MEDICAL TERMINOLOGY: RENAL DISEASE Renal-Root Words & Combing Forms Calyx-cuplike division of the kidney Cortex-outer layer of kidney Glomerul/o-glomerula Medulla-inner or central portion of the kidney Nephr/o-kidney Pyel/o-kidney Py/o-pus Ur/o-urine Ren/o-kidney Renal-Anatomical Terms Afferent arteriole- carrying blood to the designated site, the glomerulus Bowman’s capsule-glomerular capsule; the expanded beginning of a nephron composed of inner and outer layers Collecting tubule- tubular segment of the renal collecting duct system that connects the distal convoluted tubule to the cortical collecting duct. Distal convoluted tubule- portion of kidney nephron between the loop of Henle and the collecting duct system Efferent arteriole- Conducting fluid or a nerve impulse outward from the arteriole Glomerular capsule- Bowman’s capsule; the expanded beginning of a nephron composed of inner and outer layers Glomerlus- a tuft formed of capillary loops at the beginning of each nephric tubule in the kidney Kidney-One of the paired organs that excrete urine, remove nitrogenous wastes of metabolism, reclaim important electrolytes and water, contribute to blood pressure control and erythropoiesis Loop of Henle- the U-shaped part of the nephron extending from the proximal to the distal tubules Nephron (renal tube)-basic functioning unit of the normal kidney; each nephron has two main parts; the glomerulus and the tubule Proximal convoluted tubule- portion of the duct system of the nephron of the kidney which leads from Bowman's capsule to the loop of Henle Renal cortex- the part of the kidney consisting of renal lobules in the outer zone beneath the capsule and the lobules of the renal columns that are extensions inward between the pyramids; contains the renal corpuscles, medullary rays, and proximal and distal convoluted tubules Renal medulla-the inner, darker portion of the kidney parenchyma consisting of the renal pyramids. Renal papillae-the apex of a renal pyramid that projects into a minor calyx; some 10–25 openings of papillary ducts occur on its tip, forming the area cribrosa. Renal pelvis- a flattened funnel-shaped expansion of the upper end of the ureter receiving the calices, the apex being continuous with the ureter. Renal-Physiological Terms Aldosterone-hormone made by the adrenal gland that regulates the balance of salt and water in the body Angiotension-protein whose presence in the blood promotes aldosterone secretion and tends to raise blood pressure Antidiuretic hormone-works to limit the output of fluid from the kidneys, constrict blood vessels, and raise blood pressure Bicarbonate-regulating vital functions and one of the important buffers necessary to maintain normal acid-base balance in the body Carbonic acid-H2CO3, formed from H20 and CO2 Diuretic-increase the flow of urine, which causes the body to get rid of excess water Erythropoietin-hormone produced in the kidney that regulates marrow production of red blood cells Glomerular filtration rate (GFT)-filtration ability of the glomerulus, index of kidney function, normal value about 125 mL/min Renin- hormone made by the kidneys that helps regulate the volume of fluid in the body and blood pressure Renal-Symptomatic Terms Acetonuria-presence of acetone in the urine Academia-condition of excess acid in the blood consistent with a pH less than7.35 Albuminuria-presence of excessive protein in the urine Anuria-failure of kidneys to produce urine Azotemia-buildup of nitrogenous waste products such as urea in the blood and body fluids Dysuria-painful or difficult urination Hematuria-the presence of blood in the urine Hyperkalemia-high serum potassium Micturition-the discharge of urine Nocturia-excessive urination at night Oliguria-urine output less than 400mL, which is the min amount of normal urine that can carry away the daily load of metabolic waste products Proteinuria-presence of too much protein in the urine Pyruia-the presence of pus in the urine, typically from bacterial infection Renal insufficiency (renal shut-down, lower nephron nephrosis)-insufficient excretion of wastes by the kidneys Renal osteodystrophy-refers to bone disease related to CKD, caused by over-production of PTH or by exposure to aluminum Renal-Diagnostic Terms Acidosis-conditions that produce excess acid in the blood Arteriolar nephrosclerosis- renal scarring caused by arteriolar sclerosis resulting from longstanding hypertension Glomerulonephritides- Renal disease characterized by diffuse inflammatory changes in glomeruli that are not the acute response to infection of the kidneys Hypertrophy of kidney- increased size of the kidney Nephritic syndrome- the clinical symptoms of acute glomerulonephritis, particularly hematuria, hypertension, and renal failure Nephrolithiasis (renal calculi)- Presence of renal calculi Nephromegaly- Extreme hypertrophy of one or both kidneys Nephrosclerosis- Fibrosis of the kidney from overgrowth and contraction of the interstitial connective tissue Pyelonephritis- Inflammation of the renal parenchyma, calyces, and pelvis, particularly due to local bacterial infection. Uremia- An excess of urea and other nitrogenous waste in the blood; The complex of symptoms due to severe persisting renal failure that can be relieved by dialysis Renal-Operative Terms Nephrectomy- Removal of a kidney Nephrolithotomy- Incision into the kidney for the removal of a renal calculus Nephrostomy- Establishment of an opening between the collecting system of the kidney through its parenchyma to the exterior of the body; may be performed by surgical incision or be placed percutaneously Nephrotomy- Incision into the kidney Pyelolithotomy- Operative removal of a calculus from the kidney through an incision in the renal pelvis Pyeloplasty- Surgical reconstruction of the renal pelvis and ureter to correct an obstruction at the ureteropelvic junction. Pyeltomy- Incision into the pelvis of the kidney. Renal biopsy- medical procedure in which a small piece of kidney is removed from the body for examination Renal transplantation- transplantation of a kidney from a compatible donor to restore kidney function in a recipient suffering from renal failure. Renal-Special Procedures Arterio-venous shunt- the passage of blood directly from arteries to veins, without going through the capillary network. Dialysis- renal replacement procedure that removes excessive and toxic byproducts of metabolism from the blood, thus replacing the filtering function of healthy kidneys Hemodialysis-Dialysis of soluble substances and water from the blood by diffusion through a semipermeable membrane Peritoneal dialysis-removal from the body of soluble substances and water by transfer across the peritoneum, using a dialysis solution that is intermittently introduced into and removed from the peritoneal cavity Renal-Special Diagnostic Procedures Intravenous pyelography- former name for intravenous urography; radiography of kidneys, ureters, and bladder following injection of contrast medium into a peripheral vein Nephrogram-radiographic examination of the kidney after the intravenous injection of a water-soluable iodinated contrast material Nephrosonography-process of recording the kidney using sound, such as an ultrasound Pyleogram- X-ray of the kidenyes and ureters Ultrasonic laminograms of kidneyUrogram- The radiographic record obtained by urography Urography- Radiography of any part of the urinary tract (kidneys, ureters, or bladder). Renal-Abbreviations ADH-antidiuretic hormone A/G-albumin/globulin ratio Alb-albumin BUN-Blood urea nitrogen CAPD-continuous ambulatory peritoneal dialysis cath-catheter chr-chronic CRF-chronic renal failure ERPF-effective renal plasma flow ESRD-end stage renal disease fld-fatty liver dystrophy GBM-glomerular basement membrane GFR-glomerular filtration rate HDU-hemodialysis unit IVP-intravenous pyelography KUB-kidney, ureter, bladder LSK-liver spleen kidney NPN-non-protein nitrogen PDU-pediatric dialysis unit PSP-phenolsulfonphthalein PTH-parathyroid hormone RER-rough endoplasmic reticulum RPF-renal plasma flow RTA-renal tubular acidosis SUN-standard unit of nomenclature UA-urinalysis UTI-urinary tract infection