the university as well as teaching medical students. Time spent outside of these activities was dedicated to establishing a critical care unit in HRH. I wrote guidelines, secured grants for staff training, wrote and taught an introductory course to critical care and set up the unit with funding from the Regional Health Bureau. Results: I have no statistical evidence to demonstrate whether any of the activities that I had undertaken have actually improved patient care but I hope they have. There is now an eight-bedded critical care unit at HRH. The Ministry of Education has approved the anaesthesia BSc curriculum and the University Board is in the process of recruiting teaching staff to deliver the course. On a personal development level, I have been exposed to a wealth of clinical experiences that rarely present themselves in Britain and have learned a useful lesson from each and every single one of them. Discussion: During the time that I spent volunteering in Ethiopia, I was faced with some challenges that are commonly found in the developing country setting and were by no means unique to that country. This presentation will outline some of these challenges, some tips which may help any anaesthetist contemplating a similar task to survive the experience, perhaps enjoy it and hopefully do some good in the process. References: 1) UNData Accessed on 6th September 2013 at http://data.un.org/Data.aspx?d=MDG&f=seriesRowID%3A580 2) The Earth Institute at Columbia University. Centre for National Health Development in Ethiopia Accessed on 6th September 2013 at http://cnhde.ei.columbia.edu/healthsystem/ Page 15 of 49 AUDIT ON CXR REPORTING OF NG TUBE PLACEMENT EAST KENT HOSPITALS UNIVERSITY FOUNDATION TRUST (EKHUFT) Dr Sans-Solachi, Dr Hadlow, Dr Kapoor, Dr Strandvik Background and Aims NG tube placement has been in focus recently due to being included in the National Patient Safety Agency (NPSA) list of ‘never events’. The report indicated that there were problems with misinterpretation of CXRs leading to feed being accidentally administered into the lung. This occurred at all times but was particularly a problem ‘out-of-hours’ and was also related to the competence/grade of staff confirming NG positioning. EKHUFT policy states that reporting of NG tube position should be by consultant radiologists only both in and out of hours. This has led to an out-sourcing of reporting out-of-hours (4 Ways Healthcare) and reports are generated online to confirm NG positioning. There are also sporadic reports of delays in treatment and feeding across the hospital as a result of untimely reporting. The purpose of this audit was therefore to assess whether CXRs were being reported in a timely manner and to assess the quality of the reporting both in and out of hours. Methods We undertook a retrospective collection of data in 2 intensive care units in East Kent Hospitals Trust over a 3 month period. Data was anonymised and collected using our on-line system of Patient Centre (CXR ordering service) and PACS (Radiology review system). We looked at the number of individual patients undergoing CXRs as well as whether they were repeated in these patients both in and out-of-hours. We reviewed whether the report was satisfactory i.e. NG in correct position or whether further intervention was required e.g. advance NG tube and repeat CXR. We also reviewed the time taken for the CXR to be performed and how long it subsequently took for the CXR to be reported both by our on-site radiologists and the off-site radiologists and subsequently whether this could have an impact on patient treatment. Results The total number of patients undergoing CXRs across the 2 sites was 99 with a total of 161 CXR being performed on this patient group. In total 123 were satisfactorily reported in terms of NG position. The time taken to report the CXRs in these patients were as follows:- Day Time Hours Out-of-Hours <30 minutes 40.19% 11.86% 30-60 minutes 19.6% 35.59% >60 minutes 40.19% 50.8% Page 16 of 49 Conclusions Despite guidance for time frames for NG reporting, NG tube reporting time was delayed both on site and off site. Particularly of note was more than 50% of reports took more than 1 hour out of hours. This does not include time for CXR to be requested and performed and so can visibly cause a significant delay in patient treatment administration and establishment of feeding and so may have a negative impact on patient care. New ways of NG placement confirmation such as electromagnetic devices may help to minimise patient exposure to irradiation and improve NG confirmation times. In addition to this, it may be viable to consider specialist radiology training for clinicians such as ITU Consultants in our trust to minimise delays in reporting. References National Patient Safety Agency Alert – published March 2011 Page 17 of 49 OBSERVATIONAL STUDY OF TRANSFUSION PRACTICE IN KING’S COLLEGE HOSPITAL CARDIAC THEATRES AND RECOVERY Dr Andreas Zafiropoulos1, Dr Shital Patel2, Dr Saif Baluch3, Dr Desire Onwochei1, Dr Stephen James4, Dr Daniel Krahne4 Specialist trainee anaesthetics and intensive care, King’s College Hospital, London; Specialist trainee anaesthetics, King’s College Hospital, London; 3Specialist trainee intensive care medicine, King’s College Hospital, London; 4Consultant cardiac anaesthetist, King’s College Hospital, London 1 2 Institution: King’s College Hospital NHS Foundation Trust Aim of the study: Cardiac surgery and cardiopulmonary bypass carry a significant risk of blood loss and blood transfusion. Transfusion of blood products itself carries significant risks (infection, transfusion reaction, lung injury and fluid overload)i,i and is associated with increased morbidity, length of stay, higher mortality and overall costs in cardiac surgical patients.i,i Evidence suggests that transfusion guidelines as well as point-ofcare (POC) thromboelastometry may reduce transfusion requirements as well as assist in the decision making process of what and when to transfuse.i There is currently no transfusion guideline in place and there is significant variability in the use of POC techniques and transfusion triggers at our institution. Therefore we sought to investigate transfusion practice in our cardiac theatres and cardiac recovery to assess whether improvements could be made to our practice. We defined a high-risk group as those with a pre-op Hb <12g/dL, use of anti-platelet drug therapy or warfarin within 5 days before surgery, a measured coagulation defect, those having complex surgery and a time on cardiopulmonary bypass of >180min. We looked at transfusion intra-operatively and post-operatively up to 24 hours. Method: We collected data on 100 patients undergoing cardiac surgery at King’s College Hospital cardiac theatres between May and September 2013. 6 patients were excluded due to missing data. Analysis was performed on the remaining 94 patients. Data was collected on pre-operative blood count, clotting parameters, drug therapy, intraoperative haemoglobin levels and blood product administration as well as postoperative blood count, blood loss and blood product administration. POC thromboelastometry was done with TEG® (Haemonetics®, Massachusetts, USA). Intra-operative heamoglobin level and blood gases were analysed with the i-STAT® 1 Analyzer 300 (Abbott, Illinois, USA). Full blood count and coagulation tests were performed in the central laboratories at King’s College Hospital. Results: Of the 94 patients undergoing cardiac surgery, 60 (63.8%) had coronary artery bypass grafting (CABG), 28 (29.8%) valve replacements, 8 (8.5%) CABG & valve replacements and 5 (5.3%) aortic repair. Page 18 of 49 Overall 62 (66.0%) patients received blood products, 43 (45.7%) red blood cell transfusion (RBC), 39 (41.5%) fresh frozen plasma (FFP) and 36 (38.3%) platelets (PLT). 