Programme (updated 10/04/2015)
Thursday, April 16th
12h00 – 19h00
Arrival and registration
19h00 – 21h00
Get-together with diner
Friday, April 17th
08h45 – 09h00
09h00 – 09h35
Opening Session:
(01)
09h35 – 12h40
09h35 – 10h10
Narla, Mohandas (NY Blood Centre, USA) Red Cells: Past, Present and Future.
Session 1:
(02)
10h10 – 10h30
(03)
Biogenesis to Maturation.
Erythropoiesis
Kinet, Sandrina (Université de Montpellier, FRA) Metabolic control of erythroid differentiation.
Fowler, Velia (The Scripps Research Institute, USA) Red Blood Cell Cytoskeletal Dynamics from
10h30 – 10h50
(04)
Blanc, Lionel (Feinstein Institute for Medical Research, USA) Pomalidomide Modulates
Transcription Networks Regulating Human Erythropoiesis and Globin Switching: Implications for Treatment of
Hemoglobinopathies..
10h50 – 11h20
Coffee break
11h20 – 11h40
(05)
Peters, Luanne (The Jackson Laboratory, Bar Harbor, USA) Novel genetic modifiers of
embryonic globin expression in adult mice.
11h40 – 12h00
(06)
Flatt, Joanna (Bristol Institute for Transfusion Sciences, GBR) The expression of homozygous
South-East Asian Ovalocytic band 3 throughout erythropoiesis.
12h00 – 12h20
(07)
Reihani, Niloofar (Institut National de la Transfusion Sanguine, FRA) Gaucher disease : An
unexpected dyserythropoiesis
12h20 – 12h40
product.
(08)
Akker van den, Emile (Sanquin Institute, NLD) From in vitro erythropoiesis to a transfusion
13h00 – 14h00
Lunch
14h00 – 15h00
Poster Session with coffee
15h00 – 18h40
Session 2:
Red Cell Physiology (1)
15h00 – 15h35
(09)
Discher, Dennis (University of Pennsylvania, USA) Phagocytosis involves much more than just
‘Eat Me’ molecules: Cell rigidity and shape override CD47’s “self”-signaling in phagocytosis.
15h35 – 15h55
(10)
Svetina, Sasa (University of Ljubljana, SVN) The primary determinant of the lateral distribution
of the skeleton of the deformed red blood cell is the change of the membrane geometry.
15h55 – 16h15
(11)
Minetti, Giampaolo (Università di Pavia, ITA) Differential remodeling of plasma membrane
and membrane-skeletal components during in vivo aging of human erythrocytes.
16h15 – 16h45
Coffee break
16h45 – 17h20
(12)
Grygorczyk, Ryszard (Université de Montreal, CAN) Hemolysis is a primary ATP-release
mechanism in human erythrocytes.
17h20 – 17h40
and disease.
(13)
Huisjes, Rick (University Medical Center Utrecht, NLD) Red blood cell-derived vesicles in health
17h40 – 18h00
(14)
by Human Erythrocytes.
Vitvitsky, Victor (University of Michigan, USA) A Novel Pathway for Hydrogen Sulfide Oxidation
18h00 – 18h20
(15)
Wesseling, Mauro (University of Saarland, DEU) Measurement of Ca2+ content and PS
exposure in human red blood cells: some related problems.
18h20 – 18h40
(16)
Le Van Kim, Caroline (Institut National de la Transfusion Sanguine, FRA) The laboratory of
excellence GR-Ex, a unique french consortium investigating the red blood cell from genesis to death.
19h00
Dinner
Saturday, April 18th
09h00 – 12h40
Session 3:
Red Cell Pathophysiology (Malaria, anemia…)
09h00 – 09h35
(17)
Low, Philip S. (Purdue Center for Drug Discovery, USA) Characterization of a tyrosine kinase
signaling pathway in erythrocytes and its role in development of a new therapy for malaria.
09h35 – 10h10
(18)
Lasonder,Edwin (Plymouth University, GBR) The malaria phospho proteome of red blood cells.
10h10 – 10h30
blood cells.
(19)
Lavazec, Catherine (Institut Cochin, FRA) Mechanical properties of P. falciparum-infected red
10h30 – 11h00
Coffee break
11h00 – 11h20
(20)
Ostuni, Mariano (Institut National de la Transfusion Sanguine, FRA) Translocator protein
(TSPO) ligands stimulate protoporphyrin IX transport and reactive oxygen species production leading to the inhibition of P.
falciparum growth into red blood cells.
11h20 – 11h40
(21)
Langsley, Gordon (Institut Cochin, FRA) cAMP regulation of redox status in young versus old
red blood cells compared to Plasmodium falciparum-infected red blood cells.
11h40 – 12h00
(22)
Mouro-Chanteloup, Isabelle (Institut National de la Transfusion Sanguine, FRA) Stomatindeficient red blood cells (RBCs) exhibit a decrease of the anion exchanger (AE1) activity.
12h00 – 12h20
(23)
Da Costa, Lydie (Hopital R. Debré, FRA) Diamond-Blackfan anemia, lost in translation?
12h20 – 12h40
(24)
Yaddanapudi, Ravindranath (Wayne State University School of Medicine, USA) A case of KLF1
E325K CDA with transfusion dependent anemia - results from Exome sequencing studies.
13h00 – 14h00
Lunch
14h30 – 16h25
Session 4:
14h30 – 15h05
(25)
15h05 – 15h25
(26)
oxygen carrying capacity.
