DR SC. BILJANA (MOMČILO) OTAŠEVIĆ, SURNAME AT BIRTH JOCIĆ
DATE AND PLACE OF BIRTH 20.07.1977., Zemun, Serbia
EDUCATION
1992.
Finished elementary school in Zemun
1996.
Finished high school oriented on naturally sciences in Zemun
2003.
Graduated on University of Belgrade – Faculty of pharmacy
2004.
Passed state exam for pharmacists in Ministry of health of Republic of Serbia
2011.
Doctor of medical sciences – pharmacy
Doctoral thesis prepared under supervision of prof. dr Mira Zečević with the title
Multifactorial regresion analysis and multicriterial evaluation of liquid chromatographic
method used for investigation of eletriptan hydrobromide and rizatriptan benzoate, their
impurities and stability assesment and finished on December 8th 2011 In Department of
drug analysis, University of Belgrade – Faculty of pharmacy
2012.
Enrolled with healthcare specialist studies, programme Investigation and control of drugs
organized by University of Belgrade – Faculty of pharmacy
COURSES
2007.
Workshop entitled New perspectives for fast HPLC using two micron packing material,
broader pressure, flow and temperature range of analytical equipment on Agilent
1200RR system, October 26-30th 2007, Ohrid, Macedonia
2008.
Course entitled VI Summer School of liquid chromatography – mass spectrometry,
October 1-2nd 2008, Faculty of technology and metallurgy, Belgrade, Serbia
2010.
Seminar entitled Transfer of analytical methods HPLC-UHPLC-UPLC, September 9th
2010, Belgrade, Serbia
2011.
Course of continuous education entitled Upgraded technique of liquid chromatography
with ultra-high performances – UHPLC technique – importance and application, October
7-10th 2011, University of Belgrade – Faculty of pharmacy
2012.
Course of continuous education entitled Validations in pharmaceutical industry, October
6th 2012, University of Belgrade – Faculty of pharmacy
AWARDS AND SCHOLARSHIPS
1998.
Student scholarship awarded by Ministry of education of Republic of Serbia
1
2000.
Scholarship and diploma For the promising generation awarded by the Embassy of
Kingdom of Norway in Belgrade dedicated to the best candidates from the universities in
Republic of Serbia
2003. and 2004.
Scholarship for postgraduate studies for young talents awarded by the
Ministry of science and environmental protection of Republic of Serbia
WORKING EXPERIENCE
2003-2004.
Internship for pharmacists
State pharmacy Beograd, City office for health prevention, Central hospital pharmacy
of Clinical centre of Serbia, Department of pharmacy of Serbia, Belgrade
2005-2007.
Associate on course Drug analysis within basic graduate studies
Institute of pharmaceutical chemistry and drug analysis, University of Belgrade –
Faculty of pharmacy
2007-2010.
Teaching assistant on course Drug analysis within basic graduate studies
Institute of pharmaceutical chemistry and later on Institute of drug analysis,
University of Belgrade – Faculty of pharmacy
2010-2013.
Teaching assistant on mandatory course Pharmaceutical analysis and elective
courses Regulatory affairs in drug control, Experimental design in pharmaceutical
analysis and Sport pharmacy within integrated academic studies. Involved in
realisation of practical training on specialist academic studies Pharmacy 3 – module
Drug release on market for the courses Pharmaceutical analysis and Application of
optimization techniques in pharmaceutical research and development as well as
Pharmacy 2 – module Cosmetology for the course Investigation and control of
cosmetic products
Department of drug analysis, University of Belgrade – Faculty of pharmacy
26.02.2013.
Assistant professor on specific scientific field Drug analysis
Department of drug analysis, University of Belgrade – Faculty of pharmacy
TEACHING ACTIVITIES
Integrated academic studies
Participates in curriculum supplementation, gives lectures and performs practical training
on course Drug analysis, Experimental design in pharmaceutical analysis and Regulatory
affairs in drug control. Participates in preparation of curriculum for practical training and
performs practical training on course Sport pharmacy.