51(54.2%) patients were defined as high-risk and within the first 24 hours, 30 (58.8%) received RBC, 24 (47.1%) received FFP and 23 (45.1%) received PLT. In the low risk group the numbers were 13 (30.2%), 15 (34.9%) and 13 (30.2%) respectively. Of the 62 patients receiving blood products, 20 (32.3%) were transfused intraoperatively, 21 (33.9%) post-operatively and 21 (33.9%) patients received blood products both, intra and post-operatively. A total of 379 units blood products were transfused (119 RBC, 187 FFP and 73 PLT) of which 42 (35.3%) of RBCs, 68 (36.4%) FFP and 37 (50.7%) PLT were transfused intra-operatively with the remainder transfused post-operatively in the cardiac recovery unit. Thromboelastometry was used in 34.0% of patients intra-operatively and 4.3% of patients post-operatively. The transfusion threshold for RBCs appeared to be between 7-9 g/dL intra-operatively and 7-11g/dL post-operatively. Discussion: This observational study was designed to characterise transfusion practice in cardiac theatres and cardiac recovery to assess whether improvements could be made to our transfusion practice. We demonstrated a very high transfusion rate (66.0%) within our patient group with the majority of blood product units (61.2%) being transfused post-operatively. A wide transfusion threshold for RBCs was identified both pre and post-operatively and although thromboelastometry was used more frequently in theatre than the postoperative period, it was only used to guide a minority of non-RBC transfusions. This prospective audit was relatively small and although the aim was to include consecutive patients this was not achieved. However we were concerned to see our suspicions confirmed by the data we collected. These figures appear to be clinically significant in their difference to other published studies. We feel that there is great room for improving our transfusion practice and aim to do this with the following interventions. We have developed a blood transfusion guideline based on existing and well published recommendations, adapted to our local requirements. We will commence the use of a TEG-guided transfusion protocol including functional fibrinogen testing and, a soon to be acquired platelet function analyser. We have asked our surgical colleagues to propose a RBC transfusion trigger for use on the post-operative cardiac recovery unit which they run without the assistance of 24/7 critical care support. Finally we will re-audit of transfusion rates six months after the introduction of this approach. i Knowles S (ed.), Cohen H on behalf of the Serious Hazards of Transfusion (SHOT) steering group. The 2010 Annual SHOT Report 2011. www.shotuk.org. i Shaw RE, Johnson CK, Ferrari G, et al. Balancing the benefits and risks of blood transfusions in patients undergoing cardiac surgery: a propensity-matched analysis. Interactive cardiovascular and thoracic surgery 2013; 17: 96-103. i Galas FR, Almeida JP, Fukushima JT et al. Blood transfusion in cardiac surgery is a risk factor of increased hospital length of stay in adult patients. Journal of Cardiothoracic Surgery 2013; 8: 54. i Horvath KA, Acker MA, Chang H et al. Blood transfusion and infection after cardiac surgery. Ann Thorac Surg 2013; 95: 2014-201. Page 19 of 49 i Weber CF, Gorlinger K, Meininger D et al. Point of care testing: A prospective randomised clinical trial of efficacy in coagulopathic cardiac surgery patients. Anaesthesiology 2012; 117(3): 531-547. SALBUTAMOL INHALER IDENTIFIED AS HALOTHANE DURING TOTAL INTRAVENOUS ANAESTHESIA. Salota V*, Parras T**, Lanigan C** *Anaesthetic SpR, ** Consultant Anaesthetist. University Hospital Lewisham, London SE13 6LH Purpose/Objective We report a false positive anaesthetic vapour signal in a patient receiving inhaled salbutamol during total intravenous general anaesthesia. Material and Methods Forty-three year old male smoker, BMI 29.4 kg/m2, ASA I with no known allergies admitted for a daycase knee arthroscopy. Following the application of standard monitoring of ECG, NIBP, SpO2 and ETCO2, we induced general anaesthesia with Alfentanil 1 mg and Propofol at 200 µg/kg/min before inserting an I-gel size 5. Dexametasone and Ondansetron were also given. Anaesthesia was maintained with Propofol 120 µg/kg/min with an FiO2 of 50% oxygen in air, allowing spontaneous ventilation throughout. Oxygen saturation fell to 93% around ten minutes into the procedure. When auscultation revealed bilateral wheeze, we administered salbutamol from a metered dose inhaler (“Ventolin”) through a 50 mls syringe connected with a T-piece to the breathing circuit (fig 1). We were then surprised to see a screen display on the Aestiva/5 suggesting an endtidal halothane concentration of 8%, which rapidly decreased to 0% (figs 2 & 3). This coincided with the salbutamol administration and was repeated on several occasions. Oxygen saturation rose to 98%, and the remainder of the procedure and recovery were uneventful. Result The Aestiva/5 gas monitor failed to recognise the carrier gas norflurane in a salbutamol inhaler and mis-attributed it to halothane. Had we not been using TCI propofol, we might erroneously have reduced the anaesthetic vapour concentration, risking awareness under anaesthesia or worsening bronchospasm due to inadequate anaesthesia. Conclusion Some inhaled devices have the potential to interfere with infrared anaesthetic gas monitors1,2. References 1. Sellers WFS. Ventilator delivery systems for asthma inhalers. Br J Anaesth 2013; 110(5): 871P-872 2. Levin PD, Levin D, Avidan A. Medical aerosol propellant interference with infrared anaesthetic gas monitors. Br J Anaesth 2004; 92(6):865-9 Page 20 of 49 Figures Fig 1: Salbutamol inhaler connected to breathing system Fig 2: Anaesthesia monitor showing “Halothane” waveform while salbutamol is administered. Page 21 of 49 Fig 3: “Halothane” decreases to 0% following completion of administration of Salbutamol. Page 22 of 49 A SERVICE EVALUATION OF THE MONITORING OF SENSORY BLOCKADE IN LABOUR EPIDURALS Dr Swinda Esprit & Dr Francoise Iossifidis Background: Labour epidurals are commonly performed by Anaesthetists on Labour wards, but they are monitored by Midwives whilst in use providing analgesia for mothers in labour. At Darent Valley Hospital, patient observations whilst the epidural is in use are recorded on a proforma. The proforma gives guidance for the frequency of assessing the level of the sensory block achieved by the epidural. There is concern that the best practise is not being followed, and sensory block height is neither being assessed nor recorded. It is necessary to quantify this because there is a risk that “high blocks” will go unidentified, which is especially a risk if the patient goes to theatre and has the epidural “topped-up” with high dose local anaesthetic for an emergency procedure. A baseline assessment is also a necessary consideration before expanding the epidural provision to include “walking” epidurals, during which sensory block height monitoring is essential. Aims & Objectives: Aim – Is there best practice, in the monitoring of sensory blocks achieved by Labour Epidurals? Objectives- Quantify: 1. How often is the initial sensory block level check performed? 