Red Cell Physiology (2)
Bernhardt, Ingolf (University of Saarland, DEU) Membrane transport: a historical overview.
Bogdanova, Anna (University of Zurich, CHE) Role of calcium in regulation of red blood cell
15h25 – 15h45
disease (1).
(27)
Egée Stéphane (Université Pierre et Marie Curie, FRA) Cationic conductances in health and
15h45 – 16h05
disease (2).
(28)
Amsellem, Anais (Université Pierre et Marie Curie, FRA) Cationic conductances in health and
16h05 – 16h25
(29)
Sadowska-Bartosz, Izabela (University of Rzeszow, POL) Effect of glycation by glucose and
ascorbic acid on human erythrocytes.
16h25 – 16h45
(30)
19h00
Kaestner, Lars (University of Saarland, DEU) Initial steps to get hands on rare anaemias.
Cocktail
Banquet
Sunday, April 19th
09h00 – 12h40
Session 5:
Red Cell Pathophysiology (Sickle Cell Disease)
09h00 – 09h35
(31)
Hebbel, Robert P. (University of Minnesota Medical School, USA) The red cell and sickle
disease pathology: Key unanswered questions.
09h35 – 10h10
(32)
Elion, Jacques (Institut National de la Transfusion Sanguine, FRA) Implication of adenosine
signalling pathways in sickle cell disease pathophysiology.
10h10 – 10h30
RBC.
(33)
Malik, Punam (Cincinnati Children’s Hospital Medical Center, USA) Angiotensin and the sickle
10h30 – 11h00
Coffee break
11h00 – 11h20
(34)
alloimmunization.
Yazdanbakhsh, Karina (New York Blood Center, USA) Immune control of sickle cell
11h20 – 11h40
(35)
El Nemer, Wassim (Institut National de la Transfusion Sanguine, FRA) Microfluidics for
investigating red blood cell mechanical properties.
11h40 – 12h00
(36)
Lefevre, Sophie (Institut National de la Transfusion Sanguine, FRA) Investigating
morphological, mechanical and adhesive properties of sickle red blood cells.
12h00 – 12h20
(37)
pathways in sickle cells
Alper, Seth L. (Harvard Medical School, USA) Revisiting volume regulatory and dehydration
12h20 – 12h40
(38)
Gibson, John (University of Cambridge, GBR) KCl cotransport in red blood cells from patients
with HbSC disease: predictors of severity
13h00 – 14h00
Lunch
14h00 – 15h00
Poster Session with coffee
15h00 – 18h40
Session 6:
Senescence, Storage, Transfusion
15h00 – 15h35
(39)
Singh, Shailja (Institut Pasteur, FRA) Signals and molecular arsenals involved in red blood cell
entry by the human malaria parasite.
15h35 – 16h10
(40)
Bruce, Lesley ( Bristol Institute for Transfusion Sciences, GBR) Potassium concentration in
stored red cell units - the effect of familial pseudohyperkalaemia.
16h10 – 16h30
(41)
Noizat-Pirenne, France (Etablissement Français de Sang, FRA ) The sickle cell disease
environment affects old stored red blood cells : consequences for blood transfusion.
16h30 – 17h00
Coffee break
17h00 – 17h20
(42)
Colin-Aronovicz, Yves (Institut National de la Transfusion Sanguine, FRA) Storage lesions
17h20 – 17h40
(43)
Magon, Nicholas (University of Geneva, CHE) Molecular mechanisms of erythrocyte aging.
17h40 – 18h00
(44)
Tarasev, Michael (Blaze Medical Devices Ann Harbor, USA) Use of RBC Mechanical Fragility to
assess blood damage due to medical devices, drugs,cell environment or pathologies.
18h00 – 18h20
(45)
Storry, Jill (Lund University, SWE) Biochemical characterisation of the newly-discovered
erythroid protein SMIM1/Vel
.
18h20 – 18h40
Business meeting
19h15
Dinner
Monday, April 20th
Leave after breakfast
Posters:
(50)
Back de, Djuna
Immune Adherence Clearance is dependent on RBC adhesion molecules.
(51)
Bianchi, Paola
Usefulness of laser-assisted optical rotational cell analyser (LORRCA) in the diagnosis of hereditary haemolytic anemias.
(52)
Bouyer, Guillaume
Phosphoproteome analysis of Plasmodium-falciparum infected human red blood cells
(53)
Brust, Matthias
Clustering of red blood cells in microcirculation.
(54)
Cueff, Anne
VDAC phenotypic plasticity in RBC membranes: monomers or dimers ?
(55)
Danielczok, Jens
Evidence for PIEZO 1 involvement in pressure-dependent Ca2+- increase in human red blood cells.
(56)
Flormann, Daniel
Rheological and optical investigation of red blood cell aggregation.
(57)
Hannemann, Anke
The clinical significance of KCl cotransport in red blood cells from patients with HbSC disease.
(58)
Hertz, Laura
The LPA Signalling Pathway in Red Blood Cells.
(59)
Koralkova, Pavla
Three novel missense mutations in PIEZO1 in eight patients with dehydrated hereditary stomatocytosis – implications for
genotype-to-phenotype correlation.
(60)
Meinderts, Sanne
Antibody-mediated phagocytosis of red blood cells by human neutrophils.
(61)
Pellegrin, Stéphanie
Manipulation of Red Cell Membrane Protein Expression.
(62)
Petkova-Kirova, Polina
An automated system to study ion channels in red blood cells.