MSc in Molecular Medicine Pathways
News 2012
http://www.sheffield.ac.uk/molmed
New Cancer and Cardiovascular Pathways were introduced in 2011 to supplement the
Genetics, Experimental Medicine and †Neuroscience Pathways.
† The module structure of the Neuroscience Pathway changed in 2011.
Please see our website at http://www.sheffield.ac.uk/molmed for more information.
Cancer Pathway
Molecular Basis of Tumourigenesis and Metastasis How do
current examples to
failed molecular control pathways – all of which are
illustrate this approach and
features of cancer – contribute to cell proliferation, errors
we will explore how insights
in DNA repair, loss of cell cycle control, and the loss of the
from these studies can
essential pathways for cell suicide? How are molecularly
inform drug development.
targeted therapies starting to transform treatment?
Molecular Approaches to
Molecular Techniques in Cancer Research Which new
Cancer Diagnosis and
techniques and methodologies are currently
Treatment
revolutionising the molecular understanding of cancer?
How have molecular
From classic tumour biology to the recent use of genomics
insights into cancer helped
and the even more recent use of proteomics, how can we
research? How can
identify the molecular lesions that are essential for the
molecular oncology be used
survival and progression of different cancers? We will use
to improve screening
programmes? How does it currently help in cancer
diagnosis, treatment and prognosis? Can it yet be used to
select treatments? Examples will illustrate novel molecular
insights and you will learn about their clinical context.
Cardiovascular Pathway
Vascular Cell Biology is founded on research from the
Department of Cardiovascular Science. The module
explores the molecular mechanisms underlying
cardiovascular disease and is a primer for the next two
modules. We explore the cellular mechanisms, molecules
and signalling pathways that are involved in the pathology
of vascular diseases. Students will gain hands-on
experience in the laboratory of cell biology methods that
we use to understand vascular biology function. There is a
strong emphasis on using experimental approaches to test
hypotheses and on applying background knowledge to
assess experimental results.
for testing hypotheses
concerning molecular and
cellular mechanisms of
vascular diseases. We
explore the development of
classical and emerging
therapies. As an alternative,
students have the
opportunity to participate
in UK Home Office training
course modules 1-3, which
are needed for a Home
Office personal licence for
in vivo work in the UK.
Experimental Models of Vascular Disease examines the use
of model systems, including in silico, in vitro and in vivo,
Vascular Disease Therapy and Clinical Practice examines
how basic science is translated into clinical practice and
therapy. We cover global disease epidemiology, drugs for
the prevention and management of heart disease and
interventional procedures for treatment. We also discuss
ethical issues. Students will have the opportunity to visit
the cardiovascular and cardiology clinical departments and
observe management of patients including interventional
procedures like angioplasty and stenting.