Table S4. The inhibitory rate of tumor growth by individual TCHM in lung cancer human
xenograft or mouse allograft models
Herb names
Compounds
/Extracts
LC50
(μg/ml)
Cells
injected
in mice
Days
Dosage
(mg/kg/
day)
Inhibitory
rate
Ref.
Bupleurum scorzonerifolium
Isochaihulactone
7.37
A549
30
50
91.67%
[14]
Galla rhois
PGG
70.55
LLC
15
20
91.00%
[56]
Selaginella tamariscina
Extract
42.5
LLC
40
3000
79.00%
[49]
Andrographis paniculata
Andrographolide
14.02
CL1-5
42
4
78.14%
[27]
Bupleurum scorzonerifolium
Acetone extract
60
A549
20
500
73.33%
[57]
Daphne genkwa
Total flavonoids
NR
LLC
14
75
72.10%
[58]
Actinidia chinensis
Ethyl acetate extract
100
A549
26
1000
71.40%
[59]
Reynoutria japonica
Resveratrol
3.61
A549
15
60
68.42%
[10]
Bupleurum scorzonerifolium
Z-isochaihulactone
1.99
A549
37
30
66.67%
[6]
Solanum nigrum
SNSA
NR
LLC
14
8
65.90%
[60]
Salvia miltiorrhiza
Tanshinone IIA
1.5
A549
20
20
65.51%
[61]
Algae
Sulfated
polysaccharide
NR
LLC
10
80
65.41%
[62]
Curcuma phaeocaulis
Volatile oil
15.5
LLC
21
100
63.89%
[63]
Ferula assafoetida
Farnesiferol c
NR
LLC
12
1
59.71%
[64]
Millettia extensa
Extract
NR
LLC
10
28.4
58.70%
[65]
Pedicularis triangularidens
Extract
NR
LLC
12
60000
58.26%
[65]
Bolbostemma paniculatum
Tubeimoside-1
NR
LLC
14
3
58.00%
[66]
Reynoutria japonica
Resveratrol
2.03
LLC
20
100
54.58%
[67]
Sargassum fusiforme
Polysaccharide
500
A549
28
200
52.07%
[68]
Lindera strychifolia
Water extract
250
LL-2
28
5
51.01%
[69]
Reynoutria japonica
Resveratrol
2.03
LLC
20
10
49.66%
[70]
Citrus reticulata
Nobiletin
23.85
LLC
13
300
43.70%
[34]
Ligusticum sinense
TMPZ
NR
LLC
20
100
43.10%
[71]
Sophora flavescens
Matrine
NR
LLC
21
150
39.44%
[72]
Hedyotis diffusa
Extract
>40000
LLC
14
2500
38.33%
[73]
Caesalpinia sappan
Extract
NR
LLC
10
4.5
37.07%
[64]
Ligusticum sinense
TMPZ
NR
LLC
14
100
35.60%
[74]
Panax notoginseng
25-OCH3-PPD
2.4
A549
42
10
35.00%
[8]
Tetrastigma hemsleyani
Ethyl acetate extract
NR
LLC
14
25000
34.85%
[8]
Fagopyrum dibotrys
Fr4
NR
LLC
7
800
34.70%
[75]
Paris polyphylla
Saponin-1
1.58
LA795
14
100
29.44%
[5]
Scutellaria baicalensis
Baicalin
12.77
A549
21
50
26.64%
[53]
Salvia miltiorrhiza
Tanshinone IIA
1.5
LLC
10
15
25.65%
[76]
Caesalpinia sappan
Extract
NR
LLC
21
5000
22.53%
[77]
Panax ginseng
Ginsenoside Rh2
NR
LLC
11
20
20.00%
[78]
Cordyceps sinensis
Extract
NR
LLC
27
200
19.77%
[79]
Ligusticum sinense
Extract
NR
LLC
10
14
18.00%
[64]
NR: not reported.
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