Traditional Nutrients in the Prenatal Period Nutrient Vitamin E Vitamin A Vitamin D Vitamin K What Does It Do Deficiency Creates Good Sources: Precise role in fertility is unknown. Yet it is considered the fertility vitamin because rats are proven to be unable to reproduce without it. Since the human placenta shares the same protein as rats that transports Vitamin E across the placenta to build its nutritional transport system- it is considered very likely that Vit.E plays the same role in humans. Necessary for the differentiation and patterning of all the cells, tissues and organs within the developing fetus (and for continued growth after the development and formation period). It is especially important for the developing brain. ' Vitamin A is also necessary during fetal development and through adult life to maintain the presence of cells lining the lungs that are covered in hair-like projections called cilia." These hairs sweep away debris and foreign material, protecting the lungs from pollutants and infectious diseases. In the third trimester the fetal skeleton enters a period of rapid growth that requires Vit D (in combo with calcium & phosphorus). May play a role in lung development. And likely plays a large role in fetal development because it work’s closely by interacting with Vit. A. At birth the infants level’s are correlate to the mother’s levels. One study showed no detectable Vit. D in the mother or babies. Vit.D even helps to tone the uterus – helping the uterus to contract properly during labor Development of proper facial proportions and development of the nervous system. The enzyme that uses it to activate vitamin K-dependent proteins first shows up in the skeletal and nervous tissue of the embryo. Mice who lack this protein for transporting Vit. E create visibly malformed placentas within 9 days and the offspring die within 11-15 days. Palm Oil Grass fed animal fat Nuts Seeds Fresh fruit and vegetables Freshly ground grains Early research into Vitamin A deficiency during pre conception and pregnancy produced spontaneous abortion, prolonged labour and death of the mother and her offspring during labour, eye defects including the complete absence of eyes, defects of the snout, dental arches and lips, displacement of internal organs, including the kidneys, ovaries and testes and deafness due to degeneration of the nervous system. Organ meats Liver Milk Eggs Butter Cod Liver Oil Even mild Vitamin A deficiency can predispose a person to poor kidney function later in life. Adequate levels protect the newborn from tetany, convulsions and heart failure. Low maternal vitamin D levels are implicated in infertility, gestational diabetes, preeclampsia and an increased risk of c-section1,2 Potential defects in the face, nervous system and lungs. Very little is known about the role of vitamin K in embryonic and fetal development. Two vitamin K-dependent proteins, bone Gla protein and matrix Gla protein, are present in the first trimester. These proteins help lay down calcium salts in bone tissue and keep calcium out of the soft tissues where it does not belong. Sunlight Cod liver oil Fatty fish Shellfish Butter Lard K1 Leafy green vegetables K2 Fermented foodsespecially natto Grass fed animal fatsespecially goose liver cheese and to a lesser extentbutter and egg yolk © 2013 Nourish Mama. All rights reserved. Certified Nutritional Wisdom for the Childbearing Years® Practitioner Nutrient DHA Biotin Folate (absorption is dependant on zinc status) Choline Glycine Zinc What Does It Do Deficiency Creates Good Sources: Formation of neurons synthesis of the important brain lipid phosphatidylserine: it is also the precursor to an important compound that protects neurons when they are assaulted by oxidative stress. The fetus hoards DHA from the mother and incorporates it into its brain at 10 times the rate at which it can synthesize it. Critical for fetal growth and development. Deficiency seems to common in pregnant women. 