2. Is the sensory block checked whilst the epidural is in situ? If so, how often? 3. Average length of time labour epidural is in situ 4. Mode of delivery of baby for the women with epidural Design: Fifty-one sets of notes were randomly selected from women who had Labour epidurals placed in June 2012 on the Labour ward at Darent Valley Hospital. The labour notes were examined and data from the proforma recorded. Results: total of 51 notes examined. Full data recovered in 40/51 for duration of epidural and mode of delivery. 1. Initial block level check performed in 2/51 (4%) 2. Regular block level checks performed in 5/51 (10%) 3. Average length of epidural in situ- 4.8hrs, median length of epidural in situ5hrs 4. Outcomes: a. SVD 15/40 (37.5%), 1 went to theatre for MROP b. LSCS 13/40 (32.5%) c. Forceps delivery 7/40 (17.5%) d. Ventouse delivery 5/40 (12.5%) Number of epidurals “topped up” in theatre 26/40 (65%) Page 23 of 49 Conclusions: The sensory blocks of Labour epidurals are not being checked adequately and so there is the potential risk of a high block being missed. This is a particular risk when the epidural is “topped-up” with stronger local anaesthetic for an emergency operative procedure. Out of this audit’s population, 65% of epidurals ended up being topped-up. The absence of adverse events related to high blocks and labour epidurals may in part be due to the patient-controlled delivery system of the epidurals, so the epidural will only be topped up if pain is felt during labour. However, the emergency top-up risks respiratory compromise and complete spinal anaesthesia in the mother with an unrecognised spinal catheter. Therefore, best practise should be observed. Anaesthetists should also be aware of this risk when they are performing the top-up. As a result of the findings of this survey, we recommend re-education of the Midwives and Anaesthetists working on the Labour ward at Darent Valley Hospital, to explain the importance of monitoring sensory block height whilst an epidural is in situ. The epidural proforma should also be re-launched, and documentation of sensory block height emphasised. “Walking” epidurals have been shown to increase maternal satisfaction1. However if they were to be introduced, a culture where the epidural sensory block is recorded regularly is essential for safe maternal ambulation. Motor blockage would also need to be assessed formally; the Bromage scale2 would be suitable. References 1. McGrady, Elizabeth, and Kerry Litchfield. "Epidural analgesia in labour." Continuing Education in Anaesthesia, Critical Care & Pain 4.4 (2004): 114117. 2. Vallejo, Manuel C., et al. "Effect of epidural analgesia with ambulation on labor duration." Anesthesiology 95.4 (2001): 857-861. Page 24 of 49 AIRWAY MANAGEMENT IN THE EMERGENCY DEPARTMENT: LESSONS LEARNED FROM NAP4 A. Medniuk*, R. Grimaldi, P. Westhead Royal Sussex County Hospital, Brighton , UK gingerabb@yahoo.co.uk Purpose The 4th National Audit Project of the Royal College of Anaesthetists (NAP4) identified airway management outside of theatres as being high risk, with at least one quarter of reported adverse events occurring in the Emergency Department (ED) or Intensive Care Unit [1]. This finding prompted our institution to look into current practice in our ED. Method A retrospective case note review of all patients admitted through the ED as a “Trauma Call” over an eight month period was conducted. Inclusion criteria were adult patients (aged over 18), requiring intubation in the ED. Use of our ‘challengeresponse’ Rapid Sequence Induction (RSI) checklist was investigated along with data regarding airway management technique [2]. Results Thirty five patients out of 465 trauma calls (7.5%) required intubation in the ED, of which documentation was found for 22 (63%). No adverse airway events were documented as per NAP4 criteria [1]. Documentation of Airway Management Documented in the correct place 18/35 (51%) Documented somewhere in the case notes 22/35 (63%) RSI Checklist used 4/22 (18%) Difficult airway trolley present 5/22 (23%) Difficult intubation 9/22 (41%) Manual in line stabilisation used 13/22 (59%) Cricoid pressure applied 11/22 (50%) Capnography used 10/22 (45%) Discussion 1. Implementation of the RSI checklist is inadequate [2]. Awareness of it was found to be lacking, so formal training sessions have been arranged. 2. Incidence of difficult intubation is far more common than previously realised. It is hard to find concordance for a definition of difficult intubation, however the literature quotes a range of the order of 0.5-15% [3], which is significantly lower than our incidence. Planning for difficult/failed intubation [1], with available advanced airway management tools is required. 3. Adherence to standard practice and monitoring guidelines during RSI is not evident from the current documentation. 4. Currently, documentation of RSI undertaken in the ED is ad hoc. A new anaesthetic document has been produced to give efficient and clearly structured documentation of anaesthesia provision outside of theatres, for which formal training sessions are planned. Page 25 of 49 References 1. Cook T, Woodall N. Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 2: intensive care and emergency departments. British Journal of Anaesthesia 2011; 106 (5): 632– 42 2. First do no harm: a multifaceted study focusing on the use of checklists within the emergency department. Swann F, Brighton & Sussex Medical School, University of Sussex. 3. Emergency airway management: a multi-center report of 8937 emergency department intubations. Walls R, Brown C, Bair A, Pallin D, J Emerg Med. 2011;41(4):347. Page 26 of 49 CONVERSION OF EPIDURAL ANALGESIA DURING LABOUR TO SURGICAL ANAESTHESIA FOR EMERGENCY CAESAREAN SECTION: AUDIT OF CURRENT PRACTICE OF EPIDURAL TOP-UPS Buchanan Dr Salota V and Agarwal M Labour Ward, Maternity Unit, University Hospital Lewisham, London SE13 Introduction: Epidural mixtures containing local anaesthetic [LA] solutions with or without adjuncts are commonly used to extend labour epidural analgesia to surgical anaesthesia for emergency C-Section. There is still no consensus about the most appropriate choice of local anaesthetic solution[LA]despite previous studies[1,2]and guidelines. Given the rising C-Section rate in UK[3] and establishment of enhanced recovery programmes for elective C-sections[4], we sought to establish how extension of epidural blockade was achieved in a busy outer London Maternity Unit at University Hospital, Lewisham, London, UK. Aims The aim of this study was to determine current management and choice of Local Anaesthetic solutions with/without opioids for “topping-up” epidural analgesia to provide surgical anaesthesia for emergency C-section given the large number of rotating trainees who have been trained in other units. We aimed to discover which local anaesthetic solutions were used, volumes used, where they were administered, whether a test dose was used, whether an epidural opioid was given and where they were removed Methods 4 week observational study using a simple postal/e-mail