Supplementary Table 1. Source information for the disease and autism association genetic databases used in this study.
Source
Description
Numbe Link
Comments
r of
genes
DISEASES – The Novo
Disease-gene associations mined
576
http://diseases.jen Selected genes
Nordisk Foundation Center for from literature
senlab.org/Search associated with
Protein Research at the
“Autistic disorder”,
University of Copenhagen
[DOID:12849]
Genetic Association Database
Human genetic association studies of 373
http://geneticasso Selected genes
(GAD) – Center for
complex diseases and disorders
ciationdb.nih.gov/ associated with
Information Technology,
cgi-bin/index.cgi “autism” phenotype
National Institutes of Health
HuGE Navigator Phenopedia – An integrated, searchable knowledge 401
http://www.hugen Selected genes
Centers for Disease Control
base of genetic associations and
avigator.net/HuG associated with
and Prevention
human genome epidemiology
ENavigator/home “Autistic disorder”
.do
Malacards – Crown Human
An integrated database of human
224
http://www.malac Selected genes
Genomics Center and the
maladies and their annotations,
ards.org/
associated with
Bioinformatics Unit of the
modeled on the architecture and
“Autism spectrum
Weizmann Institute of Science richness of the popular GeneCards
disorder”
database of human genes
AutDB - MindSpec
An integrated catalogue of human
315
http://autism.min Selected human genes
genetic studies related to autism
dspec.org/autdb/
Welcome.do
AutismKB – Center for
An evidence based knowledgebase of 181
http://autismkb.cb Combined “Core” and
Bioinformatics, Peking
autism genetics
i.pku.edu.cn/
“Syndromic”
University
categories
Autism Genetic Database
A comprehensive database for autism 202
http://wren.bcf.ku Selected all genes
(AGD)
susceptibility gene-CNVs integrated
.edu/
with known noncoding RNAs and
fragile sites
“A Brain Region-Specific
Autism candidate genes generated by 464
http://www.ploso Selected Table S9.
Predictive Gene Map for
filtering the human genome with
ne.org/article/auth Set of 460
Autism Derived by Profiling a
Reference Gene Set”
expression/functional profiles of 84
significant autism susceptibility
genes from AutDB
“A noise-reduction GWAS
analysis implicates altered
regulation of neurite outgrowth
and guidance in autism”
Autism candidate genes generated by
human GWAS analysis with
statistical noise reduction to decrease
false positives
761
ors/info%3Adoi%
2F10.1371%2Fjo
urnal.pone.00284
31
http://www.molec Selected Table S4.
ularautism.com/c
ontent/2/1/1