HEMATOPOIETIC STEM CELL TRANSPLANT IN HOSPITAL AMPANG – FROM 1999 TO
2014
Ong Tee Chuan1, Guan Yong Khee2, Muhd Zanapiah Zakaria1, Jay Suriar Rajasuriar1, Jerome Tan1, Tan
Sen Mui1, Chang Kian Meng1
1
Hospital Ampang, Malaysia 2Hospital Melaka, Malaysia.
Background:
Hematopoietic stem cell transplant (SCT) is an important and effective treatment modality in various
Hematology diseases. SCT service for Ministry of Health was initiated in 1999 in Hospital Kuala Lumpur,
and moved to Hospital Ampang in 2006. We report our SCT experience over the last 15 years from 19992014.
Methods:
Copies of transplant protocol and discharge summary were archived in master file since 1999. From 2009
onwards patient’s information is kept in a standalone Microsoft Access application, and discharge
summaries are kept in the database. Since 2012 almost all transplant related paper works are being done
electronically via the same application. Data in this poster are extracted from the Microsoft Access
application.
Results:
1266 episodes of SCT were carried out from 1999-2014. 548 episodes were allogeneic SCT (including
matched sibling donor, matched unrelated donor, cord blood and haploidentical), while 718 episodes of
autologous SCT were done. Estimated 5 years overall survival from transplant is 65% for autologous SCT
and 51% for allogeneic SCT. Other statistics and data will be presented in the poster.
Conclusion:
SCT remains an important treatment modality for a variety of hematology diseases over the past few
decades. With the maturation of experience, ability to use reduced intensity conditioning, expansion of
unrelated donor and recently with feasibility of haploidentical donor, the cohort of patients eligible for SCT
has expanded markedly. In the era of multiple novel agents, the decision to use SCT remains as an evolving
challenge. Long term follow-up of local data is important to serve as a guide to clinicians for decision
making.
Keywords: Hematopoietic stem cell transplant