Pedigree Project As we have learned, DNA is the universal code to all life. Genetics is the study of how that DNA is passed from generation to generation. During this project, we are going observe the inheritance patterns of human traits exhibiting complete dominance. To do so, we will examine ourselves to determine which trait we exhibit for each of the characteristics listed below. It will then be your responsibility to survey the appearance of your parents (and siblings if applicable) to discover if they exhibit the same phenotype as you. You will then use that information to investigate exactly how you acquired these traits as well as the biological explanation behind their expression. Feature Mouth Hair Cheek Chin Ear Hand Phenotype PTC paper tasting Tongue Rolling Widow’s peak Dimples Freckles Y-shaped fissure Lobe Little finger Mid-digit hair Dominant Taste Roll Having a widow’s peak Dimples Freckles Cleft Free Curved Hair Recessive No taste Cannot roll No peak No dimples No freckles No cleft Attached Straight No hair Procedure 1. With a partner, examine your appearance to determine if you exhibit the dominant or recessive version for each of the traits listed above. 2. Observe the phenotypes of your parents and that of every accessible member in your immediate family. (You will be provided with PTC paper as well as regular paper strips to be used as a control to take home with you.) Note: I realize that some of you may not have access to one or both your blood parents for a variety of reasons. If this is the case, then please examine the phenotypes of your guardian(s) (even if it is only 1 person). Even though this does not represent your actual heredity, it can still be intriguing to examine the similarities and/or differences you share with these individuals. You will answer the extension questions simply in a general sense without including specific example of your personal heredity. 3. Construct a pedigree for each of the traits listed demonstrating the inheritance patterns in your family. 4. You will now examine these pedigrees, and write a reflection demonstrating that you understand the mechanisms that have occurred to produce the similarities/differences you see between you and your family. After writing the reflection, answer the extension questions listed below to demonstrate your ability to apply the knowledge you described in your reflection. Reflection: 1. Begin by describing the biological process (meiosis) that occurs to allow traits to be passed from parent to offspring in sexually reproducing organisms. 2. Then, explain in as much detail as possible the molecular process that leads to the expression of your phenotype from the genotype you acquired from your parents. In other words, how do you take the DNA that you receive as a diploid zygote (receiving 1 haploid set from each parental gamete) and produce the phenotype that you see. Hint: discuss molecular biology (specifically protein synthesis). Include a description of the difference between the expression of a dominant and recessive trait in this discussion while citing specific examples from your phenotype. Application Questions 1. For some of these traits, both of your parents may have exhibited a different phenotype than you. Give an explanation for how these situations are possible citing the specific examples where this occurred with your family. (If there is not an example of this in your pedigrees then simply describe how this scenario could occur in general.) 2. Explain why for some of these traits we can be certain of your genotype but for others we cannot. (If there is not an example of this in your pedigrees then simply describe how this scenario could occur in general.) 3. As you study the phenotypes of your family, you will most likely notice that you share similarities with each of your parents. If you have siblings, you will observe similar results with them as well. Even so, it is unlikely that you display identical phenotypes for all of the characteristics listed with any of them. Choose one of these individuals. Explain in detail how it is possible for you to demonstrate similarities with them in certain aspects but to be different from them in others. In this description, include the following terms: law of independent assortment, law of segregation, crossing over, and random fertilization. a. In other words, for this question you are discussing exactly how meiosis gives us genetic variation. 4. Critique the following statement by giving a detailed explanation of your support or rebuttal. “A dominant trait is more likely to be found in a population.” If you disagree, describe how a trait actually becomes more common in a population.