13 Suboptimal brain and eye development. Indeed low omega-3 levels are implicated in male infertility as men suffering from infertility suffer significantly lower levels of omega-3 fatty acids in their sperm than men of normal fertility2 Cod liver oil Fatty Fish Small amounts in grassfed animals Caviar Intrauterine growth retardation 14, limb and palate defects in rats. Liver egg yolks Whole wheat bread Cheese Avocado Salmon Chicken Pork Artichoke Raspberries Necessary for the production of new DNA and DNA is needed for new cells. Need to expand blood supply in the mother. Increases birth weight. Direct role in development of the brain. The formation of the connections between neurons, called synapses which continue at a high rate through to the 4th year of life. Choline is particularly critical in tooth development3 Indeed, a mother’s intake of choline during pregnancy may improve the capability for memory in her child4,5, Limiting factor for protein synthesis in the fetus so almost certainly a factor for fetal growth. The fetus can obtain it from the mother or can synthesize it in the presence of foliated and another amino acid serine. Neural tube defects (defects of the brain and spinal cord) May prevent spontaneous abortion, mental retardation. Deformations of the mouth, face and heart. Neural tube defects6 Maternal intake of choline might significantly decrease cognitive dysfunction seen in Downs Syndrome, at least in mice7. Liver Legumes Greens Asparagus Beets Liver Egg yolk Grass fed dairy To a lessor extent: meat, crucifers, nuts and legumes Intrauterine growth retardation Collagen rich foods such as skin and bone broth. Consumption of the mineral zinc alone as well as in combination with antioxidants like vitamins C and E shows promising results for men suffering Zinc on its own or in combination with vitamins C and E improves sperm quality in infertile men8. For women, too, zinc is essential to reproductive health and to the health of infants developing in their wombs. In a study of pregnant Canadian women, those with the highest overall intake of zinc were the least likely to suffer from symptoms of depression12. Glycine can be depleted with excess methionine (another amino acid) high in eggs and meat. Therefore a mother should match her eggs and meat with skin and bone broth, liver, legumes and greens. Male infertility 9 Shellfish Low maternal intake of zinc is associated with asthmatic symptoms in children10. Maternal zinc deficiency is also implicated in birth defects, low birth weight, intrauterine growth retardation, a tendency toward high blood pressure, behavioral problems, impaired immune function and fetal death11. © 2013 Nourish Mama. All rights reserved. Certified Nutritional Wisdom for the Childbearing Years® Practitioner References 1. Barrett, et al. Vitamin D and pregnancy: An old problem revisited. Best Practices & Research, Clinical Endocrinology & Metabolism. August 2010. 2. Lewis, et al. Vitamin D deficiency and pregnancy: from preconception to birth. Molecular Nutrition & Research. August 2010 3. Nandasena, et al. Archives of Oral Biology. August 2010. 4. Zeisel, et al. Perinatal choline influences brain structure and function. Nutrition Reviews. April 2006. 5. Zeisel. The fetal origins of memory: the role of dietary choline in optimal brain development. Journal of Pediatrics. November 2006. 6. Zeisel. Choline: needed for normal development of memory. Journal of the American College of Nutrition. October 2000. 7. Moon, et al. Perinatal choline supplementation improves cognitive functioning and emotion regulation in the Ts65Dn mouse model of Down syndrome. Behavioral Neuroscience. June 2010 8. Omu, et al. Indications of the mechanisms involved in improved sperm parameters by zinc therapy. Medical Principles & Practice. 2008 9. Colager, et al. Zinc levels in seminal plasma are associated with sperm quality in fertile and infertile men. Nutrition Research. February 2009. 10. De Luca, et al. Fetal and early postnatal life roots of asthma. Journal of maternal-fetal neonatal medicine. October 2010. 11. Urlu-Adams, et al. Zinc and reproduction: effects of zinc deficiency on prenatal and early postnatal development. Birth Defects Research. August 2010. 12. Roy, et al. Higher zinc intake buffers the impact of stress on depressive symptoms in pregnancy. Nutrition Research. October 2010. 13.http://journals.lww.com/nutritiontodayonline/Abstract/2012/03000/Biotin___Crit ical_for_Fetal_Growth_and_Development.10.aspx 14. http://www.ncbi.nlm.nih.gov/pubmed/4059664 15. Masterjohn Chris, Vitamins for Fetal Development, Wise Traditions, Healthy Baby Issue © 2013 Nourish Mama. All rights reserved. Certified Nutritional Wisdom for the Childbearing Years® Practitioner