Specialist academic studies
Pharmacy 3 – module Release of medical product on market:
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Participates in curriculum supplementation, gives lectures and performs practical
teaching on course Pharmaceutical analysis; Participates in realisation of practical
training on courses Application of optimization techniques in pharmaceutical research
and development; Participates in curriculum supplementation and gives lectures on
course Packing materials and containers
Academic doctoral studies
Module Drug analysis: involved in realisation of teaching on all courses of the module
Mentor of one ongoing doctoral thesis and the member of the commission for the evaluation of
one finished doctoral thesis
Mentor of 5 final exams on integrated academic studies
Member of the commissions for the evaluation of 16 final exams on basic undergraduate studies
and of 23 final exams on integrated academic studies
SUPPORT OF EXTRACURRICULAR ACADEMIC STUDENT ACTIVITIES ON FACULTY OF PHARMACY
AND/OR UNIVERSITY OF BELGRADE
Mentor of 6 student research projects within Centre of student scientific research work on
University of Belgrade – Faculty of pharmacy which were presented on national meeting 50th and
55th. Congress of students of biomedical sciences
Member of Expert Committee of Seventh student mini-congress in charge of evaluation of the
presentations belonging to the field of drug analysis, analytical chemistry and instrumental
methods in organization of Centre of student scientific research work and Student parliament on
University of Belgrade – Faculty of pharmacy
PARTICIPATION IN REALISATION OF COURSES OF CONTINUOUS EDUCATION
2012.
Moderator of workshop entitled Evaluation of validation results on practical example
within the course Validations in pharmaceutical industry, October 6th 2012, Faculty of
pharmacy, Belgrade
LECTURER ON PROFESSIONAL SEMINARS AND MEETINGS
2014.
VI congress of pharmacists of Serbia with international participation, October 15-19th
2014, Belgrade, Serbia. The title of the lecture: The use of modern hyphenated techniques
in the development of methods aimed for stability evaluation of drugs
PARTICIPATION IN PROFESSIONAL GROUPS IN FACULTY OF PHARMACY
2008.
Member of commission nominated to monitor the student enrolment with the first
academic year of basic undergraduate studies and integrated academic studies
3
2013.
Member of commission in charge with the quality evaluation of one candidate to be
elected in research rank
2013.
Member of commission for monitoring and quality improvement of postgraduate studies
2013.
Member of commission nominated to perform inventory activities
RESEARCH ACTIVITIES
The main scientific research interest of Biljana Otašević is based on investigation of
pharmacologically active compounds, impurities and degradation products in pharmaceutical
dosage forms as well as their stability evaluation within forced degradation studies involving the
reversed-phase high pressure and ultra-high pressure liquid chromatography with different
detection systems and mass spectrometry. Besides, her research activities are related to extraction
techniques used for preparation and purification of biological materials aimed for investigation of
drugs and their metabolites. Chemometric approach is involved in analytical method development
and validation by means of experimental design, multi-criteria decision making methodology and
artificial neural network. Lately, her work was supplemented with the investigation of quantitative
relations between chemical structure and retention behaviour of group of compounds in
chromatographic system (QSRR studies).
SCIENTIFIC WORK
Published 4 paper in national journal (M52 category assigned by the Ministry of science of
Republic of Serbia) and 18 papers in international journals among which 7 papers is published in
journal with M21 category, 1 paper in M22 category journal, 9 papers in M23 category papers and
1 paper in international paper without assigned M category
Participated on international conferences with 27 presentations (4 published proceedings and 23
abstracted presentations) and on national conferences with 9 abstracted presentations. Presenter of
one lecture on national conference which was abstracted in conference abstract book
According
to
SCOPUS
data
base
concerning
the
author
citations
(http://www.scopus.com/home.url) last visited on February 12th 2014, cited 82 times (without
self-citations). h - Index 6
Reviewer for the journal Acta chromatographica (ISSN 1233-2356, journal category M23) and
journal Chromatographia (ISSN 1612-1112, category M23)
Participated in realisation of First QP conference: How to answer QP challenges in south-east
European countries held in Silver Lake, Veliko gradište, Serbia in October 3-4th 2013
PARTICIPATION ON SCIENTIFIC RESEARCH PROJECTS
2003.
