Host-Pathogen Interactions
The course will provide a basic introduction to different pathogens and host immune
responses. This will be followed by an in-depth analysis of the immunological, cellular,
molecular and genetic mechanisms in pathogen biology and pathogen-host interactions.
Topics will include host innate and adaptive immune responses, parasite genome structure
and gene expression, antigenic variability, immune evasion, epidemiology and evolution,
population genetics and vector-pathogen interactions.
Each topic will be covered in a three-part fashion: 1) brief introduction of the pathogen life
cycle, 2) reading and discussion of assigned articles with a NYU faculty member that will lead
the discussion. This will help students understand and participate in the subsequent lecture;
and 3) a general review lecture by an expert on the topic followed by discussion with the
students. Speakers will include faculty from other universities and NYU School of Medicine.
Students are expected to participate actively in the discussion of the assigned research
articles.
Course directors:
Ana Rodriguez
(263 6757)
ana.rodriguez@nyumc.org
P’ng Loke
(263-8161)
Png.Loke@nyumc.org
Offered every year in the Fall.
3 credits
Location:
341 East 25th Street (at 1st Avenue), Old Public Health Building, 1st Floor Seminar Room
Host-Pathogen Interactions
Schedule:
Monday
Thursday
3:00 pm to 5 pm
2:00 pm to 5 pm
Lecture and discussion with the speaker.
Lectures and discussion. Discussion of
articles.
Schedule for the 2015 course:
September
21
Monday
September
24
Thursday
P’ng Loke
September
28
Monday
October 1
Thursday
P’ng Loke
Immune response
to helminths
Joel Ernst
Mycobacterium
immune response
October 5
Monday
Ken Cadwell
October 8
Thursday
Kirk Deitsch
Trans-kingdom
immune
interactions
Antigenic variation
in parasites
October 12
Monday
October 15
Thursday
Victor Torres
Bacterial toxins
Elizabeth
Nardin
Malaria vaccines
October 19
Monday
Sam Wassmer
October 22
Thursday
Andrew Read
Cerebral malaria
and antigenic
variation
Evolution of
resistance and
tolerance to
Ana Rodriguez
Introduction to
host-parasite
interactions
Malaria immune
response
Lecture and
discussion
2
Discussion of
articles, lecture
and discussion
with speaker
Lecture and
discussion
Student
Presentation
Discussion of
articles, lecture
and discussion
with speaker
Lecture and
discussion
Student
Presentation
Discussion of
articles, lecture
and discussion
with speaker
Lecture and
discussion
Discussion of
articles, lecture
and discussion
with speaker
Lecture and
discussion
Student
Presentation
Discussion of
articles, lecture
and discussion
Seminar
3
2
3
2
3
2
Student
Presentation
3
2
3
October 26
Monday
Jayne Raper
October 29
Thursday
Peter Bradley
November 2 Ana Rodriguez
Monday
November 5 Moriya Tsuji
Thursday
November 9 Jeff Weiser
Monday
November
16
Monday
EXAM
pathogens
Cell biology and
innate immunity to
African
Trypanosomes
Toxoplasma host
cell interactions
Drug discovery
against parasitic
diseases
Adjuvants
Co-infections and
immune evasion of
bacterial pathogens
with speaker
Lecture and
discussion
2
Seminar, lecture
and discussion
with speaker
Lecture and
discussion
Seminar
Discussion of
articles, lecture
and discussion
with speaker
Lecture and
discussion
Student
Presentation
3
2
3
2
3