questionnaire and sent to all Obstetric Anaesthetists covering Labour Ward { Consultants, Trainees comprising SpR/ST3-6/CT1-2 and Clinical Fellows[CF]/Staff Grades[SG]} Results Response Rate: 25/32 replies [>78% response rate] 5/10 CT1-2; 11/12 SpR; 4 CF/SG Test Dose: All Anaesthetists except 2 SpR’s gave a test dose before giving remainder of the dose Range of LA solutions and volumes 16 Trainees[SpR &CT1-2] 5/7 Consultants 65% 0.5% Bupivacaine alone/+2% Lignocaine[10-18mls] 0.75 % Ropivacaine [ 510mls] 35% 0.75% Ropivacaine [10-15mls] Incremental Doses Epidural Opioids: Most Anaesthetists usually/sometimes administered epidural Diamorphine at end Emergency C-Section. Fentanyl not used. Location Epidural Top-Up : All administered in Delivery Room or Theatre Removal Epidural: All removed Theatre or Recovery Findings Topping-up a working epidural gives good surgical anaesthesia for emergency CSection Majority of Consultant Anaesthetists used 0.75% Ropivacaine in small incremental doses 5-10ml Page 27 of 49 Majority Trainees still used 0.5% Bupivacaine either alone/or in combination 2% Lignocaine in larger doses [10-18ml]. Choice Local Anaesthetic solution depended on operator familiarity & preference Combination of adrenaline-bicarbonate-lignocaine not used. All epidural top-ups were undertaken in Delivery Room or Theatre Test Dose usually administered prior to giving full dose of top-up All epidural catheters removed theatre or Recovery Conclusions & Recommendations A working epidural facilitates provision of anaesthesia for surgery avoiding need for general anaesthesia, even for Category 1 C-sections with the appropriate & timely choice and volume of local anaesthetic solutions and opioids. There are advantages to enhanced recovery pathways even following emergency C-section in women without complications[4]. Given recent safety warnings about NSAID [especially Diclofenac] and Codeine in pregnancy, expression in breast-milk and effect on foetal respiration, every opportunity should be taken to maximise regional analgesia & anaesthesia. References Extension of Epidural Blockade for Emergency Caesarean Section: A Survey of Current UK Practice. Regan K.J. and O’Sullivan G.O. Anaesthesia 2008:63:136-142 Extending Epidural Blockade for Emergency Caesarean Section. A Comparison of Three Solutions Lucas DN, Ciccone GK, Yentis SM. Anaesthesia 1999:54:1173-7. Office for National Statistics; Births and Deaths in England and Wales 2011; Http:// www.ons.gov.uk/final 2012 Enhanced Recovery in Obstetrics: A New Frontier: Editorial Lucas DN, Gough KL. International J. Obstetric Anaesthesia 2013:22:92-95 Page 28 of 49 INVASIVE LINE INSERTION – DOCUMENTATION & CARE PRACTICE Dr M Kanagarathnam, Dr S Sparkes, Dr C Anderson Kings College Hospital NHS Trust Aim of the study: To identify and improve our standard of care in invasive line insertion Background: A 2006 prevalence survey showed 42% of blood stream infections are central line related in England. Introducing Matching Michigan principles and care bundles reduced Catheter related blood stream infections CRBSI from 7.7 to 1.4 per 1000 central line insertions. But this requires an audit to ensure the key policies and practices are implemented appropriately1. We are aware that there are a lot of care bundle packages used in several trusts across the country2. We also had recent critical incidences of arterial cannulation, misplaced guide wires, pseudo aneurysm and retroperitoneal haematomas. Method: After registration in our audit department we evaluated our critical care units looking at our invasive lines with details of documentation and visual inspection of the lines in a day. We used a standardised proforma to fill the details of the line type, site of insertion, date of insertion, documentation details, etc. Results: Out of the 82 invasive lines on the day of our study 27% of them had no documentation at all. 75% of the arterial lines which accounts to 50% of the lines are not documented. There was better documentation with central lines. 97% of the lines were secured appropriately. Complications were recorded in very few cases. 48% of the lines had no operator identifiable. All the subclavian and central lines have chest x-ray requested but only quarter of them being documented as checked. Page 29 of 49 Conclusion: This was presented in an interdepartmental meeting to raise the issue and formulate a solution. We debated about the reasons for poor documentation and the need for education with good support measures. For immediate impact this was presented to the trainees on induction every 3 months to raise the awareness of the problem. There is a future plan to create an invasive line documentation proforma to be filed into the notes with vision to extending this into our existing electronic record when intensive care is fully integrated into a paperless system. Our changes will be evaluated at regular intervals to improve the standard of care in line with General Medical Councils Good Medical Practice guidelines3 . References: 1 http://www.his.org.uk/files/3813/7088/0820/4_epic2_National_EvidenceBased_Guidelines_for_Preventing_HealthcareAssociated_Infections_in_NHS_Hospitals_in_England_2007.pdf 2 http://www.sicsag.scot.nhs.uk/HAI/SICSAG-central-line-insertion-bundle120418.pdf 3 http://www.gmc-uk.org/static/documents/content/GMP_2013.pdf_51447599.pdf Page 30 of 49 ASSESSING THE IMPACT OF TWO SIMPLE INTERVENTIONS TO IMPROVE POSTOPERATIVE BETA-BLOCKER AND STATIN ADMINISTRATION AND TROPONIN MEASUREMENT FOLLOWING MAJOR VASCULAR SURGERY H Arunachalam and M Harper Department of Anaesthetics, Royal Sussex County Hospital, Eastern Rd, Brighton, BN2 5BE European Society of Cardiology(ESC) guidelines recommend continuing betablockers and statins postoperatively and monitoring troponins following major noncardiac surgery 1 as raised levels are associated with worse outcomes 2. Following a baseline audit of local practice we now report the findings of a re-audit after the implementation of two simple interventions to improve compliance with the guidelines. The aim of the interventions was to ensure all patients taking statins and betablockers preoperatively received them on the first two days following their operation and to quantify the numbers of patients at a higher risk of morbidity by measuring postoperative troponin levels. We therefore affixed stickers to the drug charts exhorting ward staff to ensure beta-blockers and statins were administered postoperatively and provided pre-filled blood request forms for postoperative troponin measurements on the front of the patients’ notes. Data was collected for 100 consecutive elective major vascular patients. Improvements were seen in both drug administration and postoperative troponin monitoring. These are summarised in the table below. This audit indicates that simple interventions can lead to better compliance with the ESC guidelines for patients undergoing major vascular surgery. A high proportion of patients had raised troponins postoperatively but at which level this warrants intervention and what interventions are appropriate remain unclear. Preop Beta blocker Beta blocker administered post op Initial audit %(number) 32% (16) 12% (6) Re-audit %/(number) 32% (31/97) 65% (14/22) Preop Statin Statin administered post op Tn measured Day 0 Tn measured Day 1 Tn measured Day 2 Tn >14 ng/L d1 Tn >14 ng/L d2 Tn increase 80% (40) 60% 0 10% (5) 2% (1) NA NA NA 90% (87/97) 79% (58/74) 1% (1/91) 89% (71/80) 70% (52/75) 56% (41/73) 58% (30/52) 52% (27/52) Change +53% +10% +19% +1% +79% +68% Reference(s) 1. Poldermans D, Bax JJ, Boersma E, et al. Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: the Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Noncardiac Surgery of the European Society of Cardiology (ESC) and endorsed by the European Society of Anaesthesiology (ESA). Eur Heart J 2009;30:2769-812. 2. Winkel TA, Schouten O, van Kuijk J-P, Verhagen HJM, Bax JJ, Poldermans D. Perioperative asymptomatic cardiac damage after endovascular abdominal aneurysm repair is associated with poor long-term outcome. Journal of Vascular Surgery 2009;50:749-54. Page 31 of 49 TRAINING PROFESSIONALS: A NOVEL APPROACH TO EDUCATIONAL SUPERVISION AND NON CLINICAL LEARNING Dr Andrew Pool1, Dr Oliver Long2, Dr Simon Lambden3 1Kings College Hospital, 2Croydon University Hospital, 3University College Hospital Introduction The Training Professionals project was one of 9 winners selected nationally from over 200 applications to the Inspire Improvement competition and is receiving funding from Health Education England (HEE) as part of the Better Training Better Care initiative. We believe it could represent a future model for non-clinical teaching and educational supervision for trainees. Making the Trainee the centre of their own training and responsible for their own successes will better prepare them for the roles and responsibilities of a modern NHS Consultant. There are three main aspects to our project:1. Trainee produced goals and delivery plan: We have split the non-clincal aspects of training into four perspectives – Knowledge & Education, Audit, Research and Corporate & Management. At the start of each training block trainees will develop goals within each perspective. The goals will be described as having a tiered level of success – Bronze, Silver and Gold. Bronze represents the minimum requirements for that block, whilst Silver and Gold describe success beyond the basic curriculum requirements. Trainees then produce a delivery plan for the achievement of those goals, each step. 2. Trainer Facilitation: To support and supervise trainees as they achieve their goals Educational Supervisors will have a more regular role in overseeing their trainees. The Trainee will update their goals and delivery plan onto a ‘cloud’ based document. The Trainee and Educational Supervisor will interact remotely on a weekly basis via this document, the Trainee updating progress and the Educational Supervisor providing advice, support and direction. If the trainee appears to be failing to meet their agreed goals, either party can initiate a face-to-face meeting to re-evaluate the Trainee’s progress. For Educational Supervisors the tool provides evidence of the fulfillment of their responsibilities for appraisal and revalidation. 3. Trainee Resource and Time Ownership: The tool developed allows trainees to demonstrate success in their professional development and effective use of time allocated such that they should be given greater control over their non-clinical teaching time. The Trainee will effectively be given the equivalent of Consultant SPA time on the agreement that they meet their goals. Progress The Phase I pilot is underway with a cohort of senior Anaesthesia trainees and their educational supervisors at King’s College and once validated is planned to roll out to all trainees in the department as well as recruiting other departments Page 32 of 49 regionally/nationally. With backing from the HEE we are keen to spread awareness and recruit other Trusts as the scope of the project is widened. Validation Qualitative: Likely survey of trainer and trainee before implementation and at 3 and 6 months Quantitative: Blind assessment of trainee performance before implementation and at 6 months Summary We believe teaching time should be of measurable benefit to trainees and that there should be high quality demonstrable weekly interactions with supervisees. Training professionals can deliver this. Once Training Professionals produces evidence that both Trainees and Educational Supervisors find it of benefit and that it demonstrates real improvements to Trainee’s career progression we hope that it will be incorporated into training program curricula and either work alongside or within Trainee’s e-portfolios. Page 33 of 49 MYXOEDEMA MADNESS: TO HALLUCINATE OR TO INTUBATE? ABSTRACT Dr Omar Siddique (ACCS Anaesthetics CT1: Darent Valley Hospital) May 2013 CJ a 55 year old male was admitted to a psychiatric unit due to increased agitation, confusion and odd behaviour. He had no past medical history of note. CJ was under stress after being made redundant and low in mood prior to admission. A set of blood tests were taken and revealed T4 – 6.3 with TSH 162.27 therefore was referred for medical admission with Hypothyroidism. On admission his condition rapidly deteriorated becoming increasingly aggressive and agitated despite sedation with Olanzapine, Haloperidol and Diazepam. CJ developed auditory and visual hallucinations and was non compliant with medication and aggressive towards staff. He was subsequently intubated and ventilated in order to facilitate treatment and taken to ITU for further management. CT head was performed, which detected no abnormality. He was commenced on 25mcg Levothyroxine via NG tube and given 48 hours of IV Liothyronine 10mcg BD. The patient unfortunately self-extubated however his condition improved and psychosis had resolved therefore was transferred to the ward. One week later the patient was discharged home on long term Levothyroxine. Primary hypothyroidism with myxoedema psychosis is a dangerous yet reversible condition. Patients with low thyroid hormone can often present with psychosis and delirium alone. Diagnosis is usually made by lab testing, and treatment is thyroid replacement. If untreated can lead to coma, and irreversible damage due to chronic metabolic changes to the brain. CJ was intubated to facilitate early treatment and prevention of coma and deterioration. Patients often require heavy sedation and can exhibit severe psychiatric symptoms. There are a wide variety of subtle manifestations of hypothyroidism making it an easily missed diagnosis. Thyroid hormone dysfunction should be considered in all patients with new psychiatric symptoms. If identified early, rapid treatment can be effective and life-saving. References: 1. Asher R. Myxoedematous madness. Br Med J 1949;2:555-62, 2. Gupta SP, Gupta PC, Kumar V, et al. Electroencephalographic changes in hypothyroidism. Inidan J Med Res 1972;60: 1101-6, 3. Vanderpump MP, Tunbridge WM. Epidemiology and prevention of clinical and subclinical hypothyroidism. Thyroid. 