Researcher with scholarship on - national scientific research project entitled Molecular
structure, chemical transformation, physical-chemical characterisation, pharmaceutical
4
purity and analysis of pharmacologically active compounds (no. 1458) financed by the
Ministry of science and environmental protection of Republic of Serbia (12 research
months)
2006.
Associate on national scientific research project entitled Synthesis, quantitative
relationship structure/properties and activity, physical-chemical characterisation and
analysis of pharmacologically active substances (no. 142071B) financed by the Ministry
of science and environmental protection of Republic of Serbia (8 research months)
2011.
Associate on national scientific research project entitled Synthesis, quantitative
relationship between structure and activity, physical-chemical characterisation and
analysis of pharmacologically active substances (no. 172033) financed by the Ministry
of education and science of Republic of Serbia (8 research months)
SELECTED PUBLICATIONS
1. Biljana Otašević, Svetlana Milovanović, Mira Zečević, Jelena Golubović, Ana Protić.
UPLC Method for Determination of Moxonidine and Its Degradation Products in Active
Pharmaceutical Ingredient and Pharmaceutical Dosage Form. Chromatographia 2014;
77(1-2): 109-118. M23
2. Jelena Golubović, Ana Protić, Mira Zečević, Biljana Otašević, Marija Mikić. Artificial
neural networks modelling in UPLC method optimization of mycophenolate mofetil and
its degradation products. Journal of chemometrics 2014; 28: 567-574. M23
3. Jelena Golubović, Ana Protić, Mira Zečević, Biljana Otašević, Ljiljana Živanović.
Quantitative structure–retention relationships of azole antifungal agents in reversed-phase
high performance liquid chromatography. Talanta 2012; 100: 329-337. M21
4. Svetlana Milovanović, Biljana Otašević, Mira Zečević, Ljiljana Živanović, Ana Protić.
Development and validation of reversed phase high performance liquid chromatographic
method for determination of moxonidine in presence of its impurities. Journal of
Pharmaceutical and Biomedical Analysis 2012; 59: 151-156. M21
5. Biljana Jocić, Mira Zečević, Ljiljana Živanović, Ana Protić, Milka Jadranin, Vlatka Vajs.
Study of forced degradation behavior of Eletriptan hydrobromide by LC and LC–MS and
development of stability-indicating method. Journal of Pharmaceutical and Biomedical
Analysis 2009; 50: 622-629. M21
6. Ljiljana Živanović, Ana Protić, Mira Zečević, Biljana Jocić, Mirjana Kostić. Multicriteria
optimization methodology in development of HPLC separation of Mycophenolic acid and
Mycophenolic acid glucuronide in human urine and plasma. Journal of Pharmaceutical and
Biomedical Analysis 2009; 50: 640-648. M21
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7. Predrag Džodić, Ljiljana Živanović, Ana Protić, Mira Zečević, Biljana Jocić.
Chemometrically assisted development and validation of HPLC method for simultaneous
determination of carbamazepine and its impurities iminostilbene and iminodibenzyl in
solid dosage form. Chromatographia 2009; 70: 1343-1351. M23
8. Mira Zečević, Biljana Jocić, Ljiljana Živanović, Ana Protić. Application of Multicriteria
Methodology in the Development of Improved RP-LC-DAD for Determination of
Rizatriptan and Its Degradation Products. Chromatographia 2008; 68: 911-918. M23
9. Ljiljana Živanović, Ana Ličanski, Mira Zečević, Biljana Jocić, Mirjana Kostić. Application
of experimental design in optimization of solid phase extraction of mycophenolic acid and
mycophenolic acid glucuronide from human urine and plasma and SPE-RP-HPLC method
validation. Journal of Pharmaceutical and Biomedical Analysis 2008; 47: 575-585. M21
10. Biljana Jocić, Mira Zečević, Ljiljana Živanović, Ana Ličanski. A chemometrical approach
to optimization and validation of an HPLC assay for rizatriptan and its impurities in tablets.
Analytical letters 2007; 40 (12): 2301-2316. M23
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