Name: Date: Class Period: Infectious Diseases Human Body Lesson 7: Standard 10d. Students know there are important differences between bacteria and viruses with respect to their requirements for growth and replication, the body’s primary defenses against bacterial and viral infections, and effective treatments of these infections. Vocabulary 1. : any change, other than an injury, that disrupts the normal functions of the body 2. : a disease-causing agent 3. : the idea that microorganisms (germs) cause infectious diseases 4. : a series of rules used to identify the microorganism that causes a specific disease 5. : an animal that carries a pathogen from person to person 6. : compounds that kill bacteria without harming the cells of the human or animal host. They work by interfering with the cellular processes of microorganisms The Germ Theory of Disease Before the ________________________ ________________________ of disease, people believed that diseases were caused by curses, evil spirits, bad smells, and miasmas (stinky clouds and fogs). Now, we know that infectious diseases are caused by ________________________ (germs) 1 Koch’s Postulates Koch’s postulates are how scientists show that a specific microorganism causes a specific disease. 1. The pathogen should ________________________ be present in a sick organism and ________________________ be present in a healthy one 2. The pathogen must be ________________________ from a sick host organism in a laboratory and grown in ________________________ ________________________ 3. When the cultured pathogens are put into a new host, they should cause the ________________________ ________________________ that the original host organism had 4. The pathogen must be ________________________ from the second host and should be ________________________ to the original pathogen 2 Agents of Disease • Many microorganisms live in the human body ________________________ causing diseases. • Some microorganisms are even ________________________, such as the bacteria that live in your gut. • Other microorganisms may ________________________ cells or release ________________________ as they grow, causing ________________________. • Some disease-causing agents are carried to humans by ________________________ such as cats, mosquitos, and fleas Viruses • Viruses are ________-________________, ________________________ invaders • Viruses consist of just a protein coat called a ________________________, a ________________________ ________________________, and sometimes a bit of membrane that is stolen from the host cell • Viruses can infect almost every type of organism • Viruses inject their genetic material into the ________________________ cell where it goes to the nucleus and hijacks the cellular machinery. When many new viruses have been made, they are ________________________ from the cell. Sometimes the cell bursts when new viruses are released • Some viral diseases include the common cold, the flu, smallpox, warts, and HIV/AIDS 3 Bacteria • Most bacteria are harmless to humans There are two ways that bacteria can cause disease: 1. Some bacteria ________________________ ________________________ human tissues for food 2. Some bacteria release ________________________ that harm the body • Examples of bacterial diseases are strep infections, staph infections, diptheria, botulism, and anthrax. • Many bacterial diseases can be treated and cured with ________________________ Protists • Most protists that cause disease are also called parasites. They are ________________________. • ________________________ is a disease caused by a protist called Plasmodium that is carried by a mosquito ________________________. It causes cycles of fevers, chills, and sweats. It is deadly if left untreated • ________________________ disease is caused by the protist Typanosoma cruzi and carried by “kissing bugs” (the vectors). It causes lesions (sores) on the heart and slows down peristalsis, the movement that pushes partially digested food through your gut. Some researchers believe that Charles Darwin died of Chagas disease. 4 Worms • Worms are animals that can cause disease in humans. • Tapeworms and hookworms infect the gut. • From the 1900s to the 1950s, some people intentionally swallowed tapeworms to lose weight Fungi • Some fungi can also cause diseases in humans. • Tinea is a fungus that causes ________________________ ________________________. It can also infect the scalp and cause ________________________. • Other fungi can infect the mouth, throat, fingernails, and toenails. How Diseases are Spread • ________________________ ________________________: Touching Coughing on someone Sexual contact • ________________________ ________________________ and ________________________: Undercooked food Dirty water • ________________________ ________________________: Vectors carry diseases Ticks & fleas Reptiles Wild animals 5 Fighting Infectious Diseases • Antibiotics can kill ________________________ • Other prescription drugs can kill ________________________ and ________________________, though these are more difficult to kill • ________________________ -the________________________ drugs treat only the ________________________ of infections. They cannot cure diseases • ________________________ situations where you may contract a disease and ________________________ your ________________________ frequently can help ________________________ the spread of infectious diseases 6