2002;12:839–847., 4. Benvenga S, Lapa D, Trimarchi F. Don't forget the thyroid in the etiology of psychoses. Am J Med. 2003;115:159– 160 Page 34 of 49 NOT JUST A UTI; EMPHYSEMATOUS PYELONEPHRITIS Dr Preeya Chakraborty MB BS FRCA, Dr Wessam Nabeih MB BCh FCAI Emphysematous pyelonephritis is a rare life-threatening condition where there is an infection, commonly an ascending urinary tract infection, resulting in a suppurative, gas forming disease of the renal paranchyma. The commonest causative organism, by far is E.Coli. Unsurprisingly, the disease is more common in women (who are more prone to urinary tract infection) and in poorly controlled diabetics. In the latter group, a triad of high glucose levels in the tissue, gas-forming bacteria and impaired tissue perfusion, facilitate the production of carbon dioxide and hydrogen via fermentation of glucose and lactate. There is much debate within the specialty of Urology regarding optimal treatment of these patients. Due to the relative rarity of this disorder, no clinical institution worldwide has been able to define guidelines regarding important prognostic factors or optimal management strategy for the treatment of the disease. Nephrectomy was traditionally the gold standard of treatment, but in recent years, antibiotic treatment, paired with percutaneous drainage, has gained popularity. Review of the literature seems to favour aggressive medical management and insertion of percutaneous nephrostomy, but with early consideration of nephrectomy. Renal preservation, particularly in bilateral disease, is also key to decision making in this regard. We present a case of E.coli emphysematous Pyelonephritis in a 78-year old poorly controlled female diabetic, who was medically managed, with a successful outcome. References: LearningRadiology.com – Emphysematous Pyelonephritis: USA: Einstein Medical Center in Philadelphia , Pennsylvania; 2002 Available from http://www.learningradiology.com/notes/gunotes/emphysemapyelopage.htm Goichot B, Andres E. Emphysematous Pyelonephritis. New England Journal of Medicine. 2000: 342:60-61 Huang J, Tseng C. Emphysematous Pyelonephritis, Clinicoradiological Classification, Management, Prognosis and Pathogenesis. Arch Internal Medicine.2000 March; (Vol 160):797-805 Available from http://archinte.jamanetwork.com Shokeir AA, El-Azab M, Mohsen T, El-Diasty T. Emphysematous Pyelonephritis: a 15-yr experience with 20 cases.Urology. 1997; (49):343-346 Page 35 of 49 DIAGNOSING TETANUS Dr Preeya Chakraborty MB BS FRCA, Dr Harpreet Gill MbChB Tetanus is a disease, which is relatively rare in the UK; there were 198 reported cases of tetanus in England and Wales, within a twenty-year period (1984-2004). The causative organism is Clostridium tetani, a neurotoxin producing bacteria. Tetanus immunization was first introduced in the UK armed forces in 1938, and became part of the National Immunisation Programme for infants in 1961. High risk groups for contracting the disease (due to poor immunization status) are neonates, the elderly and intravenous drug users. We present a case of tetanus, which had a relatively insidious onset. It responded to empirical treatment, although the patient needed mechanical ventilation. It is imperative to treat the patient in view of their clinical symptoms, since a plasma diagnosis may be belated, taking weeks to return from the highly specialised laboratories, that run this assay. Given the rare incidence of tetanus, clinicians in the UK tend to be relatively inexperienced at diagnosing and treating this potentially fatal disease. We aim to raise awareness of the clinical presentation, and encourage a differential diagnosis of tetanus to be at the forefront of the clinicians’ mind. References: Hawker J, Begg N, Weinberg J, Blair I, Reintjes K. Communicable Disease Control Handbook. Blackwell Science; 2001 HPA.org.uk. Public Health England: Epidemiology; 2010 (updated 8 August 2013) Available from: http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/Tetanus/Epidemiologi calData/tet01TetanusCasesAge. Page 36 of 49 RECOGNITION & MANAGEMENT OF ACCIDENTAL DURAL PUNCTURE & PDPH AT LEWISHAM MATERNITY UNIT: A RETROSPECTIVE AUDIT R Mistry and M. Agarwal Lewisham Healthcare NHS Trust, London, UK ravin.mistry@nhs.net Dural puncture (DP) whilst performing epidural or spinal analgesia/anaesthesia can be deliberate (“mini spinal” or spinal anaesthesia) or inadvertent. Post-dural puncture headache (PDPH) is a rare but significant complication1. Practice may vary amongst trainees and consultants in managing accidental DP whilst siting epidural catheters, be it re-siting at an alternative level or siting an intrathecal catheter. Our current local guideline suggests the former approach. Methods A retrospective 12-month report was generated from our local obstetric database auditing 1.The incidence of accidental DP, 2. The management of accidental DP and the incidence/management of subsequent PDPH and, 3. The incidence and management of all PDPHs. Results 2600 central neuraxial procedures were undertaken in the 12- month study period. The overall incidence of PDPH was 1%. Of the 26 cases of PDPH, 21 were after epidural analgesia, 3 following spinal anaesthesia for Caesarean section and 2 following combined spinal-epidural anaesthesia. 10 of 26 cases of PDPH required an epidural blood patch. Of the 21 cases of PDPH following epidural analgesia, 11 cases were recognised at the time - 6 had obvious CSF flow from the Tuohy needle and 5 had CSF aspirated from the catheter. Of these 11 cases, 9 were re-sited in an alternative space and 2 were managed as intrathecal catheters. 3 of the 9 re-sited epidural catheters required a blood patch. Both cases of intrathecal catheter required a blood patch. Conclusions The use of intrathecal catheters is rare in our unit. There were no adverse outcomes reported with the 2 intrathecal catheters placed. Our PDPH rate remains unchanged at approximately 1%. The majority of PDPHs were managed conservatively. Our local policy remains to not advocate the use of intrathecal catheters in the vent of inadvertent DP. If an intrathecal catheter is sited, we suggest a local2 or national guideline should be in place to provide analgesia and anaesthesia via this route to minimise maternal and fetal morbidity and mortality. 1. Epidural Information Card. OAA. http://www.oaaanaes.ac.uk/assets/_managed/editor/File/Info%20for%20Mothers/EIC/2008_eic_ english.pdf. 2. http://www.rcht.nhs.uk/DocumentsLibrary/RoyalCornwallHospitalsTrust/Clinical/A naesthetics/GuidelineForTheManagementOfAccidentalDuralPuncture.pdf. Page 37 of 49 ANAESTHETIC ASSESSMENT AND MANAGEMENT OF THE AIRWAY IN OVERWEIGHT AND OBESE PEOPLE AT DVH DARTFORD Dr M Pemmaraju1, Dr K Reid2, Dr M Satisha3 Dr R Madan4 1,2 Specialist Registrars, 3,4Consultant Anaesthetists, Darent Valley Hospital, Dartford 1 pemmarajum@gmail.com, BACKGROUND: Obesity is becoming an increasing problem in the U.K. Anaesthesia for the Obese is a recognised risk issue. Managing and Securing the Airway in obese patients is often challenging and there is a definite risk issue attached to managing airways and providing anaesthesia for the obese. INTRODUCTION: Obesity is defined as a BMI greater than 30kg/m2. The concept of bariatric anaesthesia is relatively new in the UK. This audit is a local initiative to help improving the standards and provide essence of care in keeping with the recommendations and guidelines laid by existing societies. AIMS AND OBJECTIVES: • To assess existing practice. • To improve standards of care. • To create local protocols. • To re-audit and look for any improvement. METHODOLOGY: Patient’s records were reviewed prospectively over a period of four weeks during the year 2011 and the results were compared with those of re-audit done in 2012. RESULTS: Results: Less than 10% of the obese patients were referred to Anaesthetist for preoperative assessment. While majority of obese patients were anesthetised by