Incredible Technology: How to Bring Extinct
Animals Back to Life
Tanya Lewis, Staff Writer | August 19, 2013 08:05am ET
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This photo shows a museum worker inspecting a replica of a woolly mammoth.
Credit: Photo by Jonathan S. Blair/National Geographic
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Editor's Note: In this weekly series, LiveScience explores how technology drives scientific
exploration and discovery.
The passenger pigeon, the dodo and the woolly mammoth are just a few of the species wiped off
the Earth by changing environments and human activities.
Now, advances in biotechnology could enable scientists to bring extinct animals back from the
grave. But critics argue the practice would only hinder conservation efforts, by resurrecting
creatures that could not survive in the wild.
First popularized by Michael Crichton's novel "Jurassic Park," the process of de-extinction has
become more than a sci-fi concept. In 2003, biologists brought back a Pyrenean ibex by making
a clone of frozen tissues harvested from the last of these goats. The clone died within minutes of
its birth due to a lung deformity, but the experiment proved de-extinction was possible. [6
Extinct Animals That Could Be Brought Back to Life]
"We can use some of these techniques to actually help endangered species improve their longterm viability," said ecologist Stanley Temple of the University of Wisconsin-Madison. "Where
it gets controversial is when we start talking about species that have been extinct for a very long
period of time," Temple said.
Reviving the passenger pigeon
The passenger pigeon filled the skies of North America in flocks of millions during the 19th
century. But hunting and habitat destruction steered the birds to extinction. The world's last
passenger pigeon, Martha, died in 1914 at the Cincinnati Zoo in Ohio.
But what if scientists could bring them back? Writer and environmentalist Stewart Brand,
founder of the Whole Earth Catalog, and his wife Ryan Phelan, founder of the genetics company
DNA Direct, wondered if it were possible. Working with Harvard biologist George Church, they
figured out a possible way to revive passenger pigeons.
You can't simply clone a passenger pigeon museum specimen, because they no longer have fully
intact genomes. But there could be another way: Using fragments of the passenger pigeon DNA,
scientists could synthesize the genes for certain traits and splice the genes together into the
genome of a rock pigeon.
The cells containing the passenger pigeon DNA could be transformed into cells that produce
eggs and sperm, which could be injected into rock pigeon eggs. The pigeons that hatched would
be rock pigeons, but their offspring would resemble passenger pigeons. Scientists could then
breed these birds and select for specific traits, as a dog breeder might. Eventually the resulting
offspring would appear very much like the passenger pigeon.
But that's not the only extinct animal scientists have their sights on reviving.
Woolly mammoths next?
Other scientists dream of bringing back a beast that roamed the Earth hundreds of thousands of
years ago: the woolly mammoth. Well-preserved mammoths have been dug out of the Siberian
tundra containing bone marrow, skin, hair and fat. If a living mammoth cell were found, it could
be grown in a lab and coaxed to form an embryo. The embryo could be implanted into the closest
living relative of mammoths, an elephant, which would give birth to a baby mammoth. [Images:
25 Amazing Ancient Beasts]
Finding a living mammoth cell is very unlikely. But South Korean biomedical engineer Insung
Hwang hopes to find just a cell nucleus and produce a clone from it, like Dolly the sheep. The
nucleus would be implanted into an elephant egg whose nucleus had been removed. But this is
no easy feat — no one has yet successfully harvested an elephant egg.
The challenges aren't trifling. Even if researchers succeed in creating a mammoth, passenger
pigeon or other extinct creature, it has to survive in the wild. This means having the right food
and habitat, and evading predators — especially humans.
Conservation controversy
Critics of de-extinction say reviving extinct animals would do more harm to conservation efforts
than good.
"I don't think it has any merit at all," said conservation ecologist Stuart Pimm of Duke
University, N.C. "It totally ignores the very practical realities of what conservation is about."
The prospect of bringing species back from extinction would lead Congress to support the
destruction of natural habitats, because animals that go extinct could be revived in a lab, Pimm
told LiveScience.
Most species are going extinct in tropical forests, Pimm said. Saving a species through deextinction when humans are burning forests and destroying native communities is a joke, he said.
Biologist David Ehrenfeld of Rutgers, The State University of New Jersey, agrees de-extinction
would impede conservation. "It's very negative, very expensive and not going to achieve any
conservation goal as far as I can see," Ehrenfeld said.
For example, the passenger pigeon was a very social bird known to form flocks of millions.
When their numbers dwindled to a few thousand, the birds stopped breeding, Ehrenfeld told
LiveScience. De-extinction methods would produce just a handful of birds, so "who's to say they
would reproduce?" he said.
What's more, the pigeons that raised them would be a different species, with differing mothering
techniques. "The environment is different in every respect," Ehrenfeld said.
Temple took a more moderate view. "If we're going to try to do this seriously, it's probably in
everyone's best interest that the early attempts have a high probability of success," he said.
Resurrecting a creature like the passenger pigeon or woolly mammoth has a strong appeal to the
public's imagination, Temple said. "But the species that are often hyped don't meet those criteria
at all," he said.