Consultants, about 40% were anaesthetised by other junior grades. Documentation of airway assessment was better in the re-audit but still could be much better. CONCLUSIONS: Only small proportion of obese patients were referred to Anaesthetist. There is increased use of regional anaesthesia during the recent audit compared to the earlier audit. There is a need to improve documentation of airway assessment in this patient population. Anaesthetic charts need to be redesigned to incorporate these changes. REFERENCES: 1. Peri-operative management of morbidly obese patient-AAGBI-2007 2. Anaesthesia for obese patients-The Society for Obesity and Bariatric Anaesthesia guidelines. Page 38 of 49 SAFE USE OF OXYGEN CYLINDERS: AN UNANSWERED SAFETY ALERT Dr Andrew McKechnie and Dr Beccy Campbell Background Following the tragic fire at Royal United Hospital Bath, a national patient safety alert (NPSA) was issued regarding the use of oxygen cylinders during patient transfer. Therefore we decided to audit practice within our district general hospital (DVH) when transferring patients to and from theatre, from theatre to the recovery area and within ITU. Methods A survey was distributed to members of the multidisciplinary theatre team regarding their knowledge and experience of working with oxygen cylinders. Subsequently oxygen cylinder use was observed within main theatres, obstetric theatres and the ITU. Data was collated and analysed in Microsoft excel. Results Survey Question Are you aware of any guidelines governing safe use of oxygen cylinders? Are you aware of any guidelines governing use and transport of O2 when transferring patients? Have you experienced patient safety issues using portable O2 cylinders? Have you had any formal training in safe use of oxygen cylinders? Observation Transfer Observed Ward to Theatre Theatre to Recovery Delivery Suite ITU Overall Cylinder Safe % 0 53 0 20 38 YES % 33 NO % 67 47 53 47 53 13 87 Cylinder unsafe % 100 47 100 80 62 Conclusions Our audit clearly shows that further education regarding the safe use of oxygen cylinders is required. We plan to issue guidelines regarding cylinder use and will reaudit. References Page 39 of 49 Kelly, F. E., Hardy, R., Hall, E. A., McDonald, J., Turner, M., Rivers, J., Jones, H., Nolan, J. P., Cook, T. M. and Henrys, P. (2013), Fire on an intensive care unit caused by an oxygen cylinder. Anaesthesia, 68: 102–104. doi: 10.1111/anae.12089 K. Edmonds, M. John, R. John, Closing the door on fire, Anaesthesia, 2013, 68, 8 http://www.bathchronicle.co.uk/Staff-relive-wall-RUH-intensive-care-unitinquest/story-19501214-detail/story.html AUDIT OF PREVENTATIVE MEASURES FOR DEEP VENOUS THROMBOSIS IN NEUROSURGICAL PATIENTS NM Canchi, E. Lillie, R. Santhirapala, G Dezylva. King’s College Hospital London Background: Incidence of thromboembolic complications in neurosurgical patients is a significantly high. Deep Vein Thrombosis (DVT) is 25% and Pulmonary Embolus (PE) ranges between 9 to 50%. Heparin prophylaxis in this group of patients is to be balanced against risk of bleeding complication (RR 1 – 3.9%). Aim: Our aim was to evaluate whether current DVT prophylaxis in our neurosurgical unit is in accordance with local protocol. Methods: The audit was conducted as a retrospective, case-note review of adult patients undergoing neurosurgical procedures in our centre. We excluded patients undergoing interventional procedures, patients directly transferred to intensive care unit post operatively and Paediatric patients. Data was collected regarding the type of surgery, duration, and risk assessment as per local guideline, pre-operative anticoagulant use, any intraoperative VTE preventative measures and postoperative administration of thromboprophylaxis. We also noted any subsequent complications or delayed heparin administration in the postoperative phase. Outcomes noted during the audit phase were DVT, PE or any bleeding sequelae in this group of patients. Results: A total of 45 patient case notes were followed during the phase of the audit. Nearly 2/3rd of the patients underwent intracranial surgery and the remaining had extra cranial surgery. 20/45 patients had a risk score of 3 and 16/40 had a VTE risk score of 2. While a small proportion 5/45 of the patients scored > 3 on the VTE scores. We noticed non-adherence to the protocol (i.e. delayed start of prophylaxis) with 7/45 patients during the audit. 6/7 had intracranial surgery. 1/7 patient among the group went on to develop DVT on day 40 and subsequently was commenced on enoxaparin. 100% of the patients undergoing surgery had suitable intra-operative preventative measures and 100% of patients who were on anticoagulants pre-operatively were recommenced on those medications in the immediate postoperative phase. Page 40 of 49 We found no cases of post-operative bleeding in patients started on prophylactic therapy. Conclusions: We had a low incidence of complications, with a single case of DVT. Audit showed no particular problems with respect to bleeding post-operative due to thromboprophylaxis. KEEPING NICE AND WARM Dr Pemmaraju1, Dr Madhusudhan Puchakayala2 1 Specialist Registrar, 2Consultant Anaesthetist Guys and St Thomas’s Hospital 1 pemmarajum@gmail.com, 2Madhusudan.Puchakayala@gstt.nhs.uk BACKGROUND: NICE published Inadvertent perioperative hypothermia (NICE clinical guideline 65) in April 2008, which recommends that each patient undergoing anaesthesia should be assessed for risk of inadvertent perioperative hypothermia and forced air warming used where indicated to keep patients warm. The purpose of this audit is to assess the prevalence of periop. Hypothermia in our trust and see whether or not they are in concordance with NICE guidelines. INTRODUCTION: Inadvertent perioperative hypothermia is a recognised and common occurrence during surgery. There are a number of reviews of the adverse effects of inadvertent peri-operative hypothermia (IPH) in the literature. Research has shown that IPH can lead to morbidity including prolonged recovery and hospital stay. AIMS AND OBJECTIVES: Re-audit of an audit done in 2009 and 2010 on Perioperative Hypothermia at GSTT. Assess prevalence of perioperative hypothermia in our trust. compare concordance with NICE recommendations METHODOLOGY: This is a prospective re-audit covering both Guys and St Thomas sites. Each theatre was provided with a three part questionnaire based on NICE guidelines to be completed by ODP, Anaesthetist and Recovery staff. The data obtained was analysed and comparisons drawn against proposed targets suggested in NICE guidelines and against the audit done in 2009-10. RESULTS: 86 complete forms were collected and data in those forms were at varying levels of completion. Pre op temperature measurement in the ward has improved to 85% compared to 80% in 2010, and 29 % in 2009. 81% of patients had temperature monitoring (34% in 2010 and 37% in 2009). 90% of the patients had active warming measures (94% in the high risk group & 83% in the low risk group) - Similar to 2010 data. 90% of the patients entering recovery are normothermic (irrespective of risk). Temperature at discharge >= 36. CONCLUSIONS: Awareness has increased among nursing staff, ODAs and may be doctors. The availability of forced air warming devices was approx. 60% excluding day surgery in 2009 compared to 100% in 2010. Fluid warmers are available more freely. Page 41 of 49 REFERENCES: 1. 2. 3. 4. 5. Inadvertent perioperative hypothermia (NICE clinical guideline 65) - April 2008 Recommendations for Standards of Monitoring during Anaesthesia and Recovery (4th Edition). Frank SM et al. Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events. A randomized clinical trial. J Am Med Assoc. 1997;277:1127–1134. Scott EM et al. Effects of warming therapy on pressure ulcers – a randomized trial. AORN J 2001;73:921–927, 9–33, 36–38. Kurz A, Sessler DI, Lenhardt R. Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group. New Engl J Med 1996;334:1209–1215 AAGBI, London 2007 Page 42 of 49 SEPSIS IN PREGNANCY Dr Francoise Iossifidis MD, FRCA Consultant Anaesthetist, Lead Obstetric Anaesthetist, Darent Valley Hospital The eighth report of the United Kingdom Enquiries into Maternal Deaths “Saving Mothers’ Lives”, was published in March 2011. For international comparison, the UK Maternal Mortality Ratio for 2006–8 is 6.69 per 100 000 live births. The true UK maternal mortality rate, calculated from all maternal mortality directly or indirectly due to pregnancy identified by this Enquiry, for 2006–8, was 11.39. The 2006-08 report showed a small decline in overall maternal death for the first time in many years, and a large reduction in the number of Direct death due to pregnancy. However, deaths from infection of the genital tract i.e. sepsis, mainly from community-acquired Group A Streptococcal disease, have increased. The overall rate has increased to 1.13 deaths per 100 000 maternities compared with 0.85 for 2003-05. This is on a background of an increased death rate from Group A Streptococcal infection in the general population but also prior to the H1N1 pandemic. In this report sepsis was the top cause of death and the following recommendation was made as part of the top ten recommendations. “There is an urgent need for a national clinical guideline to cover the identification and management of sepsis in pregnancy, labour, and the post-natal period. Until such time as a national guideline is developed, the guidelines for the management of acute sepsis developed and updated by the Surviving Sepsis Campaign should be used.” As a result the Royal College of Obstetricians and Gynaecologists produced the Green Top Guideline no64a “Bacterial Sepsis in Pregnancy” which emphasizes the back to basics approach recommended by the CMACE report. It highlights the ten red flags described in the report for the diagnosis of sepsis and takes a lot of the recommendations from the “Surviving Sepsis Campaign”. The ten red flags are: Pyrexia 38C. A normal temperature does not exclude sepsis. Paracetamol and other analgesics may mask pyrexia, and this should be taken into account when assessing women who are unwell; sustained tachycardia .100 beats/ min; breathlessness abdominal or chest pain; diarrhoea, vomiting, or both; reduced or absent fetal movements, or absent fetal heart; spontaneous rupture of membranes or significant vaginal discharge; Page 43 of 49 uterine or renal angle pain and tenderness; The woman is generally unwell or seems unduly anxious. Due to the changes in physiology associated with pregnancy and the fact that it is a normal state the diagnosis of sepsis can be difficult. The increase use of MEOWS charts should help but its use is still not widespread. Early and prompt referral to hospital and treatment by intensivists is recommended. These patients should be treated by senior clinicians. The guideline follows the SSC recommendation with antibiotics within an hour of diagnosis, fluid resuscitation, invasive monitoring and inotropes. The main issue is that these women are first seen by midwives who are used to seeing normal deliveries and junior doctors not exposed to seriously ill patients. A big effort has been placed on training all team members in recognising sepsis. MMBRACE should produce the next report in the near future. The issue to look at is not only mortality but the morbidity associated with sepsis. 1. Saving mother’s lives Reviewing maternal deaths 2006-2008 The Eighth Report of the Confidential Enquiry into Maternal Deaths in the UK. 2. RCOG Green Top Guideline No 64a, Bacterial Sepsis in Pregnancy. Page 44 of 49 Dr. M. Javaid Consultant Nephrologist Darent Valley Hospital, Dartford Acute kidney injury is a frequent occurrence on ITU. The condition is often associated with high mortality, morbidity and prolonged hospital stay. In majority of cases the underlying cause is related to sepsis, drugs or volume problems, however in some patients the pathology can be multifactorial. Such patient can present with atypical features making the diagnosis difficult and tricky. One needs to be mindful of such conditions and high index of suspicion is needed for proper diagnosis and management’’. Dr Armando Gonzalez Consultant Microbiologist Darent Valley Hospital, Dartford & Gravesham NHS Trust Invasive candidiasis is a severe fungal infection which is not uncommon in ITU patients. Predisposing factors include prolonged ITU stay, total parenteral nutrition, complex/multiple abdominal surgery, steroids and antibiotic treatment. A high index of suspicion required for timely diagnosis as candidaemia is not always present. Management guidelines have been recently updated following the development of equinocandins, a new class of efficacious and safe antifungal drugs. As most cases of candidaemia are secondary to IV line infection, withdrawal/change of central lines is mandatory, together with daily clinical examination and fundoscopy to rule out invasive candidiasis to define length of treatment. ANAESTHETIST IN CARDIAC CENTRE Dr M Satisha Consultant Anaesthetist, Darent Valley Hospital Dartford & Gravesham NHS Trust Anaesthetists are asked to be present/assist/sedate number of patients outside operating theatre. Numbers of interventions in cardiology are ever increasing. It is not uncommon in small district hospitals to have a dedicated anaesthetist doing sessions outside operating theatre. Anaesthetising a patient in remote locations is not without complications. In addition to patient related problems with anaesthesia, there are lots of organisational factors to be taken into account. My presentation will try to focus on some of these issues. Page 45 of 49 ULTRASOUND FOR THE ANAESTHETIST Dr Richard Beese Consultant Radiologist Darent Valley Hospital, Dartford & Gravesham NHS Trust The talk is on: The point of care ultrasound The history: The current status and the future with relevance to anaesthetists Page 46 of 49 OUR SPONSORS Sponsor Representative Spacelabs Jas Sihra B Braun Sally Jones LIDCO Phillip Ellis Wesleyan Dawn Mitchell Brian Smith Mediplus Adam Murr Fresenius Kabi Julia Donovan Page 47 of 49 VOTE OF THANKS I am extremely grateful to all those who have helped out and supported the meeting. I would like to thank my colleagues who went the extra mile to help me to organise the event. I also want to thank Jackie Shone and Trish Bannister for their help. A special note of thanks and appreciation goes out to Helen Langman without whom it would have been difficult to put everything together. Finally, I feel that I must thank my wife and daughters for their patience in the last few days and letting me get on with the ‘preparation’ for the Meeting. Dr Raman Madan FRCA Consultant Anaesthetist Darent Valley Hospital, Dartford Page 48 of 49 Page 49 of 49